Thomas Jespersen

Thomas Jespersen

Professor

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    ORCID: 0000-0001-6575-360X

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    1. Published

      Impact of arrhythmogenic calmodulin variants on small conductance Ca2+-activated K+ (SK3) channels

      Saljic, Arnela, Muthukumarasamy, K. M., la Cour, J. M., Boddum, K., Grunnet, Morten, Berchtold, Martin Werner & Jespersen, Thomas, 2019, In: Physiological Reports. 7, 19, 13 p., e14210.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      In vivo knockdown of SK3 channels using antisense oligonucleotides protects against atrial fibrillation in rats

      Saljic, Arnela, Soattin, Luca, Trachsel, D. S., Boddum, K. & Jespersen, Thomas, Oct 2020, In: Journal of Molecular and Cellular Cardiology. 147, p. 18-26

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Anti-arrhythmic investigations in large animal models of atrial fibrillation

      Saljic, Arnela, Jespersen, Thomas & Buhl, Rikke, 2022, In: British Journal of Pharmacology. 179, 5, p. 838-858

      Research output: Contribution to journal › Review › Research › peer-review

    4. Published

      Amiodarone Treatment in the Early Phase of Acute Myocardial Infarction Protects Against Ventricular Fibrillation in a Porcine Model

      Sattler, Stefan M, Lubberding, Anniek Frederike, Skibsbye, L., Jabbari, R., Wakili, R., Jespersen, Thomas & Tfelt-Hansen, Jacob, 2019, In: Journal of Cardiovascular Translational Research. 12, 4, p. 321-330

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Effect of the antipsychotic drug haloperidol on arrhythmias during acute myocardial infarction in a porcine model

      Sattler, Stefan M, Lubberding, Anniek Frederike, Kristensen, C. B., Møgelvang, R., Blanche, Paul Frédéric, Fink-Jensen, Anders, Engstrøm, Thomas, Kääb, S., Jespersen, Thomas & Tfelt-Hansen, Jacob, 2020, In: IJC Heart and Vasculature. 26, 100455.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Ventricular Arrhythmias in First Acute Myocardial Infarction: Epidemiology, Mechanisms, and Interventions in Large Animal Models

      Sattler, S. M., Skibsbye, L., Dr Linz, Dominik Karl, Lubberding, Anniek Frederike, Tfelt-Hansen, Jacob & Jespersen, Thomas, 2019, In: Frontiers in Cardiovascular Medicine. 6, 14 p., 158.

      Research output: Contribution to journal › Review › Research › peer-review

    7. Published

      KCNQ4 channel activation by BMS-204352 and retigabine

      Schrøder, R. L. K., Jespersen, Thomas, Christophersen, P., Strøbaek, D., Jensen, B. S. & Olesen, Poul, 1 Jun 2001, In: Neuropharmacology. 40, 7, p. 888-98 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Pharmacological inhibition of I-K1 by PA-6 in isolated rat hearts affects ventricular repolarization and refractoriness

      Skarsfeldt, M. A., Carstensen, Helena, Skibsbye, L., Tang, C., Buhl, Rikke, Bentzen, Bo Hjorth & Jespersen, Thomas, Apr 2016, In: Physiological Reports. 4, 8, 11 p., e12734.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium

      Skibsbye, L., Wang, X., Axelsen, L. N., Bomholtz, Sofia Hammami, Nielsen, Morten Schak, Grunnet, Morten, Bentzen, Bo Hjorth & Jespersen, Thomas, Aug 2015, In: Journal of Cardiovascular Pharmacology. 66, 2, p. 165-176 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria

      Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, 1 Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-67 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Inhibition of Small Conductance Calcium-Activated Potassium (SK) Channels Prevents Arrhythmias in Rat Atria During beta-Adrenergic and Muscarinic Receptor Activation

      Skibsbye, L., Bengaard, A. K., Uldum-Nielsen, A. M., Boddum, K., Christ, T. & Jespersen, Thomas, 2018, In: Frontiers in Physiology. 9

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarisation in human atria.

      Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-167 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Refractoriness in human atria: Time and voltage dependence of sodium channel availability

      Skibsbye, L., Jespersen, Thomas, Christ, T., Maleckar, M. M., van den Brink, J., Tavi, P. & Koivumäki, J. T., Dec 2016, In: Journal of Molecular and Cellular Cardiology. 101, p. 26-34 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Inhibition of Adenosine Pathway Alters Atrial Electrophysiology and Prevents Atrial Fibrillation

      Soattin, Luca, Lubberding, Anniek Frederike, Bentzen, Bo Hjorth, Christ, T. & Jespersen, Thomas, 2020, In: Frontiers in Physiology. 11, 14 p., 493.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      The Acetylcholine-Activated Potassium Current Inhibitor XAF-1407 Terminates Persistent Atrial Fibrillation in Goats

      Sobota, V., Gatta, G., van Hunnik, A., van Tuijn, I., Kuiper, M., Milnes, J., Jespersen, Thomas, Schotten, U. & Verheule, S., 2021, In: Frontiers in Pharmacology. 11, 13 p., 608410.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts

      Soltysinska, E., Olesen, Søren-Peter, Christ, T., Wettwer, E., Varró, A., Grunnet, Morten & Jespersen, Thomas, 2009, In: Pflügers Archiv: European Journal of Physiology. 459, 1, p. 11-23 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Cause-specific mortality in children and young adults with diabetes mellitus: A Danish nationwide cohort study

      Svane, Jesper, Lynge, T. H., Pedersen-Bjergaard, Ulrik, Jespersen, Thomas, Gislason, Gunnar Hilmar, Risgaard, B., Winkel, B. G. & Tfelt-Hansen, Jacob, 2021, In: European Journal of Preventive Cardiology. 28, 2, p. 159-165

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Biophysical characterization of inwardly rectifying potassium currents (I(K1) I(K,ACh), I(K,Ca)) using sinus rhythm or atrial fibrillation action potential waveforms

      Tang, C., Skibsbye, L., Yuan, L., Bentzen, Bo Hjorth & Jespersen, Thomas, Oct 2015, In: General Physiology and Biophysics. 34, 4, p. 383-92 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Biophysical characterization of KV3.1 potassium channel activating compounds

      Taskin, B., von Schoubye, N. L., Sheykhzade, Majid, Bastlund, J. F., Grunnet, M. & Jespersen, Thomas, 5 Jul 2015, In: European Journal of Pharmacology. 758, p. 164-170 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Inherited cardiac diseases caused by mutations in the Nav1.5 sodium channel.

      Tfelt-Hansen, Jacob, Winkel, B., Grunnet, Morten & Jespersen, Thomas, Oct 2009, In: Journal of Cardiovascular Electrophysiology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Ventricular tachycardia in a Brugada syndrome patient caused by a novel deletion in SCN5A

      Tfelt-Hansen, J., Jespersen, Thomas, Hofman-Bang, J., Rasmussen, Hanne Borger, Cedergreen, P., Skovby, F., Abriel, H., Svendsen, Jesper Hastrup, Olesen, S., Christiansen, M. & Haunso, S., 2009, In: Canadian Journal of Cardiology. 25, 3, p. 156-60 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Cardiac channelopathies and sudden infant death syndrome

      Tfelt-Hansen, J., Winkel, B. G., Grunnet, Morten & Jespersen, Thomas, 2011, In: The Cardiology. 119, 1, p. 21-33 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Arvelige hjertesygdomme forårsaget af natriumkanalmutationer

      Tfelt-Hansen, J., Olesen, Søren-Peter, Svendsen, Jesper Hastrup & Jespersen, Thomas, 2009, In: Ugeskrift for læger. 171, 15, p. 1261-5 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Inherited Cardiac Diseases Caused by Mutations in the Nav1.5 Sodium Channel

      Tfelt-Hansen, J., Winkel, B. G., Grunnet, Morten & Jespersen, Thomas, 2009, In: Cardiovascular Electrophysiology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Two missense mutations in KCNQ1 cause pituitary hormone deficiency and maternally inherited gingival fibromatosis

      Tommiska, J., Känsäkoski, J., Skibsbye, L., Vaaralahti, K., Liu, X., Lodge, E. J., Tang, C., Yuan, L., Fagerholm, R., Kanters, J. K., Lahermo, P., Kaunisto, M., Keski-Filppula, R., Vuoristo, S., Pulli, K., Ebeling, T., Valanne, L., Sankila, E-M., Kivirikko, S., Lääperi, M. & 15 others, Casoni, F., Giacobini, P., Phan-Hug, F., Buki, T., Tena-Sempere, M., Pitteloud, N., Veijola, R., Lipsanen-Nyman, M., Kaunisto, K., Mollard, P., Andoniadou, C. L., Hirsch, J. A., Varjosalo, M., Jespersen, Thomas & Raivio, T., 3 Nov 2017, In: Nature Communications. 8, 1, 11 p., 1289.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Population-based pediatric reference values for serum parathyroid hormone, vitamin D, calcium, and phosphate in Danish/North-European white children and adolescents

      Vissing Landgrebe, A., Lund, Morten Asp Vonsild, Lausten-Thomsen, U., Frithioff-Bøjsøe, C., Fonvig, Cilius Esmann, Lind Plesner, J., Aas Holm, L., Jespersen, Thomas, Hansen, Torben & Holm, Jens-Christian, 2021, In: Clinica Chimica Acta. 523, p. 483-490

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology

      Wang, X., Liang, B., Skibsbye, L., Olesen, Søren-Peter, Grunnet, Morten & Jespersen, Thomas, Aug 2013, In: Journal of Cardiovascular Pharmacology. 62, 2, p. 192-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      MR-proANP measured at admission is associated with incident atrial fibrillation in STEMI patients

      Wegener, A., Modin, D., Pedersen, S., Lindberg, S., Pareek, M., Iversen, Kasper, Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2022, In: Heart and Vessels. 37, p. 1906–1913 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome

      Winkel, B. G., Yuan, L., Olesen, Morten Steen Salling, Sadjadieh, G., Wang, Y., Risgaard, B., Jabbari, R., Haunsø, Stig, Holst, A. G., Hollegaard, M. V., Tfelt-Hansen, J. & Jespersen, Thomas, Jun 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 6, p. 1241-1249 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Identification of a Kir3.4 Mutation in Congenital Long QT Syndrome

      Yang, Y., Yang, Y., Liang, B., Liu, J., Li, J., Grunnet, M., Olesen, S-P., Rasmussen, H. B., Ellinor, P. T., Gao, L., Lin, X., Li, L., Wang, L., Xiao, J., Liu, Y., Liu, Y., Zhang, S., Liang, D., Peng, L., Jespersen, T. & 1 others, Chen, Y., 2010, In: American Journal of Human Genetics. 86, 6, p. 872-80 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant.

      Yuan, L., Koivumäki, J., Liang, B., Lorentzen, Lasse Gøbel, Tang, C., Andersen, M., Svendsen, J., Tfelt-Hansen, Jacob, Maleckar, M., Schmitt, Nicole, Olesen, M. & Jespersen, Thomas, Feb 2014, In: American journal of physiology. Heart and circulatory physiology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada Syndrome mutant

      Yuan, L., Koivumaki, J., Liang, B., Lorentzen, L. G., Tang, C., Andersen, M. N., Svendsen, Jesper Hastrup, Tfelt-Hansen, J., Maleckar, M., Schmitt, Nicole, Olesen, Morten Steen Salling & Jespersen, Thomas, 21 Feb 2014, In: American Journal of Physiology: Heart and Circulatory Physiology. 306, 8, p. H1204-12

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Pharmacological exploration of the resting membrane potential reserve: Impact on atrial fibrillation

      van der Heyden, M. A. G. & Jespersen, Thomas, 15 Jan 2016, In: European Journal of Pharmacology. 771, p. 56-64 9 p.

      Research output: Contribution to journal › Review › Research › peer-review

    34. Published

      Dynein regulates Kv7.4 channel trafficking from the cell membrane

      van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael J., Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      The sodium channel activator Lu AE98134 normalizes the altered firing properties of fast spiking interneurons in Dlx5/6+/- mice

      von Schoubye, N. L., Frederiksen, K., Kristiansen, Uffe, Petersen, A. V., Dalby, N. O., Grunnet, M., Jensen, H. S., Jespersen, Thomas, Sohal, V. S. & Perrier, Jean-Francois Marie, 2018, In: Neuroscience Letters. 662, p. 29-35 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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