AUGMENTATION OF HUMAN LYMPHOCYTE PROLIFERATIVE RESPONSES IN VITROBY PYRIMETHAMINE

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Standard

AUGMENTATION OF HUMAN LYMPHOCYTE PROLIFERATIVE RESPONSES IN VITROBY PYRIMETHAMINE. / BYGBJERG, IB CHRISTIAN.

I: Acta Pathologica Microbiologica Scandinavica Section C Immunology, Bind 89 C, Nr. 1-6, 01.01.1981, s. 111-114.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

BYGBJERG, IBCHRISTIAN 1981, 'AUGMENTATION OF HUMAN LYMPHOCYTE PROLIFERATIVE RESPONSES IN VITROBY PYRIMETHAMINE', Acta Pathologica Microbiologica Scandinavica Section C Immunology, bind 89 C, nr. 1-6, s. 111-114. https://doi.org/10.1111/j.1699-0463.1981.tb02673.x

APA

BYGBJERG, IB. CHRISTIAN. (1981). AUGMENTATION OF HUMAN LYMPHOCYTE PROLIFERATIVE RESPONSES IN VITROBY PYRIMETHAMINE. Acta Pathologica Microbiologica Scandinavica Section C Immunology, 89 C(1-6), 111-114. https://doi.org/10.1111/j.1699-0463.1981.tb02673.x

Vancouver

BYGBJERG IBCHRISTIAN. AUGMENTATION OF HUMAN LYMPHOCYTE PROLIFERATIVE RESPONSES IN VITROBY PYRIMETHAMINE. Acta Pathologica Microbiologica Scandinavica Section C Immunology. 1981 jan. 1;89 C(1-6):111-114. https://doi.org/10.1111/j.1699-0463.1981.tb02673.x

Author

BYGBJERG, IB CHRISTIAN. / AUGMENTATION OF HUMAN LYMPHOCYTE PROLIFERATIVE RESPONSES IN VITROBY PYRIMETHAMINE. I: Acta Pathologica Microbiologica Scandinavica Section C Immunology. 1981 ; Bind 89 C, Nr. 1-6. s. 111-114.

Bibtex

@article{9e5bbd04a9744d99a77524192891917b,
title = "AUGMENTATION OF HUMAN LYMPHOCYTE PROLIFERATIVE RESPONSES IN VITROBY PYRIMETHAMINE",
abstract = "Thymidine incorporation by human blood mononuclear cells, unstimulated and stimulated with phytohaemagglutinin (PHA), pokeweed mitogen (PWM) and purified protein derivate of tuberculin (PPD) was studied with and without addition of pyrimethamine. Responses were increased significantly by pyrimethamine in the PWM and PPD stimulated cultures, in the PPD cultures even by concentrations of pyrimethamine, which can be achieved with therapeutic doses of this drug. The closely related compound trimethoprim did not alter PHA‐, PWM‐ and PPD‐responses significantly. The possibility of using pyrimethamine ‐ a widely used prophylactic antimalarial ‐ as an immunopotentiator is mentioned. 1981 Acta Pathologica, Microbiologica et Immunologica Scandinavica",
keywords = "Antimalarials, immunopotention, lymphocyte transformation, pyrimethamine, trimethoprim",
author = "BYGBJERG, {IB CHRISTIAN}",
year = "1981",
month = jan,
day = "1",
doi = "10.1111/j.1699-0463.1981.tb02673.x",
language = "English",
volume = "89 C",
pages = "111--114",
journal = "Acta Pathologica et Microbiologica Scandinavica - Section C Immunology",
issn = "0304-1328",
publisher = "Wiley-Blackwell",
number = "1-6",

}

RIS

TY - JOUR

T1 - AUGMENTATION OF HUMAN LYMPHOCYTE PROLIFERATIVE RESPONSES IN VITROBY PYRIMETHAMINE

AU - BYGBJERG, IB CHRISTIAN

PY - 1981/1/1

Y1 - 1981/1/1

N2 - Thymidine incorporation by human blood mononuclear cells, unstimulated and stimulated with phytohaemagglutinin (PHA), pokeweed mitogen (PWM) and purified protein derivate of tuberculin (PPD) was studied with and without addition of pyrimethamine. Responses were increased significantly by pyrimethamine in the PWM and PPD stimulated cultures, in the PPD cultures even by concentrations of pyrimethamine, which can be achieved with therapeutic doses of this drug. The closely related compound trimethoprim did not alter PHA‐, PWM‐ and PPD‐responses significantly. The possibility of using pyrimethamine ‐ a widely used prophylactic antimalarial ‐ as an immunopotentiator is mentioned. 1981 Acta Pathologica, Microbiologica et Immunologica Scandinavica

AB - Thymidine incorporation by human blood mononuclear cells, unstimulated and stimulated with phytohaemagglutinin (PHA), pokeweed mitogen (PWM) and purified protein derivate of tuberculin (PPD) was studied with and without addition of pyrimethamine. Responses were increased significantly by pyrimethamine in the PWM and PPD stimulated cultures, in the PPD cultures even by concentrations of pyrimethamine, which can be achieved with therapeutic doses of this drug. The closely related compound trimethoprim did not alter PHA‐, PWM‐ and PPD‐responses significantly. The possibility of using pyrimethamine ‐ a widely used prophylactic antimalarial ‐ as an immunopotentiator is mentioned. 1981 Acta Pathologica, Microbiologica et Immunologica Scandinavica

KW - Antimalarials

KW - immunopotention

KW - lymphocyte transformation

KW - pyrimethamine

KW - trimethoprim

UR - http://www.scopus.com/inward/record.url?scp=0019471628&partnerID=8YFLogxK

U2 - 10.1111/j.1699-0463.1981.tb02673.x

DO - 10.1111/j.1699-0463.1981.tb02673.x

M3 - Journal article

C2 - 7293778

AN - SCOPUS:0019471628

VL - 89 C

SP - 111

EP - 114

JO - Acta Pathologica et Microbiologica Scandinavica - Section C Immunology

JF - Acta Pathologica et Microbiologica Scandinavica - Section C Immunology

SN - 0304-1328

IS - 1-6

ER -

ID: 203862554