Optimizing clinical outcomes for bronchoscopic lung volume reduction with Zephyr® valves
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Optimizing clinical outcomes for bronchoscopic lung volume reduction with Zephyr® valves. / Koster, T. David; Shah, Pallav L.; Valipour, Arschang; Criner, Gerard J.; Herth, Felix J.F.; Sue, Richard; Hogarth, Douglas K.; Martin, Ralitza T.; Mahajan, Amit K.; Alalawi, Raed; Kopas, Lisa; Cohen, Avi; Wood, Douglas E.; Kurman, Jonathan; Shargill, Narinder S.; Dransfield, Mark; Slebos, Dirk Jan; Perch, Michael.
I: Respiratory Medicine, Bind 227, 107639, 2024.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Optimizing clinical outcomes for bronchoscopic lung volume reduction with Zephyr® valves
AU - Koster, T. David
AU - Shah, Pallav L.
AU - Valipour, Arschang
AU - Criner, Gerard J.
AU - Herth, Felix J.F.
AU - Sue, Richard
AU - Hogarth, Douglas K.
AU - Martin, Ralitza T.
AU - Mahajan, Amit K.
AU - Alalawi, Raed
AU - Kopas, Lisa
AU - Cohen, Avi
AU - Wood, Douglas E.
AU - Kurman, Jonathan
AU - Shargill, Narinder S.
AU - Dransfield, Mark
AU - Slebos, Dirk Jan
AU - Perch, Michael
N1 - Publisher Copyright: © 2024 The Authors
PY - 2024
Y1 - 2024
N2 - Bronchoscopic lung volume reduction treatment with Zephyr one-way valves is an effective guideline-based treatment option for patients with severe emphysema and hyperinflation. However, in some cases the treatment response is less than anticipated or there might be a loss of initial treatment effect. Reasons for the lack of response can include incorrect assessment of collateral ventilation, improper valve placement, or patient related factors. Loss of initial benefit can be due to granulation tissue formation and subsequent valve dysfunction, or there may be side effects such as excessive coughing or infectious problems. Careful follow-up after treatment with valves is important and evaluation with a CT scan and/or bronchoscopy is helpful if there is no improvement after treatment or loss of initial benefit. This paper aims to describe the most important causes and provide a strategy of how to approach and manage these patients.
AB - Bronchoscopic lung volume reduction treatment with Zephyr one-way valves is an effective guideline-based treatment option for patients with severe emphysema and hyperinflation. However, in some cases the treatment response is less than anticipated or there might be a loss of initial treatment effect. Reasons for the lack of response can include incorrect assessment of collateral ventilation, improper valve placement, or patient related factors. Loss of initial benefit can be due to granulation tissue formation and subsequent valve dysfunction, or there may be side effects such as excessive coughing or infectious problems. Careful follow-up after treatment with valves is important and evaluation with a CT scan and/or bronchoscopy is helpful if there is no improvement after treatment or loss of initial benefit. This paper aims to describe the most important causes and provide a strategy of how to approach and manage these patients.
KW - Bronchoscopic lung volume reduction
KW - Bronchoscopy
KW - COPD
KW - Endobronchial valves
KW - Granulation tissue
KW - Pneumothorax
U2 - 10.1016/j.rmed.2024.107639
DO - 10.1016/j.rmed.2024.107639
M3 - Review
C2 - 38642906
AN - SCOPUS:85191303806
VL - 227
JO - Respiratory Medicine
JF - Respiratory Medicine
SN - 0954-6111
M1 - 107639
ER -
ID: 391211678