Problems in severe bilateral urinary tract anomalies
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Problems in severe bilateral urinary tract anomalies. / Thorup, Jørgen Mogens.
I: Progress in Pediatric Surgery, Bind 23, 1989, s. 81-5.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Problems in severe bilateral urinary tract anomalies
AU - Thorup, Jørgen Mogens
PY - 1989
Y1 - 1989
N2 - Management of children with severe infravesical or bilateral ureterovesical obstruction with or without reflux is difficult. Our experience over 10 years includes 29 such children, 19 of whom presented in the first 3 months of life. At the time of diagnosis, 13 had severe disturbance of renal function. There were two deaths. Five children have severe and two a moderate reduction of renal function; twenty good renal function. There were ten nephrectomies and four heminephrectomies. Seven patients had a temporary and eight a permanent urinary diversion. However, four of the latter were later undiverted. Removal of an obstruction is not always followed by full restitution of function. It seems probable that renal dysplasia and developmental injury to the ureterovesical musculature set a limit to the therapeutic possibilities. Careful management is important, especially in neonatal cases, where extensive reconstructive procedures are technically demanding and the rate of complications is high.
AB - Management of children with severe infravesical or bilateral ureterovesical obstruction with or without reflux is difficult. Our experience over 10 years includes 29 such children, 19 of whom presented in the first 3 months of life. At the time of diagnosis, 13 had severe disturbance of renal function. There were two deaths. Five children have severe and two a moderate reduction of renal function; twenty good renal function. There were ten nephrectomies and four heminephrectomies. Seven patients had a temporary and eight a permanent urinary diversion. However, four of the latter were later undiverted. Removal of an obstruction is not always followed by full restitution of function. It seems probable that renal dysplasia and developmental injury to the ureterovesical musculature set a limit to the therapeutic possibilities. Careful management is important, especially in neonatal cases, where extensive reconstructive procedures are technically demanding and the rate of complications is high.
KW - Child, Preschool
KW - Female
KW - Humans
KW - Infant
KW - Infant, Newborn
KW - Male
KW - Time Factors
KW - Ureteral Obstruction
KW - Urinary Tract
KW - Vesico-Ureteral Reflux
M3 - Journal article
C2 - 2499006
VL - 23
SP - 81
EP - 85
JO - Progress in Pediatric Surgery
JF - Progress in Pediatric Surgery
SN - 0079-6654
ER -
ID: 47629354