Søren-Peter Olesen

Søren-Peter Olesen

Professor


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  1. Published

    A novel KCND3 gain-of-function mutation associated with early-onset of persistent lone atrial fibrillation

    Olesen, Morten Steen Salling, Refsgaard, L., Holst, A. G., Larsen, A. P., Grubb, Søren, Haunsø, Stig, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Schmitt, Nicole & Callø, Kirstine, 2013, In: Cardiovascular Research. 98, 3, p. 488-495 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein

    Andersen, M. N., Krzystanek, K., Petersen, F., Bomholtz, Sofia Hammami, Olesen, Søren-Peter, Abriel, H., Jespersen, Thomas & Rasmussen, Hanne Borger, 8 Nov 2013, In: The Journal of Biological Chemistry. 288, 52, p. 36841-54 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A radiolabeled peptide ligand of the hERG channel, [125I]-BeKm-1.

    Angelo, K., Korolkova, Y. V., Grunnet, Morten, Grishin, E. V., Pluzhnikov, K. A., Klærke, Dan Arne, Knaus, H., Møller, Morten & Olesen, Søren-Peter, 2003, In: Pflügers Archiv: European Journal of Physiology. 447, 1, p. 55-63 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome

    Callø, Kirstine, Cordeiro, J. M., Di Diego, J. M., Hansen, R. S., Grunnet, Morten, Olesen, Søren-Peter & Antzelevitch, C., 2008, In: Cardiovascular Research. 81, 4, p. 686-94 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    AMP-activated protein kinase downregulates Kv7.1 cell surface expression

    Andersen, M. N., Krzystanek, K., Jespersen, Thomas, Olesen, Søren-Peter & Rasmussen, Hanne Borger, 2012, In: Traffic. 13, 1, p. 143-56 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Acrylamides as potassium channel openers

    Nardit, A. & Olesen, Søren-Peter, 2007, In: Expert Opinion on Therapeutic Patents. 17, 10, p. 1215-1226 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Activation of ERG2 potassium channels by the diphenylurea NS1643.

    Elmedyb, P., Olesen, Søren-Peter & Grunnet, Morten, 2007, In: Neuropharmacology. 53, 2, p. 283-94 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Activation of HERG potassium channels by the diphenylurea NS1643

    Hansen, R. S., Diness, T. G., Christ, T., Demnitz, J., Ravens, U. & Olesen, Søren-Peter, 2006, In: Molecular Pharmacology. 69, p. 266-277

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Activation of KCNQ5 channels stably expressed in HEK293 cells by BMS-204352.

    Dupuis, D. S., Schrøder, R. L., Jespersen, Thomas, Christensen, J. K., Christophersen, P., Jensen, B. S. & Olesen, Søren-Peter, 2002, In: European Journal of Pharmacology. 437, 3, p. 129-37 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Activation of big conductance Ca(2+)-activated K (+) channels (BK) protects the heart against ischemia-reperfusion injury

    Bentzen, Bo Hjorth, Osadchii, O., Jespersen, Thomas, Hansen, R. S., Olesen, Søren-Peter & Grunnet, Morten, 2009, In: Pflügers Archiv: European Journal of Physiology. 457, 5, p. 979-88 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Activation of human IK and SK Ca2+ -activated K+ channels by NS309 (6,7-dichloro-1H-indole-2,3-dione 3-oxime).

    Strøbaek, D., Teuber, L., Jørgensen, T. D., Ahring, P. K., Kjaer, K., Hansen, R. S., Olesen, Søren-Peter, Christophersen, P. & Skaaning-Jensen, B., 2004, In: BBA General Subjects. 1665, 1-2, p. 1-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643).

    Hansen, R. S., Diness, T. G., Christ, T., Demnitz, J., Ravens, U., Olesen, Søren-Peter & Grunnet, Morten, 2005, In: Molecular Pharmacology. 69, 1, p. 266-77 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Activation of the human intermediate-conductance Ca2+-activated K+ channel by 1-ethyl-2-benzimidazolinone is strongly Ca2+-dependent

    Pedersen, K. A., Schrøder, R. L. K., Skanning-Jensen, B., Strøbæk, D., Olesen, Søren-Peter & Christophersen, P., 1999, In: BBA General Subjects. 77660, p. 01-10

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Activation of the human, intermediate-conductance, Ca2+-activated K+ channel by methylxanthines

    Schrøder, R. L. K., Jensen, B. S., Strøbaek, D., Olesen, Søren-Peter & Christophersen, P., 2000, In: Pflügers Archiv: European Journal of Physiology. 440, p. 809-818

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    An ERG channel inhibitor from the scorpion Buthus eupeus

    Korolkova, Y. V., Kozlov, S. A., Lipkin, A. V., Pluzhnikov, K. A., Hadley, J. K., Filippov, A. K., Brown, D. A., Pedersen, K. A., Strøbaek, D., Jespersen, Thomas, Olesen, Søren-Peter, Jensen Skanning, B. & Grishin, E. V., 30 Mar 2001, In: Journal of Biological Chemistry. 276, 13, p. 9868-76 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Analysis of the Antitumor Activity of Clotrimazole on A375 Human Melanoma Cells

    Adinolfi, B., Carpi, S., Romanini, A., Da Pozzo, E., Castagna, M., Costa, B., Martini, C., Olesen, Søren-Peter, Schmitt, Nicole, Breschi, M. C., Nieri, P. & Fogli, S., Jul 2015, In: Anticancer Research. 35, 7, p. 3781-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

    Lundby, A., Rossin, E. J., Steffensen, A. B., Acha, M. R., Newton-Cheh, C., Pfeufer, A., Lynch, S. N., Olesen, S-P., Brunak, S., Ellinor, P. T., Jukema, J. W., Trompet, S., Ford, I., Macfarlane, P. W., Krijthe, B. P., Hofman, A., Uitterlinden, A. G., Stricker, B. H., Nathoe, H. M., Spiering, W. & 8 others, Daly, M. J., Asselbergs, F. W., van der Harst, P., Milan, D. J., de Bakker, P. I. W., Hansen, K. L., Olsen, Jesper Velgaard & The QT Interval International GWAS Consortium (QT-IGC), T. Q. I. I. G. C. (., 22 Jun 2014, In: Nature Methods. 11, 8, p. 868-874 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Antiarrhythmic properties of a rapid delayed-rectifier current activator in rabbit models of acquired long QT syndrome.

    Diness, T. G., Yeh, Y., Qi, X. Y., Chartier, D., Tsuji, Y., Hansen, R. S., Olesen, Søren-Peter, Grunnet, Morten & Nattel, S., 2008, In: Cardiovascular Research. 79, 1, p. 61-69 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Apamin interacts with all subtypes of cloned small-conductance Ca2+-activated K+ channels

    Grunnet, Morten, Jensen, B. S., Olesen, Søren-Peter & Klærke, Dan Arne, 2001, In: Pflügers Archiv: European Journal of Physiology. 441, p. 544-550

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Arvelige hjertesygdomme forårsaget af natriumkanalmutationer

    Tfelt-Hansen, J., Olesen, Søren-Peter, Svendsen, Jesper Hastrup & Jespersen, Thomas, 2009, In: Ugeskrift for læger. 171, 15, p. 1261-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    BK channel activation by NS11021 decreases excitability and contractility of urinary bladder smooth muscle

    Layne, J. J., Nausch, B., Olesen, Søren-Peter & Nelson, M. T., 2009, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 298, 2, p. R378-84

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    BK channel activators and their therapeutic perspectives

    Bentzen, Bo Hjorth, Olesen, Søren-Peter, Rønn, L. C. B. & Grunnet, Morten, 2014, In: Frontiers in Physiology. 5, p. 1-12 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    BK channel modulators: a comprehensive overview.

    Nardi, A. & Olesen, Søren-Peter, 2008, In: Current Medicinal Chemistry. 15, 11, p. 1126-46 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif.

    Jespersen, Thomas, Rasmussen, Hanne Borger, Grunnet, Morten, Jensen, H. S., Angelo, K., Dupuis, D. S., Vogel, L. K., Jorgensen, N. K., Klærke, Dan Arne & Olesen, Søren-Peter, 2004, In: Journal of Cell Science. 117, Pt 19, p. 4517-26 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Biophysical characterization of the new human ether-a-go-go-related gene channel opener NS3623[N-(4-bromo-2-(1H-tetrazol-5-yl)-phenyl)-N '-(3 '-trifluoromethylphenyl)urea]

    Hansen, R. S., Diness, T. G., Christ, T., Wettwer, E., Ravens, U., Olesen, Søren-Peter & Grunnet, Morten, 2006, In: Molecular Pharmacology. 70, 4, p. 1319-1329 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Biophysical characterization of the short QT mutation hERG-N588K reveals a mixed gain-and loss-of-function

    Grunnet, Morten, Diness, T. G., Hansen, R. S. & Olesen, Søren-Peter, 2008, In: Cellular Physiology and Biochemistry. 22, 5-6, p. 611-624 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Blockade of Ca2+-activated K+ channels in T cells: an option for the treatment of multiple sclerosis?

    Madsen, L. S., Christophersen, P. & Olesen, Søren-Peter, 2005, In: European Journal of Immunology. 35, 4, p. 1023-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Bureaukrati, Bogholderi og Bullshit

    Harder, Peter, Bache, C., Flensted-Jensen, M., Koch, Lene, Olesen, Søren-Peter & Sand-Jensen, Kaj, 30 Oct 2009, In: Weekendavisen.

    Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication

  29. Published

    CNTF inhibits high voltage activated Ca2+ currents in fetal mouse cortical neurones.

    Holm, N. R., Christophersen, P., Hounsgaard, Jørn Dybkjær, Gammeltoft, S. & Olesen, Søren-Peter, 2002, In: Journal of Neurochemistry. 82, 3, p. 495-503 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Cardiac potassium channel subtypes: new roles in repolarization and arrhythmia

    Schmitt, Nicole, Grunnet, Morten & Olesen, Søren-Peter, Apr 2014, In: Physiological Reviews. 94, 2, p. 609-53 45 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Cell swelling activates cloned Ca(2+)-activated K(+) channels: a role for the F-actin cytoskeleton.

    Jorgensen, N. K., Pedersen, Stine Helene Falsig, Rasmussen, Hanne Borger, Grunnet, Morten, Klærke, Dan Arne & Olesen, Søren-Peter, 2003, In: BBA General Subjects. 1615, 1-2, p. 115-25 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Chamber-specific effects of hypokalaemia on ventricular arrhythmogenicity in isolated, perfused guinea-pig heart

    Osadchii, O. E., Bentzen, Bo Hjorth & Olesen, Søren-Peter, 2009, In: Experimental Physiology. 94, 4, p. 434-46 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Characterization of cardiac repolarization in the Göttingen minipig

    Laursen, M., Olesen, Søren-Peter, Grunnet, Morten, Mow, T., Jespersen, T. & Jespersen, Thomas, 2011, In: Journal of Pharmacological and Toxicological Methods. 63, 2, p. 186-95 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current.

    Larsen, A. P., Olesen, Søren-Peter, Grunnet, Morten & Jespersen, Thomas, 2008, In: Pflügers Archiv: European Journal of Physiology. 456, 6, p. 1137-48 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Characterization of the cloned human intermediate-conductance Ca*O2*O+-activated K*O+ channel

    Jensen, B. S., Strøbæk, D., Christophersen, P., Jørgensen, T. D., Hansen, C., Silahtaroglu, Asli, Olesen, Søren-Peter & Ahring, P. K., 1998, In: The American Physiological Society. p. 848-856

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Characterization of two new dominant ClC-1 channel mutations associated with myotonia.

    Grunnet, Morten, Jespersen, Thomas, Colding-Jørgensen, E., Schwartz, M., Klærke, Dan Arne, Vissing, John, Olesen, Søren-Peter & Dunø, M., 2003, In: Muscle & Nerve. 28, 6, p. 722-32 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Characterizations of a loss-of-function mutation in the Kir3.4 channel subunit.

    Callø, Kirstine, Ravn, L. S., Schmitt, Nicole, Sui, J. L., Duno, M., Haunso, S., Grunnet, Morten, Svendsen, J. H. & Olesen, Søren-Peter, 2007, In: Biochemical and Biophysical Research Communications. 364, 4, p. 889-95 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Chronic sympathetic activation promotes downregulation of ß-adrenoceptor-mediated effects in the guinea pig heart independently of structural remodeling and systolic dysfunction

    Soltysinska, E., Thiele, S., Osadchiy, O. & Olesen, Søren-Peter, 2011, In: Pflügers Archiv - European Journal of Physiology. 462, 4, p. 529-43 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Comparison of the Effects of a Transient Outward Potassium Channel Activator on Currents Recorded from Atrial and Ventricular Cardiomyocytes.

    Callø, Kirstine, Nof, E., Jespersen, Thomas, Di Diego, J. M., Chlus, N., Olesen, Søren-Peter, Antzelevitch, C. & Cordeiro, J. M., 2011, In: Journal of Cardiovascular Electrophysiology. 22, 9, p. 1057-1066 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Computational analysis of the effects of the hERG channel opener NS1643 in a human ventricular cell model.

    Peitersen, T., Grunnet, Morten, Benson, A. P., Holden, A. V., von Holstein-Rathlou, Niels-Henrik & Olesen, Søren-Peter, 2008, In: Heart Rhythm. 5, 5, p. 734-41 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Contribution of KV7 Channels to Basal Coronary Flow and Active Response to Ischemia

    Khanamiri, S., Soltysinska, E., Jepps, Thomas Andrew Qvistgaard, Bentzen, Bo Hjorth, Chadha, P. S., Schmitt, Nicole, Greenwood, I. A. & Olesen, Søren-Peter, 30 Sep 2013, In: Hypertension. 62, 6, p. 1090-1097 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels

    Krzystanek, K., Rasmussen, Hanne Borger, Grunnet, Morten, Staub, O., Olesen, Søren-Peter, Abriel, H. & Jespersen, Thomas, 2012, In: Heart Rhythm. 9, 3, p. 440-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Development of heart failure is independent of K+ channel-interacting protein 2 expression

    Speerschneider, T., Grubb, Søren, Metoska, A., Olesen, Søren-Peter, Callø, Kirstine & Thomsen, Morten Bækgaard, 1 Dec 2013, In: Journal of Physiology. 591, 23, p. 5923-37 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle

    Callø, Kirstine, Soltysinska, E., Jespersen, Thomas, Lundby, Alicia, Antzelevitch, C., Olesen, Søren-Peter & Cordeiro, J. M., 2009, In: Journal of Molecular and Cellular Cardiology. 48, 1, p. 191-200 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Differential expression of hERG1 channel isoforms reproduces properties of native I(Kr) and modulates cardiac action potential characteristics

    Larsen, A. P. & Olesen, Søren-Peter, 2010, In: P L o S One. 5, 2, p. e9021

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Effect of beta-adrenoceptor blockers on human ether-a-go-go-related gene (HERG) potassium channels.

    Dupuis, D. S., Klærke, Dan Arne & Olesen, Søren-Peter, 2005, In: Basic & Clinical Pharmacology & Toxicology. 96, 2, p. 123-30 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Effects of potassium channel openers in the isolated perfused hypokalaemic murine heart

    Killeen, M. J., Thomas, G., Olesen, Søren-Peter, Demnitz, J., Stokoe, K. S., Grace, A. A. & Huang, C. L. H., 2008, In: Acta Physiologica (Print Edition). 193, 1, p. 25-36 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Extracellular potassium inhibits Kv7.1 potassium channels by stabilizing an inactivated state

    Larsen, A. P., Steffensen, Annette Buur, Grunnet, Morten & Olesen, Søren-Peter, 2011, In: Biophysical Journal. 101, 4, p. 818-27 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Familial Aggregation of Lone Atrial Fibrillation in Young Persons

    Oyen, N., Ranthe, M. F., Carstensen, L., Boyd, H. A., Olesen, M. S., Olesen, Søren-Peter, Wohlfahrt, J. & Melbye, M., 2012, In: Journal of the American College of Cardiology. 60, 10, p. 917-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Forskeren i samfundet: Forskningspolitisk årsmøde 2008

    Kærgård, Niels, Harder, Peter, Bache, C., Flensted-Jensen, M., Koch, Lene, Olesen, Søren-Peter & Sand-Jensen, Kaj, 2008, Det Kongelige Danske Videnskabernes Selskab. 42 p.

    Research output: Book/Report › Book › Communication

  51. Published

    Forskning skal ikke gøre ledelsen glad

    Harder, Peter, Bache, C., Flensted-Jensen, M., Koch, Lene, Olesen, Søren-Peter & Sand-Jensen, Kaj, 11 Feb 2009, In: Universitetsavisen.

    Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication

  52. Published

    Forsknings- og ytringsfriheden på universiteterne: forskningspolitisk årsmøde 2007

    Kærgård, Niels, Bache, C., Flensted-Jensen, M., Harder, Peter, Olesen, Søren-Peter & Wewer, Ulla M., 2007, København: Det Kongelige Danske Videnskabernes Selskab.

    Research output: Book/Report › Book › Communication

  53. Published

    Frequency-dependent modulation of KCNQ1 and HERG1 potassium channels.

    Diness, T. G., Hansen, R. S., Olesen, Søren-Peter & Grunnet, Morten, 2006, In: Biochemical and Biophysical Research Communications. 343, 4, p. 1224-33 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Functional assessment of compound mutations in the KCNQ1 and KCNH2 genes associated with long QT syndrome.

    Grunnet, Morten, Behr, E. R., Callø, Kirstine, Hofman-Bang, J., Till, J., Christiansen, M., McKenna, W. J., Olesen, Søren-Peter & Schmitt, Nicole, 2005, In: Heart Rhythm. 2, 11, p. 1238-49 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Functional characterization of a cloned human intermediate-conductance Ca2+-activated K+ channel

    Jørgensen, T. D., Jensen, B. S., Strøbæk, D., Christofersen, P., Olesen, Søren-Peter & Ahring, B. K., 1999, In: Annals of the New York Academy of Sciences. 868, p. 423-426

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Functional consequences of genetic variation in sodium channel modifiers in early onset lone atrial fibrillation

    Denti, F., Paludan-Müller, Christian, Olesen, Søren-Peter, Haunsø, Stig, Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Bentzen, Bo Hjorth & Schmitt, Nicole, Mar 2018, In: Personalized Medicine. 15, 2, p. 93-102 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Functional coupling between heterologously expressed dopamine D(2) receptors and KCNQ channels.

    Ljungstrom, T., Grunnet, Morten, Jensen, B. S. & Olesen, Søren-Peter, 2003, In: Pflügers Archiv: European Journal of Physiology. 446, 6, p. 684-94 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Functional properties of human neuronal Kv11 channels

    Einarsen, K., Callø, Kirstine, Grunnet, Morten, Olesen, Søren-Peter & Schmitt, Nicole, 2009, In: Pflügers Archiv: European Journal of Physiology. 458, 4, p. 689-700 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone

    Jepps, Thomas Andrew Qvistgaard, Carr, G., Lundegaard, Pia Rengtved, Olesen, Søren-Peter & Greenwood, I. A., 15 Dec 2015, In: Journal of Physiology. 593, 24, p. 5325-40 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization

    Liang, B., Nissen, J. D., Laursen, M., Wang, X., Skibsbye, L., Hearing, M. C., Andersen, M. N., Rasmussen, Hanne Borger, Wickman, K., Grunnet, Morten, Olesen, Søren-Peter & Jespersen, Thomas, 1 Jan 2014, In: Cardiovascular Research. 101, 1, p. 175-84 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology

    Wang, X., Liang, B., Skibsbye, L., Olesen, Søren-Peter, Grunnet, Morten & Jespersen, Thomas, Aug 2013, In: Journal of Cardiovascular Pharmacology. 62, 2, p. 192-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Gain-of-function mutations in potassium channel subunit KCNE2 associated with early-onset lone atrial fibrillation

    Nielsen, J. B., Bentzen, Bo Hjorth, Olesen, Morten Steen Salling, David, J., Olesen, Søren-Peter, Haunsø, Stig, Svendsen, Jesper Hastrup & Schmitt, Nicole, Apr 2014, In: Biomarkers in Medicine. 8, 4, p. 557-570 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation

    Christophersen, I. E., Olesen, M. S., Liang, B., Andersen, M. N., Larsen, A. P., Nielsen, J. B., Haunsø, Stig, Olesen, Søren-Peter, Tveit, A., Svendsen, Jesper Hastrup & Schmitt, Nicole, 21 Dec 2012, In: European Heart Journal.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis

    Liang, B., Soka, M., Christensen, Alex Hørby, Olesen, Morten Steen Salling, Larsen, A. P., Knop, Filip Krag, Wang, F., Nielsen, J. B., Andersen, M. N., Humphreys, D., Mann, S. A., Huttner, I. G., Vandenberg, J. I., Svendsen, Jesper Hastrup, Haunsø, Stig, Preiss, T., Seebohm, G., Olesen, Søren-Peter, Schmitt, Nicole & Fatkin, D., 27 Dec 2013, In: Journal of Molecular and Cellular Cardiology. 67, p. 69-76 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    High Prevalence of Long QT Syndrome Associated SCN5A Variants in Patients with Early-Onset Lone Atrial Fibrillation

    Olesen, M. S., Yuan, L., Liang, B., Holst, A. G., Nielsen, N., Nielsen, J. B., Hedley, P. L., Christiansen, M., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole, Jespersen, Thomas & Svendsen, Jesper Hastrup, 2012, In: Circulation: Cardiovascular Genetics. 5, 4, p. 450-459 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    High throughput electrophysiology: new perspectives for ion channel drug discovery.

    Willumsen, N. J., Bech, M., Olesen, Søren-Peter, Jensen, B. S., Korsgaard, M. P. G. & Christophersen, P., 2003, In: Receptors and Channels. 9, 1, p. 3-12 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Hydralazine-induced vasodilation involves opening of high conductan Ca2+-activated K+ channels

    Bang, L., Nielsen-Kudsk, J. E., Gruhn, N., Trautner, S., Theilgaard, S. A., Olesen, Søren-Peter, Boesgaard, S. & Aldershvile, J., 1998, In: European Journal of Pharmacology. 361(1), p. 43-49

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Hypoosmotic cell swelling as a novel mechanism for modulation of cloned HCN2 channels.

    Callø, Kirstine, Elmedyb, P., Olesen, Søren-Peter, Jorgensen, N. K. & Grunnet, Morten, 2005, In: Biophysical Journal. 89, 3, p. 2159-69 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    IKs Gain- and Loss-of-Function In Early-Onset Lone Atrial Fibrillation

    Steffensen, Annette Buur, Refsgaard, L., Andersen, M. N., Vallet, C., Mujezinovic, A., Haunsø, Stig, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Olesen, Morten Steen Salling & Schmitt, Nicole, 2015, In: Journal of Cardiovascular Electrophysiology. 26, 7, p. 715-23 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Identification of a Kir3.4 Mutation in Congenital Long QT Syndrome

    Yang, Y., Yang, Y., Liang, B., Liu, J., Li, J., Grunnet, M., Olesen, S-P., Rasmussen, H. B., Ellinor, P. T., Gao, L., Lin, X., Li, L., Wang, L., Xiao, J., Liu, Y., Liu, Y., Zhang, S., Liang, D., Peng, L., Jespersen, T. & 1 others, Chen, Y., 2010, In: American Journal of Human Genetics. 86, 6, p. 872-80 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Identification of a novel voltage-gated Na+ channel rNav 1.5a in the rat hippocampal progenitor stem cell line HiB5

    Korsgaard, M., Grunnet, Morten, Christophersen, P., Ahring, P. K. & Olesen, Søren-Peter, 2001, In: Pflügers Archiv: European Journal of Physiology. 443, p. 18-30

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    In vivo effects of the IKr agonist NS3623 on cardiac electrophysiology of the guinea pig.

    Hansen, R. S., Olesen, Søren-Peter, Rønn, L. C. B. & Grunnet, Morten, 2008, In: Journal of Cardiovascular Pharmacology. 52, 1, p. 35-41 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Inactivation as a new regulatory mechanism for neuronal Kv7 channels.

    Jensen, H. S., Grunnet, Morten & Olesen, Søren-Peter, 2007, In: Biophysical Journal. 92, 8, p. 2747-56 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Inhibition of T cell proliferation by selective block of Ca(2+)-activated K(+) channels

    Jensen, B. S., Ødum, Niels, Jorgensen, N. K., Christophersen, P. & Olesen, Søren-Peter, 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, 19, p. 10917-21 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Inhibition of T cell proliferation by selective block of Ca2+-activated K+ channels

    Jensen, B. S., Ødum, Niels, Jørgensen, N. K., Christophersen, P. & Olesen, Søren-Peter, 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, p. 10917-10921

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Inhibition of the human intermediate-conductance, Ca2+-activated K+ channel by intracellular acidification

    Pedersen, K. A., Jørgensen, N. K., Jensen, B. S. & Olesen, Søren-Peter, 2000, In: Pflügers Archiv: European Journal of Physiology. 440(1), p. 153-156

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    K(Ca)3.1 channel downregulation and impaired endothelium-derived hyperpolarization-type relaxation in pulmonary arteries from chronically hypoxic rats

    Kroigaard, C., Kudryavtseva, O., Dalsgaard, T., Wandall-Frostholm, C., Olesen, Søren-Peter & Simonsen, U., Apr 2013, In: Experimental Physiology. 98, 4, p. 957-69 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    K(v)7 channels: Function, pharmacology and channel modulators

    Dalby-Brown, W., Hansen, H. H., Korsgaard, M. P. G., Mirza, N. & Olesen, Søren-Peter, 2006, In: Current Topics in Medicinal Chemistry. 6, 10, p. 999-1023 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    KCNE3 is an inhibitory subunit of the Kv4.3 potassium channel.

    Lundby, Alicia & Olesen, Søren-Peter, 2006, In: Biochemical and Biophysical Research Communications. 346, 3, p. 958-67 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    KCNE3 mutation V17M identified in a patient with lone atrial fibrillation.

    Lundby, Alicia, Ravn, L. S., Svendsen, J. H., Hauns, S., Olesen, Søren-Peter & Schmitt, Nicole, 2008, In: Cellular Physiology and Biochemistry. 21, 1-3, p. 47-54 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.

    Grunnet, Morten, Rasmussen, H. B., Hay-Schmidt, Anders, Rosenstierne, M., Klærke, Dan Arne, Olesen, Søren-Peter & Jespersen, Thomas, 2003, In: Biophysical Journal. 85, 3, p. 1525-37 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    KCNE4 is an inhibitory subunit to the KCNQ1 channel.

    Grunnet, Morten, Jespersen, Thomas, Rasmussen, Hanne Borger, Ljungstrøm, T., Jorgensen, N. K., Olesen, Søren-Peter & Klærke, Dan Arne, 2002, In: Journal of Physiology. 542, Pt 1, p. 119-30 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current.

    Angelo, K., Jespersen, Thomas, Grunnet, Morten, Nielsen, Morten Schak, Klærke, Dan Arne & Olesen, Søren-Peter, 2002, In: Biophysical Journal. 83, 4, p. 1997-2006 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    KCNMA1 encoded cardiac BK channels afford protection against ischemia-reperfusion injury

    Soltysinska, E., Bentzen, B. H., Barthmes, M., Hattel, H., Thrush, A. B., Harper, M-E., Qvortrup, K., Larsen, F. J., Schiffer, T. A., Losa-Reyna, J., Straubinger, J., Kniess, A., Thomsen, M. B., Brüggemann, A., Fenske, S., Biel, M., Ruth, P., Wahl-Schott, C., Boushel, R. C., Olesen, S-P. & 1 others, Lukowski, R., 2014, In: PLOS ONE. 9, 7, p. 1-12 12 p., e103402.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    KCNQ1 channels sense small changes in cell volume.

    Grunnet, Morten, Jespersen, Thomas, MacAulay, Nanna, Jørgensen, N. K., Schmitt, Nicole, Pongs, O., Olesen, Søren-Peter & Klærke, Dan Arne, 2003, In: Journal of Physiology. 549, Pt 2, p. 419-27 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval.

    Lundby, Alicia, Ravn, L. S., Svendsen, Jesper Hastrup, Olesen, Søren-Peter & Schmitt, Nicole, 2007, In: Heart Rhythm. 4, 12, p. 1532-41 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    KCNQ4 channel activation by BMS204352 and retigabine

    Schrøder, R. L., Strøbaek, D., Christophersen, P., Jensen Skanning, B. & Olesen, Søren-Peter, 2001, In: Neuropharmacology. 40, p. 888-898

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    KCNQ4 channels expressed in mammalian cells: Functional characteristics and pharmacology

    Søgaard, R., Ljungstrøm, T., Pedersen, K. A., Olesen, Søren-Peter & Jensen Skanning, B., 2001, In: American Journal of Physiology: Cell Physiology. 280, p. C859-C866

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts

    Laursen, M., Grunnet, Morten, Olesen, Søren-Peter, Jespersen, Thomas & Mow, T., 2012, In: Journal of Pharmacological and Toxicological Methods. 64, 2, p. 134-44 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Kv7.1 surface expression is regulated by epithelial cell polarization

    Andersen, M. N., Olesen, Søren-Peter & Rasmussen, Hanne Borger, 2011, In: American Journal of Physiology: Cell Physiology. 300, 4, p. C814-24

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Kvalitet og styring i fremtidens universiteter - Ejerskab, ledelseskultur og de faktiske følger af universitetsloven: Forskningspolitisk årsmøde 2009

    Harder, Peter, Bache, C., Flensted-Jensen, M., Koch, Lene, Olesen, Søren-Peter & Sand-Jensen, Kaj, 2009, 78 p. Det Kongelige Danske Videnskabernes Selskab.

    Research output: Other contribution › Communication

  92. Published

    Live Imaging of Kv7.2/7.3 Cell Surface Dynamics at the Axon Initial Segment: High Steady-State Stability and Calpain-Dependent Excitotoxic Downregulation Revealed.

    Benned-Jensen, T., Christensen, R. K., Denti, F., Perrier, Jean-Francois Marie, Rasmussen, Hanne Borger & Olesen, Søren-Peter, 2016, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 36, 7, p. 2261-2266

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Loss of K+ currents in heart failure is accentuated in KChIP2 deficient mice

    Grubb, Søren, Speerschneider, T., Occhipinti, D., Fiset, C., Olesen, Søren-Peter, Thomsen, Morten Bækgaard & Callø, Kirstine, 2014, In: Journal of Cardiovascular Electrophysiology. 25, 8, p. 896-904 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Magnetocardiography on an isolated animal heart with a room-temperature optically pumped magnetometer

    Jensen, K., Skarsfeldt, M. A., Stærkind, Hans, Arnbak, J., Balabas, M. V., Olesen, Søren-Peter, Bentzen, Bo Hjorth & Polzik, Eugene Simon, 1 Nov 2018, In: Scientific Reports. 8, 9 p., 16218.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Mechanism of action of NS1643, a novel hERG channel activator

    Casis, O., Olesen, Søren-Peter & Sanguinetti, M. C., 2006, In: Molecular Pharmacology. 69, p. 658-665

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Mechanism of action of a novel human ether-a-go-go-related gene channel activator.

    Casis, O., Olesen, Søren-Peter & Sanguinetti, M. C., 2005, In: Molecular Pharmacology. 69, 2, p. 658-65 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing

    Quinn, T. A., Granite, S., Allessie, M. A., Antzelevitch, C., Bollensdorff, C., Bub, G., Burton, R. A. B., Cerbai, E., Chen, P. S., Delmar, M., Difrancesco, D., Earm, Y. E., Efimov, I. R., Egger, M., Entcheva, E., Fink, M., Fischmeister, R., Franz, M. R., Garny, A., Giles, W. R. & 40 others, Hannes, T., Harding, S. E., Hunter, P. J., Iribe, G., Jalife, J., Johnson, C. R., Kass, R. S., Kodama, I., Koren, G., Lord, P., Markhasin, V. S., Matsuoka, S., McCulloch, A. D., Mirams, G. R., Morley, G. E., Nattel, S., Noble, D., Olesen, Søren-Peter, Panfilov, A. V., Trayanova, N. A., Ravens, U., Richard, S., Rosenbaum, D. S., Rudy, Y., Sachs, F., Sachse, F. B., Saint, D. A., Schotten, U., Solovyova, O., Taggart, P., Tung, L., Varró, A., Volders, P. G., Wang, K., Weiss, J. N., Wettwer, E., White, E., Wilders, R., Winslow, R. L. & Kohl, P., 2011, In: Progress in Biophysics & Molecular Biology. 107, 1, p. 4-10 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Modulation of ERG channels by XE991.

    Elmedyb, P., Callø, Kirstine, Schmitt, Nicole, Hansen, R. S., Grunnet, Morten & Olesen, Søren-Peter, 2007, In: Basic & Clinical Pharmacology & Toxicology. 100, 5, p. 316-22 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Modulation of KCNQ4 channel activity by changes in cell volume.

    Hougaard, C., Klærke, Dan Arne, Hoffmann, E. K., Olesen, Søren-Peter & Jorgensen, N. K., 2004, In: BBA General Subjects. 1660, 1-2, p. 1-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Modulation of the KCNQ4 potassium channel by changes in cell volume

    Hougaard, C., Klærke, Dan Arne, Olesen, Søren-Peter, Hoffmann, E. K. & Jørgensen, N. K., 2004, In: Acta Physiologica (Print Edition). A45-A163, p. A64-A65

    Research output: Contribution to journal › Conference abstract in journal › Research

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