Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty. / Plamboeck, Astrid; Veedfald, Simon; Deacon, Carolyn; Hartmann, Bolette; Wettergren, Andre; Svendsen, Lars Bo; Meisner, Søren; Hovendal, Claus; Knop, Filip Krag; Vilsbøll, Tina; Holst, Jens Juul.

In: European Journal of Endocrinology, Vol. 169, 23.05.2013, p. 187-201.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Plamboeck, A, Veedfald, S, Deacon, C, Hartmann, B, Wettergren, A, Svendsen, LB, Meisner, S, Hovendal, C, Knop, FK, Vilsbøll, T & Holst, JJ 2013, 'Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty', European Journal of Endocrinology, vol. 169, pp. 187-201. https://doi.org/10.1530/EJE-13-0264

APA

Plamboeck, A., Veedfald, S., Deacon, C., Hartmann, B., Wettergren, A., Svendsen, L. B., ... Holst, J. J. (2013). Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty. European Journal of Endocrinology, 169, 187-201. https://doi.org/10.1530/EJE-13-0264

Vancouver

Plamboeck A, Veedfald S, Deacon C, Hartmann B, Wettergren A, Svendsen LB et al. Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty. European Journal of Endocrinology. 2013 May 23;169:187-201. https://doi.org/10.1530/EJE-13-0264

Author

Plamboeck, Astrid ; Veedfald, Simon ; Deacon, Carolyn ; Hartmann, Bolette ; Wettergren, Andre ; Svendsen, Lars Bo ; Meisner, Søren ; Hovendal, Claus ; Knop, Filip Krag ; Vilsbøll, Tina ; Holst, Jens Juul. / Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty. In: European Journal of Endocrinology. 2013 ; Vol. 169. pp. 187-201.

Bibtex

@article{a781d7ac2e2143bfa4737ed2a29c4c85,
title = "Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty",
abstract = "OBJECTIVE: Glucagon-like peptide-1 (GLP-1) is rapidly inactivated by dipeptidyl peptidase 4, but may interact with vagal neurons at its site of secretion. We investigated the role of vagal innervation for handling of oral and iv glucose. Design and methods: Truncally vagotomised subjects (n=16) and matched controls (n=10) underwent 50g oral glucose tolerance test (OGTT)±vildagliptin, a DPP-4 inhibitor (DPP-4i) and isoglycaemic iv glucose infusion (IIGI) copying the OGTT without DPP-4i. Results: Isoglycaemia was obtained with 25±2 g glucose in vagotomised subjects and 18±2 g in controls (P",
author = "Astrid Plamboeck and Simon Veedfald and Carolyn Deacon and Bolette Hartmann and Andre Wettergren and Svendsen, {Lars Bo} and S{\o}ren Meisner and Claus Hovendal and Knop, {Filip Krag} and Tina Vilsb{\o}ll and Holst, {Jens Juul}",
year = "2013",
month = "5",
day = "23",
doi = "10.1530/EJE-13-0264",
language = "English",
volume = "169",
pages = "187--201",
journal = "European Journal of Endocrinology",
issn = "0804-4643",
publisher = "BioScientifica Ltd.",

}

RIS

TY - JOUR

T1 - Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty

AU - Plamboeck, Astrid

AU - Veedfald, Simon

AU - Deacon, Carolyn

AU - Hartmann, Bolette

AU - Wettergren, Andre

AU - Svendsen, Lars Bo

AU - Meisner, Søren

AU - Hovendal, Claus

AU - Knop, Filip Krag

AU - Vilsbøll, Tina

AU - Holst, Jens Juul

PY - 2013/5/23

Y1 - 2013/5/23

N2 - OBJECTIVE: Glucagon-like peptide-1 (GLP-1) is rapidly inactivated by dipeptidyl peptidase 4, but may interact with vagal neurons at its site of secretion. We investigated the role of vagal innervation for handling of oral and iv glucose. Design and methods: Truncally vagotomised subjects (n=16) and matched controls (n=10) underwent 50g oral glucose tolerance test (OGTT)±vildagliptin, a DPP-4 inhibitor (DPP-4i) and isoglycaemic iv glucose infusion (IIGI) copying the OGTT without DPP-4i. Results: Isoglycaemia was obtained with 25±2 g glucose in vagotomised subjects and 18±2 g in controls (P

AB - OBJECTIVE: Glucagon-like peptide-1 (GLP-1) is rapidly inactivated by dipeptidyl peptidase 4, but may interact with vagal neurons at its site of secretion. We investigated the role of vagal innervation for handling of oral and iv glucose. Design and methods: Truncally vagotomised subjects (n=16) and matched controls (n=10) underwent 50g oral glucose tolerance test (OGTT)±vildagliptin, a DPP-4 inhibitor (DPP-4i) and isoglycaemic iv glucose infusion (IIGI) copying the OGTT without DPP-4i. Results: Isoglycaemia was obtained with 25±2 g glucose in vagotomised subjects and 18±2 g in controls (P

U2 - 10.1530/EJE-13-0264

DO - 10.1530/EJE-13-0264

M3 - Journal article

C2 - 23704713

VL - 169

SP - 187

EP - 201

JO - European Journal of Endocrinology

JF - European Journal of Endocrinology

SN - 0804-4643

ER -

ID: 45842367