Histomorphometrical analysis of the influence of soft diet on masticatory muscle development in the muscular dystrophic mouse
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Histomorphometrical analysis of the influence of soft diet on masticatory muscle development in the muscular dystrophic mouse. / Vilmann, H; Kirkeby, S; Kronborg, D.
I: Archives of Oral Biology, Bind 35, Nr. 1, 1990, s. 37-42.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Histomorphometrical analysis of the influence of soft diet on masticatory muscle development in the muscular dystrophic mouse
AU - Vilmann, H
AU - Kirkeby, S
AU - Kronborg, D
N1 - Keywords: Animals; Body Weight; Diet; Facial Muscles; Female; Food; Masseter Muscle; Mastication; Masticatory Muscles; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Muscular Dystrophy, Animal; Myofibrils; Neck Muscles
PY - 1990
Y1 - 1990
N2 - The known difference in the severity of dystrophy between the masseter and the digastric muscle of the mouse (dy/dy C57BL/J6) may be attributed to the differences in muscle work load. This possibility was tested by subjecting 3-week-old mice (normal and dystrophic) to a soft diet for 4 weeks. Microscopic examination of haematoxylin-eosin stained sections of these muscles showed that the fibre size dispersion (a measure of disease severity) decreased slightly but significantly in the masseters of mice on a soft diet. It was thus possible to improve the condition of dystrophic masticatory muscles by changing their function. Body weight curves measured during the experimental period suggest that the dystrophic mice may have been under weight because of malnutrition due to lack of sufficient masticatory power.
AB - The known difference in the severity of dystrophy between the masseter and the digastric muscle of the mouse (dy/dy C57BL/J6) may be attributed to the differences in muscle work load. This possibility was tested by subjecting 3-week-old mice (normal and dystrophic) to a soft diet for 4 weeks. Microscopic examination of haematoxylin-eosin stained sections of these muscles showed that the fibre size dispersion (a measure of disease severity) decreased slightly but significantly in the masseters of mice on a soft diet. It was thus possible to improve the condition of dystrophic masticatory muscles by changing their function. Body weight curves measured during the experimental period suggest that the dystrophic mice may have been under weight because of malnutrition due to lack of sufficient masticatory power.
M3 - Journal article
C2 - 2390022
VL - 35
SP - 37
EP - 42
JO - Archives of Oral Biology
JF - Archives of Oral Biology
SN - 0003-9969
IS - 1
ER -
ID: 10141219