Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas

    de Heer, J., Rasmussen, C., Coy, D. H. & Holst, Jens Juul, Dec 2008, In: Diabetologia. 51, 12, p. 2263-70 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The alpha cell expresses glucagon-like peptide-2 receptors and glucagon-like peptide-2 stimulates glucagon secretion from the rat pancreas

    de Heer, J., Pedersen, J., Ørskov, Cathrine & Holst, Jens Juul, Oct 2007, In: Diabetologia. 50, 10, p. 2135-42 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Sulfonylurea compounds uncouple the glucose dependence of the insulinotropic effect of glucagon-like peptide 1.

    de Heer, J. & Holst, Jens Juul, 2007, In: Diabetes. 56, 2, p. 438-43 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Exogenous GLP-2 has only marginal effects on weaning-induced intestinal adaption in piglets

    le Huërou-Luron, I., Petersen, Y. M., Hartmann, B., Holst, Jens Juul & Sangild, Per Torp, 2003, Ikke angivet. R.O. Ball (ed.). 2 ed. University of Alberta Press, p. 164-166 3 p.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

  5. Published

    Butyrate and hexanoate-enriched triglycerides increase postprandrial systemic butyrate and hexanoate in men with overweight/obesity: A double-blind placebo-controlled randomized crossover trial

    van Deuren, T., Smolders, L., Hartog, A., Bouwman, F. G., Holst, Jens Juul, Venema, K., Blaak, E. E. & Canfora, E. E., 2023, In: Frontiers in Nutrition. 9, 19 p., 1066950.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Cerebral effects of glucagon-like peptide-1 receptor blockade before and after Roux-en-Y gastric bypass surgery in obese women: A proof-of-concept resting-state functional MRI study

    van Duinkerken, E., Bernardes, G., van Bloemendaal, L., Veltman, D. J., Barkhof, F., Mograbi, D. C., Gerdes, V. E. A., Deacon, Carolyn F., Holst, Jens Juul, Drent, M. L., Diamant, M., ten Kulve, J. & Ijzerman, R. G., 2021, In: Diabetes, Obesity and Metabolism. 23, 2, p. 415-424 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The interleukin-1 receptor antagonist anakinra improves first-phase insulin secretion and insulinogenic index in subjects with impaired glucose tolerance

    van Poppel, P. C. M., van Asseldonk, E. J. P., Holst, Jens Juul, Vilsbøll, Tina, Netea, M. G. & Tack, C. J., Dec 2014, In: Diabetes, Obesity and Metabolism. 16, 12, p. 1269-73 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  8. Published

    Islet-cell dysfunction induced by glucocorticoid treatment: potential role for altered sympathovagal balance?

    van Raalte, D. H., Kwa, K. A. A., van Genugten, R. E., Tushuizen, M. E., Holst, Jens Juul, Deacon, Carolyn F., Karemaker, J. M., Heine, R. J., Mari, A. & Diamant, M., 2013, In: Metabolism. 62, 4, p. 568-577 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Distal, not proximal, colonic acetate infusions promote fat oxidation and improve metabolic markers in overweight/obese men

    van der Beek, C. M., Canfora, E. E., Lenaerts, K., Troost, F. J., Damink, S. W. M. O., Holst, Jens Juul, Masclee, A. A. M., Dejong, C. H. C. & Blaak, E. E., 11 Oct 2016, In: Clinical Science. 130, 22, p. 2073-2082 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The prebiotic inulin improves substrate metabolism and promotes short-chain fatty acid production in overweight to obese men

    van der Beek, C. M., Canfora, E. E., Kip, A. M., Gorissen, S. H. M., Damink, S. W. M. O., van Eijk, H. M., Holst, Jens Juul, Blaak, E. E., Dejong, C. H. C. & Lenaerts, K., Oct 2018, In: Metabolism. 87, p. 25-35

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Chenodeoxycholic acid reduces intestinal permeability in newly weaned piglets

    van der Meer, Y., Gerrits, W. J. J., van den Bosch, M., Holst, Jens Juul, Moreto, M., Buurman, W. A., Kulik, W. & van Kempen, T. A. T. G., Dec 2012, In: Journal of Animal Science. 90 Suppl 4, p. 302-4 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    GLP-1 Val8: A Biased GLP-1R Agonist with Altered Binding Kinetics and Impaired Release of Pancreatic Hormones in Rats

    van der Velden, W. J. C., Smit, F. X., Christiansen, Charlotte Bayer, Møller, T. C., Hjortø, Gertrud Malene, Larsen, Olav, Schiellerup, S. P., Bräuner, Hans, Holst, Jens Juul, Hartmann, Bolette, Frimurer, Thomas Michael & Rosenkilde, Mette, 2021, In: ACS Pharmacology & Translational Science. 4, 1, p. 296-313 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Molecular and in vivo phenotyping of missense variants of the human glucagon receptor

    van der Velden, W. J. C., Lindquist, Peter, Madsen, Jakob Sture, Stassen, R. H. M. J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, M. M., 2022, In: Journal of Biological Chemistry. 298, 2, 101413.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Endurance training improves GLP-1 sensitivity and glucose tolerance in overweight women

    Åkerström, T., Stolpe, Malene Norup, Widmer, R., Dejgaard, T. F., Højberg, J. M., Møller, Kirsten, Hansen, J. S., Trinh, B., Holst, Jens Juul, Thomsen, C., Pedersen, Bente Klarlund & Ellingsgaard, H., 2022, In: Journal of the Endocrine Society. 6, 9, p. 1-8 8 p., bvac111.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Counterregulatory responses to postprandial hypoglycemia after Roux-en-Y gastric bypass

    Øhrstrøm, C. C., Hansen, D. L., Kielgast, U. L., Bergmann, M. L., Veedfald, Simon, Holst, Jens Juul & Worm, Dorte, 2021, In: Surgery for Obesity and Related Diseases. 17, 1, p. 55-63 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Evidence for Relationship Between Early Dumping and Postprandial Hypoglycemia After Roux-en-Y Gastric Bypass

    Øhrstrøm, C. C., Worm, Dorte, Kielgast, U. L., Holst, Jens Juul & Hansen, D. L., 2020, In: Obesity Surgery. 30, 3, p. 1038-1045

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The effect of glucose on the plasma concentration of somatostatin during caloric deficiency in man

    Øktedalen, O., Opstad, P. K. & Holst, Jens Juul, 1993, In: Scandinavian Journal of Gastroenterology. 28, p. 652-656

    Research output: Contribution to journal › Journal article › Research

  18. Published

    The role of somatostatin in GLP-1-induced inhibition of glucagon secretion in mice

    Ørgaard, A. & Holst, Jens Juul, Sep 2017, In: Diabetologia. 60, 9, p. 1731-1739 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Short-chain fatty acids and regulation of pancreatic endocrine secretion in mice

    Ørgaard, A., Jepsen, Sara Lind & Holst, Jens Juul, 2019, In: Islets. 11, 5, p. 103-111

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Neurogenic nitric oxide and exocrine secretion in the gastrointestinal tract

    Ørskov, Cathrine & Holst, Jens Juul, 2000, Nitric Oxide and the Peripheral Nervous System. London, UK: Portland Press Ltd., p. 131

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  21. Published

    Secretion and effects of glucagon-like peptide-1 (GLP-1) in healthy volunteers and NIDDM subjects.

    Ørskov, C. & Holst, Jens Juul, 1995, Diabetes 1994. Elsevier Sci. Intl. Congress Series 1100, p. 513-516

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  22. Published

    GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptors.

    Ørskov, Cathrine, Hartmann, B., Poulsen, Steen Seier, Thulesen, J., Hare, K. J. & Holst, Jens Juul, 2005, In: Regulatory Peptides. 124, 1-3, p. 105-12 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide-1 in humans

    Ørskov, Cathrine, Rabenhøj, L., Wettergren, A., Kofod, H. & Holst, Jens Juul, 1994, In: Diabetes. 43, p. 535-539

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    All products of proglucagon are elevated in plasma from ureamic patients

    Ørskov, Cathrine, Andreasen, J. & Holst, Jens Juul, 1992, In: Journal of Clinical Endocrinology and Metabolism. 79, p. 379-383

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Production and secretion of amidated and glycine-extended glucagon-like peptide-1 (GLP) in man

    Ørskov, C., Rabenhøj, L., Kofod, H., Wettergren, A. & Holst, Jens Juul, 1994, In: Diabetes. 43, p. 535-39

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Proglucagon products in plasma of uraemic patients and normals in the fasting state

    Ørskov, C., Andreasen, J. & Holst, Jens Juul, 1992, In: J. Clin. Endocrinol. Metab.. 74, p. 379-384

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting-state and after oral glucose and intravenous arginine

    Ørskov, C., Jeppesen, J., Madsbad, J. & Holst, Jens Juul, 1991, In: J. Clin. Invest.. 87, p. 415-423

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Biological effects and metabolic rates of GLP-1 7-36 amide and GLP-1 7-37 in healthy volunteers are indistinguishable

    Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, 1993, In: Diabetes. 42, p. 658-661

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young

    Østoft, S. H., Bagger, J. I., Hansen, Torben, Hartmann, Bolette, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 1 Aug 2015, In: European Journal of Endocrinology. 173, 2, p. 205-215 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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