Cloning of the pig aminopeptidase N gene. Identification of possible regulatory elements and the exon distribution in relation to the membrane-spanning region.

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Standard

Cloning of the pig aminopeptidase N gene. Identification of possible regulatory elements and the exon distribution in relation to the membrane-spanning region. / Sjöström, H; Norén, O; Olsen, Jørgen.

I: FEBS Letters, Bind 251, Nr. 1-2, 1989, s. 275-81.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Sjöström, H, Norén, O & Olsen, J 1989, 'Cloning of the pig aminopeptidase N gene. Identification of possible regulatory elements and the exon distribution in relation to the membrane-spanning region.', FEBS Letters, bind 251, nr. 1-2, s. 275-81.

APA

Sjöström, H., Norén, O., & Olsen, J. (1989). Cloning of the pig aminopeptidase N gene. Identification of possible regulatory elements and the exon distribution in relation to the membrane-spanning region. FEBS Letters, 251(1-2), 275-81.

Vancouver

Sjöström H, Norén O, Olsen J. Cloning of the pig aminopeptidase N gene. Identification of possible regulatory elements and the exon distribution in relation to the membrane-spanning region. FEBS Letters. 1989;251(1-2):275-81.

Author

Sjöström, H ; Norén, O ; Olsen, Jørgen. / Cloning of the pig aminopeptidase N gene. Identification of possible regulatory elements and the exon distribution in relation to the membrane-spanning region. I: FEBS Letters. 1989 ; Bind 251, Nr. 1-2. s. 275-81.

Bibtex

@article{8bad4dc099f911dd86a6000ea68e967b,
title = "Cloning of the pig aminopeptidase N gene. Identification of possible regulatory elements and the exon distribution in relation to the membrane-spanning region.",
abstract = "We have isolated four lambda-phages covering the complete pig aminopeptidase N/CD13 gene. The sequence of 2.85 kbp encompasses 1.18 kbp of the 5' upstream region and 1.67 kbp of the structural gene. In the promoter region we find a TATA box and potential binding sites for CTF-1/NF-1 and AP-2. By sequence comparisons we have found three domains showing similarity to promoter regions of the genes encoding human alpha 1-antitrypsin and human intestinal alkaline phosphatase. The gene sequence includes the first three exons and two introns. It shows that a single exon encodes the cytoplasmic tail, the membrane anchor and the junctional peptide.",
author = "H Sj{\"o}str{\"o}m and O Nor{\'e}n and J{\o}rgen Olsen",
note = "Keywords: Alkaline Phosphatase; Amino Acid Sequence; Aminopeptidases; Animals; Antigens, CD; Antigens, CD13; Antigens, Differentiation, Myelomonocytic; Aspergillus Nuclease S1; Bacteriophage lambda; Base Sequence; Cell Membrane; Cloning, Molecular; DNA; DNA Restriction Enzymes; Endonucleases; Exons; Humans; Introns; Molecular Sequence Data; Nucleic Acid Hybridization; Promoter Regions (Genetics); RNA, Messenger; Regulatory Sequences, Nucleic Acid; Sequence Homology, Nucleic Acid; Swine; Transcription, Genetic; alpha 1-Antitrypsin",
year = "1989",
language = "English",
volume = "251",
pages = "275--81",
journal = "F E B S Letters",
issn = "0014-5793",
publisher = "JohnWiley & Sons Ltd",
number = "1-2",

}

RIS

TY - JOUR

T1 - Cloning of the pig aminopeptidase N gene. Identification of possible regulatory elements and the exon distribution in relation to the membrane-spanning region.

AU - Sjöström, H

AU - Norén, O

AU - Olsen, Jørgen

N1 - Keywords: Alkaline Phosphatase; Amino Acid Sequence; Aminopeptidases; Animals; Antigens, CD; Antigens, CD13; Antigens, Differentiation, Myelomonocytic; Aspergillus Nuclease S1; Bacteriophage lambda; Base Sequence; Cell Membrane; Cloning, Molecular; DNA; DNA Restriction Enzymes; Endonucleases; Exons; Humans; Introns; Molecular Sequence Data; Nucleic Acid Hybridization; Promoter Regions (Genetics); RNA, Messenger; Regulatory Sequences, Nucleic Acid; Sequence Homology, Nucleic Acid; Swine; Transcription, Genetic; alpha 1-Antitrypsin

PY - 1989

Y1 - 1989

N2 - We have isolated four lambda-phages covering the complete pig aminopeptidase N/CD13 gene. The sequence of 2.85 kbp encompasses 1.18 kbp of the 5' upstream region and 1.67 kbp of the structural gene. In the promoter region we find a TATA box and potential binding sites for CTF-1/NF-1 and AP-2. By sequence comparisons we have found three domains showing similarity to promoter regions of the genes encoding human alpha 1-antitrypsin and human intestinal alkaline phosphatase. The gene sequence includes the first three exons and two introns. It shows that a single exon encodes the cytoplasmic tail, the membrane anchor and the junctional peptide.

AB - We have isolated four lambda-phages covering the complete pig aminopeptidase N/CD13 gene. The sequence of 2.85 kbp encompasses 1.18 kbp of the 5' upstream region and 1.67 kbp of the structural gene. In the promoter region we find a TATA box and potential binding sites for CTF-1/NF-1 and AP-2. By sequence comparisons we have found three domains showing similarity to promoter regions of the genes encoding human alpha 1-antitrypsin and human intestinal alkaline phosphatase. The gene sequence includes the first three exons and two introns. It shows that a single exon encodes the cytoplasmic tail, the membrane anchor and the junctional peptide.

M3 - Journal article

C2 - 2568950

VL - 251

SP - 275

EP - 281

JO - F E B S Letters

JF - F E B S Letters

SN - 0014-5793

IS - 1-2

ER -

ID: 6586522