Nils Billestrup
Professor
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Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection
Christensen, D. P., Gysemans, C., Lundh, M., Dahllöf, M. S., Noesgaard, D., Schmidt, S. F., Mandrup, S., Birkbak, N., Workman, C., Piemonti, L., Blaabjerg, L., Monzani, V., Fossati, G., Mascagni, P., Paraskevas, S., Aikin, R. A., Billestrup, N., Grunnet, L. G., Dinarello, C. A., Mathieu, C. & 1 others, , 6 Jan 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. 1055-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines
Lundh, M., Christensen, D. P., Rasmussen, D. N., Mascagni, P., Dinarello, C. A., Billestrup, Nils, Grunnet, L. G. & Mandrup-Poulsen, Thomas, 1 Dec 2010, In: Diabetologia. 53, 12, p. 2569-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins
Hansen, J. A., Lindberg, K., Hilton, D. J., Nielsen, Jens Høiriis & Billestrup, Nils, Nov 1999, In: Molecular endocrinology (Baltimore, Md.). 13, 11, p. 1832-43 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanism of protein tyrosine phosphatase 1B-mediated inhibition of leptin signalling
Lund, I. K., Hansen, J. A., Andersen, H. S., Møller, N. P. H. & Billestrup, Nils, 1 Apr 2005, In: Journal of Molecular Endocrinology. 34, 2, p. 339-51 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular dissection of the growth hormone receptor. Identification of distinct cytoplasmic domains corresponding to different signaling pathways
Billestrup, Nils, Allevato, G., Møldrup, A., Galsgaard, E. D., Amstrup, J., Hansen, J. A., Svensson, C. & Nielsen, Jens Høiriis, 7 Sep 1995, In: Annals of the New York Academy of Sciences. 766, p. 481-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular mechanism of growth hormone signalling
Billestrup, Nils, Hansen, J. A., Hansen, L. H., Møldrup, A., Galsgaard, E. D. & Nielsen, Jens Høiriis, Apr 1998, In: Endocrine Journal. 45 Suppl, p. S41-5Research output: Contribution to journal › Journal article › Research › peer-review
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Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes
Reinhard, H., Jacobsen, P. K., Lajer, M., Pedersen, N., Billestrup, Nils, Mandrup-Poulsen, Thomas, Parving, H. & Rossing, Peter, 1 Oct 2010, In: Diabetologica. 53, 10, p. 2129-33 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multiple growth hormone-binding proteins are expressed on insulin-producing cells
Møldrup, A., Billestrup, Nils, Thorn, N. A., Lernmark, A. & Nielsen, Jens Høiriis, Aug 1989, In: Molecular endocrinology (Baltimore, Md.). 3, 8, p. 1173-82 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity
Gylvin, T., Nolsøe, R., Hansen, Torben, Nielsen, E. M. D., Bergholdt, R., Karlsen, A. E., Billestrup, Nils, Borch-Johnsen, K., Pedersen, O., Mandrup-Poulsen, Thomas, Nerup, J. & Pociot, Flemming, 1 Jul 2004, In: Diabetologia. 47, 7, p. 1273-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B
Stofega, M. R., Herrington, J., Billestrup, Nils & Carter-Su, C., Sep 2000, In: Molecular endocrinology (Baltimore, Md.). 14, 9, p. 1338-50 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt
Størling, Joachim, Binzer, J., Andersson, A., Züllig, R. A., Tonnesen, M., Knudsen, R. L. P., Spinas, G. A., Sandler, S., Billestrup, Nils & Mandrup-Poulsen, Thomas, 1 Oct 2005, In: Diabetologia. 48, 10, p. 2039-50 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nuclear translocation and retention of growth hormone
Mertani, H. C., Raccurt, M., Abbate, A., Kindblom, J., Törnell, J., Billestrup, Nils, Usson, Y., Morel, G. & Lobie, P. E., Jul 2003, In: Endocrinology. 144, 7, p. 3182-95 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo
Berchtold, L. A., Miani, M., Diep, T. A., Madsen, A. N., Cigliola, V., Colli, M., Miskovic Krivokapic, Jelena, Pociot, Flemming, Eizirik, D. L., Meda, P., Holst, Birgitte, Billestrup, Nils & Storling, J., 2017, In: Molecular and Cellular Endocrinology. 448, p. 108-121 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pituitary adenomas in mice transgenic for growth hormone-releasing hormone
Asa, S. L., Kovacs, K., Stefaneanu, L., Horvath, E., Billestrup, Nils, Gonzalez-Manchon, C. & Vale, W., Nov 1992, In: Endocrinology. 131, 5, p. 2083-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pituitary mammosomatotroph adenomas develop in old mice transgenic for growth hormone-releasing hormone
Asa, S. L., Kovacs, K., Stefaneanu, L., Horvath, E., Billestrup, Nils, Gonzalez-Manchon, C. & Vale, W., Mar 1990, In: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 193, 3, p. 232-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preparation of 125I-protein A usable for up to 10 months in immunoassays
Dyrberg, T. & Billestrup, Nils, 6 Jul 1984, In: Journal of Immunological Methods. 71, 2, p. 193-201 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells
Grunnet, L. G., Aikin, R., Tonnesen, M. F., Paraskevas, S., Blaabjerg, L., Størling, J., Rosenberg, L., Billestrup, Nils, Maysinger, D. & Mandrup-Poulsen, Thomas, 2009, In: Diabetes. 58, 8, p. 1807-15 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proliferation of sorted human and rat beta cells
Parnaud, G., Bosco, D., Berney, T., Pattou, F., Kerr-Conte, J., Donath, M. Y., Bruun, C., Mandrup-Poulsen, Thomas, Billestrup, Nils & Halban, P. A., 2008, In: Diabetologia. 51, 1, p. 91-100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rat insulinoma cells express both a 115-kDa growth hormone receptor and a 95-kDa prolactin receptor structurally related to the hepatic receptors
Møldrup, A., Billestrup, Nils & Nielsen, Jens Høiriis, 25 May 1990, In: The Journal of Biological Chemistry. 265, 15, p. 8686-90 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of Pancreatic Alpha Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) in vitro.
Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p., 27479530 .Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of Pancreatic α-Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) In Vitro
Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of glucose transport and c-fos and egr-1 expression in cells with mutated or endogenous growth hormone receptors
Gong, T. W., Meyer, D. J., Liao, J., Hodge, C. L., Campbell, G. S., Wang, X., Billestrup, Nils, Carter-Su, C. & Schwartz, J., Apr 1998, In: Endocrinology. 139, 4, p. 1863-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of pancreatic beta-cell mass and proliferation by SOCS-3
Lindberg, K., Rønn, S. G., Tornehave, D., Richter, H., Hansen, J. A., Rømer, J., Jackerott, M. & Billestrup, Nils, Oct 2005, In: Journal of Molecular Endocrinology. 35, 2, p. 231-43 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Requirement of tyrosine residues 333 and 338 of the growth hormone (GH) receptor for selected GH-stimulated function
Lobie, P. E., Allevato, G., Norstedt, G., Billestrup, Nils & Nielsen, Jens Høiriis, 15 Sep 1995, In: The Journal of Biological Chemistry. 270, 37, p. 21745-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SOCS-3 is involved in the downregulation of the acute insulin-like effects of growth hormone in rat adipocytes by inhibition of Jak2/IRS-1 signaling
Ridderstråle, M., Amstrup, J., Hilton, D. J., Billestrup, Nils & Tornqvist, H., Mar 2003, In: Hormone and Metabolic Research. Supplement. 35, 3, p. 169-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 15311848
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JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1 beta-Induced Apoptosis Associated with Abrogated Myc Expression
Research output: Contribution to journal › Journal article › Research › peer-review
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38
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Butyrate protects pancreatic beta cells from cytokine-induced dysfunction
Research output: Contribution to journal › Journal article › Research › peer-review
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32
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Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published