A subset of human pancreatic beta cells express functional CD14 receptors: a signaling pathway for beta cell-related glycolipids, sulfatide and ß-galactosylceramide
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
T1DM is a T-cell-mediated autoimmune disease targeting insulin-producing beta-cells. Multiple factors may contribute to the development of T1DM. Among these, the metabolic state of beta-cells and pro-inflammatory cytokines, produced by infiltrating immune cells, have been implicated in the precipitation of T1DM.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Diabetes - Metabolism: Research and Reviews (Online Edition) |
Vol/bind | 26 |
Udgave nummer | 8 |
Sider (fra-til) | 656-67 |
Antal sider | 12 |
ISSN | 1520-7560 |
DOI | |
Status | Udgivet - 1 nov. 2010 |
ID: 34204644