Influence of age and immunization on development of gingivitis in rats

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Standard

Influence of age and immunization on development of gingivitis in rats. / Lekic, P; Klausen, B; Friis-Hasché, E; Beloica, D; Knezevic, M; Hougen, H P.

I: Acta Odontologica Scandinavica, Bind 47, Nr. 4, 08.1989, s. 233-8.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Lekic, P, Klausen, B, Friis-Hasché, E, Beloica, D, Knezevic, M & Hougen, HP 1989, 'Influence of age and immunization on development of gingivitis in rats', Acta Odontologica Scandinavica, bind 47, nr. 4, s. 233-8.

APA

Lekic, P., Klausen, B., Friis-Hasché, E., Beloica, D., Knezevic, M., & Hougen, H. P. (1989). Influence of age and immunization on development of gingivitis in rats. Acta Odontologica Scandinavica, 47(4), 233-8.

Vancouver

Lekic P, Klausen B, Friis-Hasché E, Beloica D, Knezevic M, Hougen HP. Influence of age and immunization on development of gingivitis in rats. Acta Odontologica Scandinavica. 1989 aug.;47(4):233-8.

Author

Lekic, P ; Klausen, B ; Friis-Hasché, E ; Beloica, D ; Knezevic, M ; Hougen, H P. / Influence of age and immunization on development of gingivitis in rats. I: Acta Odontologica Scandinavica. 1989 ; Bind 47, Nr. 4. s. 233-8.

Bibtex

@article{8f142027c11c4d41a838495a3ed56c47,
title = "Influence of age and immunization on development of gingivitis in rats",
abstract = "To study the effect of age and antigenic priming on the development of gingivitis, 33 healthy rats were placed in contact with Streptococcus mutans, Actinomyces viscosus, Fusobacterium nucleatum, and Bacteroides gingivalis. On days 0, 3, 7, and 14 after inoculation, the gingival condition was judged clinically and histologically, and serum antibody titers against the bacteria were measured. The rats were divided into three groups: 1 month old, 3 months old, and 3 months old immunized. None of the young rats developed gingivitis during the experiment, whereas half of the adult and all of the adult immunized rats bled on probing on days 7 and 14. In general, antibody titers against the bacteria were low in young rats, moderate in adult rats, and high in adult immunized rats. These results indicate that adult rats react stronger to plaque antigens than young rats and that previous contact with the antigens increases the reaction.",
keywords = "Actinomyces, Aging, Animals, Antibodies, Bacterial, Antigens, Bacterial, Bacteroides, Female, Fusobacterium, Gingiva, Gingivitis, Immunization, Leukocyte Count, Male, Rats, Rats, Inbred Lew, Rats, Inbred Strains, Streptococcus mutans",
author = "P Lekic and B Klausen and E Friis-Hasch{\'e} and D Beloica and M Knezevic and Hougen, {H P}",
year = "1989",
month = aug,
language = "English",
volume = "47",
pages = "233--8",
journal = "Acta Odontologica Scandinavica",
issn = "0001-6357",
publisher = "Taylor & Francis",
number = "4",

}

RIS

TY - JOUR

T1 - Influence of age and immunization on development of gingivitis in rats

AU - Lekic, P

AU - Klausen, B

AU - Friis-Hasché, E

AU - Beloica, D

AU - Knezevic, M

AU - Hougen, H P

PY - 1989/8

Y1 - 1989/8

N2 - To study the effect of age and antigenic priming on the development of gingivitis, 33 healthy rats were placed in contact with Streptococcus mutans, Actinomyces viscosus, Fusobacterium nucleatum, and Bacteroides gingivalis. On days 0, 3, 7, and 14 after inoculation, the gingival condition was judged clinically and histologically, and serum antibody titers against the bacteria were measured. The rats were divided into three groups: 1 month old, 3 months old, and 3 months old immunized. None of the young rats developed gingivitis during the experiment, whereas half of the adult and all of the adult immunized rats bled on probing on days 7 and 14. In general, antibody titers against the bacteria were low in young rats, moderate in adult rats, and high in adult immunized rats. These results indicate that adult rats react stronger to plaque antigens than young rats and that previous contact with the antigens increases the reaction.

AB - To study the effect of age and antigenic priming on the development of gingivitis, 33 healthy rats were placed in contact with Streptococcus mutans, Actinomyces viscosus, Fusobacterium nucleatum, and Bacteroides gingivalis. On days 0, 3, 7, and 14 after inoculation, the gingival condition was judged clinically and histologically, and serum antibody titers against the bacteria were measured. The rats were divided into three groups: 1 month old, 3 months old, and 3 months old immunized. None of the young rats developed gingivitis during the experiment, whereas half of the adult and all of the adult immunized rats bled on probing on days 7 and 14. In general, antibody titers against the bacteria were low in young rats, moderate in adult rats, and high in adult immunized rats. These results indicate that adult rats react stronger to plaque antigens than young rats and that previous contact with the antigens increases the reaction.

KW - Actinomyces

KW - Aging

KW - Animals

KW - Antibodies, Bacterial

KW - Antigens, Bacterial

KW - Bacteroides

KW - Female

KW - Fusobacterium

KW - Gingiva

KW - Gingivitis

KW - Immunization

KW - Leukocyte Count

KW - Male

KW - Rats

KW - Rats, Inbred Lew

KW - Rats, Inbred Strains

KW - Streptococcus mutans

M3 - Journal article

C2 - 2789463

VL - 47

SP - 233

EP - 238

JO - Acta Odontologica Scandinavica

JF - Acta Odontologica Scandinavica

SN - 0001-6357

IS - 4

ER -

ID: 44514766