Jens Høiriis Nielsen

Jens Høiriis Nielsen

Emeritus

Member of:

    ORCID: 0000-0001-8252-3048

    Introductory remarks on publicationslist

    153 scientific publications including 96 original papers, 3 patent applications and 54 reviews book chapters and conference proceedings. In addition app. abstracts and >250 invited lectures.


    Publication year:
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    51 - 100 out of 117Page size: 50
    1. 1998
    2. Published

      Characterization of the inhibitory effect of growth hormone on primary preadipocyte differentiation

      Hansen, L. H., Madsen, B., Teisner, B., Nielsen, Jens Høiriis & Billestrup, Nils, Aug 1998, In: Molecular endocrinology (Baltimore, Md.). 12, 8, p. 1140-9 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Molecular mechanism of growth hormone signalling

      Billestrup, Nils, Hansen, J. A., Hansen, L. H., Møldrup, A., Galsgaard, E. D. & Nielsen, Jens Høiriis, Apr 1998, In: Endocrine Journal. 45 Suppl, p. S41-5

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling

      Gromada, J., Bokvist, K., Ding, W. G., Holst, Jens Juul, Nielsen, Jens Høiriis & Rorsman, P., 1998, In: Diabetes. 47, 1, p. 57-65 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. 1997
    6. Published

      Beta-cell ontogeny: growth and death

      Corbett, J., Serup, Palle, Bonner-Weir, S. & Nielsen, Jens Høiriis, Oct 1997, In: Diabetologia. 40 Suppl 3, p. B27-32

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Growth hormone and prolactin stimulate the expression of rat preadipocyte factor-1/delta-like protein in pancreatic islets: molecular cloning and expression pattern during development and growth of the endocrine pancreas

      Carlsson, C., Tornehave, D., Lindberg, K., Galante, P., Billestrup, Nils, Michelsen, B., Larsson, L. I. & Nielsen, Jens Høiriis, Sep 1997, In: Endocrinology. 138, 9, p. 3940-8 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      The role of GH receptor tyrosine phosphorylation in Stat5 activation

      Hansen, J. A., Hansen, Lars Hestbjerg, Wang, X., Kopchick, J. J., Gouilleux, F., Groner, B., Møldrup, A., Galsgaard, E. D., Nielsen, Jens Høiriis & Billestrup, Nils, Jun 1997, In: Journal of Molecular Endocrinology. 18, 3, p. 213-21 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. 1996
    10. Published

      Identification of a growth hormone-responsive STAT5-binding element in the rat insulin 1 gene

      Galsgaard, E. D., Gouilleux, F., Groner, B., Serup, Palle, Billestrup, Nils & Nielsen, Jens Høiriis, Jun 1996, In: Molecular endocrinology (Baltimore, Md.). 10, 6, p. 652-60 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Identification of tyrosine residues in the intracellular domain of the growth hormone receptor required for transcriptional signaling and Stat5 activation

      Hansen, L. H., Wang, X., Kopchick, J. J., Bouchelouche, P., Galsgaard, E. D., Nielsen, Jens Høiriis & Billestrup, Nils, 24 May 1996, In: The Journal of Biological Chemistry. 271, 21, p. 12669-73 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Interleukin-1 beta-induced nitric oxide production from isolated rat islets is modulated by D-glucose and 3-isobutyl-1-methyl xanthine

      Andersen, H. U., Mauricio, D., Karlsen, A. E., Mandrup-Poulsen, Thomas, Nerup, J. & Nielsen, Jens Høiriis, Feb 1996, In: European Journal of Endocrinology. 134, 2, p. 251-9 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. 1995
    14. Published

      Requirement of tyrosine residues 333 and 338 of the growth hormone (GH) receptor for selected GH-stimulated function

      Lobie, P. E., Allevato, G., Norstedt, G., Billestrup, Nils & Nielsen, Jens Høiriis, 15 Sep 1995, In: The Journal of Biological Chemistry. 270, 37, p. 21745-50 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Molecular dissection of the growth hormone receptor. Identification of distinct cytoplasmic domains corresponding to different signaling pathways

      Billestrup, Nils, Allevato, G., Møldrup, A., Galsgaard, E. D., Amstrup, J., Hansen, J. A., Svensson, C. & Nielsen, Jens Høiriis, 7 Sep 1995, In: Annals of the New York Academy of Sciences. 766, p. 481-3 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Identification of phenylalanine 346 in the rat growth hormone receptor as being critical for ligand-mediated internalization and down-regulation

      Allevato, G., Billestrup, Nils, Goujon, L., Galsgaard, E. D., Norstedt, G., Postel-Vinay, M. C., Kelly, P. A. & Nielsen, Jens Høiriis, 21 Jul 1995, In: The Journal of Biological Chemistry. 270, 29, p. 17210-4 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Growth hormone receptor C-terminal domains required for growth hormone-induced intracellular free Ca2+ oscillations and gene transcription

      Billestrup, Nils, Bouchelouche, P., Allevato, G., Ilondo, M. & Nielsen, Jens Høiriis, 28 Mar 1995, In: Proceedings of the National Academy of Sciences of the United States of America. 92, 7, p. 2725-9 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. 1994
    19. Published

      Identification of intracellular domains in the growth hormone receptor involved in signal transduction

      Billestrup, Nils, Allevato, G., Norstedt, G., Møldrup, A. & Nielsen, Jens Høiriis, Jul 1994, In: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 206, 3, p. 205-9 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Cytoplasmic sequences of the growth hormone receptor necessary for signal transduction

      Goujon, L., Allevato, G., Simonin, G., Paquereau, L., Le Cam, A., Clark, J., Djiane, J., Postel-Vinay, M. C., Nielsen, Jens Høiriis & Edery, M., 1 Feb 1994, In: Proceedings of the National Academy of Sciences of the United States of America. 91, 3, p. 957-61 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. 1993
    22. Published

      Effects of sex and pregnancy hormones on growth hormone and prolactin receptor gene expression in insulin-producing cells

      Møldrup, A., Petersen, E. D. & Nielsen, Jens Høiriis, Sep 1993, In: Endocrinology. 133, 3, p. 1165-72 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Analysis of proinsulin and its conversion products by reversed-phase high-performance liquid chromatography

      Linde, S., Welinder, B. S. & Nielsen, Jens Høiriis, 5 May 1993, In: Journal of Chromatography A. 614, 2, p. 185-204 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Growth of the endocrine pancreas: the role of somatolactogenic hormones and receptors

      Billestrup, Nils, Møldrup, A., Allevato, G., Petersen, Erik Brinch, Pedersen, Johan, Hansen, J. A. & Nielsen, Jens Høiriis, Feb 1993, In: Biochemical Society Transactions. 21, 1, p. 146-9 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. 1992
    26. Published

      Evidence for association of the cloned liver growth hormone receptor with a tyrosine kinase

      Wang, X., Uhler, M. D., Billestrup, Nils, Norstedt, G., Talamantes, F., Nielsen, Jens Høiriis & Carter-Su, C., 25 Aug 1992, In: The Journal of Biological Chemistry. 267, 24, p. 17390-6 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      The role of growth hormone and prolactin in beta cell growth and regeneration

      Nielsen, Jens Høiriis, Møldrup, A., Billestrup, Nils, Petersen, E. D., Allevato, G. & Stahl, M., 1992, Pancreatic islet cell regeneration and growth. Vol. 321. p. 9-17; discussion 19-20 (Advances in Experimental Medicine and Biology).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    28. 1991
    29. Published

      Growth hormone action in rat insulinoma cells expressing truncated growth hormone receptors

      Møldrup, A., Allevato, G., Dyrberg, T., Billestrup, Nils & Nielsen, Jens Høiriis, 15 Sep 1991, In: The Journal of Biological Chemistry. 266, 26, p. 17441-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      The stimulatory effect of growth hormone, prolactin, and placental lactogen on beta-cell proliferation is not mediated by insulin-like growth factor-I

      Billestrup, Nils & Nielsen, Jens Høiriis, Aug 1991, In: Endocrinology. 129, 2, p. 883-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Islet amyloid polypeptide and insulin expression are controlled differently in primary and transformed islet cells

      Madsen, O. D., Michelsen, B. T., Westermark, P., Betsholtz, C., Nishi, M., Steiner, D. F. & Nielsen, Jens Høiriis, Jan 1991, In: Molecular endocrinology (Baltimore, Md.). 5, 1, p. 143-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Transport of ascorbic acid and dehydroascorbic acid by pancreatic islet cells from neonatal rats

      Zhou, A., Farver, O., Thorn, N. A. & Nielsen, Jens Høiriis, 1991, In: Biochemical Journal. 274 ( Pt 3), p. 739-44 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. 1990
    34. Published

      Introduction of exogenous growth hormone receptors augments growth hormone-responsive insulin biosynthesis in rat insulinoma cells

      Billestrup, Nils, Møldrup, A., Serup, Palle, Mathews, L. S., Norstedt, G. & Nielsen, Jens Høiriis, Sep 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 18, p. 7210-4 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      High-performance liquid chromatography of rat and mouse islet polypeptides: potential risk of oxidation of methionine residues during sample preparation

      Linde, S., Hansen, Birger, Welinder, B. S. & Nielsen, Jens Høiriis, 24 Aug 1990, In: Journal of Chromatography A. 530, 1, p. 29-37 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Rat insulinoma cells express both a 115-kDa growth hormone receptor and a 95-kDa prolactin receptor structurally related to the hepatic receptors

      Møldrup, A., Billestrup, Nils & Nielsen, Jens Høiriis, 25 May 1990, In: The Journal of Biological Chemistry. 265, 15, p. 8686-90 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Effect of 5'-flanking sequence deletions on expression of the human insulin gene in transgenic mice

      Fromont-Racine, M., Bucchini, D., gjc556, gjc556, Desbois, P., Linde, S., Saulnier, C., Ripoche, M. A., Jami, J., Pictet, R. & Nielsen, Jens Høiriis, May 1990, In: Molecular endocrinology (Baltimore, Md.). 4, 5, p. 669-77 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Effect of growth hormone and serum on the expression of the proto-oncogenes c-jun and c-fos in insulin producing cells

      Petersen, E. D., Billestrup, Nils & Nielsen, Jens Høiriis, 1990, In: Biomedica Biochimica Acta. 49, 12, p. 1171-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Expression of the growth hormone receptor gene in insulin producing cells

      Møldrup, A., Billestrup, Nils & Nielsen, Jens Høiriis, 1990, In: Biomedica Biochimica Acta. 49, 12, p. 1151-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. 1989
    41. Published

      Direct long-term effects of L-asparaginase on rat and human pancreatic islets

      Clausen, N. & Nielsen, Jens Høiriis, Aug 1989, In: Pediatric Research. 26, 2, p. 158-61 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Multiple growth hormone-binding proteins are expressed on insulin-producing cells

      Møldrup, A., Billestrup, Nils, Thorn, N. A., Lernmark, A. & Nielsen, Jens Høiriis, Aug 1989, In: Molecular endocrinology (Baltimore, Md.). 3, 8, p. 1173-82 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Pancreatic hormones are expressed on the surfaces of human and rat islet cells through exocytotic sites

      Larsson, L. I., Hutton, J. C., Madsen, O. D. & Nielsen, Jens Høiriis, Feb 1989, In: European Journal of Cell Biology. 48, 1, p. 45-51 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Supravital dithizone staining in the isolation of human and rat pancreatic islets

      Hansen, W. A., Christie, M. R., Kahn, R., Norgaard, A., Abel, I., Petersen, A. M., Jorgensen, D. W., Baekkeskov, S., Nielsen, Jens Høiriis & Lernmark, A., Feb 1989, In: Diabetes Research: Clinical & Experimental. 10, 2, p. 53-7 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Reversed-phase high-performance liquid chromatographic analyses of insulin biosynthesis in isolated rat and mouse islets

      Linde, S., Hansen, B. A., Welinder, B. S. & Nielsen, Jens Høiriis, 13 Jan 1989, In: Journal of Chromatography A. 462, p. 243-54 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Growth hormone is a growth factor for the differentiated pancreatic beta-cell

      Linde, S., Welinder, B. S., Billestrup, Nils, Madsen, O. D. & Nielsen, Jens Høiriis, Jan 1989, In: Molecular endocrinology (Baltimore, Md.). 3, 1, p. 165-73 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Mechanisms of pancreatic beta-cell growth and regeneration: studies on rat insulinoma cells

      Nielsen, Jens Høiriis, 1989, In: Experimental and Clinical Endocrinology and Diabetes. Supplement. 93, 2-3, p. 277-85 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. 1988

    49. Gene probes to detect cross-culture contamination in hormone producing cell lines

      Matsuba, I., Lernmark, A., Madsen, O. D., Michelsen, B., Nielsen, Jens Høiriis, Scholler, J., Vissing, Henrik, Welinder, B., Tommerup, Niels & Mikkelsen, M., Nov 1988, In: In Vitro Cellular & Developmental Biology. 24, 11, p. 1071-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      The bimodal effect of interleukin 1 on rat pancreatic beta-cells--stimulation followed by inhibition--depends upon dose, duration of exposure, and ambient glucose concentration

      Spinas, G. A., Palmer, J. P., Mandrup-Poulsen, Thomas, Andersen, Heine, Nerup, J. & Nielsen, Jens Høiriis, Oct 1988, In: Acta Endocrinologica. 119, 2, p. 307-11 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Truncated glucagon-like peptide-1 (proglucagon 78-107 amide), an intestinal insulin-releasing peptide, has specific receptors on rat insulinoma cells (RIN 5AH)

      Ørskov, Cathrine & Nielsen, Jens Høiriis, 29 Feb 1988, In: FEBS Letters. 229, 1, p. 175-8 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Effect of interleukin-1 on the biosynthesis of proinsulin and insulin in isolated rat pancreatic islets

      Hansen, B. S., Linde, S., Spinas, G. A., Welinder, B. S., Mandrup-Poulsen, Thomas, Nerup, J. & Nielsen, Jens Høiriis, 1988, In: Biomedica Biochimica Acta. 47, 4-5, p. 305-9 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. 1987
    54. Published

      Tissue-type plasminogen activator in somatostatin cells of rat pancreas and hypothalamus

      Kristensen, P., Larsson, L. I., Danø, K. & Nielsen, Jens Høiriis, Dec 1987, In: Endocrinology. 121, 6, p. 2238-44 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. Published

      Interleukin 1 dose-dependently affects the biosynthesis of (pro)insulin in isolated rat islets of Langerhans

      Spinas, G. A., Hansen, B. S., Linde, S., Kastern, W., Mølvig, J., Mandrup-Poulsen, Thomas, Dinarello, C. A., Nerup, J. & Nielsen, Jens Høiriis, Jul 1987, In: Diabetologia. 30, 7, p. 474-80 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      Islet cytotoxicity of interleukin 1. Influence of culture conditions and islet donor characteristics

      Mandrup-Poulsen, Thomas, Spinas, G. A., Prowse, S. J., Hansen, B. S., Jørgensen, D. W., Bendtzen, K., Nerup, J. & Nielsen, Jens Høiriis, May 1987, In: Diabetes. 36, 5, p. 641-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      Ultrastructural studies of time-course and cellular specificity of interleukin-1 mediated islet cytotoxicity

      Mandrup-Poulsen, Thomas, Egeberg, J., Nerup, J., Bendtzen, K., Dinarello, C. A. & Nielsen, Jens Høiriis, Apr 1987, In: Acta pathologica, microbiologica, et immunologica Scandinavica. Section C, Immunology. 95, 2, p. 55-63 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. 1986
    59. Published

      Direct effects of cyclosporin A on human pancreatic beta-cells

      Mandrup-Poulsen, Thomas, Nerup, J. & Nielsen, Jens Høiriis, Sep 1986, In: Diabetes. 35, 9, p. 1049-52 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      Localization and biosynthesis of polyamines in insulin-producing cells

      Hougaard, D. M., Larsson, L. I. & Nielsen, Jens Høiriis, 15 Aug 1986, In: Biochemical Journal. 238, 1, p. 43-7 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. Published

      Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans

      Bendtzen, K., Mandrup-Poulsen, Thomas, Nerup, J., Dinarello, C. A., Svenson, M. & Nielsen, Jens Høiriis, 20 Jun 1986, In: Science (New York, N.Y.). 232, 4757, p. 1545-7 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    62. Published

      Mechanisms of pancreatic islet cell destruction. Dose-dependent cytotoxic effect of soluble blood mononuclear cell mediators on isolated islets of Langerhans

      Mandrup-Poulsen, Thomas, Bendtzen, K., Nerup, J., Egeberg, J. & Nielsen, Jens Høiriis, May 1986, In: Allergy. 41, 4, p. 250-9 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      Affinity-purified human interleukin I is cytotoxic to isolated islets of Langerhans

      Mandrup-Poulsen, Thomas, Bendtzen, K., Nerup, J., Dinarello, C. A., Svenson, M. & Nielsen, Jens Høiriis, Jan 1986, In: Diabetologia. 29, 1, p. 63-7 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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