Physical Model for Investigating Intracranial Pressure with Clinical Pressure Sensors and Diagnostic Ultrasound: Preliminary Results

Publikation: Bidrag til bog/antologi/rapportBidrag til bog/antologiForskningfagfællebedømt

  • Rikke von Barm
  • Isabel Martinez Tejada
  • Juhler, Marianne
  • Morten Andresen
  • Jens E. Wilhjelm

Introduction: Intracranial pressure (ICP) is a commonly collected neurocritical parameter, but accurate signal modelling remains challenging. The goal of this project was to mimic clinical ICP waveforms using a physical model. Materials and Methods: A physical head model was developed. The skull was segmented from a head computed tomography (CT) scan, remodelled, 3D-printed, and filled with a brain tissue mimicking material and a pressure generator. Pressure measurements and tissue displacement around an attached pressure sensor were explored. Results: Analysis of the measured pressure demonstrated that the waveform did not perfectly resemble that of the clinical ICP. Through iterative improvements and using a revised second pressure generator, subpeaks could be seen in the waveform. A speckle image recorded using ultrasound during pressure application enabled visualization of tissue displacement around the pressure sensor. Comparison with measured ICP signals revealed that minuscule patterns were not distinct in the displacement images. Discussion: We present the first steps towards mimicking clinical ICP using a physical head phantom model. The physical model enabled pressure tests and visualization of tissue displacement and will be foundational for further improvements.

OriginalsprogEngelsk
TitelActa Neurochirurgica Supplementum
RedaktørerBart Depreitere, Geert Meyfroidt, Fabian Güiza
Antal sider4
Vol/bind131
ForlagSpringer Science and Business Media Deutschland GmbH
Publikationsdato2021
Sider263-266
KapitelVIII
ISBN (Trykt)978-3-030-59435-0
ISBN (Elektronisk)978-3-030-59436-7
DOI
StatusUdgivet - 2021
NavnActa Neurochirurgica, Supplementum
Vol/bind131
ISSN0065-1419

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© 2021, Springer Nature Switzerland AG.

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