Epidermal growth factor in rat milk is dependent on insulin

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Standard

Epidermal growth factor in rat milk is dependent on insulin. / Thulesen, J; Poulsen, Steen Seier; Nexo, E; Raaberg, Lasse.

I: Endocrine Regulations, Bind 27, Nr. 3, 09.1993, s. 139-44.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Thulesen, J, Poulsen, SS, Nexo, E & Raaberg, L 1993, 'Epidermal growth factor in rat milk is dependent on insulin', Endocrine Regulations, bind 27, nr. 3, s. 139-44.

APA

Thulesen, J., Poulsen, S. S., Nexo, E., & Raaberg, L. (1993). Epidermal growth factor in rat milk is dependent on insulin. Endocrine Regulations, 27(3), 139-44.

Vancouver

Thulesen J, Poulsen SS, Nexo E, Raaberg L. Epidermal growth factor in rat milk is dependent on insulin. Endocrine Regulations. 1993 sep.;27(3):139-44.

Author

Thulesen, J ; Poulsen, Steen Seier ; Nexo, E ; Raaberg, Lasse. / Epidermal growth factor in rat milk is dependent on insulin. I: Endocrine Regulations. 1993 ; Bind 27, Nr. 3. s. 139-44.

Bibtex

@article{89be00c3064c4da7a7a4904f56f861fe,
title = "Epidermal growth factor in rat milk is dependent on insulin",
abstract = "Epidermal growth factor (EGF) was measured in milk from four groups of rats: untreated diabetic, insulin-treated diabetic, insulin-treated normal and control rats. In the untreated diabetic group the volume of milk, and the concentration of EGF and the total output of EGF were significantly decreased when compared to the control group. In contrast, the total protein concentration in milk from the untreated diabetic rats was similar to the concentration in milk from the control rats. Insulin-treatment of diabetic rats almost completely reversed the decrease in the milk volume and in the concentration of EGF, and thus normalized the total output of EGF. The insulin-treated normal rats which remained euglycemic had a significantly increased concentration of EGF and of total protein without any difference in the volume of milk when compared to the controls. The results indicate that the secretion of EGF from the mammary glands is dependent on insulin and that the decrement in milk-EGF from diabetic rats is selective when compared to the content of protein in milk.",
keywords = "Animals, Diabetes Mellitus, Experimental, Epidermal Growth Factor, Female, Insulin, Lactation, Milk, Rats, Rats, Wistar",
author = "J Thulesen and Poulsen, {Steen Seier} and E Nexo and Lasse Raaberg",
year = "1993",
month = sep,
language = "English",
volume = "27",
pages = "139--44",
journal = "Endocrine Regulations",
issn = "1210-0668",
publisher = "AEPress, s.r.o",
number = "3",

}

RIS

TY - JOUR

T1 - Epidermal growth factor in rat milk is dependent on insulin

AU - Thulesen, J

AU - Poulsen, Steen Seier

AU - Nexo, E

AU - Raaberg, Lasse

PY - 1993/9

Y1 - 1993/9

N2 - Epidermal growth factor (EGF) was measured in milk from four groups of rats: untreated diabetic, insulin-treated diabetic, insulin-treated normal and control rats. In the untreated diabetic group the volume of milk, and the concentration of EGF and the total output of EGF were significantly decreased when compared to the control group. In contrast, the total protein concentration in milk from the untreated diabetic rats was similar to the concentration in milk from the control rats. Insulin-treatment of diabetic rats almost completely reversed the decrease in the milk volume and in the concentration of EGF, and thus normalized the total output of EGF. The insulin-treated normal rats which remained euglycemic had a significantly increased concentration of EGF and of total protein without any difference in the volume of milk when compared to the controls. The results indicate that the secretion of EGF from the mammary glands is dependent on insulin and that the decrement in milk-EGF from diabetic rats is selective when compared to the content of protein in milk.

AB - Epidermal growth factor (EGF) was measured in milk from four groups of rats: untreated diabetic, insulin-treated diabetic, insulin-treated normal and control rats. In the untreated diabetic group the volume of milk, and the concentration of EGF and the total output of EGF were significantly decreased when compared to the control group. In contrast, the total protein concentration in milk from the untreated diabetic rats was similar to the concentration in milk from the control rats. Insulin-treatment of diabetic rats almost completely reversed the decrease in the milk volume and in the concentration of EGF, and thus normalized the total output of EGF. The insulin-treated normal rats which remained euglycemic had a significantly increased concentration of EGF and of total protein without any difference in the volume of milk when compared to the controls. The results indicate that the secretion of EGF from the mammary glands is dependent on insulin and that the decrement in milk-EGF from diabetic rats is selective when compared to the content of protein in milk.

KW - Animals

KW - Diabetes Mellitus, Experimental

KW - Epidermal Growth Factor

KW - Female

KW - Insulin

KW - Lactation

KW - Milk

KW - Rats

KW - Rats, Wistar

M3 - Journal article

C2 - 8193313

VL - 27

SP - 139

EP - 144

JO - Endocrine Regulations

JF - Endocrine Regulations

SN - 1210-0668

IS - 3

ER -

ID: 47487434