Cathrine Ørskov

Cathrine Ørskov

Head of Department


  1. Published

    A processing enzyme cleaving avian progastrin at post-Phe bonds

    Jensen, H., Ørskov, Cathrine, Rehfeld, Jens Frederik & Johnsen, A. H., 5 May 2001, In: B B A - Reviews on Cancer. 1547, 1, p. 64-71 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations

    Nauck, M. A., Bartels, Emil Daniel, Ørskov, Cathrine, Ebert, R. & Creutzfeldt, W., Apr 1993, In: Endocrinology. 76, 4, p. 912-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue

    Lundh, M., Petersen, P. S., Isidor, Marie Sophie, Kazoka-Sørensen, D. N., Plucinska, Kaja, Shamsi, F., Ørskov, Cathrine, Tozzi, M., Brown, E. L., Andersen, E., Ma, Tao, Müller, U. A., Barrès, Romain, Kristiansen, V. B., Gerhart-Hines, Zach, Tseng, Y. & Emanuelli, Brice, 2019, In: EMBO Reports. 20, 8, e48216.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    All products of proglucagon are elevated in plasma from ureamic patients

    Ørskov, Cathrine, Andreasen, J. & Holst, Jens Juul, 1992, In: Journal of Clinical Endocrinology and Metabolism. 79, p. 379-383

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Amino acids differ in their capacity to stimulate GLP-1 release from the perfused rat small intestine and stimulate secretion by different sensing mechanisms

    Modvig, Ida Marie, Kuhre, Rune Ehrenreich, Jepsen, Sara Lind, Xu, S., Engelstoft, M. S., Egerod, Kristoffer Lihme, Schwartz, Thue W., Ørskov, Cathrine, Rosenkilde, Mette & Holst, Jens Juul, 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 320, p. E874-E885 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Antidiabetogenic Effect of glucagon-like peptide-1 (7-36) amide in normal subjects and patients with diabetes mellitus

    Gutniak, M., Ørskov, Cathrine, Holst, Jens Juul, Ahrén, B. & Efendic, S., 1992, In: New England Journal of Medicine. 326, p. 1316-1322

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Basal and nutrient stimulated pancreatic and gastrointestinal hormone concentrations in type-1 diabetes patients after succesful combined pancreas and kidney transplantation

    Nauck, M., Büsing, M., Ørskov, Cathrine, Siegel, E. G., Talartschik, J., Baartz, A., Baartz, T., Hopt, U. T., Ebert, R., Becker, H. & Creutzfeldt, W., 1992, In: Clinical Investigator. 70, p. 40-48

    Research output: Contribution to journalJournal articleResearch

  8. Published

    Biological effects and metabolic rates of GLP-1 7-36 amide and GLP-1 7-37 in healthy volunteers are indistinguishable

    Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, 1993, In: Diabetes. 42, p. 658-661

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Biological effects and metabolic rates of glucagonlike peptide-1 7-36 amide and glucagonlike peptide-1 7-37 in healthy subjects are indistinguishable

    Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, May 1993, In: Diabetes. 42, 5, p. 658-61 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Carboxypeptidase-B-like processing of the C-terminus of glucagon-like peptide-2 in pig and human small intestine

    Ørskov, Cathrine, Buhl, T., Rabenhøj, L., Kofod, H. & Holst, Jens Juul, 24 Apr 1989, In: F E B S Letters. 247, 2, p. 193-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes

    Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, A. C., Jansen-Olesen, I., Chiarelli, F., Holst, J. J., Hougaard, P. P., Porksen, S., Holl, R., Beaufort, C. D., Gammeltoft, S., Rorsman, P., Mortensen, H. B., Hansen, L., Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, C., Jansen-Olesen, I. & 11 others, Chiarelli, F., Holst, J. J., Hougaard, P., Pörksen, S., Holl, R., de Beaufort, C., Gammeltoft, S., Rorsman, P., Mortensen, H. B., Hansen, L. & Hvidøre Study Group, H. S. G., 2007, In: European Journal of Endocrinology. 156, 6, p. 663-71 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes

    Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, Cathrine, Jansen-Olesen, I., Chiarelli, F., Holst, Jens Juul, Hougaard, P., Pörksen, S., Holl, R., de Beaufort, C., Gammeltoft, S., Rorsman, P., Mortensen, H. B. & Hansen, L., Jun 2007, In: European Journal of Endocrinology. Supplement. 156, 6, p. 663-71 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Colocalization of GLP-1 and GIP in human and porcine intestine

    Mortensen, K., Petersen, L. L. & Ørskov, Cathrine, 2000, In: Annals of the New York Academy of Sciences. 921, p. 469-72 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Complete sequences of glucagon-like peptide-1 from human and pig small intestine

    Ørskov, Cathrine, Bersani, M., Johnsen, A. H., Højrup, P. & Holst, Jens Juul, 5 Aug 1989, In: The Journal of Biological Chemistry. 264, 22, p. 12826-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Constitutive activity of glucagon receptor mutants

    Hjorth, S. A., Ørskov, Cathrine & Schwartz, Thue W., 1998, In: Molecular Endocrinology. 12, no. 1, p. 78-86

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagon-like peptide-2 in rats and mice

    Hartmann, Bolette, Thulesen, J., Kissow, Hannelouise, Thulesen, S., Ørskov, Cathrine, Ropke, C., Poulsen, Steen Seier & Holst, Jens Juul, 2000, In: Endocrinology. 141, 11, p. 4013-20 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis

    Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørskov, Cathrine, Kissow, Hannelouise, Poulsen, Steen Seier, Vilstrup, H., Prehn, C., Adamski, J., Jepsen, Sara Lind, Hartmann, Bolette, Dal, Jenna Elizabeth Hunt, Charron, M. J., Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 1, p. E93-E103

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem

    Larsen, P. J., Tang-Christensen, M., Holst, Jens Juul & Ørskov, Cathrine, 1997, In: Neuroscience. Vol. 77, No. 1, p. 257-270

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Effect of glucagon-like peptide-1 (proglucagon 78 - 107 amide) on hepatic glucose production in healthy man

    Hvidberg, A., Nielsen, M. T., Hilsted, J., Ørskov, Cathrine & Holst, Jens Juul, 1994, In: Metabolism. 43, p. 104-108

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Effect of glucagon-like peptide-1 (proglucagon 78-107amide) on hepatic glucose production in healthy man

    Hvidberg, A., Nielsen, M. T., Hilsted, J., Ørskov, Cathrine & Holst, Jens Juul, Jan 1994, In: Metabolism. 43, 1, p. 104-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Effect of truncated glucagon-like peptide-1 [proglucagon-(78-107) amide] on endocrine secretion from pig pancreas, antrum, and nonantral stomach

    Ørskov, Cathrine, Holst, Jens Juul & Nielsen, O. V., Oct 1988, In: Molecular Endocrinology. 123, 4, p. 2009-13 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM

    Nauck, M. A., Wollschläger, D., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Willms, B., Dec 1996, In: Diabetologia. 39, 12, p. 1546-53 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published
  24. Published

    Expression Profile of the GLP-1 Receptor in the Gastrointestinal Tract and Pancreas in Adult Female Mice

    Grunddal, Kaare Villum, Jensen, E. P., Ørskov, Cathrine, Andersen, Daniel Bjørklund, Windeløv, Johanne Agerlin, Poulsen, Steen Seier, Rosenkilde, M. M., Knudsen, L. B., Pyke, C. & Holst, Jens Juul, 2022, In: Endocrinology. 163, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Fasting decreases plasma FGF21 in obese subjects and the expression of FGF21 receptors in adipose tissue in both lean and obese subjects

    Nygaard, E. B., Ørskov, Cathrine, Almdal, Thomas Peter, drb459, drb459 & Andersen, B., 2018, In: Journal of Endocrinology. 239, 1, p. 73-80

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans

    Schjoldager, B. T., Mortensen, P. E., Christiansen, J., Ørskov, Cathrine & Holst, Jens Juul, May 1989, In: Digestive Diseases and Sciences. 34, 5, p. 703-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine

    Mortensen, K., Christensen, L. L., Holst, Jens Juul & Ørskov, Cathrine, 2003, In: Regulatory Peptides. 114, 2-3, p. 189-96 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    GLP-1 does not not acutely affect insulin sensitivity in healthy man

    Orskov, L., Holst, Jens Juul, Møller, J., Ørskov, Cathrine, Møller, N., Alberti, K. G. & Schmitz, O., Oct 1996, In: Diabetologia. 39, 10, p. 1227-32 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. GLP-1 receptor localization in monkey and human tissue: novel distribution revealed with extensively validated monoclonal antibody

    Pyke, C., Heller, R. S., Kirk, R. K., Ørskov, Cathrine, Reedtz-Runge, S., Kaastrup, P., Hvelplund, A., Bardram, L., Calatayud, D. & Knudsen, L. B., Apr 2014, In: Endocrinology. 155, 4, p. 1280-90 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    GLP-1-induced renal vasodilation in rodents depends exclusively on the known GLP-1 receptor and is lost in pre-hypertensive rats

    Jensen, E. P., Møller, S., Hviid, A. V. R., Veedfald, Simon, Holst, Jens Juul, Pedersen, Jens, Ørskov, Cathrine & Sorensen, Charlotte Mehlin, 2020, In: American Journal of Physiology: Renal Physiology. 318, 6, p. F1409-F1417

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptors.

    Ørskov, Cathrine, Hartmann, B., Poulsen, Steen Seier, Thulesen, J., Hare, K. J. & Holst, Jens Juul, 2005, In: Regulatory Peptides. 124, 1-3, p. 105-12 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    GRP-producing nerves control antral somatostatin and gastrin secretion in pigs

    Holst, Jens Juul, Ørskov, Cathrine & Poulsen, Steen Seier, Dec 1987, In: American Journal of Physiology (Consolidated). 253, 6 Pt 1, p. G767-74

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients

    Willms, B., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Nauck, M. A., Jan 1996, In: Endocrinology. 81, 1, p. 327-32 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis

    Winther-Sørensen, M., Galsgaard, K. D., Santos, A., Trammell, S. A. J., Sulek, K., Kuhre, R. E., Pedersen, J., Andersen, D. B., Hassing, A. S., Dall, M., Treebak, J. T., Gillum, M. P., Torekov, S. S., Windeløv, J. A., Hunt, J. E., Kjeldsen, S. A. S., Jepsen, S. L., Vasilopoulou, C. G., Knop, F. K., Ørskov, C. & 7 others, Werge, M. P., Bisgaard, Hanne Cathrine, Eriksen, P. L., Vilstrup, H., Gluud, Lise Lotte, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Molecular Metabolism. 42, 18 p., 101080.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Glucagon and other proglucagon-derived peptides

    Holst, Jens Juul & Ørskov, Cathrine, 1994, Gut Peptides: Biochemistry and Physiology. New York: Raven Press, p. 305-340

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  36. Published
  37. Published

    Glucagon receptor signaling is not required for N-carbamoyl glutamate- And L-citrulline-induced ureagenesis in mice

    Galsgaard, Katrine Douglas, Pedersen, Jens, Kjeldsen, Sasha Alexandra Sampson, Winther-Sørensen, Marie, Stojanovska, E., Vilstrup, H., Ørskov, Cathrine, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 5, p. G912-G927

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Glucagon-like peptide 1 (7-36 amide) secretion in response to luminal sucrose from the upper and lower gut. A study using a-glucosidase inhibition (acarbose)

    Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 892-896

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans

    Nauck, M. A., Niedereichholz, U., Ettler, R., Holst, Jens Juul, Ørskov, Cathrine, Ritzel, R. & Schmiegel, W. H., Nov 1997, In: American Journal of Physiology (Consolidated). 273, 5 Pt 1, p. E981-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Glucagon-like peptide 2 (GLP-2) accelerates the growth of colonic neoplasms in mice

    Thulesen, J., Hartmann, Bolette, Hare, K. J., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Aug 2004, In: Gut. 53, 8, p. 1145-1150 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I

    Ørskov, Cathrine, Poulsen, Steen Seier, Møller, Morten & Holst, Jens Juul, Jun 1996, In: Diabetes. 45, 6, p. 832-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Glucagon-like peptide-1 (GLP-1) 7-36 amide and peptide YY from L-cell in the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man

    Wettergren, A., Petersen, H., Ørskov, Cathrine, Christiansen, J., Sheikh, S. & Holst, Jens Juul, 1994, In: Scandinavian Journal of Gastroenterology. 29, p. 501-505

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Glucagon-like peptide-1 7-36 amide and peptide YY from the L-cell of the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man

    Wettergren, A., Petersen, H., Ørskov, Cathrine, Christiansen, J., Sheikh, S. P. & Holst, Jens Juul, Jun 1994, In: Scandinavian Journal of Gastroenterology. 29, 6, p. 501-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Glucagon-like peptide-1, a new hormone of the entero-insular axis

    Ørskov, Cathrine, Aug 1992, In: Diabetologia. 35, 8, p. 701-11 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  45. Published

    Glucagon-like peptide-1, a new hormone of the enteroinsular axis

    Ørskov, Cathrine, 1992, In: Diabetologia. 35, p. 701-711

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine

    Hansen, L., Deacon, Carolyn F., Ørskov, Cathrine & Holst, Jens Juul, Nov 1999, In: Molecular Endocrinology. 140, 11, p. 5356-63 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Glucagonlike peptide-I-(7-36)-amide receptors only in islets of Langerhans

    Ørskov, Cathrine & Poulsen, S. S., 1991, In: Diabetes, The American Diabetes Association. Vol 40, no.10, p. 1292-1296

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Glucagonlike peptide-I-(7-36)-amide receptors only in islets of Langerhans. Autoradiographic survey of extracerebral tissues in rats

    Ørskov, Cathrine & Poulsen, Steen Seier, Oct 1991, In: Diabetes. 40, 10, p. 1292-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients

    Creutzfeldt, W. O., Kleine, N., Willms, B., Ørskov, Cathrine, Holst, Jens Juul & Nauck, M. A., Jun 1996, In: Diabetes Care. Supplement. 19, 6, p. 580-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation

    Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Nicolaisen, T. S., Carl, Christian Strini, Sjøberg, K. A., Raun, Steffen Henning, Klein, A. B., Sanchez-Quant, E., Langer, J., Ørskov, Cathrine, Clemmensen, Christoffer, Tschöp, M. H., Richter, Erik A., Kiens, Bente & Kleinert, Maximilian, 2020, In: Journal of Lipid Research. 61, 1, p. 10-19 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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