Six weeks' aerobic retraining after two weeks' immobilization restores leg lean mass and aerobic capacity but does not fully rehabilitate leg strenght in young and older men
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Six weeks' aerobic retraining after two weeks' immobilization restores leg lean mass and aerobic capacity but does not fully rehabilitate leg strenght in young and older men. / Vigelsø Hansen, Andreas; Gram, Martin; Wiuff, Caroline; L. Andersen, Jesper; Helge, Jørn Wulff; Dela, Flemming.
I: Journal of Rehabilitation Medicine, Bind 47, Nr. 6, 06.2015, s. 552-560.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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T1 - Six weeks' aerobic retraining after two weeks' immobilization restores leg lean mass and aerobic capacity but does not fully rehabilitate leg strenght in young and older men
AU - Vigelsø Hansen, Andreas
AU - Gram, Martin
AU - Wiuff, Caroline
AU - L. Andersen, Jesper
AU - Helge, Jørn Wulff
AU - Dela, Flemming
PY - 2015/6
Y1 - 2015/6
N2 - OBJECTIVE: To determine the effect of aerobic retraining as rehabilitation after short-term leg immobilization on leg strength, leg work capacity, leg lean mass, leg muscle fibre type composition and leg capillary supply, in young and older men.SUBJECTS AND DESIGN: Seventeen young (23 ± 1 years) and 15 older (68 ± 1 [standard error of the mean; SEM] years) men had one leg immobilized for 2 weeks, followed by 6 weeks' bicycle endurance retraining.METHODS: Maximal voluntary contraction, leg work capacity (Wmax), and leg lean mass by dual energy X-ray absorptiometry were measured at inclusion, after immobilization and after 3 and 6 weeks' retraining. Muscle biopsies were evaluated for fibre type, fibre area, and capillarization.RESULTS: Immobilization decreased maximal voluntary contraction (-28 ± 6% and -23 ± 3%); Wmax (-13 ± 5% and -9 ± 4%) and leg lean mass (only in young, -485 ± 105 g) in young and older men, respectively. Six weeks' retraining increased maximal voluntary contraction (34 ± 8% and 17 ± 6%), Wmax (33 ± 5% and 20 ± 5%) and leg lean mass (only in young 669 ± 69 g) in young and older men, respectively, compared with the immobilized value.CONCLUSION: Short-term leg immobilization had marked effects on leg strength, and work capacity and 6 weeks' retraining was sufficient to increase, but not completely rehabilitate, muscle strength, and to rehabilitate aerobic work capacity and leg lean mass (in the young men).
AB - OBJECTIVE: To determine the effect of aerobic retraining as rehabilitation after short-term leg immobilization on leg strength, leg work capacity, leg lean mass, leg muscle fibre type composition and leg capillary supply, in young and older men.SUBJECTS AND DESIGN: Seventeen young (23 ± 1 years) and 15 older (68 ± 1 [standard error of the mean; SEM] years) men had one leg immobilized for 2 weeks, followed by 6 weeks' bicycle endurance retraining.METHODS: Maximal voluntary contraction, leg work capacity (Wmax), and leg lean mass by dual energy X-ray absorptiometry were measured at inclusion, after immobilization and after 3 and 6 weeks' retraining. Muscle biopsies were evaluated for fibre type, fibre area, and capillarization.RESULTS: Immobilization decreased maximal voluntary contraction (-28 ± 6% and -23 ± 3%); Wmax (-13 ± 5% and -9 ± 4%) and leg lean mass (only in young, -485 ± 105 g) in young and older men, respectively. Six weeks' retraining increased maximal voluntary contraction (34 ± 8% and 17 ± 6%), Wmax (33 ± 5% and 20 ± 5%) and leg lean mass (only in young 669 ± 69 g) in young and older men, respectively, compared with the immobilized value.CONCLUSION: Short-term leg immobilization had marked effects on leg strength, and work capacity and 6 weeks' retraining was sufficient to increase, but not completely rehabilitate, muscle strength, and to rehabilitate aerobic work capacity and leg lean mass (in the young men).
U2 - 10.2340/16501977-1961
DO - 10.2340/16501977-1961
M3 - Journal article
C2 - 25898161
VL - 47
SP - 552
EP - 560
JO - Journal of Rehabilitation Medicine
JF - Journal of Rehabilitation Medicine
SN - 1650-1977
IS - 6
ER -
ID: 138051326