Carsten Haagen Nielsen

Carsten Haagen Nielsen

Guest Researcher


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  1. Published

    18F-FDG and 18F-FLT-PET Imaging for Monitoring Everolimus Effect on Tumor-Growth in Neuroendocrine Tumors: Studies in Human Tumor Xenografts in Mice

    Johnbeck, C. B., Wessel, Mette Munk, Nielsen, Carsten Haagen, Hag, Anne Mette Fisker, Knigge, Ulrich & Kjær, Andreas, 2014, In: PLOS ONE. 9, 3, p. 1-8 8 p., e91387.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    In vivo imaging of therapy response to a novel Pan-HER antibody mixture using FDG and FLT positron emission tomography

    Nielsen, Carsten Haagen, Wessel, Mette Munk, Kristensen, L. K., Dahlman, A., Fröhlich, C., Jacobsen, H. J., Poulsen, T. T., Lantto, J., Horak, I. D., Kragh, M. & Kjær, Andreas, Oct 2015, In: OncoTarget. 6, 35, p. 37486-99 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A New Positron Emission Tomography (PET) Radioligand for Imaging Sigma-1 Receptors in Living Subjects

    James, M. L., Shen, B., Zavaleta, C. L., Nielsen, Carsten Haagen, Mésangeau, C., Vuppala, P. K., Chan, C., Avery, B. A., Fishback, J. A., Matsumoto, R. R., Gambhir, S. S., McCurdy, C. R. & Chin, F. T., 2012, In: Journal of Medicinal Chemistry. 55, 19, p. 8272-8282 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A blood biomarker for monitoring response to anti-EGFR therapy

    Hughes, N. P., Xu, L., Nielsen, Carsten Haagen, Chang, E., Hori, S. S., Natarajan, A., Lee, S., Kjær, Andreas, Kani, K., Wang, S. X., Mallick, P. & Gambhir, S. S., 2018, In: Cancer Biomarkers. 22, 2, p. 333-344 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A titratable two-step transcriptional amplification strategy for targeted gene therapy based on ligand-induced intramolecular folding of a mutant human estrogen receptor

    Chen, I. Y., Paulmurugan, R., Nielsen, Carsten Haagen, Wang, D. S., Chow, V., Robbins, R. C. & Gambhir, S. S., Apr 2014, In: Molecular Imaging and Biology. 16, 2, p. 224-34 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Affinity-Guided Conjugation to Antibodies for Use in Positron Emission Tomography

    Skovsgaard, M. B., Jeppesen, T. E., Mortensen, M. R., Nielsen, Carsten Haagen, Madsen, J., Kjær, Andreas & Gothelf, K. V., 2019, In: Bioconjugate Chemistry. 30, 3, p. 881-887

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Biodistribution of Ra-224 and its daughter Pb-212 after intraperitoneal infusion of Ra-224 labeled microparticles in rats

    Fonslet, J., Nielsen, Carsten Haagen, Kristensen, L. K., Jorstad, I. S., Lindland, K., Larsen, R. H., Bruland, O. S., Kjær, Andreas & Bonsdorff, T. B., Jul 2019, In: Cancer Research. 79, 13, 2 p., Abstract 3922.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  8. Published

    Bringing Radiotracing to Titanium-Based Antineoplastics: Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [45Ti](salan)Ti(dipic)

    Severin, G. W., Nielsen, Carsten Haagen, Jensen, A. I., Fonslet, J., Kjær, Andreas & Zhuravlev, F., 24 Sep 2015, In: Journal of Medicinal Chemistry. 58, 18, p. 7591-7595 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    CD4+ and CD8a+ PET imaging predicts response to novel PD-1 checkpoint inhibitor: studies of Sym021 in syngeneic mouse cancer models

    Kristensen, L. K., Fröhlich, C., Christensen, C., Melander, M. C., Poulsen, T. T., Galler, G. R., Lantto, J., Horak, I. D., Kragh, M., Nielsen, Carsten Haagen & Kjær, Andreas, 2019, In: Theranostics. 9, 26, p. 8221-8238

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

    Sustarsic, E. G., Ma, T., Lynes, M. D., Larsen, M., Karavaeva, I., Havelund, J. F., Nielsen, C. H., Jedrychowski, M. P., Moreno-Torres, M., Lundh, M., Plucinska, K., Jespersen, N. Z., Grevengoed, T. J., Kramar, B., Peics, J., Hansen, J. B., Shamsi, F., Forss, I., Neess, D., Keipert, S. & 24 others, Wang, J., Stohlmann, K., Brandslund, I., Christensen, C., Jørgensen, M. E., Linneberg, Allan René, Pedersen, Oluf Borbye, Kiebish, M. A., Qvortrup, Klaus, Han, X., Pedersen, Bente Klarlund, Jastroch, M., Mandrup, S., Kjær, Andreas, Gygi, S. P., Hansen, Torben, Gillum, M. P., Grarup, Niels, Emanuelli, Brice, Nielsen, S., Schéele, Camilla Charlotte Nielsen, Tseng, Y., Færgeman, N. J. & Gerhart-Hines, Zach, 2018, In: Cell Metabolism. 28, 1, p. 159-174.e11

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Chronic Kidney Disease-Induced Vascular Calcification Impairs Bone Metabolism

    Mace, M. L., Gravesen, E., Nordholm, A., Egstrand, S., Morevati, M., Nielsen, Carsten Haagen, Kjær, Andreas, Behets, G., D'Haese, P., Ølgaard, Klaus & Lewin, E., 2021, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 36, 3, p. 510-522 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Combination of [177Lu]Lu-DOTA-TATE Targeted Radionuclide Therapy and Photothermal Therapy as a Promising Approach for Cancer Treatment: In Vivo Studies in a Human Xenograft Mouse Model

    Simón, M., Jørgensen, Jesper Tranekjær, Khare, Harshvardhan, Christensen, Camilla Hell, Nielsen, Carsten Haagen & Kjær, Andreas, 2022, In: Pharmaceutics. 14, 6, p. 1-16 1284.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Development and characterization of a panel of orthotopic glioblastoma multiforme (GBM) patient-derived xenograft (PDX) mouse models for drug efficacy evaluation

    Nielsen, Carsten Haagen, Alfsen, M. Z., Wick, M. J., Rundle, M., Gudbergsson, J. M., Jensen, M. M., Kristensen, L. K., Juul, M. U., Papadopoulos, K. P. & Kjær, Andreas, Jul 2019, In: Cancer Research. 79, 13, 2 p., Abstract 89.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  14. Published

    Effect of inhibition of CBP-coactivated β-catenin-mediated Wnt signalling in uremic rats with vascular calcifications

    Gravesen, Eva, Nordholm, A., Mace, M., Morevati, M., Høgdall, Estrid Vilma Solyom, Nielsen, Carsten Haagen, Kjær, Andreas, Ølgaard, Klaus & Lewin, E., 2018, In: PLOS ONE. 13, 8, e0201936.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Evaluation of σ-1 receptor radioligand 18F-FTC-146 in rats and squirrel monkeys using PET

    James, M. L., Shen, B., Nielsen, Carsten Haagen, Behera, D., Buckmaster, C. L., Mesangeau, C., Zavaleta, C., Vuppala, P. K., Jamalapuram, S., Avery, B. A., Lyons, D. M., McCurdy, C. R., Biswal, S., Gambhir, S. S. & Chin, F. T., Jan 2014, In: Journal of Nuclear Medicine. 55, 1, p. 147-53 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Exogenous BMP7 in aortae of rats with chronic uremia ameliorates expression of profibrotic genes, but does not reverse established vascular calcification

    Gravesen, Eva, Lerche Mace, M., Nordholm, A., Hofman-Bang, J., Hruska, K., Nielsen, Carsten Haagen, Kjær, Andreas, Ølgaard, Klaus & Lewin, E., 2018, In: PLOS ONE. 13, 1, 18 p., e0190820.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    First-in-Human PET Imaging of Tissue Factor in Patients with Primary and Metastatic Cancers Using 18F-labeled Active-Site Inhibited Factor VII (18F-ASIS): Potential as Companion Diagnostic

    Loft, Mathias Hougaard, Christensen, C., Clausen, Malene Martini, Carlsen, Esben Andreas, Hansen, C. P., Kroman, Niels Thorndahl, Langer, Seppo W., Høgdall, Claus Kim, Madsen, J., Gillings, N., Nielsen, Carsten Haagen, Klausen, Thomas Levin, Holm, S., Loft, A., Berthelsen, A. K. & Kjær, Andreas, 2022, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 63, 12, p. 1871-1879

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    First-in-human uPAR PET: Imaging of Cancer Aggressiveness

    Persson, M., Skovgaard, D., Brandt-Larsen, M., Christensen, C., Madsen, J., Nielsen, Carsten Haagen, Røndbjerg, T. T., Klausen, Thomas Levin, Holm, S., Loft, A., Berthelsen, A. K., Ploug, Michael, Pappot, H., Brasso, K., Kroman, Niels Thorndahl, Højgaard, Liselotte & Kjær, Andreas, 2015, In: Theranostics. 5, 12, p. 1303-16 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Hypoxia-Inducible Factor-1α Expression in Macrophages Promotes Development of Atherosclerosis

    Pedersen, A. A., Pedersen, T. X., Junker, N., Christoffersen, Christina, Bartels, Emil Daniel, Madsen, M., Nielsen, Carsten Haagen & Nielsen, L. B., Sep 2016, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 36, 9, p. 1782-1790 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Imaging gene expression in human mesenchymal stem cells: from small to large animals

    Willmann, J. K., Paulmurugan, R., Rodriguez-Porcel, M., Stein, W., Brinton, T. J., Connolly, A. J., Nielsen, Carsten Haagen, Lutz, A. M., Lyons, J., Ikeno, F., Suzuki, Y., Rosenberg, J., Chen, I. Y., Wu, J. C., Yeung, A. C., Yock, P., Robbins, R. C. & Gambhir, S. S., Jul 2009, In: Radiology. 252, 1, p. 117-27 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    ImmunoPET and T cell labeling for in vivo monitoring of immunotherapy: Development of CD8 Fab(2)' and Fab tracers for immunoPET and direct labeling of T cells for in vivo tracking

    Christensen, C., Kristensen, L. K., Nielsen, Carsten Haagen & Kjær, Andreas, Jul 2019, In: Cancer Research. 79, 13, 2 p., Abstract 1133:.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  22. Published

    Indirect imaging of cardiac-specific transgene expression using a bidirectional two-step transcriptional amplification strategy

    Chen, I. Y., Gheysens, O., Ray, S., Wang, Q., Padmanabhan, P., Paulmurugan, R., Loening, A. M., Rodriguez-Porcel, M., Willmann, J. K., Sheikh, A. Y., Nielsen, Carsten Haagen, Hoyt, G., Contag, C. H., Robbins, R. C., Biswal, S., Wu, J. C. & Gambhir, S. S., 2010, In: Gene Therapy (Basingstoke). 17, 7, p. 827-38 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Lewis and AB0 blood group-phenotypes in periodontitis, cardiovascular disease, obesity and stroke

    Enevold, C., Nielsen, Carsten Haagen, Molbo, Drude, Lund, Rikke, Bendtzen, K., Fiehn, Nils-Erik & Holmstrup, Palle, 2019, In: Scientific Reports. 9, 1, 7 p., 6283.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

    Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, Orchard, W., Willemsen, N., Jespersen, N. Z., Lundh, M., Sustarsic, E. G., Hallgren, C. M., Frost, M., McGonigle, S., Isidor, Marie Sophie, Broholm, C., Pedersen, Oluf Borbye, Hansen, Jacob B., Grarup, Niels, Hansen, Torben, Kjær, Andreas, Granneman, J. G., Babu, M. M., Calebiro, D., Nielsen, S., Rydén, M., Soccio, R., Rensen, P. C. N., Treebak, Jonas Thue, Schwartz, Thue W., Emanuelli, Brice, Bartolomucci, A., Pfeifer, A., Zechner, R., Schéele, Camilla Charlotte Nielsen, Mandrup, S. & Gerhart-Hines, Z., 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Matrix-insensitive protein assays push the limits of biosensors in medicine

    Gaster, R. S., Hall, D. A., Nielsen, Carsten Haagen, Osterfeld, S. J., Yu, H., Mach, K. E., Wilson, R. J., Murmann, B., Liao, J. C., Gambhir, S. S. & Wang, S. X., 2009, In: Nature Medicine. 15, 11, p. 1327-1332 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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