Signe Mathiasen

Signe Mathiasen

Assistant Professor

Member of:


    1. 2021
    2. Single-molecule FRET imaging of GPCR dimers in living cells

      Asher, W. B., Geggier, P., Holsey, M. D., Gilmore, G. T., Pati, A. K., Meszaros, J., Terry, D. S., Mathiasen, Signe, Kaliszewski, M. J., McCauley, M. D., Govindaraju, A., Zhou, Z., Harikumar, K. G., Jaqaman, K., Miller, L. J., Smith, A. W., Blanchard, S. C. & Javitch, J. A., 2021, In: Nature Methods. 18, 4, p. 397-405 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    3. 2020
    4. G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3

      Mathiasen, Signe, Palmisano, T., Perry, N. A., Stoveken, H. M., Vizurraga, A., McEwen, D. P., Okashah, N., Langenhan, T., Inoue, A., Lambert, N. A., Tall, G. G. & Javitch, J. A., Dec 2020, In: Nature Chemical Biology. 16, 12, p. 1343–1350

      Research output: Contribution to journalJournal articlepeer-review

    5. Agonist-induced formation of unproductive receptor-G12 complexes

      Okashah, N., Wright, S. C., Kawakami, K., Mathiasen, Signe, Zhou, J., Lu, S., Javitch, J. A., Inoue, A., Bouvier, M. & Lambert, N. A., 1 Sep 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 35, p. 21723-21730 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    6. Published

      Novel Fluorescent Ligands Enable Single-Molecule Localization Microscopy of the Dopamine Transporter

      Guthrie, D. A., Klein Herenbrink, Carmen, Lycas, M. D., Ku, T., Bonifazi, A., Devree, B. T., Mathiasen, Signe, Javitch, J. A., Grimm, J. B., Lavis, L., Gether, Ulrik & Newman, A. H., 2020, In: ACS Chemical Neuroscience. 11, 20, p. 3288-3300 13 p.

      Research output: Contribution to journalJournal articlepeer-review

    7. 2018
    8. Published

      Single Proteoliposome High-Content Analysis Reveals Differences in the Homo-Oligomerization of GPCRs

      Walsh, S. M., Mathiasen, Signe, Christensen, S. M., Fay, J. F., King, C., Provasi, D., Borrero, E., Rasmussen, Søren Gøgsig Faarup, Fung, J. J., Filizola, M., Hristova, K., Kobilka, B., Farrens, D. L. & Stamou, Dimitrios, 2018, In: Biophysical Journal. 115, 2, p. 300-312 13 p.

      Research output: Contribution to journalJournal articlepeer-review

    9. 2017
    10. Published

      Extreme vetting of dopamine receptor oligomerization

      Asher, W. B., Mathiasen, Signe, Holsey, M. D., Grinnell, S. G., Lambert, N. A. & Javitch, J. A., 2017, Receptors. Humana Press, p. 99-127 29 p. (Receptors, Vol. 33).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    11. Published

      Single-molecule analysis of ligand efficacy in β2AR-G-protein activation

      Gregorio, G. G., Masureel, M., Hilger, D., Terry, D. S., Juette, M., Zhao, H., Zhou, Z., Perez-Aguilar, J. M., Hauge, M., Mathiasen, Signe, Javitch, J. A., Weinstein, H., Kobilka, B. K. & Blanchard, S. C., 2017, In: Nature. 547, 7661, p. 68–73

      Research output: Contribution to journalJournal articlepeer-review

    12. 2016
    13. Published

      Electronic tuning of self-healing fluorophores for live-cell and single-molecule imaging

      Zheng, Q., Jockusch, S., Zhou, Z., Altman, R. B., Zhao, H., Asher, W., Holsey, M., Mathiasen, Signe, Geggier, P., Javitch, J. A. & Blanchard, S. C., 2016, In: Chemical Science. 8, 1, p. 755-762 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    14. 2015
    15. Published

      Impact of PI(3,4,5)P3-Mediated beta-Arrestin-1 Recruitment on Structure of Asymmetric Lipid Bilayers: Biophysical Society Annual Meeting. Baltimore, Maryland, Febr. 7-11 2015

      Nzulumike, A. N. O., Mathiasen, Signe, Mahoney, J. P., Cardenas Gomez, M., Stamou, Dimitrios & Mortensen, Kell, 7 Feb 2015, In: Biophysical Journal. 108, 2, Suppl., p. 342A-342A

      Research output: Contribution to journalConference abstract in journalpeer-review

    16. Published

      CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature

      Miller, S. E., Mathiasen, Signe, Bright, N. A., Pierre, F., Kelly, B. T., Kladt, N., Schauss, A., Merrifield, C. J., Stamou, Dimitrios, Höning, S. & Owen, D. J., 2015, In: Developmental Cell. 33, 2, p. 163-175 13 p.

      Research output: Contribution to journalJournal articlepeer-review

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