Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat.

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Standard

Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat. / Tønder, N; Johansen, Flemming Fryd; Frederickson, C J; Zimmer, J; Diemer, N H.

I: Neuroscience Letters, Bind 109, Nr. 3, 1990, s. 247-52.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Tønder, N, Johansen, FF, Frederickson, CJ, Zimmer, J & Diemer, NH 1990, 'Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat.', Neuroscience Letters, bind 109, nr. 3, s. 247-52.

APA

Tønder, N., Johansen, F. F., Frederickson, C. J., Zimmer, J., & Diemer, N. H. (1990). Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat. Neuroscience Letters, 109(3), 247-52.

Vancouver

Tønder N, Johansen FF, Frederickson CJ, Zimmer J, Diemer NH. Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat. Neuroscience Letters. 1990;109(3):247-52.

Author

Tønder, N ; Johansen, Flemming Fryd ; Frederickson, C J ; Zimmer, J ; Diemer, N H. / Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat. I: Neuroscience Letters. 1990 ; Bind 109, Nr. 3. s. 247-52.

Bibtex

@article{a395f9005e1211dd8d9f000ea68e967b,
title = "Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat.",
abstract = "The fluorescent dye 6-methoxy-8-p-toluene sulfonamide quinoline (TSQ) was used to monitor the distribution of zinc in the hippocampus and fascia dentata of adult rats subjected to 20 min of cerebral ischemia. In normal brains TSQ stains only neuropil, in particular the mossy fiber layers in the dentate hilus (CA4) and CA3, but within 2 h after ischemia, TSQ-fluorescent cells were observed in the dentate hilus. At longer survival times TSQ-positive cells stained positively with acid fuchsin, a sign of cellular degeneration. At the same time a decrease in the TSQ fluorescence of the mossy fiber terminals in the dentate hilus (CA4) and the CA3 mossy fiber layer was noted. The observations suggest that zinc many play a role in the selective death of dentate hilar neurons after cerebral ischemia.",
author = "N T{\o}nder and Johansen, {Flemming Fryd} and Frederickson, {C J} and J Zimmer and Diemer, {N H}",
note = "Keywords: Aminoquinolines; Animals; Fluorescent Dyes; Hippocampus; Ischemic Attack, Transient; Male; Rats; Rats, Inbred Strains; Sulfonamides; Tosyl Compounds; Zinc",
year = "1990",
language = "English",
volume = "109",
pages = "247--52",
journal = "Neuroscience letters. Supplement",
issn = "0167-6253",
publisher = "Elsevier Ireland Ltd",
number = "3",

}

RIS

TY - JOUR

T1 - Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat.

AU - Tønder, N

AU - Johansen, Flemming Fryd

AU - Frederickson, C J

AU - Zimmer, J

AU - Diemer, N H

N1 - Keywords: Aminoquinolines; Animals; Fluorescent Dyes; Hippocampus; Ischemic Attack, Transient; Male; Rats; Rats, Inbred Strains; Sulfonamides; Tosyl Compounds; Zinc

PY - 1990

Y1 - 1990

N2 - The fluorescent dye 6-methoxy-8-p-toluene sulfonamide quinoline (TSQ) was used to monitor the distribution of zinc in the hippocampus and fascia dentata of adult rats subjected to 20 min of cerebral ischemia. In normal brains TSQ stains only neuropil, in particular the mossy fiber layers in the dentate hilus (CA4) and CA3, but within 2 h after ischemia, TSQ-fluorescent cells were observed in the dentate hilus. At longer survival times TSQ-positive cells stained positively with acid fuchsin, a sign of cellular degeneration. At the same time a decrease in the TSQ fluorescence of the mossy fiber terminals in the dentate hilus (CA4) and the CA3 mossy fiber layer was noted. The observations suggest that zinc many play a role in the selective death of dentate hilar neurons after cerebral ischemia.

AB - The fluorescent dye 6-methoxy-8-p-toluene sulfonamide quinoline (TSQ) was used to monitor the distribution of zinc in the hippocampus and fascia dentata of adult rats subjected to 20 min of cerebral ischemia. In normal brains TSQ stains only neuropil, in particular the mossy fiber layers in the dentate hilus (CA4) and CA3, but within 2 h after ischemia, TSQ-fluorescent cells were observed in the dentate hilus. At longer survival times TSQ-positive cells stained positively with acid fuchsin, a sign of cellular degeneration. At the same time a decrease in the TSQ fluorescence of the mossy fiber terminals in the dentate hilus (CA4) and the CA3 mossy fiber layer was noted. The observations suggest that zinc many play a role in the selective death of dentate hilar neurons after cerebral ischemia.

M3 - Journal article

C2 - 2330128

VL - 109

SP - 247

EP - 252

JO - Neuroscience letters. Supplement

JF - Neuroscience letters. Supplement

SN - 0167-6253

IS - 3

ER -

ID: 5259404