Decreased blood platelet volume and count in patients with liver disease

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Decreased blood platelet volume and count in patients with liver disease. / Jørgensen, B; Fischer, E; Ingeberg, S; Hollaender, N; Ring-Larsen, H; Henriksen, Jens Henrik Sahl.

I: Scandinavian Journal of Gastroenterology, Bind 19, Nr. 4, 1984, s. 492-6.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Jørgensen, B, Fischer, E, Ingeberg, S, Hollaender, N, Ring-Larsen, H & Henriksen, JHS 1984, 'Decreased blood platelet volume and count in patients with liver disease', Scandinavian Journal of Gastroenterology, bind 19, nr. 4, s. 492-6.

APA

Jørgensen, B., Fischer, E., Ingeberg, S., Hollaender, N., Ring-Larsen, H., & Henriksen, J. H. S. (1984). Decreased blood platelet volume and count in patients with liver disease. Scandinavian Journal of Gastroenterology, 19(4), 492-6.

Vancouver

Jørgensen B, Fischer E, Ingeberg S, Hollaender N, Ring-Larsen H, Henriksen JHS. Decreased blood platelet volume and count in patients with liver disease. Scandinavian Journal of Gastroenterology. 1984;19(4):492-6.

Author

Jørgensen, B ; Fischer, E ; Ingeberg, S ; Hollaender, N ; Ring-Larsen, H ; Henriksen, Jens Henrik Sahl. / Decreased blood platelet volume and count in patients with liver disease. I: Scandinavian Journal of Gastroenterology. 1984 ; Bind 19, Nr. 4. s. 492-6.

Bibtex

@article{15ec93404b8a11df928f000ea68e967b,
title = "Decreased blood platelet volume and count in patients with liver disease",
abstract = "Mean platelet volume (MPV) and count (PLT) were assessed in patients with moderately affected liver function. PLT was significantly decreased in patients with liver disease (197 X 10(9)l-1 +/- 87 (SD), no. = 79) compared with that of controls (273 X 10(9)l-1 +/- 53 (SD), no. = 37, P less than 0.001). MPV in patients with liver disease (9.25 +/- 1.14 fl) was significantly lower than that of controls (10.52 +/-0.74 fl, P less than 0.001). In control subjects MPV and PLT were inversely correlated (r = -0.48, P less than 0.01), but statistical significance was not found in patients with liver disease (r = -0.2, 0.05 less than P less than 0.1). It is concluded that the low MPV and PLT are compatible with an intravascular activation (loss of granules) and increased consumption of platelets, which may take place in the diseased liver even in patients with a relatively well preserved liver function.",
author = "B J{\o}rgensen and E Fischer and S Ingeberg and N Hollaender and H Ring-Larsen and Henriksen, {Jens Henrik Sahl}",
note = "Keywords: Adult; Aged; Blood Platelets; Blood Volume; Female; Hepatitis, Viral, Human; Humans; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Platelet Count",
year = "1984",
language = "English",
volume = "19",
pages = "492--6",
journal = "Scandinavian Journal of Gastroenterology",
issn = "0036-5521",
publisher = "Taylor & Francis",
number = "4",

}

RIS

TY - JOUR

T1 - Decreased blood platelet volume and count in patients with liver disease

AU - Jørgensen, B

AU - Fischer, E

AU - Ingeberg, S

AU - Hollaender, N

AU - Ring-Larsen, H

AU - Henriksen, Jens Henrik Sahl

N1 - Keywords: Adult; Aged; Blood Platelets; Blood Volume; Female; Hepatitis, Viral, Human; Humans; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Platelet Count

PY - 1984

Y1 - 1984

N2 - Mean platelet volume (MPV) and count (PLT) were assessed in patients with moderately affected liver function. PLT was significantly decreased in patients with liver disease (197 X 10(9)l-1 +/- 87 (SD), no. = 79) compared with that of controls (273 X 10(9)l-1 +/- 53 (SD), no. = 37, P less than 0.001). MPV in patients with liver disease (9.25 +/- 1.14 fl) was significantly lower than that of controls (10.52 +/-0.74 fl, P less than 0.001). In control subjects MPV and PLT were inversely correlated (r = -0.48, P less than 0.01), but statistical significance was not found in patients with liver disease (r = -0.2, 0.05 less than P less than 0.1). It is concluded that the low MPV and PLT are compatible with an intravascular activation (loss of granules) and increased consumption of platelets, which may take place in the diseased liver even in patients with a relatively well preserved liver function.

AB - Mean platelet volume (MPV) and count (PLT) were assessed in patients with moderately affected liver function. PLT was significantly decreased in patients with liver disease (197 X 10(9)l-1 +/- 87 (SD), no. = 79) compared with that of controls (273 X 10(9)l-1 +/- 53 (SD), no. = 37, P less than 0.001). MPV in patients with liver disease (9.25 +/- 1.14 fl) was significantly lower than that of controls (10.52 +/-0.74 fl, P less than 0.001). In control subjects MPV and PLT were inversely correlated (r = -0.48, P less than 0.01), but statistical significance was not found in patients with liver disease (r = -0.2, 0.05 less than P less than 0.1). It is concluded that the low MPV and PLT are compatible with an intravascular activation (loss of granules) and increased consumption of platelets, which may take place in the diseased liver even in patients with a relatively well preserved liver function.

M3 - Journal article

C2 - 6463571

VL - 19

SP - 492

EP - 496

JO - Scandinavian Journal of Gastroenterology

JF - Scandinavian Journal of Gastroenterology

SN - 0036-5521

IS - 4

ER -

ID: 19345032