Focal pulsed field electroporation of left ventricular premature contractions after failed radiofrequency ablation
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Focal pulsed field electroporation of left ventricular premature contractions after failed radiofrequency ablation. / Hansen, Jim; Haugdal, Martin A.; Johannessen, Arne; Hansen, Morten Lock; Worck, Rene; Ruwald, Martin H.
I: HeartRhythm Case Reports, Bind 9, Nr. 8, 2023.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Focal pulsed field electroporation of left ventricular premature contractions after failed radiofrequency ablation
AU - Hansen, Jim
AU - Haugdal, Martin A.
AU - Johannessen, Arne
AU - Hansen, Morten Lock
AU - Worck, Rene
AU - Ruwald, Martin H.
N1 - Funding Information: None. RW has received research grants and speaker honoraria from Biosense Webster and JH has received research grants and speaker honoraria from Medtronic, Biosense Webster, and Boston Scientific. All other authors have no disclosures or conflicts of interest.
PY - 2023
Y1 - 2023
N2 - Pulsed field electroporation (PFE) has earned substantial attention owing to its unique, non–thermal tissue–preferential mechanism for cardiac ablation of arrhythmias and is used increasingly for pulmonary vein isolation.1, 2, 3 Recently, a pulsed electrical field delivery system consisting of a proprietary generator coupled to specified ablation catheters and 3D electroanatomical mapping systems obtained CE approval for pulmonary vein isolation in patients with paroxysmal atrial fibrillation based on results of the ECLIPSE trial.4 The utility of this system for mapping and ablation in human ventricular myocardium in the clinical setting of ventricular arrhythmias was recently reported in case form.5 In this case we present the first successful use of PFE for focal endocardial ablation of premature contractions from the left ventricle following extensive unsuccessful attempts at radiofrequency ablation (RFA) in the same procedure. Thus, in a direct intraprocedural comparison, focal PFE was superior to RFA, indicating a promising role for this ablation modality in the future treatment of ventricular arrhythmias.
AB - Pulsed field electroporation (PFE) has earned substantial attention owing to its unique, non–thermal tissue–preferential mechanism for cardiac ablation of arrhythmias and is used increasingly for pulmonary vein isolation.1, 2, 3 Recently, a pulsed electrical field delivery system consisting of a proprietary generator coupled to specified ablation catheters and 3D electroanatomical mapping systems obtained CE approval for pulmonary vein isolation in patients with paroxysmal atrial fibrillation based on results of the ECLIPSE trial.4 The utility of this system for mapping and ablation in human ventricular myocardium in the clinical setting of ventricular arrhythmias was recently reported in case form.5 In this case we present the first successful use of PFE for focal endocardial ablation of premature contractions from the left ventricle following extensive unsuccessful attempts at radiofrequency ablation (RFA) in the same procedure. Thus, in a direct intraprocedural comparison, focal PFE was superior to RFA, indicating a promising role for this ablation modality in the future treatment of ventricular arrhythmias.
KW - 3D mapping
KW - Electrogram
KW - Electroporation
KW - Premature ventricular contractions
KW - Pulsed field ablation
KW - Ventricular arrhythmia
U2 - 10.1016/j.hrcr.2023.05.019
DO - 10.1016/j.hrcr.2023.05.019
M3 - Journal article
C2 - 37614400
AN - SCOPUS:85163371334
VL - 9
JO - HeartRhythm Case Reports
JF - HeartRhythm Case Reports
SN - 2214-0271
IS - 8
ER -
ID: 366388620