Pancreatic tissue fluid pressure in chronic pancreatitis. Relation to pain, morphology, and function.
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Pancreatic tissue fluid pressure in chronic pancreatitis. Relation to pain, morphology, and function. / Ebbehøj, N; Borly, L; Bülow, J; Rasmussen, S G; Madsen, P; Matzen, Peter; Owre, A.
I: Scandinavian Journal of Gastroenterology, Bind 25, Nr. 10, 1990, s. 1046-1051.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning
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T1 - Pancreatic tissue fluid pressure in chronic pancreatitis. Relation to pain, morphology, and function.
AU - Ebbehøj, N
AU - Borly, L
AU - Bülow, J
AU - Rasmussen, S G
AU - Madsen, P
AU - Matzen, Peter
AU - Owre, A
PY - 1990
Y1 - 1990
N2 - The relation between pancreatic tissue fluid pressure and pain, morphology, and function was studied in a cross-sectional investigation. Pressure measurements were performed by percutaneous fine-needle puncture. Thirty-nine patients with chronic pancreatitis were included, 25 with pain and 14 without pain. The pressure was higher in patients with pain than in patients without pain (p = 0.000001), and this was significantly related to a pain score from a visual analogue scale (p less than 0.001). Patients with pancreatic pseudocysts had both higher pressure and higher pain score than patients without (p = 0.004 and p = 0.0003, respectively). The pressure was significantly related (inversely) to pancreatic duct diameter only in the group of 19 patients with earlier pancreatic surgery (R = -0.57, p = 0.02). The pressure was not related to functional factors or the presence of pancreatic calcifications. In conclusion, pancreatic tissue fluid pressure is a valuable indicator of pain in chronic pancreatitis.
AB - The relation between pancreatic tissue fluid pressure and pain, morphology, and function was studied in a cross-sectional investigation. Pressure measurements were performed by percutaneous fine-needle puncture. Thirty-nine patients with chronic pancreatitis were included, 25 with pain and 14 without pain. The pressure was higher in patients with pain than in patients without pain (p = 0.000001), and this was significantly related to a pain score from a visual analogue scale (p less than 0.001). Patients with pancreatic pseudocysts had both higher pressure and higher pain score than patients without (p = 0.004 and p = 0.0003, respectively). The pressure was significantly related (inversely) to pancreatic duct diameter only in the group of 19 patients with earlier pancreatic surgery (R = -0.57, p = 0.02). The pressure was not related to functional factors or the presence of pancreatic calcifications. In conclusion, pancreatic tissue fluid pressure is a valuable indicator of pain in chronic pancreatitis.
M3 - Journal article
VL - 25
SP - 1046
EP - 1051
JO - Scandinavian Journal of Gastroenterology
JF - Scandinavian Journal of Gastroenterology
SN - 0036-5521
IS - 10
ER -
ID: 34189350