Ændringer i blodprofiler under Tour de France 2007
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Ændringer i blodprofiler under Tour de France 2007. / Mørkeberg, Jakob; Belhage, Bo; Damsgaard, Rasmus.
I: Ugeskrift for læger, Bind 170, Nr. 22, 26.05.2008, s. 1916-9.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Ændringer i blodprofiler under Tour de France 2007
AU - Mørkeberg, Jakob
AU - Belhage, Bo
AU - Damsgaard, Rasmus
N1 - Keywords: Bicycling; Doping in Sports; Hematocrit; Hemoglobins; Humans; Male; Time Factors
PY - 2008/5/26
Y1 - 2008/5/26
N2 - INTRODUCTION: Marked changes in different blood variables, e.g. hemoglobin concentration ([Hb]) and hematocrit (Hct), are indications of blood manipulation. Blood sampling and the development of individual, longitudinal blood profiles have therefore been implemented in doping control in different sports federations. MATERIALS AND METHODS: During the Tour de France 2007, 7 riders were randomly tested on 3 different occasions; the day before the prologue, and 12 and 19 days after the prologue. Blood was drawn into 3 mL EDTA covered tubes and kept at 4 degrees Celsius. They were analyzed within 24 hours on a Sysmex R-500. RESULTS: [Hb] and Hct were significantly lower on day 12 (p = 0.005) and day 19 (p < 0.001) compared to baseline. All 7 riders had lower [Hb] and Hct on day 19 compared to baseline, while this was the case in 6 out of 7 riders already on day 12. The [Hb] and Hct were 11.5% and 12.1% lower on day 19 compared to baseline. CONCLUSION: We observed significant decreases in [Hb] and Hct in 7 riders during Tour de France 2007. Whether or not this is due to decrease in hemoglobin mass or hemodilution, or the latter solely, increases in [Hb] and Hct during prolonged stage racing seem unphysiological and should therefore lead to further examination of the rider. Udgivelsesdato: 2008-May
AB - INTRODUCTION: Marked changes in different blood variables, e.g. hemoglobin concentration ([Hb]) and hematocrit (Hct), are indications of blood manipulation. Blood sampling and the development of individual, longitudinal blood profiles have therefore been implemented in doping control in different sports federations. MATERIALS AND METHODS: During the Tour de France 2007, 7 riders were randomly tested on 3 different occasions; the day before the prologue, and 12 and 19 days after the prologue. Blood was drawn into 3 mL EDTA covered tubes and kept at 4 degrees Celsius. They were analyzed within 24 hours on a Sysmex R-500. RESULTS: [Hb] and Hct were significantly lower on day 12 (p = 0.005) and day 19 (p < 0.001) compared to baseline. All 7 riders had lower [Hb] and Hct on day 19 compared to baseline, while this was the case in 6 out of 7 riders already on day 12. The [Hb] and Hct were 11.5% and 12.1% lower on day 19 compared to baseline. CONCLUSION: We observed significant decreases in [Hb] and Hct in 7 riders during Tour de France 2007. Whether or not this is due to decrease in hemoglobin mass or hemodilution, or the latter solely, increases in [Hb] and Hct during prolonged stage racing seem unphysiological and should therefore lead to further examination of the rider. Udgivelsesdato: 2008-May
M3 - Tidsskriftartikel
C2 - 18513473
VL - 170
SP - 1916
EP - 1919
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 22
ER -
ID: 19119428