Metformin protects against lipoapoptosis and enhances GLP-1 secretion from GLP-1-producing cells
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Metformin is the most frequently prescribed drug for treatment of type 2 diabetes. It improves insulin resistance and glycemia by reducing hepatic gluconeogenesis. In addition, diabetic patients on metformin therapy have elevated levels of the insulinotropic hormone glucagon-like peptide-1 (GLP-1) and metformin has been shown to regulate the expression of the GLP-1R in the pancreas.
Originalsprog | Engelsk |
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Tidsskrift | Journal of Gastroenterology |
Vol/bind | 48 |
Udgave nummer | 3 |
Sider (fra-til) | 322-32 |
Antal sider | 11 |
ISSN | 0944-1174 |
DOI | |
Status | Udgivet - mar. 2013 |
ID: 45840439