Julien Ochala

Julien Ochala

Associate Professor - Promotion Programme

Member of:


    1. 2023
    2. Published

      A rational approach to selective targeting of skeletal myosin

      Katarina Antonovic, A., Ochala, Julien & Fornili, A., 2023, In: Biophysical Journal. 122, 3S1, p. 117a

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Abnormal myosin post-translational modifications and ATP turnover time associated with human congenital myopathy-related RYR1 mutations

      Sonne, A., Antonovic, A. K., Thomsen, Elise Julie Melhedegaard, Akter, F., Andersen, J. L., Jungbluth, H., Witting, N., Vissing, John, Zanoteli, E., Fornili, A. & Ochala, Julien, 2023, In: Acta Physiologica. 239, 2, 14 p., e14035.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Activation of eIF4E-binding-protein-1 rescues mTORC1-induced sarcopenia by expanding lysosomal degradation capacity

      Crombie, E. M., Kim, S., Adamson, S., Dong, H., Lu, T. C., Wu, Y., Wu, Y., Levy, Y., Stimple, N., Lam, W. M. R., Hey, H. W. D., Withers, D. J., Hsu, A. L., Bay, B. H., Ochala, Julien & Tsai, S. Y., 2023, In: Journal of Cachexia, Sarcopenia and Muscle. 14, p. 198–213

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Binding pocket dynamics along the recovery stroke of human β-cardiac myosin

      Akter, F., Ochala, Julien & Fornili, A., 2023, In: PLOS Computational Biology. 19, 5, 14 p., e1011099.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle

      Negoita, F., Addinsall, A. B., Hellberg, K., Bringas, C. F., Hafen, P. S., Sermersheim, T. J., Agerholm, M., Lewis, C. T. A., Ahwazi, D., Ling, N. X. Y., Larsen, J. K., Deshmukh, A. S., Hossain, M. A., Oakhill, J. S., Ochala, J., Brault, J. J., Sankar, U., Drewry, D. H., Scott, J. W., Witczak, C. A. & 1 others, Sakamoto, Kei, 2023, In: Molecular Metabolism. 75, 14 p., 101761.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Comparative study of binding pocket structure and dynamics in cardiac and skeletal myosin

      Antonovic, A. K., Ochala, Julien & Fornili, A., 2023, In: Biophysical Journal. 122, 1, p. 54-62

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Human skeletal myopathy myosin mutations disrupt myosin head sequestration

      Carrington, G., Hau, A., Kosta, S., Dugdale, H. F., Muntoni, F., D’Amico, A., Van den Bergh, P., Romero, N. B., Malfatti, E., Vilchez, J. J., Oldfors, A., Pajusalu, S., Õunap, K., Giralt-Pujol, M., Zanoteli, E., Campbell, K. S., Iwamoto, H., Peckham, M. & Ochala, Julien, 2023, In: JCI insight. 8, 21, p. 1-19 e172322.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Myosin Heavy Chain as a Novel Key Modulator of Striated Muscle Resting State

      Lewis, Christopher T.A. & Ochala, Julien, 2023, In: Physiology. 38, 1, p. 3-9

      Research output: Contribution to journalReviewResearchpeer-review

    10. Published

      Myosin post-translational modifications and function in the presence of myopathy-linked truncating MYH2 mutations

      Sonne, A., Peverelli, L., Hernandez-Lain, A., Domínguez-González, C., Andersen, J. L., Milone, M., Beggs, A. H. & Ochala, Julien, 2023, In: American journal of physiology. Cell physiology. 324, 3, p. C769–C776 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption

      Lewis, C. T. A., Tabrizian, L., Nielsen, J., Laitila, J., Beck, T. N., Olsen, M. S., Ognjanovic, M. M., Aagaard, P., Hokken, R., Laugesen, S., Ingersen, A., Andersen, J. L., Soendenbroe, C., Helge, J. W., Dela, F., Larsen, S., Sahl, R. E., Rømer, T., Hansen, M. T., Frandsen, J. & 2 others, Suetta, Charlotte & Ochala, Julien, 2023, In: The Journal of general physiology. 155, 7, 8 p., e202213268.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Predominant myosin superrelaxed state in canine myocardium with naturally occurring dilated cardiomyopathy

      Ochala, Julien, Lewis, Christopher T.A. , Beck, T., Iwamoto, H., Hessel, A. L., Campbell, K. S. & Pyle, W. G., 2023, In: American journal of physiology. Heart and circulatory physiology. 325, 3, p. H585-H591

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Revisiting specific force loss in human permeabilized single skeletal muscle fibers obtained from older individuals

      Kalakoutis, M., Pollock, R. D., Lazarus, N. R., Atkinson, R. A., George, M., Berber, O., Woledge, R. C., Ochala, Julien & Harridge, S. D. R., 2023, In: American journal of physiology. Cell physiology. 325, 1, p. C172-C185

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Ryanodine receptor type 1 content decrease-induced endoplasmic reticulum stress is a hallmark of myopathies

      Vidal, J., Fernandez, E. A., Wohlwend, M., Laurila, P. P., Lopez-Mejia, A., Ochala, Julien, Lobrinus, A. J., Kayser, B., Lopez-Mejia, I. C., Place, N. & Zanou, N., 2023, In: Journal of Cachexia, Sarcopenia and Muscle. 14, 6, p. 2882-2897

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      The dawn of the functional genomics era in muscle physiology

      Seaborne, Robert Arthur Elliston & Ochala, Julien, 15 Apr 2023, In: Journal of Physiology. 601, 8, p. 1343-1352

      Research output: Contribution to journalReviewResearchpeer-review

    16. Published

      Slow myosin heavy chain 1 is required for slow myofibril and muscle fibre growth but not for myofibril initiation

      Hau, H. T. A., Kelu, J. J., Ochala, Julien & Hughes, S. M., Jul 2023, In: Developmental Biology. 499, p. 47-58 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 240294914