Christian Aalkjær

Christian Aalkjær

Emeritus

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    1. Published

      Dynein coordinates β2-adrenoceptor-mediated relaxation in normotensive and hypertensive rat mesenteric arteries

      van der Horst, Jennifer, Rognant, Salomé, Hellsten, Ylva, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2022, In: Hypertension. 79, 10, p. 2214-2227 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Dynein regulates Kv7.4 channel trafficking from the cell membrane

      van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael J., Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome

      Thorsen, K., Dam, V. S., Kjaer-Sorensen, K., Pedersen, L. N., Skeberdis, V. A., Jurevicius, J., Treinys, R., Petersen, I. M. B. S., Nielsen, Morten Schak, Oxvig, C., Morth, J. P., Matchkov, V. V., Aalkjær, Christian, Bundgård, Henning & Jensen, H. K., 22 Nov 2017, In: Nature Communications. 8, 10 p., 1696.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Human lymphatic vessel contractile activity is inhibited in vitro but not in vivo by the calcium channel blocker nifedipine

      Telinius, N., Mohanakumar, S., Majgaard, J., Kim, S., Pilegaard, H., Pahle, E., Nielsen, J., de Leval, M., Aalkjær, Christian, Hjortdal, Vibeke Elisabeth & Boedtkjer, D. B., 1 Nov 2014, In: The Journal of Physiology. 592, 21, p. 4697-714 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      The human thoracic duct is functionally innervated by adrenergic nerves

      Telinius, N., Baandrup, U., Rumessen, J., Pilegaard, H., Hjortdal, Vibeke Elisabeth, Aalkjær, Christian & Boedtkjer, D. B., 15 Jan 2014, In: A J P: Heart and Circulatory Physiology (Online). 306, 2, p. H206-13

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Spontaneous and Evoked Contractility of Human Intestinal Lymphatic Vessels

      Telinius, N., Majgaard, J., Mohanakumar, S., Pahle, E., Nielsen, J., Hjortdal, Vibeke Elisabeth, Aalkjær, Christian & Boedtkjer, D. B., Mar 2017, In: Lymphatic Research and Biology. 15, 1, p. 17-22 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      The contribution of K(+) channels to human thoracic duct contractility

      Telinius, N., Kim, S., Pilegaard, H., Pahle, E., Nielsen, J., Hjortdal, Vibeke Elisabeth, Aalkjær, Christian & Boedtkjer, D. B., 1 Jul 2014, In: A J P: Heart and Circulatory Physiology (Online). 307, 1, p. H33-43

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Voltage-gated sodium channels contribute to action potentials and spontaneous contractility in isolated human lymphatic vessels

      Telinius, N., Majgaard, J., Kim, S., Katballe, N., Pahle, E., Nielsen, J., Hjortdal, Vibeke Elisabeth, Aalkjær, Christian & Boedtkjer, D. B., 15 Jul 2015, In: The Journal of Physiology. 593, 14, p. 3109-22 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Human thoracic duct in vitro: diameter-tension properties, spontaneous and evoked contractile activity

      Telinius, N., Drewsen, N., Pilegaard, H., Kold-Petersen, H., de Leval, M., Aalkjær, Christian, Hjortdal, Vibeke Elisabeth & Boedtkjer, D. B., Sep 2010, In: A J P: Heart and Circulatory Physiology (Online). 299, 3, p. H811-8

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Migraine-Associated Mutation in the Na,K-ATPase Leads to Disturbances in Cardiac Metabolism and Reduced Cardiac Function

      Staehr, C., Rohde, P. D., Krarup, N. T., Ringgaard, S., Laustsen, C., Johnsen, J., Nielsen, R., Beck, H. C., Morth, J. P., Lykke-Hartmann, K., Jespersen, N. R., Abramochkin, D., Nyegaard, M., Botker, H. E., Aalkjær, Christian & Matchkov, V., 2022, In: Journal of the American Heart Association. 11, 7, 47 p., 021814.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Abnormal neurovascular coupling as a cause of excess cerebral vasodilaion in familial migarine

      Staehr, C., Rajanathan, R., Postnov, D. D., Hangaard, L., Bouzinova, E., Lykke-Hartmann, K., Bach, F. W., Sandow, S. L., Aalkjær, Christian & Matchkov, V. V., 2020, In: Cardiovascular Research. 116, 12, p. 2009-2020 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Rat mesenteric small artery neurogenic dilatation is predominantly mediated by beta(1)-adrenoceptors in vivo

      Sondergaard, A. M., Overgaard, C. B., Mazur, A., Postnov, D. D., Matchkov, V. V. & Aalkjær, Christian, 2019, In: The Journal of Physiology. 597, 7, p. 1819-1831

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      The thick left ventricular wall of the giraffe heart normalises wall tension, but limits stroke volume and cardiac output

      Smerup, M., Damkjær, M., Brøndum, E. T., Baandrup, U. T., Kristiansen, S. B., Nygaard, H., Funder, J. A., Aalkjær, Christian, Sauer, C., Buchanan, R., Bertelsen, Mads Frost, Østergaard, K. H., Grøndahl, C., Candy, G., Hasenkam, J. M., Secher, Niels H., Bie, P. & Wang, T., 2016, In: The Journal of Experimental Biology. 219, 3, p. 457-463 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Perivascular Adipose Tissue Contributes to the Modulation of Vascular Tone in vivo

      Saxton, S. N., Withers, S. B., Nyvad, J., Mazur, A., Matchkov, V., Heagerty, A. M. & Aalkjær, Christian, 2019, In: Journal of Vascular Research. 56, 6, p. 320-332

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      GLP-1 and its Analogue Liraglutide Affects Human Endothelial Cell Signaling by Reducing VEGF-A Induced Ca2+ Signaling and Activating Protein Kinases

      Rotbøl, C. E., Hansen, A., Tritsaris, Katerina, Xu, J., Aalkjær, Christian & Dissing, Steen, Apr 2015, In: F A S E B Journal. 29, 1 supplement, 1 p., 642.7.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    16. Published

      GLP-1 inhibits VEGFA-mediated signaling in isolated human endothelial cells and VEGFA-induced dilation of rat mesenteric arteries

      Rotbøl, C. E., Khammy, M. M., Dalsgaard, T., Mazur, A., Tritsaris, Katerina, Hansen, A. J., Aalkjær, Christian & Dissing, Steen, 1 Nov 2016, In: American Journal of Physiology: Heart and Circulatory Physiology. 311, 5, p. H1214-H1224

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Acute, pro-contractile effects of prorenin on rat mesenteric arteries

      Rognant, Salomé, Baldwin, S. N., Pritchard, H. A. T., Greenstein, A., Callø, Kirstine, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2023, In: FASEB Journal. 37, 12, 18 p., e23282.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      The microtubule network enables Src kinase interaction with the Na,K-ATPase to generate Ca2+ flashes in smooth muscle cells

      Rognant, Salomé, Kravtsova, V. V., Bouzinova, E. V., Melnikova, E. V., Krivoi, I. I., Pierre, S. V., Aalkjær, Christian, Jepps, Thomas Andrew Qvistgaard & Matchkov, V. V., 2022, In: Frontiers in Physiology. 13, 14 p., 1007340.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Protection against high intravascular pressure in giraffe legs

      Petersen, K. K., Hørlyck, A., Østergaard, K. H., Andresen, J., Brøgger, T. H., Jensen, N. S., Telinius, N., Laher, I., Bertelsen, Mads Frost, Grøndahl, C., Smerup, M. H., Secher, Niels H., Brøndum, E. T., Hasenkam, J. M., Wang, T., Baandrup, U. & Aalkjær, Christian, 2013, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 305, 9, p. R1021-R1030 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Intravital investigation of rat mesenteric small artery tone and blood flow

      Nyvad, J., Mazur, A., Postnov, D. D., Straarup, M. S., Soendergaard, A. M., Staehr, C., Brøndum, E., Aalkjær, Christian & Matchkov, V. V., 2017, In: Journal of Physiology. 595, 15, p. 5037-5053 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Increased NBCn1 expression, Na+/HCO- 3 co-transport and intracellular pH in human vascular smooth muscle cells with a risk allele for hypertension

      Ng, F. L., Boedtkjer, E., Witkowska, K., Ren, M., Zhang, R., Tucker, A., Aalkjær, Christian, Caulfield, M. J. & Ye, S., 2017, In: Human Molecular Genetics. 26, 5, p. 989-1002 14 p., ddx015.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Microtubule Regulation of Kv7 Channels Orchestrates cAMP-Mediated Vasorelaxations in Rat Arterial Smooth Muscle

      Lindman, J., Khammy, M. M., Lundegaard, Pia Rengtved, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: Hypertension. 71, 2, p. 336-345 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: contributions to pHi regulation and chemotherapy resistance

      Lauritzen, G., Jensen, M. B. F., Bødtkjer, E., Dybboe, R., Aalkjær, Christian, Nylandsted, J. & Pedersen, Stine Helene Falsig, 10 Sep 2010, In: Experimental Cell Research. 316, 15, p. 2538-53 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Phosphodiesterase 1a inhibition elicits cGMP-dependent relaxation of rat mesenteric arteries

      Khammy, M. M., Dalsgaard, T., Larsen, P. H., Christoffersen, C. T., Clausen, D., Rasmussen, L. K., Folkersen, L., Grunnet, Morten, Kehler, J., Aalkjær, Christian & Nielsen, J., Nov 2017, In: British Journal of Pharmacology. 174, 22, p. 4186-4198 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances K7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries

      Khammy, M. M., Kim, S., Bentzen, Bo Hjorth, Lee, S., Choi, I., Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: British Journal of Pharmacology. 175, 3, p. 501-516 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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