EMLA for pain relief during arterial cannulation. A double-blind, placebo-controlled study of a lidocaine-prilocaine cream

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Standard

EMLA for pain relief during arterial cannulation. A double-blind, placebo-controlled study of a lidocaine-prilocaine cream. / Nilsson, A; Danielson, K; Engberg, G; Henneberg, S.

I: Upsala Journal of Medical Sciences, Bind 95, Nr. 1, 01.01.1990, s. 87-94.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Nilsson, A, Danielson, K, Engberg, G & Henneberg, S 1990, 'EMLA for pain relief during arterial cannulation. A double-blind, placebo-controlled study of a lidocaine-prilocaine cream', Upsala Journal of Medical Sciences, bind 95, nr. 1, s. 87-94.

APA

Nilsson, A., Danielson, K., Engberg, G., & Henneberg, S. (1990). EMLA for pain relief during arterial cannulation. A double-blind, placebo-controlled study of a lidocaine-prilocaine cream. Upsala Journal of Medical Sciences, 95(1), 87-94.

Vancouver

Nilsson A, Danielson K, Engberg G, Henneberg S. EMLA for pain relief during arterial cannulation. A double-blind, placebo-controlled study of a lidocaine-prilocaine cream. Upsala Journal of Medical Sciences. 1990 jan. 1;95(1):87-94.

Author

Nilsson, A ; Danielson, K ; Engberg, G ; Henneberg, S. / EMLA for pain relief during arterial cannulation. A double-blind, placebo-controlled study of a lidocaine-prilocaine cream. I: Upsala Journal of Medical Sciences. 1990 ; Bind 95, Nr. 1. s. 87-94.

Bibtex

@article{8e8f3a918ba0456b8b8fc96c9f1e39db,
title = "EMLA for pain relief during arterial cannulation. A double-blind, placebo-controlled study of a lidocaine-prilocaine cream",
abstract = "The aim of the study was to evaluate the effect of a lidocaine-prilocaine cream (EMLA cream, Astra) in relieving pain during arterial cannulation. The study had a random, double-blind, placebo-controlled design and included altogether 90 patients. All the patients were premedicated with an opioid before cannulation. An EMLA application time of 60 minutes was used in 60 patients (30 EMLA/30 placebo) and there was no difference in the pain reaction measured on a visual analogue scale (VAS) or on an observer's verbal scale. The study was extended with a further 30 patients (15 EMLA/15 placebo) with an application time exceeding 90 minutes. Between these groups pain experience measured by VAS did not show any significant difference although the mean value was lower in the EMLA group. Observer ratings showed a significant (p less than 0.01) difference in distribution towards lower ratings in the EMLA group. In conclusion EMLA was found to have a weak, but measurable effect when the application time exceeded 90 minutes but not after 60 minutes.",
author = "A Nilsson and K Danielson and G Engberg and S Henneberg",
year = "1990",
month = jan,
day = "1",
language = "English",
volume = "95",
pages = "87--94",
journal = "Upsala l{\"a}karef{\"o}renings f{\"o}rhandlingar",
issn = "0300-9726",
publisher = "Taylor & Francis",
number = "1",

}

RIS

TY - JOUR

T1 - EMLA for pain relief during arterial cannulation. A double-blind, placebo-controlled study of a lidocaine-prilocaine cream

AU - Nilsson, A

AU - Danielson, K

AU - Engberg, G

AU - Henneberg, S

PY - 1990/1/1

Y1 - 1990/1/1

N2 - The aim of the study was to evaluate the effect of a lidocaine-prilocaine cream (EMLA cream, Astra) in relieving pain during arterial cannulation. The study had a random, double-blind, placebo-controlled design and included altogether 90 patients. All the patients were premedicated with an opioid before cannulation. An EMLA application time of 60 minutes was used in 60 patients (30 EMLA/30 placebo) and there was no difference in the pain reaction measured on a visual analogue scale (VAS) or on an observer's verbal scale. The study was extended with a further 30 patients (15 EMLA/15 placebo) with an application time exceeding 90 minutes. Between these groups pain experience measured by VAS did not show any significant difference although the mean value was lower in the EMLA group. Observer ratings showed a significant (p less than 0.01) difference in distribution towards lower ratings in the EMLA group. In conclusion EMLA was found to have a weak, but measurable effect when the application time exceeded 90 minutes but not after 60 minutes.

AB - The aim of the study was to evaluate the effect of a lidocaine-prilocaine cream (EMLA cream, Astra) in relieving pain during arterial cannulation. The study had a random, double-blind, placebo-controlled design and included altogether 90 patients. All the patients were premedicated with an opioid before cannulation. An EMLA application time of 60 minutes was used in 60 patients (30 EMLA/30 placebo) and there was no difference in the pain reaction measured on a visual analogue scale (VAS) or on an observer's verbal scale. The study was extended with a further 30 patients (15 EMLA/15 placebo) with an application time exceeding 90 minutes. Between these groups pain experience measured by VAS did not show any significant difference although the mean value was lower in the EMLA group. Observer ratings showed a significant (p less than 0.01) difference in distribution towards lower ratings in the EMLA group. In conclusion EMLA was found to have a weak, but measurable effect when the application time exceeded 90 minutes but not after 60 minutes.

M3 - Journal article

VL - 95

SP - 87

EP - 94

JO - Upsala läkareförenings förhandlingar

JF - Upsala läkareförenings förhandlingar

SN - 0300-9726

IS - 1

ER -

ID: 34100178