Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- 2011
- Published
Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus
Stephens, J. W., Bodvarsdottir, T. B., Wareham, K., Prior, S. L., Bracken, R. M., Lowe, G. D., Rumley, A., Dunseath, G., Luzio, S., Deacon, Carolyn F., Holst, Jens Juul & Bain, S. C., Nov 2011, In: Diabetes Research and Clinical Practice. 94, 2, p. 199-206 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon antagonism as a potential therapeutic target in type 2 diabetes
Bagger, J. I., Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, Tina, Nov 2011, In: Diabetes, Obesity and Metabolism. 13, 11, p. 965-971 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Foetal proglucagon processing in relation to adult appetite control: lessons from a transplantable rat glucagonoma with severe anorexia
Jensen, P. B., Larsen, P. J., Karlsen, C., Jensen, H. I., Holst, Jens Juul & Madsen, O. D., Oct 2011, In: Diabetes, Obesity and Metabolism. 13 , Suppl. 1, p. 60-68 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of glucagon secretion by incretins
Holst, Jens Juul, Christensen, M., Lund, A., de Heer, J., Svendsen, B., Kielgast, U. & Knop, Filip Krag, Oct 2011, In: Diabetes, Obesity and Metabolism. 13 , Suppl 1, p. 89-94 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying, glucose metabolism and gut hormones: evaluation of a common preoperative carbohydrate beverage
Vermeulen, M. A. R., Richir, M. C., Garretsen, M. K., van Schie, A., Ghatei, M. A., Holst, Jens Juul, Heijboer, A. C., Uitdehaag, B. M. J., Diamant, M., Eekhoff, E. M. W., van Leeuwen, P. A. M. & Ligthart-Melis, G. C., Sep 2011, In: Nutrition. 27, 9, p. 897-903 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial insulin secretion after gastric bypass surgery: the role of glucagon-like peptide 1
Holst, Jens Juul, Sep 2011, In: Diabetes. 60, 9, p. 2203-2205 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Administration of a dipeptidyl peptidase IV inhibitor enhances the intestinal adaptation in a mouse model of short bowel syndrome
Okawada, M., Holst, Jens Juul & Teitelbaum, D. H., Aug 2011, In: Surgery. 150, 2, p. 217-223 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormone and insulin responses to oral versus intravenous lipid administration in humans
Lindgren, O., Carr, R. D., Deacon, Carolyn F., Holst, Jens Juul, Pacini, G., Mari, A. & Ahrén, B., Aug 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 8, p. 2519-2524 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of inverse relationship between pulsatile insulin and glucagon secretion in patients with type 2 diabetes
Menge, B. A., Grüber, L., Jørgensen, S. M., Deacon, Carolyn F., Schmidt, W. E., Veldhuis, J. D., Holst, Jens Juul & Meier, J. J., Aug 2011, In: Diabetes. 60, 8, p. 2160-2168 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiological and pharmacological mechanisms through which the DPP-4 inhibitor sitagliptin regulates glycemia in mice
Waget, A., Cabou, C., Masseboeuf, M., Cattan, P., Armanet, M., Karaca, M., Castel, J., Garret, C., Payros, G., Maida, A., Sulpice, T., Holst, Jens Juul, Drucker, D. J., Magnan, C. & Burcelin, R., Aug 2011, In: Endocrinology. 152, 8, p. 3018-3029 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissociated incretin hormone response to protein versus fat ingestion in obese subjects
Lindgren, O., Carr, R., Holst, Jens Juul, Deacon, Carolyn F. & Ahren, B., Jul 2011, In: Diabetes, Obesity and Metabolism Online. 13, 9, p. 863-865 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four weeks of treatment with liraglutide reduces insulin dose without loss of glycemic control in type 1 diabetic patients with and without residual beta-cell function
Kielgast, U., Krarup, T., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jul 2011, In: Diabetes Care. 34, 7, p. 1463-1468 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glutamine reduces postprandial glycemia and augments the glucagon-like peptide-1 response in type 2 diabetes patients
Samocha-Bonet, D., Wong, O., Synnott, E., Piyaratna, N., Douglas, A., Gribble, F. M., Holst, Jens Juul, Chisholm, D. J. & Greenfield, J. R., Jul 2011, In: Journal of Nutrition. 141, 7, p. 1233-1238 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KU bestemmer selv over sin forskning
Wewer, Ulla M., Holst, Jens Juul, Schwartz, Thue W. & Quistorff, B., 2 Jun 2011, In: Universitetsavisen.Research output: Contribution to journal › Contribution to newspaper - Comment/debate › Communication
- Published
Inhibition of glucagon secretion by GLP-1 agonists and DPP4 inhibitors
Hansen, M., Juul Hare, K., Holst, Jens Juul & Knop, Filip Krag, Jun 2011, In: Journal of Clinical Metabolism & Diabetes. 2, 2, p. 7-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An overview of once-weekly glucagon-like peptide-1 receptor agonists--available efficacy and safety data and perspectives for the future
Madsbad, Sten, Kielgast, U., Asmar, M., Deacon, Carolyn F., Torekov, Signe Sørensen & Holst, Jens Juul, May 2011, In: Diabetes, Obesity and Metabolism. 13, 5, p. 394-407 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antidiabetic actions of endogenous and exogenous GLP-1 in type 1 diabetic patients with and without residual ß-cell function
Kielgast, U., Holst, Jens Juul & Madsbad, Sten, May 2011, In: Diabetes. 60, 5, p. 1599-1607 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of Incretin Effect Is a Specific, Important, and Early Characteristic of Type 2 Diabetes
Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, May 2011, In: Diabetes Care. 34, Supplement 2, p. S251-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IL-6 has no acute effect on the regulation of urea synthesis in vivo in rats
Thomsen, K., Aagaard, N. K., Grønbæk, H., Holst, Jens Juul, Jessen, N., Frystyk, J. & Vilstrup, H., Apr 2011, In: Scandinavian Journal of Clinical & Laboratory Investigation. 71, 2, p. 150-156 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition de la sécrétion du glucagon par les antagonistes du GLP-1 et les inhibiteurs de la DPP-4
Hansen, M., Knop, Filip Krag & Holst, Jens Juul, Apr 2011, In: Medecine des Maladies Metaboliques. 5, 2Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma levels of glucagon like peptide-1 associate with diastolic function in elderly men
Nathanson, D., Zethelius, B., Berne, C., Lind, L., Andrén, B., Ingelsson, E., Holst, Jens Juul & Nyström, T., Mar 2011, In: Diabetic Medicine. 28, 3, p. 301-305 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test
Gjesing, A. P., Kjems, L. L., Vestmar, M. A., Grarup, N., Linneberg, Allan René, Deacon, Carolyn F., Holst, Jens Juul, Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: Diabetologia. 54, 1, p. 103-10 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of PCSK1 Variants on Waist, Waist-Hip Ratio and Glucose Metabolism Is Modified by Sex and Glucose Tolerance Status
Gjesing, A. P., Vestmar, M. A., Jørgensen, T., Heni, M., Holst, Jens Juul, Witte, D. R., Hansen, Torben & Pedersen, Oluf Borbye, 1 Jan 2011, In: P L o S One. 6, 9, p. e23907 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans
Hansen, K. B., Rosenkilde, Mette, Knop, Filip Krag, Wellner, N., Diep, T. A., Rehfeld, Jens Frederik, Andersen, U. B., Holst, Jens Juul & Hansen, Harald S., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 9, p. E1409-17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A low glycemic index diet does not affect postprandial energy metabolism but decreases postprandial insulinemia and increases fullness ratings in healthy women
Krog-Mikkelsen, I., Sloth, B., Dimitrov, D., Tetens, Inge , Björck, I., Flint, A., Holst, Jens Juul, Astrup, A., Elmstähl, H. & Raben, Anne, 2011, In: Journal of Nutrition. 141, 9, p. 1679-1684 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression
Wang, Q., Bailey, C. G., Ng, C., Tiffen, J., Thoeng, A., Minhas, V., Lehman, M. L., Hendy, S. C., Buchanan, G., Nelson, C. C., Rasko, J. E. J., Holst, J. & Holst, Jens Juul, 2011, In: Cancer Research. 71, 24, p. 7525-7536 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in Glucose Homeostasis after Roux-en-Y Gastric Bypass Surgery for Obesity at Day Three, Two Months, and One Year after Surgery: Role of Gut Peptides
Falkén, Y., Hellström, P. M., Holst, Jens Juul & Näslund, E., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 7, p. 2227-35 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Counter-regulatory hormone responses to spontaneous hypoglycaemia during treatment with insulin Aspart or human soluble insulin: a double-blinded randomized cross-over study
Brock Jacobsen, I., Vind, B. F., Korsholm, L., Flyvbjerg, A., Frystyk, J., Holst, Jens Juul, Beck-Nielsen, H. & Henriksen, J. E., 2011, In: Acta Physiologica (Print). 202, 3, p. 337-347 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delayed ß-cell response and glucose intolerance in young women with Turner syndrome
Hjerrild, B. E., Holst, Jens Juul, Juhl, C., Christiansen, J. S., Schmitz, O. & Gravholt, C. H., 2011, In: B M C Endocrine Disorders. 11, p. 11-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs
Hjøllund, K. R., Deacon, Carolyn F. & Holst, Jens Juul, 2011, In: Diabetologia. 54, 8, p. 2206-8 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Dose response of subcutaneous GLP-1 infusion in patients with type 2 diabetes
Torekov, Signe Sørensen, Kipnes, M. S., Harley, R. E., Holst, Jens Juul & Ehlers, M. R., 2011, In: Diabetes, Obesity and Metabolism. 13, 7, p. 639-43 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of saxagliptin on β-cell stimulation and insulin secretion in patients with type 2 diabetes
Henry, R. R., Smith, S., Schwartz, S., Mudaliar, S. R., Deacon, Carolyn F., Holst, Jens Juul, Duan, R. Y., Chen, R. S. & List, J. F., 2011, In: Diabetes, Obesity and Metabolism. 13, 9, p. 850-858 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction
Lønborg, Jacob Thomsen, Vejlstrup, N., Kelbæk, H., Bøtker, H. E., Kim, W. Y., Mathiasen, A. B., Jørgensen, E., Helqvist, S., Saunamäki, K., Clemmensen, P., Holmvang, Lene, Thuesen, L., Krusell, L. R., Jensen, J. S., Køber, Lars Valeur, Treiman, M., Holst, Jens Juul & Engstrøm, Thomas, 2011, In: European Heart Journal. 33, 12, p. 1491-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP does not potentiate the antidiabetic effects of GLP-1 in hyperglycemic patients with type 2 diabetes
Mentis, N., Vardarli, I., Köthe, L. D., Holst, Jens Juul, Deacon, Carolyn F., Theodorakis, M., Meier, J. J. & Nauck, M. A., 2011, In: Diabetes. 60, 4, p. 1270-1276 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric bypass and duodenal and gastric feeding: a comment to Hansen et al
Jorgensen, N. B., Dirksen, C., Holst, Jens Juul & Madsbad, Sten, 2011, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 301, 5, p. G938-G9389 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying of orally administered glucose solutions and incretin hormone responses are unaffected by laparoscopic adjustable gastric banding
Usinger, Lotte, Hansen, K. B., Kristiansen, V. B., Larsen, S., Holst, Jens Juul & Knop, Filip Krag, 2011, In: Obesity Surgery. 21, 5, p. 625-32 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation within the TRPM5 locus associates with prediabetic phenotypes in subjects at increased risk for type 2 diabetes
Ketterer, C., Müssig, K., Heni, M., Dudziak, K., Randrianarisoa, E., Wagner, R., Machicao, F., Stefan, N., Holst, Jens Juul, Fritsche, A., Häring, H. & Staiger, H., 2011, In: Metabolism. 60, 9, p. 1325-1333 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon like-peptide 1 receptor and the liver
Pedersen, Jens & Holst, Jens Juul, 2011, In: Liver international : official journal of the International Association for the Study of the Liver. 31, 9, p. 1243-5 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 2 (Glp-2) stimulates intestinal function during weaning
Thymann, Thomas, Huërou-Luron, I. L., Petersen, Y. M., Hedemann, M. S., Elnif, J., Jensen, B. B., Hartmann, Bolette, Holst, Jens Juul & Sangild, Per Torp, 2011, 44th annual meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition, 2011: programme and abstract booklet. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), p. 202 1 p.Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research
- Published
Glucagon-like peptide-2 (GLP-2) increases small intestinal blood flow and mucosal growth in ruminating calves
Taylor-Edwards, C. C., Burrin, D. G., Holst, Jens Juul, McLeod, K. R. & Harmon, D. L., 2011, In: Journal of Dairy Science. 94, 2, p. 888-898 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide: a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans
Christensen, M., Vedtofte, L., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2011, In: Diabetes. 60, 12, p. 3103-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1
Torekov, S. S., Ma, L., Grarup, N., Hartmann, B., Hainerová, I. A., Kielgast, U., Kissow, H., Rosenkilde, M., Lebl, J., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Madsen, O. D., Wang, J., Linneberg, A., Madsbad, S., Holst, J. J., Hansen, T., Pedersen, O. & 1 others, , 2011, In: Diabetologia. 54, 11, p. 2820-31 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired regulation of the incretin effect in patients with type 2 diabetes
Bagger, J. I., Knop, Filip Krag, Lund, Asger Bach, drb459, drb459, Holst, Jens Juul & Vilsbøll, Tina, 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 3, p. 737-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased Postprandial GIP and Glucagon Responses, But Unaltered GLP-1 Response after Intervention with Steroid Hormone, Relative Physical Inactivity, And High-Calorie Diet in Healthy Subjects
Hansen, K. B., Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 2, p. 447-53 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased postprandial glycaemia, insulinemia, and lipidemia after 10 weeks’ sucrose-rich diet compared to an artificially sweetened diet: a randomised controlled trial
Raben, Anne, Møller, B. K., Flint, A., Vasilaris, T. H., Møller, A. C., Holst, Jens Juul & Astrup, A., 2011, In: Food & Nutrition Research. 55, 5961, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of DPP-4 with vildagliptin improved insulin secretion in response to oral as well as "isoglycemic" intravenous glucose without numerically changing the incretin effect in patients with type 2 diabetes
Vardarli, I., Nauck, M. A., Köthe, L. D., Deacon, Carolyn F., Holst, Jens Juul, Schweizer, A. & Foley, J. E., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 4, p. 945-954 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inkretiner
Vilsbøll, Tina & Holst, Jens Juul, 2011, Diabetes - sygdom, behandling og organisation. Hilsted, J., Borch-Johnsen, K. & Christiansen, J. S. (eds.). 2 ed. København: Munksgaard , p. 67-74 8 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Involvement of endogenous glucagon-like peptide-1 in regulation of gastric motility and pancreatic endocrine secretion
Witte, A., Grybäck, P., Jacobsson, H., Näslund, E., Hellström, P. M., Holst, Jens Juul, Hilsted, Linda & Schmidt, P. T., 2011, In: Scandinavian Journal of Gastroenterology. Supplement. 46, 4, p. 428-35 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide Treatment Is Associated with a Low Frequency and Magnitude of Antibody Formation with No Apparent Impact on Glycemic Response or Increased Frequency of Adverse Events: Results from the Liraglutide Effect and Action in Diabetes (LEAD) trials
Buse, J. B., Garber, A., Rosenstock, J., Schmidt, W. E., Brett, J. H., Videbæk, N., Holst, Jens Juul & Nauck, M., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 6, p. 1695-702 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lixisenatide for type 2 diabetes mellitus
Christensen, M., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2011, In: Expert Opinion on Investigational Drugs. 20, 4, p. 549-57 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4207
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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