Quantitation of glial fibrillary acidic protein in human brain tumours
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Quantitation of glial fibrillary acidic protein in human brain tumours. / Rasmussen, S; Bock, E; Warecka, K; Althage, G.
I: British Journal of Cancer, Bind 41, Nr. 1, 1980, s. 113-6.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Quantitation of glial fibrillary acidic protein in human brain tumours
AU - Rasmussen, S
AU - Bock, E
AU - Warecka, K
AU - Althage, G
N1 - Keywords: Albumins; Brain Neoplasms; Glioma; Humans; Immunoelectrophoresis; Neoplasm Proteins
PY - 1980
Y1 - 1980
N2 - The glial fibrillary acidic protein (GFA) content of 58 human brain tumours was determined by quantitative immunoelectrophoresis, using monospecific antibody against GFA. Astrocytomas, glioblastomas, oligodendrogliomas, spongioblastomas, ependymomas and medulloblastomas contained relatively high amounts of GFA, up to 85 times the concentration in parietal grey substance of normal human brain. GFA was not found in neurinomas, meningiomas, adenomas of the hypophysis, or in a single case of metastasis of adenocarcinoma. Non-glial tumours of craniopharyngioma and haemangioblastoma were infiltrated by reactive astroglia and showed considerable amounts of GFA.
AB - The glial fibrillary acidic protein (GFA) content of 58 human brain tumours was determined by quantitative immunoelectrophoresis, using monospecific antibody against GFA. Astrocytomas, glioblastomas, oligodendrogliomas, spongioblastomas, ependymomas and medulloblastomas contained relatively high amounts of GFA, up to 85 times the concentration in parietal grey substance of normal human brain. GFA was not found in neurinomas, meningiomas, adenomas of the hypophysis, or in a single case of metastasis of adenocarcinoma. Non-glial tumours of craniopharyngioma and haemangioblastoma were infiltrated by reactive astroglia and showed considerable amounts of GFA.
M3 - Journal article
C2 - 7362772
VL - 41
SP - 113
EP - 116
JO - The British journal of cancer. Supplement
JF - The British journal of cancer. Supplement
SN - 0007-0920
IS - 1
ER -
ID: 21607599