Immunoassays of human trefoil factors 1 and 2: measured on serum from patients with inflammatory bowel disease
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Immunoassays of human trefoil factors 1 and 2 : measured on serum from patients with inflammatory bowel disease. / Vestergaard, E M; Brynskov, J; Ejskjaer, K; Clausen, J T; Thim, L; Nexø, Ebba; Poulsen, Steen Seier.
I: Scandinavian Journal of Clinical & Laboratory Investigation, Bind 64, Nr. 2, 04.2004, s. 146-56.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Immunoassays of human trefoil factors 1 and 2
T2 - measured on serum from patients with inflammatory bowel disease
AU - Vestergaard, E M
AU - Brynskov, J
AU - Ejskjaer, K
AU - Clausen, J T
AU - Thim, L
AU - Nexø, Ebba
AU - Poulsen, Steen Seier
PY - 2004/4
Y1 - 2004/4
N2 - The trefoil factors (TFF1-3) are cysteine-rich peptides expressed in the gastrointestinal tract where they play a critical role in mucosal protection and repair. The expression is up-regulated at sites of ulceration in various chronic inflammatory diseases. Recently, we presented an ELISA method for measurement of TFF3. The aims of the present study were to develop and evaluate ELISAs for the other two known human trefoil peptides, TFF1 and TFF2, and to carry out a cross-sectional study on serum TFF levels in patients with inflammatory bowel disease (IBD).
AB - The trefoil factors (TFF1-3) are cysteine-rich peptides expressed in the gastrointestinal tract where they play a critical role in mucosal protection and repair. The expression is up-regulated at sites of ulceration in various chronic inflammatory diseases. Recently, we presented an ELISA method for measurement of TFF3. The aims of the present study were to develop and evaluate ELISAs for the other two known human trefoil peptides, TFF1 and TFF2, and to carry out a cross-sectional study on serum TFF levels in patients with inflammatory bowel disease (IBD).
KW - Adolescent
KW - Adult
KW - Aged
KW - Aging
KW - Enzyme-Linked Immunosorbent Assay
KW - Female
KW - Health
KW - Humans
KW - Immunoassay
KW - Inflammatory Bowel Diseases
KW - Male
KW - Middle Aged
KW - Mucins
KW - Muscle Proteins
KW - Peptides
KW - Proteins
KW - Sensitivity and Specificity
KW - Tumor Suppressor Proteins
M3 - Journal article
C2 - 15115253
VL - 64
SP - 146
EP - 156
JO - Scandinavian Journal of Clinical & Laboratory Investigation
JF - Scandinavian Journal of Clinical & Laboratory Investigation
SN - 0036-5513
IS - 2
ER -
ID: 47486205