Decreased susceptibility to zinc chloride is associated with methicillin resistant Staphylococcus aureus CC398 in Danish swine

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Standard

Decreased susceptibility to zinc chloride is associated with methicillin resistant Staphylococcus aureus CC398 in Danish swine. / Aarestrup, Frank Møller; Cavaco, Lina; Hasman, Henrik.

I: Veterinary Microbiology, Bind 142, Nr. 3-4, 19.05.2010, s. 455-7.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Aarestrup, FM, Cavaco, L & Hasman, H 2010, 'Decreased susceptibility to zinc chloride is associated with methicillin resistant Staphylococcus aureus CC398 in Danish swine', Veterinary Microbiology, bind 142, nr. 3-4, s. 455-7. https://doi.org/10.1016/j.vetmic.2009.10.021

APA

Aarestrup, F. M., Cavaco, L., & Hasman, H. (2010). Decreased susceptibility to zinc chloride is associated with methicillin resistant Staphylococcus aureus CC398 in Danish swine. Veterinary Microbiology, 142(3-4), 455-7. https://doi.org/10.1016/j.vetmic.2009.10.021

Vancouver

Aarestrup FM, Cavaco L, Hasman H. Decreased susceptibility to zinc chloride is associated with methicillin resistant Staphylococcus aureus CC398 in Danish swine. Veterinary Microbiology. 2010 maj 19;142(3-4):455-7. https://doi.org/10.1016/j.vetmic.2009.10.021

Author

Aarestrup, Frank Møller ; Cavaco, Lina ; Hasman, Henrik. / Decreased susceptibility to zinc chloride is associated with methicillin resistant Staphylococcus aureus CC398 in Danish swine. I: Veterinary Microbiology. 2010 ; Bind 142, Nr. 3-4. s. 455-7.

Bibtex

@article{4fa9465bf26345488dfbe3e03f1f1e68,
title = "Decreased susceptibility to zinc chloride is associated with methicillin resistant Staphylococcus aureus CC398 in Danish swine",
abstract = "A total of 31 MRSA and 60 MSSA isolated from different swine farms in Denmark were examined for their susceptibility to zinc chloride, erythromycin, penicillin and tetracycline, as well as their spa-type. mecA positive isolates were examined for their SCCmec type. The isolates were assigned to a CC-type based on their spa-type and supportive multi-locus sequence typing (MLST). No difference in susceptibility to erythromycin, penicillin or tetracycline could be observed between methicillin resistant and susceptible isolates of CC398. Twenty-three (74%) of the MRSA CC398 isolates had reduced susceptibility to ZnCl(2) (MIC 4-12 mM), whereas all MSSA had MICs from 0.5 to 2 mM. Thirty MRSA, including all 23 zinc resistant isolates harboured SCCmec type V. This provides biological evidence to suggest that the use of zinc compounds may be partly implicated in the emergence of some MRSA clones among swine in Denmark.",
keywords = "Animals, Anti-Bacterial Agents, Chlorides, Denmark, Methicillin-Resistant Staphylococcus aureus, Microbial Sensitivity Tests, Staphylococcal Infections, Swine, Swine Diseases, Zinc Compounds, Journal Article, Research Support, Non-U.S. Gov't",
author = "Aarestrup, {Frank M{\o}ller} and Lina Cavaco and Henrik Hasman",
note = "Copyright 2009 Elsevier B.V. All rights reserved.",
year = "2010",
month = may,
day = "19",
doi = "10.1016/j.vetmic.2009.10.021",
language = "English",
volume = "142",
pages = "455--7",
journal = "Veterinary Microbiology",
issn = "0378-1135",
publisher = "Elsevier",
number = "3-4",

}

RIS

TY - JOUR

T1 - Decreased susceptibility to zinc chloride is associated with methicillin resistant Staphylococcus aureus CC398 in Danish swine

AU - Aarestrup, Frank Møller

AU - Cavaco, Lina

AU - Hasman, Henrik

N1 - Copyright 2009 Elsevier B.V. All rights reserved.

PY - 2010/5/19

Y1 - 2010/5/19

N2 - A total of 31 MRSA and 60 MSSA isolated from different swine farms in Denmark were examined for their susceptibility to zinc chloride, erythromycin, penicillin and tetracycline, as well as their spa-type. mecA positive isolates were examined for their SCCmec type. The isolates were assigned to a CC-type based on their spa-type and supportive multi-locus sequence typing (MLST). No difference in susceptibility to erythromycin, penicillin or tetracycline could be observed between methicillin resistant and susceptible isolates of CC398. Twenty-three (74%) of the MRSA CC398 isolates had reduced susceptibility to ZnCl(2) (MIC 4-12 mM), whereas all MSSA had MICs from 0.5 to 2 mM. Thirty MRSA, including all 23 zinc resistant isolates harboured SCCmec type V. This provides biological evidence to suggest that the use of zinc compounds may be partly implicated in the emergence of some MRSA clones among swine in Denmark.

AB - A total of 31 MRSA and 60 MSSA isolated from different swine farms in Denmark were examined for their susceptibility to zinc chloride, erythromycin, penicillin and tetracycline, as well as their spa-type. mecA positive isolates were examined for their SCCmec type. The isolates were assigned to a CC-type based on their spa-type and supportive multi-locus sequence typing (MLST). No difference in susceptibility to erythromycin, penicillin or tetracycline could be observed between methicillin resistant and susceptible isolates of CC398. Twenty-three (74%) of the MRSA CC398 isolates had reduced susceptibility to ZnCl(2) (MIC 4-12 mM), whereas all MSSA had MICs from 0.5 to 2 mM. Thirty MRSA, including all 23 zinc resistant isolates harboured SCCmec type V. This provides biological evidence to suggest that the use of zinc compounds may be partly implicated in the emergence of some MRSA clones among swine in Denmark.

KW - Animals

KW - Anti-Bacterial Agents

KW - Chlorides

KW - Denmark

KW - Methicillin-Resistant Staphylococcus aureus

KW - Microbial Sensitivity Tests

KW - Staphylococcal Infections

KW - Swine

KW - Swine Diseases

KW - Zinc Compounds

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

U2 - 10.1016/j.vetmic.2009.10.021

DO - 10.1016/j.vetmic.2009.10.021

M3 - Journal article

C2 - 19939591

VL - 142

SP - 455

EP - 457

JO - Veterinary Microbiology

JF - Veterinary Microbiology

SN - 0378-1135

IS - 3-4

ER -

ID: 183246616