Nils Billestrup

Nils Billestrup

Professor

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    ORCID: 0000-0002-4968-8067

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    1. Published

      Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus

      Christensen, D. P., Dahllöf, M. S., Lundh, M., Rasmussen, D. N., Nielsen, M. D., Billestrup, Nils, Grunnet, L. G. & Mandrup-Poulsen, Thomas, 2011, In: Molecular Medicine. 17, 5-6, p. 378-90 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Human growth hormone binding and stimulation of insulin biosynthesis in cloned rat insulinoma cells

      Billestrup, Nils, 1985, In: Biomedica Biochimica Acta. 44, 1, p. 85-7 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      ID'ing a novel inhibitor of β-cell function, Id1

      Billestrup, Nils, Oct 2011, In: Diabetes. 60, 10, p. 2455-6 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      IL-1 beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells

      Jacobsen, M. L. B., Ronn, S. G., Bruun, C., Larsen, C. M., Eizirik, D. L., Mandrup-Poulsen, Thomas & Billestrup, Nils, 2009, In: Diabetologia. 52, 2, p. 281-288 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      IL-1beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells

      Jacobsen, M. L. B., Rønn, S. G., Bruun, C., Larsen, C. M., Eizirik, D. L., Mandrup-Poulsen, Thomas & Billestrup, Nils, 2008, In: Diabetologia. 52, 2, p. 281-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      IL-1beta-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line

      Petersen, L. G., Størling, Joachim, Heding, P., Li, S., Berezin, V., Saldeen, J., Billestrup, Nils, Bock, E. & Mandrup-Poulsen, Thomas, 2006, In: Diabetologia. 49, 8, p. 1864-75 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Identification and characterization of a pituitary corticotropin-releasing factor binding protein by chemical cross-linking

      Nishimura, E., Billestrup, Nils, Perrin, M. & Vale, W., 25 Sep 1987, In: The Journal of Biological Chemistry. 262, 27, p. 12893-6 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Identification of a growth hormone-responsive STAT5-binding element in the rat insulin 1 gene

      Galsgaard, E. D., Gouilleux, F., Groner, B., Serup, Palle, Billestrup, Nils & Nielsen, Jens Høiriis, Jun 1996, In: Molecular endocrinology (Baltimore, Md.). 10, 6, p. 652-60 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Identification of corticotropin-releasing factor (CRF) target cells and effects of dexamethasone on binding in anterior pituitary using a fluorescent analog of CRF

      Schwartz, J., Billestrup, Nils, Perrin, M., Rivier, J. & Vale, W., Nov 1986, In: Endocrinology. 119, 5, p. 2376-82 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Identification of intracellular domains in the growth hormone receptor involved in signal transduction

      Billestrup, Nils, Allevato, G., Norstedt, G., Møldrup, A. & Nielsen, Jens Høiriis, Jul 1994, In: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 206, 3, p. 205-9 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Identification of phenylalanine 346 in the rat growth hormone receptor as being critical for ligand-mediated internalization and down-regulation

      Allevato, G., Billestrup, Nils, Goujon, L., Galsgaard, E. D., Norstedt, G., Postel-Vinay, M. C., Kelly, P. A. & Nielsen, Jens Høiriis, 21 Jul 1995, In: The Journal of Biological Chemistry. 270, 29, p. 17210-4 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Identification of tyrosine residues in the intracellular domain of the growth hormone receptor required for transcriptional signaling and Stat5 activation

      Hansen, L. H., Wang, X., Kopchick, J. J., Bouchelouche, P., Galsgaard, E. D., Nielsen, Jens Høiriis & Billestrup, Nils, 24 May 1996, In: The Journal of Biological Chemistry. 271, 21, p. 12669-73 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Impact of fasting on growth hormone signaling and action in muscle and fat

      Moller, L., Dalman, L., Norrelund, H., Billestrup, Nils, Frystyk, J., Moller, N. & Jorgensen, J. O. L., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 3, p. 965-72 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Impact of fetal and neonatal environment on beta cell function and development of diabetes

      Nielsen, Jens Høiriis, Haase, T. N., Jaksch, C., Nalla, A., Søstrup, B., Nalla, A. A., Larsen, L., Rasmussen, M., Dalgaard, L. T., Gaarn, L. W., Thams, P., Kofod, H. & Billestrup, Nils, Nov 2014, In: Acta Obstetricia et Gynecologica Scandinavica. 93, 11, p. 1109-22 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Implications for the offspring of circulating factors involved in beta cell adaptation in pregnancy

      Nalla, A., Ringholm, L., Søstrup, B., Højrup, P., Thim, L., Levery, S. B., Vakhrushev, Sergey, Billestrup, Nils, Mathiesen, Elisabeth, Damm, Peter & Nielsen, Jens Høiriis, Nov 2014, In: Acta Obstetricia et Gynecologica Scandinavica. 93, 11, p. 1181-9 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      In-vitro and in-vivo studies supporting the therapeutic potential of ZP3022 in diabetes

      Skarbaliene, J., Rigbolt, K. T., Fosgerau, K. & Billestrup, Nils, 15 Nov 2017, In: European Journal of Pharmacology. 815, p. 181-189 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Inflammatory Cytokines Stimulate Bone Morphogenetic Protein-2 Expression and Release from Pancreatic Beta Cells

      Urizar, A. I., Friberg, J., Christensen, D. P., Christensen, G. L. & Billestrup, Nils, 1 Jan 2016, In: Journal of Interferon & Cytokine Research. 36, 1, p. 20-29

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Inhibition of Nuclear Factor-kappa B or Bax Prevents Endoplasmic Reticulum Stress-But Not Nitric Oxide-Mediated Apoptosis in INS-1E Cells

      Tonnesen, M. F., Grunnet, L. G., Friberg, J., Cardozo, A. K., Billestrup, Nils, Eizirik, D. L., Storling, J. & Mandrup-Poulsen, Thomas, 2009, In: Endocrinology. 150, 9, p. 4094-4103 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Inhibition of beta cell growth and function by bone morphogenetic proteins

      Bruun, C., Christensen, G. L., Jacobsen, M. L. B., Kanstrup, M. B., Jensen, P. R., Fjordvang, H., Mandrup-Poulsen, Thomas & Billestrup, Nils, 27 Sep 2014, In: Diabetologia. 57, 12, p. 2546-54 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells

      Larsen, L., Tonnesen, M., Ronn, S. G., Størling, Joachim, Jørgensen, S., Mascagni, P., Dinarello, C. A., Billestrup, Nils & Mandrup-Poulsen, Thomas, Apr 2007, In: Diabetologia. 50, 4, p. 779-89 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in INS-1E cells

      Tonnesen, M. F., Grunnet, L. G., Friberg, J., Cardozo, A. K., Billestrup, Nils, Eizirik, D. L., Størling, Joachim & Mandrup-Poulsen, Thomas, Sep 2009, In: Endocrinology. 150, 9, p. 4094-103 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Inhibition of somatotroph growth and growth hormone biosynthesis by activin in vitro

      Billestrup, Nils, González-Manchón, C., Potter, E. & Vale, W., Feb 1990, In: Molecular endocrinology (Baltimore, Md.). 4, 2, p. 356-62 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Introduction of exogenous growth hormone receptors augments growth hormone-responsive insulin biosynthesis in rat insulinoma cells

      Billestrup, Nils, Møldrup, A., Serup, Palle, Mathews, L. S., Norstedt, G. & Nielsen, Jens Høiriis, Sep 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 18, p. 7210-4 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1 beta-Induced Apoptosis Associated with Abrogated Myc Expression

      Prause, Michala Cecilie Burstein, Mayer, C. M., Brorsson, C., Frederiksen, K. S., Billestrup, Nils, Størling, Joachim & Mandrup-Poulsen, Thomas, 2016, In: Journal of Diabetes Research. 2016, 15 p., 1312705.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      JNK1 protects against glucolipotoxicity-mediated beta-cell apoptosis

      Prause, Michala Cecilie Burstein, Christensen, D. P., Billestrup, Nils & Mandrup-Poulsen, Thomas, 2014, In: PLOS ONE. 9, 1, p. 1-11 11 p., e87067.

      Research output: Contribution to journal › Journal article › Research › peer-review

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