Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

Publication year:
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1 - 49 out of 49Page size: 100
  1. 2010
  2. Published

    Treatment of insulin resistance and obesity by stimulating GLP-1 release

    Hansen, Harald S., Diep, T. A., Holst, Jens Juul, Rosenkilde, Mette & Andersen, N. W., 29 Dec 2010, IPC No. A61K 31/23, Patent No. PCT/DK2010/050161, 24 Jun 2010

    Research output: Patent

  3. Published

    Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1

    Migoya, E. M., Bergeron, R., Miller, J. L., Snyder, R. N. K., Tanen, M., Hilliard, D., Weiss, B., Larson, P., Gutierrez, M., Jiang, G., Liu, F., Pryor, K. A., Yao, J., Zhu, L., Holst, J. J., Deacon, C., Herman, G., Thornberry, N., Amatruda, J., Williams-Herman, D. & 2 others, Wagner, J. A. & SinhaRoy, R., 1 Dec 2010, In: Clinical Pharmacology and Therapeutics. 88, 6, p. 801-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Sustained glucagon-like peptide-2 infusion is required for intestinal adaptation, and cessation reverses increased cellularity in rats with intestinal failure

    Koopmann, M. C., Chen, X., Holst, Jens Juul & Ney, D. M., 1 Dec 2010, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 299, 6, p. G1222-30 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A cereal-based evening meal rich in indigestible carbohydrates increases plasma butyrate the next morning

    Nilsson, A. C., Östman, E. M., Knudsen, K. E. B., Holst, Jens Juul & Björck, I. M. E., 1 Nov 2010, In: Journal of Nutrition. 140, 11, p. 1932-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Differential incretin effects of GIP and GLP-1 on gastric emptying, appetite, and insulin-glucose homeostasis

    Edholm, T., Degerblad, M., Grybäck, P., Hilsted, Linda, Holst, Jens Juul, Jacobsson, H., Efendic, S., Schmidt, P. T. & Hellström, P. M., 1 Nov 2010, In: Neurogastroenterology and Motility Online. 22, 11, p. 1191-200, e315 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Kardiale virkninger af glukagonlignende peptid 1

    Holst, Jens Juul, 11 Oct 2010, In: Ugeskrift for Laeger. 172, 41, p. 2821 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Expression of mRNA for proglucagon and glucagon-like peptide-2 (GLP-2) receptor in the ruminant gastrointestinal tract and the influence of energy intake

    Taylor-Edwards, C. C., Burrin, D. G., Matthews, J. C., McLeod, K. R., Holst, Jens Juul & Harmon, D. L., 1 Oct 2010, In: Domestic Animal Endocrinology. 39, 3, p. 181-93 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The intestinotrophic peptide, GLP-2, counteracts the gastrointestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, erlotinib, and cisplatin

    Rasmussen, A. R., Viby, N., Hare, K. J., Hartmann, Bolette, Thim, L., Holst, Jens Juul & Poulsen, Steen Seier, 1 Oct 2010, In: Digestive Diseases and Sciences. 55, 10, p. 2785-96 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Glucagon suppression during OGTT worsens while suppression during IVGTT sustains alongside development of glucose intolerance in patients with chronic pancreatitis

    Knop, Filip Krag, Vilsbøll, Tina, Larsen, S., Madsbad, Sten, Holst, Jens Juul & Krarup, T. M., 24 Sep 2010, In: Regulatory Peptides. 164, 2-3, p. 144-50 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The impact of pancreatic enzyme supplementation on postprandial responses of glucagon-like Peptide-2 in patients with chronic pancreatitis and pancreatic exocrine insufficiency

    Knop, Filip Krag, Vilsbøll, Tina, Lund, A., Krarup, T., Holst, Jens Juul & Hornum, Mads, 6 Sep 2010, In: Journal of the Pancreas. 11, 5, p. 489-91 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Glucose-dependent insulinotropic polypeptide may enhance fatty acid re-esterification in subcutaneous abdominal adipose tissue in lean humans

    Asmar, M., Simonsen, L., Madsbad, Sten, Stallknecht, Bente Merete, Holst, Jens Juul & Bülow, J., 1 Sep 2010, In: Diabetes. 59, 9, p. 2160-3 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Glucagon-like peptide-2, but not glucose-dependent insulinotropic polypeptide, stimulates glucagon release in patients with type 1 diabetes

    Christensen, M., Knop, Filip Krag, Vilsbøll, Tina, Aaboe, K., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 9 Aug 2010, In: Regulatory Peptides. 163, 1-3, p. 96-101 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Dipeptidyl peptidase expression during experimental colitis in mice

    Yazbeck, R., Sulda, M. L., Howarth, G. S., Bleich, A., Raber, K., von Hörsten, S., Holst, Jens Juul & Abbott, C. A., 1 Aug 2010, In: Inflammatory Bowel Diseases. 16, 8, p. 1340-1351 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Impact of exogenous hyperglucagonemia on postprandial concentrations of gastric inhibitory polypeptide and glucagon-like peptide-1 in humans

    Meier, J. J., Ritter, P. R., Jacob, A., Menge, B. A., Deacon, Carolyn F., Schmidt, W. E., Nauck, M. A. & Holst, Jens Juul, 1 Aug 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 8, p. 4061-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Sex steroids affect triglyceride handling, glucose-dependent insulinotropic polypeptide, and insulin sensitivity: a 1-week randomized clinical trial in healthy young men

    Lapauw, B., Ouwens, M., 't Hart, L. M., Wuyts, B., Holst, Jens Juul, T'Sjoen, G., Kaufman, J. & Ruige, J. B., 1 Aug 2010, In: Diabetes Care. 33, 8, p. 1831-3 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Reduced glucose tolerance and insulin resistance induced by steroid treatment, relative physical inactivity, and high-calorie diet impairs the incretin effect in healthy subjects

    Hansen, K. B., Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 1 Jul 2010, In: The Journal of clinical endocrinology and metabolism. 95, 7, p. 3309-17 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action

    Hare, K. J., Vilsbøll, Tina, Asmar, M., Deacon, Carolyn F., Knop, Filip Krag & Holst, Jens Juul, 1 Jul 2010, In: Diabetes. 59, 7, p. 1765-70 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Actions of prolonged ghrelin infusion on gastrointestinal transit and glucose homeostasis in humans

    Falkén, Y., Hellström, P. M., Sanger, G. J., Dewit, O., Dukes, G., Grybäck, P., Holst, Jens Juul & Näslund, E., 1 Jun 2010, In: Neurogastroenterology and Motility. 22, 6, p. e192-200

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Effect of growth in infancy on body composition, insulin resistance, and concentration of appetite hormones in adolescence

    Larnkjær, Anni, Schack-Nielsen, L., Mølgaard, Christian, Ingstrup, H. K., Holst, Jens Juul & Michaelsen, Kim F., 1 Jun 2010, In: American Journal of Clinical Nutrition. 91, 6, p. 1675-83 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?

    Asmar, M., Bache, M., Knop, Filip Krag, Madsbad, Sten & Holst, Jens Juul, 1 May 2010, In: The Journal of clinical endocrinology and metabolism. 95, 5, p. 2367-75 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The influence of nutrients, biliary-pancreatic secretions, and systemic trophic hormones on intestinal adaptation in a Roux-en-Y bypass model

    Taqi, E., Wallace, L. E., de Heuvel, E., Chelikani, P. K., Zheng, H., Berthoud, H., Holst, Jens Juul & Sigalet, D. L., 1 May 2010, In: European Journal of Pediatric Surgery. Supplement. 45, 5, p. 987-95 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Little enhancement of meal-induced glucagon-like peptide 1 secretion in Japanese: Comparison of type 2 diabetes patients and healthy controls

    Yabe, D., Kuroe, A., Lee, S., Watanabe, K., Hyo, T., Hishizawa, M., Kurose, T., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N. & Seino, Y., 22 Apr 2010, In: Journal of Diabetes Investigation. 1, 1-2, p. 56-9 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Automated detection of hypoglycemia-induced EEG changes recorded by subcutaneous electrodes in subjects with type 1 diabetes--the brain as a biosensor

    Juhl, C. B., Højlund, K., Elsborg, R., Poulsen, M. K., Selmar, P. E., Holst, Jens Juul, Christiansen, C. & Beck-Nielsen, H., 1 Apr 2010, In: Diabetes Research and Clinical Practice. 88, 1, p. 22-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Inappropriate glucagon response after oral compared with isoglycemic intravenous glucose administration in patients with type 1 diabetes

    Hare, K. J., Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 1 Apr 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 4, p. E832-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    The effects of exercise-induced weight loss on appetite-related peptides and motivation to eat

    Martins, C., Kulseng, B., King, N. A., Holst, Jens Juul & Blundell, J. E., 1 Apr 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 4, p. 1609-16 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus

    Aaboe, K., Knop, Filip Krag, Vilsbøll, T., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, S. & Krarup, T. M., 1 Apr 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-33 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Reversible hyperinsulinemic hypoglycemia after gastric bypass: a consequence of altered nutrient delivery

    McLaughlin, T., Peck, M., Holst, Jens Juul & Deacon, Carolyn F., Apr 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 4, p. 1851-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Similar incretin secretion in obese and non-obese Japanese subjects with type 2 diabetes

    Kozawa, J., Okita, K., Imagawa, A., Iwahashi, H., Holst, Jens Juul, Yamagata, K. & Shimomura, I., 12 Mar 2010, In: Biochemical and Biophysical Research Communications. 393, 3, p. 410-3 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Cardiovascular and metabolic effects of 48-h glucagon-like peptide-1 infusion in compensated chronic patients with heart failure

    Halbirk, M., Nørrelund, H., Møller, N., Holst, Jens Juul, Schmitz, O., Nielsen, B. R. R., Nielsen-Kudsk, J. E., Nielsen, S. S., Nielsen, T. T., Eiskjaer, H., Bøtker, H. E. & Wiggers, H., 1 Mar 2010, In: American Journal of Physiology: Heart and Circulatory Physiology. 298, 3, p. H1096-H1102

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide: new advances

    Asmar, M. & Holst, Jens Juul, 1 Feb 2010, In: Current Opinion in Endocrinology, Diabetes and Obesity. 17, 1, p. 57-62 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The effect of glucagon-like peptide-2 on arterial blood flow and cardiac parameters

    Bremholm, L., Hornum, Mads, Andersen, U. B. & Holst, Jens Juul, 8 Jan 2010, In: Regulatory Peptides. 159, 1-3, p. 67-71 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Effects of fat supplementation on postprandial GIP, GLP-1, ghrelin and IGFBP-1 levels: a pilot study on adolescents with type 1 diabetes

    Lodefalk, M., Carlsson-Skwirut, C., Holst, Jens Juul, Aman, J. & Bang, P., 1 Jan 2010, In: Hormone research in pædiatrics. 73, 5, p. 355-362 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Glucagon and glucagon-like peptides 1 and 2

    Holst, Jens Juul, 1 Jan 2010, In: Results and Problems in Cell Differentiation. 50, p. 121-35 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    The effect of glucagon-like Peptide-2 receptor agonists on colonic anastomotic wound healing

    Redstone, H. A., Buie, W. D., Hart, D. A., Wallace, L., Hornby, P. J., Sague, S., Holst, Jens Juul & Sigalet, D. L., 1 Jan 2010, In: Gastroenterology Research and Practice. 2010, p. Article ID 672453 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes

    Deacon, Carolyn F. & Holst, Jens Juul, Jan 2010, In: Expert Opinion on Investigational Drugs. 19, 1, p. 133-40 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Little enhancement of meal-induced GLP-1 secretion in Japanese: Comparison of type 2 diabetes and healthy controls

    Yabe, D., Kuroe, A., Lee, S., Watanabe, K., Hyo, T., Hishizawa, M., Kurose, T., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N. & Seino, Y., Jan 2010, In: Journal of Diabetes Investigation. 1, 1/2, p. 56-59

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Acute effects of casein on postprandial lipemia and incretin responses in type 2 diabetic subjects

    Brader, L. J., Holm, L., Mortensen, L., Thomsen, C., Astrup, A., Holst, Jens Juul, Vrese, M. D., Schrezenmeir, J. & Hermansen, K., 2010, In: Nutrition, Metabolism & Cardiovascular Diseases. 20, 2, p. 101-109 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Effect of glucagon-like peptide-1 on alpha- and beta-cell function in C-peptide-negative type 1 diabetic patients

    Kielgast, U., Asmar, M., Madsbad, Sten & Holst, Jens Juul, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 5, p. 2492-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Increased Postprandial Response of Glucagon-Like Peptide-2 in Patients with Chronic Pancreatitis and Pancreatic Exocrine Insufficiency

    Hornum, Mads, Pedersen, J. F., Larsen, S., Olsen, O., Holst, Jens Juul & Knop, Filip Krag, 2010, In: Pancreatology. 10, 2-3, p. 201-207 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Insulinets vej ind i det danske samfund

    Larsen, Erik Hviid & Holst, Jens Juul, 2010, Det fremmede som historisk drivkraft. Danmark efter 1742: Et festskrift til Hendes Majestæt Dronning Margrethe II ved 70-års-fødselsdagen den 16. april 2010. Nielsen, M. A. (ed.). København: Det Kongelige Danske Videnskabernes Selskab, p. 85-94

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  42. Published

    Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes

    Deacon, Carolyn F. & Holst, Jens Juul, 2010, In: Expert Opinion on Investigational Drugs. 19, 1, p. 133-140 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  43. Published

    On the role of glucose-dependent insulintropic polypeptide in postprandial metabolism in humans

    Asmar, M., Tangaa, W., Madsbad, Sten, Hare, K., Astrup, A., Flint, A., Bülow, J. & Holst, Jens Juul, 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 3, p. E614-21 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes

    Asmar, M., Højberg, P. V., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-80 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Pancreatic ß-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes

    Asmar, M., Højberg, P., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-180 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Postprandial diabetic glucose tolerance is normalized by gastric bypass feeding as opposed to gastric feeding and is associated with exaggerated GLP-1 secretion: a case report

    Dirksen, C., Hansen, D. L., Madsbad, Sten, Hvolris, L. E., Naver, L. S., Holst, Jens Juul & Worm, Dorte, 2010, In: Diabetes Care. 33, 2, p. 375-377

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Secretion and dipeptidyl peptidase-4-mediated metabolism of incretin hormones after a mixed meal or glucose ingestion in obese compared to lean, nondiabetic men

    Carr, R. D., Larsen, M. O., Jelic, K., Lindgren, O., Vikman, J., Holst, Jens Juul, Deacon, Carolyn F. & Ahrén, B., 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 2, p. 872-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    The T-allele of TCF7L2 rs7903146 associates with a reduced compensation of insulin secretion for insulin resistance induced by 9 days of bed rest

    Alibegovic, A. C., Sonne, M. P., Højbjerre, L., Hansen, T., Pedersen, Oluf Borbye, van Hall, Gerrit, Holst, Jens Juul, Stallknecht, Bente Merete, Dela, Flemming & Vaag, A., 2010, In: Diabetes. 59, 4, p. 836-43 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The effect of DPP-4 inhibition with sitagliptin on incretin secretion and on fasting and postprandial glucose turnover in subjects with impaired fasting glucose

    Bock, G., Man, C. D., Micheletto, F., Basu, R., Rn, P. D. G., Laugen, J., Deacon, Carolyn F., Holst, Jens Juul, Toffolo, G., Cobelli, C., Rizza, R. A. & Vella, A., 2010, In: Clinical Endocrinology. 73, p. 189-196

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose- and non-glucose-induced insulin secretion in patients with type 2 diabetes mellitus

    Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-333 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 4207