Jens Juul Holst

Jens Juul Holst

Professor


  1. 2015
  2. Published

    Post-surgical effects of Roux-En-Y gastric bypass on glucose homeostasis, intestinal morphology and L-cells in obese Göttingen minipigs

    Barkholt, P., Vegge, A., Clausen, T. R., Birck, M. M., Fels, J. J., Støckel, M., Gögenur, Ismail, Eriksen, Thomas, Holst, Jens Juul, Hansen, Axel Kornerup, Thymann, Thomas, Jelsing, J., Sangild, Per Torp & Raun, K., 2015, In: Journal of Obesity and Bariatrics. 1, 1, 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    In vivo efficacy of HD0471953: A novel GPR119 agonist for the treatment of type 2 diabetes mellitus

    'T Hart, L. M., Fritsche, A., Nijpels, G., Van Leeuwen, N., Donnelly, L. A., Dekker, J. M., Alssema, M., Fadista, J., Carlotti, F., Gjesing, A. P., Palmer, C. N., Van Haeften, T. W., Herzberg-Schäfer, S. A., Simonis-Bik, A. M., Houwing-Duistermaat, J. J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., MacHicao, F. & 14 others, Willemsen, G., Heine, R. J., Kramer, M. H., Holst, Jens Juul, De Koning, E. J., Häring, H. U., Pedersen, O., Groop, L., De Geus, E. J., Slagboom, P. E., Boomsma, D. I., Eekhoff, E. M., Pearson, E. R. & Diamant, M., 1 Feb 2015, In: Diabetes Technology & Therapeutics. 17, p. S131-S133

    Research output: Contribution to journalComment/debateResearchpeer-review

  4. Published

    Restoration of the insulinotropic effect of glucose-dependent insulinotropic polypeptide contributes to the antidiabetic effect of dipeptidyl peptidase-4 inhibitors

    Aaboe, K., Akram, S., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jan 2015, In: Diabetes, Obesity and Metabolism. 17, 1, p. 74-81 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Stability of glucagon-like peptide-1 and glucagon in human plasma

    Albrechtsen, Nicolai Jacob Wewer, Bak, M. J., Hartmann, Bolette, Christensen, L. W., Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 16 Jan 2015, In: Endocrine Connections. 4, 1, p. 50-57 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Renal Extraction and Acute Effects of Glucagon-like peptide-1 on Central and Renal Hemodynamics in Healthy Men

    Asmar, A., Simonsen, L., Asmar, M., Madsbad, Sten, Holst, Jens Juul, Frandsen, E., Moro, C., Jonassen, Thomas & Bülow, J., 15 Apr 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 8, p. E641-E649 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Effect of Oxyntomodulin, Glucagon, GLP-1 and Combined Glucagon +GLP-1 Infusion on Food Intake, Appetite and Resting Energy Expenditure

    Bagger, J. I., Holst, Jens Juul, Hartmann, Bolette, Andersen, B., Knop, Filip Krag & Vilsbøll, T., 2015, In: The Journal of Clinical Endocrinology & Metabolism. 100, 12, p. 4541–4552 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Four weeks supplementation with Lactobacillus paracasei subsp. paracasei L. casei W8® shows modest effect on triacylglycerol in young healthy adults

    Bjerg, A. T., Kristensen, M. B., Ritz, C., Stark, K. D., Holst, Jens Juul, Leser, T. D., Wellejus, A. & Astrup, A., 2015, In: Beneficial Microbes. 6, 1, p. 29-39 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Dairy proteins, dairy lipids, and postprandial lipemia in persons with abdominal obesity (DairyHealth): a 12-wk, randomized, parallel-controlled, double-blinded, diet intervention study

    Bohl, M., Bjørnshave, A., Rasmussen, K. V., Schioldan, A. G., Amer, B., Larsen, M. K., Dalsgaard, T. K., Holst, Jens Juul, Herrmann, A., O'Neill, S., O'Driscoll, L., Afman, L., Jensen, E., Christensen, M. M., Gregersen, S. & Hermansen, K., Apr 2015, In: The American Journal of Clinical Nutrition. 101, 4, p. 870-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Accelerated protein digestion and amino acid absorption after Roux-en-Y gastric bypass

    Bojsen-Møller, A. K., Jacobsen, S. H., Dirksen, C., Jørgensen, N. B., Reitelseder, S., Jensen, J. B., Kristiansen, V. B., Holst, Jens Juul, van Hall, Gerrit & Madsbad, Sten, Sep 2015, In: The American Journal of Clinical Nutrition. 102, 3, p. 600-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein-Coupled Bile Acid Receptors

    Brighton, C. A., Rievaj, J., Kuhre, Rune Ehrenreich, Glass, L. L., Schoonjans, K., Holst, Jens Juul, Gribble, F. M. & Reimann, F., 2015, In: Endocrinology. 156, 11, p. 3961-1370 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Heterogeneity of glucagonomas due to differential processing of proglucagon-derived peptides

    Challis, B. G., Albrechtsen, Nicolai Jacob Wewer, Bansiya, V., Burling, K., Barker, P., Hartmann, Bolette, Gribble, F., O'Rahilly, S., Holst, Jens Juul & Simpson, H. L., 2015, In: Endocrinology, Diabetes & Metabolism Case Reports. 2015, p. 1-7 7 p., 150105.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Vascular, but not luminal, activation of FFAR1 (GPR40) stimulates GLP-1 secretion from isolated perfused rat small intestine

    Christensen, L. W., Kuhre, Rune Ehrenreich, Janus, C., Svendsen, B. & Holst, Jens Juul, 17 Sep 2015, In: Physiological Reports. 3, 9, p. 1-13 13 p., e122551.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Transfer of liraglutide from blood to cerebrospinal fluid is minimal in patients with type 2 diabetes

    Christensen, M., wbf943, wbf943, Hartmann, Bolette, Grevstad, U., Rosenkilde, Mette, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Nov 2015, In: International journal of obesity (2005). 39, 11, p. 1651-1654 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  15. Published

    Glucose-Dependent Insulinotropic Polypeptide Augments Glucagon Responses to Hypoglycemia in Type 1 Diabetes

    Christensen, Mikkel Bring, Calanna, S., wbf943, wbf943, Kristensen, P. L., Rosenkilde, Mette, Faber, Jens, Purrello, F., van Hall, Gerrit, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Jan 2015, In: Diabetes. 64, 1, p. 72-78 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The VGF-Derived Neuropeptide TLQP-21 Shows No Impact on Hormone Secretion in the Isolated Perfused Rat Pancreas

    Christiansen, Charlotte Bayer, Svendsen, B. & Holst, Jens Juul, 20 Jan 2015, In: Hormone and Metabolic Research. 47, 07, p. 537-43 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The Use of Gastrostomy Tube for the Long-Term Remission of Hyperinsulinemic Hypoglycemia After Roux-en-y Gastric Bypass: A Case Report

    Craig, C., Lamendola, C., Holst, Jens Juul, Deacon, Carolyn F. & McLaughlin, T., 2015, In: AACE Clinical Case Reports. 1, 2, p. e84-e87 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Type 2 diabetes mellitus

    DeFronzo, R. A., Ferrannini, E., Groop, L., Henry, R. R., Herman, W. H., Holst, Jens Juul, Hu, F. B., Kahn, C. R., Raz, I., Shulmann, G. I., Simonson, D. C., Testa, M. A. & Weiss, R., 2015, In: Nature Reviews. Disease Primers. 1, 22 p., 15019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Efficacy and safety of the glucagon-like peptide-1 receptor agonist liraglutide added to insulin therapy in poorly regulated patients with type 1 diabetes-a protocol for a randomised, double-blind, placebo-controlled study: The Lira-1 study

    Dejgaard, T. F., Knop, Filip Krag, Tarnow, L., Frandsen, C. S., Hansen, T. S., Almdal, Thomas Peter, Holst, Jens Juul, Madsbad, Sten & Andersen, H. U., 2015, In: B M J Open. 5, 4, p. 1-8 8 p., e007791.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The structure of wheat bread influences the postprandial metabolic response in healthy men

    Eelderink, C., Noort, M. W. J., Sozer, N., Koehorst, M., Holst, Jens Juul, Deacon, Carolyn F., Rehfeld, Jens Frederik, Poutanen, K., Vonk, R. J., Oudhuis, L. & Priebe, M. G., Oct 2015, In: Food & Function. 6, 10, p. 3236-48 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Transcriptional and Functional Characterization of the G Protein-Coupled Receptor Repertoire of Gastric Somatostatin Cells

    Egerod, Kristoffer Lihme, Engelstoft, M. S., Lund, M. L., Grunddal, Kaare Villum, Zhao, M., Barir-Jensen, D., Nygaard, E. B., Petersen, N., Holst, Jens Juul & Schwartz, Thue W., Nov 2015, In: Endocrinology. 156, 11, p. 3909-23 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Reduction of insulinotropic properties of GLP-1 and GIP after glucocorticoid-induced insulin resistance

    Eriksen, M., Jensen, D. H., Tribler, S., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2015, In: Diabetologia. 58, 5, p. 920-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Response to Comment on Færch et al. GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study. Diabetes 2015;64:2513–2525

    Ferch, K., Torekov, Signe Sørensen, Vistisen, D., Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Sandbek, A., Holst, Jens Juul & Jørgensen, M. E., 1 Sep 2015, In: Diabetes. 64, 9, p. e30-e31

    Research output: Contribution to journalComment/debateResearchpeer-review

  24. Published

    Twelve-Week Treatment With Liraglutide as Add-on to Insulin in Normal-Weight Patients With Poorly Controlled Type 1 Diabetes: A Randomized, Placebo-Controlled, Double-Blind Parallel Study

    Frandsen, C. S., Dejgaard, T. F., Holst, Jens Juul, Andersen, H. U., Thorsteinsson, B. & Madsbad, Sten, Dec 2015, In: Diabetes Care. 38, 12, p. 2250-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes

    Fredheim, S., Andersen, M. M., Pörksen, S., Nielsen, L. B., Pipper, C., Hansen, L., Holst, Jens Juul, Thomsen, J., Johannesen, Jesper, Mortensen, H. B. & Svensson, Jannet, 2015, In: Diabetologia. 58, 4, p. 828-34 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Glucagon-Like Peptide-1 (GLP-1) Response to Oral Glucose is Reduced in Pre-diabetes, Screen-detected Type 2 Diabetes and Obesity, and Influenced by Sex: The ADDITION-PRO Study

    Færch, K., Torekov, Signe Sørensen, Vistisen, D., Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Sandbæk, A., Holst, Jens Juul & Jørgensen, M. E., Jul 2015, In: Diabetes. 64, p. 2513-25 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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