Chemical and photochemical probing of DNA complexes
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
An overview of the chemical and photochemical probes which over the past ten years have been used in studies of DNA/ligand complexes and of non-B-form DNA conformations is presented with emphasis on the chemical reactions of the probes with DNA and on their present 'use-profile'. The chemical probes include: dimethyl sulfate, ethyl nitroso urea, diethyl pyrocarbonate, osmium tetroxide, permanganate, aldehydes, methidiumpropyl-EDTA-Fell (MPE), phenanthroline metal complexes and EDTA/FeII. The photochemical probes that have been used include: psoralens, UVB, acridines and uranyl salts. The biological systems analysed by use of these probes are reviewed by tabulation.
Originalsprog | Engelsk |
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Tidsskrift | Journal of Molecular Recognition |
Vol/bind | 3 |
Udgave nummer | 1 |
Sider (fra-til) | 1-25 |
Antal sider | 25 |
ISSN | 0952-3499 |
DOI | |
Status | Udgivet - feb. 1990 |
ID: 203632798