Nocturnal pulse wave amplitude attenuations are associated with long-term cardiovascular events

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Nocturnal pulse wave amplitude attenuations are associated with long-term cardiovascular events. / Shahrbabaki, Sobhan Salari; Linz, Dominik; Baumert, Mathias.

I: International Journal of Cardiology, Bind 385, 2023, s. 55-61.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Shahrbabaki, SS, Linz, D & Baumert, M 2023, 'Nocturnal pulse wave amplitude attenuations are associated with long-term cardiovascular events', International Journal of Cardiology, bind 385, s. 55-61. https://doi.org/10.1016/j.ijcard.2023.05.047

APA

Shahrbabaki, S. S., Linz, D., & Baumert, M. (2023). Nocturnal pulse wave amplitude attenuations are associated with long-term cardiovascular events. International Journal of Cardiology, 385, 55-61. https://doi.org/10.1016/j.ijcard.2023.05.047

Vancouver

Shahrbabaki SS, Linz D, Baumert M. Nocturnal pulse wave amplitude attenuations are associated with long-term cardiovascular events. International Journal of Cardiology. 2023;385:55-61. https://doi.org/10.1016/j.ijcard.2023.05.047

Author

Shahrbabaki, Sobhan Salari ; Linz, Dominik ; Baumert, Mathias. / Nocturnal pulse wave amplitude attenuations are associated with long-term cardiovascular events. I: International Journal of Cardiology. 2023 ; Bind 385. s. 55-61.

Bibtex

@article{ff15cc100d7d40b29bb196c283bbd0f1,

title = "Nocturnal pulse wave amplitude attenuations are associated with long-term cardiovascular events",

abstract = "Objectives: Photoplethysmography (PPG) is an established technology for detecting pulse rate and pulse wave irregularities. However, whether temporal variations in pulse wave amplitudes, reflecting a combination of acute hemodynamic or autonomic responses to changes in overall vascular function, carry prognostic information remains unclear. To quantify nocturnal temporal pulse wave amplitude (PWA) attenuations and evaluate its association with long-term cardiovascular (CV) events in a large, racially diverse sample of men and women. Methods: Temporal PWA attenuations were determined based on the slopes between the upper and lower envelopes of PPGs derived from overnight polysomnography of 1957 participants (899 men, 1058 women, mean age 68.2 ± 9.1 years) of the Multi-Ethnic Study of Atherosclerosis. The nocturnal PWA attenuation index was defined as the cumulative duration of all PWA attenuation events relative to total sleep duration. Results: Nocturnal PWA attenuation index was greater in men than in women by almost 13% (16.3 ± 8.9% vs. 14.4 ± 7.9%, p < 0.001). The nocturnal PWA attenuation index was highest in Chinese-American participants (17.9 ± 9.2%) and lowest in African-Americans (13.5 ± 8.1%). During a median follow-up of 4.9 years, 94 CV events occurred. In multivariable Cox proportional hazard analysis adjusted for typical confounders, the nocturnal PWA attenuation index <15.2% was associated with CV events (HR = 1.58 [1.02–2.45], p = 0.042). Conclusions: Nocturnal PWA attenuation index is inversely associated with the risk of CV events, particularly in men and African-Americans. The PPG-derived nocturnal PWA attenuation index could be simply obtained from smart wearable consumer devices and may provide a low-cost, accessible and scalable CV risk marker.",

keywords = "Cardiovascular disease, Photoplethysmography, Pulse wave, Sleep",

author = "Shahrbabaki, {Sobhan Salari} and Dominik Linz and Mathias Baumert",

note = "Publisher Copyright: {\textcopyright} 2023 The Author(s)",

year = "2023",

doi = "10.1016/j.ijcard.2023.05.047",

language = "English",

volume = "385",

pages = "55--61",

journal = "International Journal of Cardiology",

issn = "0167-5273",

publisher = "Elsevier Ireland Ltd",

}

RIS

TY - JOUR

T1 - Nocturnal pulse wave amplitude attenuations are associated with long-term cardiovascular events

AU - Shahrbabaki, Sobhan Salari

AU - Linz, Dominik

AU - Baumert, Mathias

PY - 2023

Y1 - 2023

N2 - Objectives: Photoplethysmography (PPG) is an established technology for detecting pulse rate and pulse wave irregularities. However, whether temporal variations in pulse wave amplitudes, reflecting a combination of acute hemodynamic or autonomic responses to changes in overall vascular function, carry prognostic information remains unclear. To quantify nocturnal temporal pulse wave amplitude (PWA) attenuations and evaluate its association with long-term cardiovascular (CV) events in a large, racially diverse sample of men and women. Methods: Temporal PWA attenuations were determined based on the slopes between the upper and lower envelopes of PPGs derived from overnight polysomnography of 1957 participants (899 men, 1058 women, mean age 68.2 ± 9.1 years) of the Multi-Ethnic Study of Atherosclerosis. The nocturnal PWA attenuation index was defined as the cumulative duration of all PWA attenuation events relative to total sleep duration. Results: Nocturnal PWA attenuation index was greater in men than in women by almost 13% (16.3 ± 8.9% vs. 14.4 ± 7.9%, p < 0.001). The nocturnal PWA attenuation index was highest in Chinese-American participants (17.9 ± 9.2%) and lowest in African-Americans (13.5 ± 8.1%). During a median follow-up of 4.9 years, 94 CV events occurred. In multivariable Cox proportional hazard analysis adjusted for typical confounders, the nocturnal PWA attenuation index <15.2% was associated with CV events (HR = 1.58 [1.02–2.45], p = 0.042). Conclusions: Nocturnal PWA attenuation index is inversely associated with the risk of CV events, particularly in men and African-Americans. The PPG-derived nocturnal PWA attenuation index could be simply obtained from smart wearable consumer devices and may provide a low-cost, accessible and scalable CV risk marker.

AB - Objectives: Photoplethysmography (PPG) is an established technology for detecting pulse rate and pulse wave irregularities. However, whether temporal variations in pulse wave amplitudes, reflecting a combination of acute hemodynamic or autonomic responses to changes in overall vascular function, carry prognostic information remains unclear. To quantify nocturnal temporal pulse wave amplitude (PWA) attenuations and evaluate its association with long-term cardiovascular (CV) events in a large, racially diverse sample of men and women. Methods: Temporal PWA attenuations were determined based on the slopes between the upper and lower envelopes of PPGs derived from overnight polysomnography of 1957 participants (899 men, 1058 women, mean age 68.2 ± 9.1 years) of the Multi-Ethnic Study of Atherosclerosis. The nocturnal PWA attenuation index was defined as the cumulative duration of all PWA attenuation events relative to total sleep duration. Results: Nocturnal PWA attenuation index was greater in men than in women by almost 13% (16.3 ± 8.9% vs. 14.4 ± 7.9%, p < 0.001). The nocturnal PWA attenuation index was highest in Chinese-American participants (17.9 ± 9.2%) and lowest in African-Americans (13.5 ± 8.1%). During a median follow-up of 4.9 years, 94 CV events occurred. In multivariable Cox proportional hazard analysis adjusted for typical confounders, the nocturnal PWA attenuation index <15.2% was associated with CV events (HR = 1.58 [1.02–2.45], p = 0.042). Conclusions: Nocturnal PWA attenuation index is inversely associated with the risk of CV events, particularly in men and African-Americans. The PPG-derived nocturnal PWA attenuation index could be simply obtained from smart wearable consumer devices and may provide a low-cost, accessible and scalable CV risk marker.

KW - Cardiovascular disease

KW - Photoplethysmography

KW - Pulse wave

KW - Sleep

UR - http://www.scopus.com/inward/record.url?scp=85160783255&partnerID=8YFLogxK

U2 - 10.1016/j.ijcard.2023.05.047

DO - 10.1016/j.ijcard.2023.05.047

M3 - Journal article

C2 - 37257516

AN - SCOPUS:85160783255

VL - 385

SP - 55

EP - 61

JO - International Journal of Cardiology

JF - International Journal of Cardiology

SN - 0167-5273

ER -

ID: 353798365

Biomedicinsk Institut