A "new" primed lymphocyte typing (PLT) defined DP-antigen associated with a private HLA--DR antigen

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Standard

A "new" primed lymphocyte typing (PLT) defined DP-antigen associated with a private HLA--DR antigen. / Morling, N; Jakobsen, B K; Platz, P.; Ryder, L P; Svejgaard, A; Thomsen, M.

I: HLA, Bind 16, Nr. 1, 1980, s. 95-104.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Morling, N, Jakobsen, BK, Platz, P, Ryder, LP, Svejgaard, A & Thomsen, M 1980, 'A "new" primed lymphocyte typing (PLT) defined DP-antigen associated with a private HLA--DR antigen', HLA, bind 16, nr. 1, s. 95-104. https://doi.org/10.1111/j.1399-0039.1980.tb00292.x

APA

Morling, N., Jakobsen, B. K., Platz, P., Ryder, L. P., Svejgaard, A., & Thomsen, M. (1980). A "new" primed lymphocyte typing (PLT) defined DP-antigen associated with a private HLA--DR antigen. HLA, 16(1), 95-104. https://doi.org/10.1111/j.1399-0039.1980.tb00292.x

Vancouver

Morling N, Jakobsen BK, Platz P, Ryder LP, Svejgaard A, Thomsen M. A "new" primed lymphocyte typing (PLT) defined DP-antigen associated with a private HLA--DR antigen. HLA. 1980;16(1):95-104. https://doi.org/10.1111/j.1399-0039.1980.tb00292.x

Author

Morling, N ; Jakobsen, B K ; Platz, P. ; Ryder, L P ; Svejgaard, A ; Thomsen, M. / A "new" primed lymphocyte typing (PLT) defined DP-antigen associated with a private HLA--DR antigen. I: HLA. 1980 ; Bind 16, Nr. 1. s. 95-104.

Bibtex

@article{28c30f70b1c511df825b000ea68e967b,
title = "A {"}new{"} primed lymphocyte typing (PLT) defined DP-antigen associated with a private HLA--DR antigen",
abstract = "We have recently described a {"}new{"} private HLA-DR antigen, DR{"}LTM{"}, which has a frequency of approximately 0.6% in Danes. Primed Lymphocyte Typing (PLT) cells directed towards DR{"}LTM{"}-associated determinants were generated in vitro by haplotype primings in two unrelated families with DR{"}LTM{"} positive individuals. Both PLT-cells reacted in parallel and gave positive reactions with (i) two unrelated and (ii) eight related individuals, all of whom were DR{"}LTM{"}-positive. Both PLT-cells gave negative reactions with (i) 38 unrelated and (ii) 15 related DR{"}LTM{"}-negative individuals. Thus, there was total agreement between the results obtained by HLA-DR typing with the antiserum {"}LTM{"} and by PLT-typing with these two haplotype primed PLT-cells. None of the DP{"}LTM{"}-positive individuals carried more than one of the antigens HLA-Dw/-DRw/DP1-8 and the local specificity D/DP{"}H{"}. Accordingly, this {"}new{"} PLT-defined antigen, DP{"}LTM{"}, most probably belongs to the series of HLA-D/DR-associated DP-antigens previously described.",
author = "N Morling and Jakobsen, {B K} and P. Platz and Ryder, {L P} and A Svejgaard and M Thomsen",
note = "Keywords: Arthritis, Juvenile Rheumatoid; B-Lymphocytes; Diabetes Mellitus; Epitopes; Female; Haploidy; Histocompatibility Antigens Class II; Histocompatibility Testing; Humans; Male; Multiple Sclerosis; Protein Biosynthesis",
year = "1980",
doi = "10.1111/j.1399-0039.1980.tb00292.x",
language = "English",
volume = "16",
pages = "95--104",
journal = "HLA",
issn = "2059-2302",
publisher = "Wiley",
number = "1",

}

RIS

TY - JOUR

T1 - A "new" primed lymphocyte typing (PLT) defined DP-antigen associated with a private HLA--DR antigen

AU - Morling, N

AU - Jakobsen, B K

AU - Platz, P.

AU - Ryder, L P

AU - Svejgaard, A

AU - Thomsen, M

N1 - Keywords: Arthritis, Juvenile Rheumatoid; B-Lymphocytes; Diabetes Mellitus; Epitopes; Female; Haploidy; Histocompatibility Antigens Class II; Histocompatibility Testing; Humans; Male; Multiple Sclerosis; Protein Biosynthesis

PY - 1980

Y1 - 1980

N2 - We have recently described a "new" private HLA-DR antigen, DR"LTM", which has a frequency of approximately 0.6% in Danes. Primed Lymphocyte Typing (PLT) cells directed towards DR"LTM"-associated determinants were generated in vitro by haplotype primings in two unrelated families with DR"LTM" positive individuals. Both PLT-cells reacted in parallel and gave positive reactions with (i) two unrelated and (ii) eight related individuals, all of whom were DR"LTM"-positive. Both PLT-cells gave negative reactions with (i) 38 unrelated and (ii) 15 related DR"LTM"-negative individuals. Thus, there was total agreement between the results obtained by HLA-DR typing with the antiserum "LTM" and by PLT-typing with these two haplotype primed PLT-cells. None of the DP"LTM"-positive individuals carried more than one of the antigens HLA-Dw/-DRw/DP1-8 and the local specificity D/DP"H". Accordingly, this "new" PLT-defined antigen, DP"LTM", most probably belongs to the series of HLA-D/DR-associated DP-antigens previously described.

AB - We have recently described a "new" private HLA-DR antigen, DR"LTM", which has a frequency of approximately 0.6% in Danes. Primed Lymphocyte Typing (PLT) cells directed towards DR"LTM"-associated determinants were generated in vitro by haplotype primings in two unrelated families with DR"LTM" positive individuals. Both PLT-cells reacted in parallel and gave positive reactions with (i) two unrelated and (ii) eight related individuals, all of whom were DR"LTM"-positive. Both PLT-cells gave negative reactions with (i) 38 unrelated and (ii) 15 related DR"LTM"-negative individuals. Thus, there was total agreement between the results obtained by HLA-DR typing with the antiserum "LTM" and by PLT-typing with these two haplotype primed PLT-cells. None of the DP"LTM"-positive individuals carried more than one of the antigens HLA-Dw/-DRw/DP1-8 and the local specificity D/DP"H". Accordingly, this "new" PLT-defined antigen, DP"LTM", most probably belongs to the series of HLA-D/DR-associated DP-antigens previously described.

U2 - 10.1111/j.1399-0039.1980.tb00292.x

DO - 10.1111/j.1399-0039.1980.tb00292.x

M3 - Journal article

C2 - 6162231

VL - 16

SP - 95

EP - 104

JO - HLA

JF - HLA

SN - 2059-2302

IS - 1

ER -

ID: 21608969