Generation and propagation of radical reactions on proteins

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Generation and propagation of radical reactions on proteins. / Hawkins, C L; Davies, Michael Jonathan.

In: B B A - Reviews on Cancer, Vol. 1504, No. 2-3, 02.04.2001, p. 196-219.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Hawkins, CL & Davies, MJ 2001, 'Generation and propagation of radical reactions on proteins', B B A - Reviews on Cancer, vol. 1504, no. 2-3, pp. 196-219.

APA

Hawkins, C. L., & Davies, M. J. (2001). Generation and propagation of radical reactions on proteins. B B A - Reviews on Cancer, 1504(2-3), 196-219.

Vancouver

Hawkins CL, Davies MJ. Generation and propagation of radical reactions on proteins. B B A - Reviews on Cancer. 2001 Apr 2;1504(2-3):196-219.

Author

Hawkins, C L ; Davies, Michael Jonathan. / Generation and propagation of radical reactions on proteins. In: B B A - Reviews on Cancer. 2001 ; Vol. 1504, No. 2-3. pp. 196-219.

Bibtex

@article{dfb21624941044fab31291738f184611,
title = "Generation and propagation of radical reactions on proteins",
abstract = "The oxidation of proteins by free radicals is thought to play a major role in many oxidative processes within cells and is implicated in a number of human diseases as well as ageing. This review summarises information on the formation of radicals on peptides and proteins and how radical damage may be propagated and transferred within protein structures. The emphasis of this article is primarily on the deleterious actions of radicals generated on proteins, and their mechanisms of action, rather than on enzymatic systems where radicals are deliberately formed as transient intermediates. The final section of this review examines the control of protein oxidation and how such damage might be limited by antioxidants.",
keywords = "Alcohols, Animals, Antioxidants, Binding Sites, Electron Spin Resonance Spectroscopy, Free Radicals, Humans, Kinetics, Models, Chemical, Oxidation-Reduction, Peroxides, Phenols, Proteins",
author = "Hawkins, {C L} and Davies, {Michael Jonathan}",
year = "2001",
month = apr,
day = "2",
language = "English",
volume = "1504",
pages = "196--219",
journal = "Biochimica et Biophysica Acta - Reviews on Cancer",
issn = "0304-419X",
publisher = "Elsevier",
number = "2-3",

}

RIS

TY - JOUR

T1 - Generation and propagation of radical reactions on proteins

AU - Hawkins, C L

AU - Davies, Michael Jonathan

PY - 2001/4/2

Y1 - 2001/4/2

N2 - The oxidation of proteins by free radicals is thought to play a major role in many oxidative processes within cells and is implicated in a number of human diseases as well as ageing. This review summarises information on the formation of radicals on peptides and proteins and how radical damage may be propagated and transferred within protein structures. The emphasis of this article is primarily on the deleterious actions of radicals generated on proteins, and their mechanisms of action, rather than on enzymatic systems where radicals are deliberately formed as transient intermediates. The final section of this review examines the control of protein oxidation and how such damage might be limited by antioxidants.

AB - The oxidation of proteins by free radicals is thought to play a major role in many oxidative processes within cells and is implicated in a number of human diseases as well as ageing. This review summarises information on the formation of radicals on peptides and proteins and how radical damage may be propagated and transferred within protein structures. The emphasis of this article is primarily on the deleterious actions of radicals generated on proteins, and their mechanisms of action, rather than on enzymatic systems where radicals are deliberately formed as transient intermediates. The final section of this review examines the control of protein oxidation and how such damage might be limited by antioxidants.

KW - Alcohols

KW - Animals

KW - Antioxidants

KW - Binding Sites

KW - Electron Spin Resonance Spectroscopy

KW - Free Radicals

KW - Humans

KW - Kinetics

KW - Models, Chemical

KW - Oxidation-Reduction

KW - Peroxides

KW - Phenols

KW - Proteins

M3 - Journal article

C2 - 11245785

VL - 1504

SP - 196

EP - 219

JO - Biochimica et Biophysica Acta - Reviews on Cancer

JF - Biochimica et Biophysica Acta - Reviews on Cancer

SN - 0304-419X

IS - 2-3

ER -

ID: 138280278