Julien Ochala

Julien Ochala

Associate Professor - Promotion Programme

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    ORCID: 0000-0002-6358-2920

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    1. Published

      Mechanisms underlying the sparing of masticatory versus limb muscle function in an experimental critical illness model

      Aare, S., Ochala, Julien, Norman, H. S., Radell, P., Eriksson, L. I., Göransson, H., Chen, Y. W., Hoffman, E. P. & Larsson, L., Dec 2011, In: Physiological Genomics. 43, 24, p. 1334-1350 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Maintenance of muscle mass, fiber size, and contractile function in mice lacking the Z-disc protein myotilin

      Ochala, Julien, Carpn, O. & Larsson, L., 2009, In: Upsala Journal of Medical Sciences. 114, 4, p. 235-241 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Impairments in contractility and cytoskeletal organisation cause nuclear defects in nemaline myopathy

      Ross, J. A., Levy, Y., Ripolone, M., Kolb, J. S., Turmaine, M., Holt, M., Lindqvist, J., Claeys, K. G., Weis, J., Monforte, M., Tasca, G., Moggio, M., Figeac, N., Zammit, P. S., Jungbluth, H., Fiorillo, C., Vissing, J., Witting, N., Granzier, H., Zanoteli, E. & 3 others, Hardeman, E. C., Wallgren-Pettersson, C. & Ochala, Julien, 2019, In: Acta Neuropathologica. 138, 3, p. 477-495 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Human skeletal myopathy myosin mutations disrupt myosin head sequestration

      Carrington, G., Hau, A., Kosta, S., Dugdale, H. F., Muntoni, F., D’Amico, A., Van den Bergh, P., Romero, N. B., Malfatti, E., Vilchez, J. J., Oldfors, A., Pajusalu, S., Õunap, K., Giralt-Pujol, M., Zanoteli, E., Campbell, K. S., Iwamoto, H., Peckham, M. & Ochala, Julien, 2023, In: JCI insight. 8, 21, p. 1-19 e172322.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Gene expression and muscle fiber function in a porcine ICU model

      Banduseela, V. C., Ochala, Julien, Chen, Y. W., Göransson, H., Norman, H., Radell, P., Eriksson, L. I., Hoffman, E. P. & Larsson, L., Nov 2009, In: Physiological Genomics. 39, 3, p. 141-159 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Gender differences in human muscle and joint mechanical properties during plantar flexion in old age

      Ochala, Julien, Valour, D., Pousson, M., Lambertz, D. & Van Hoecke, J., May 2004, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 59, 5, p. 441-448 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Fine-regulation of myosin relaxed states in vertebrate muscle

      Thomsen, Elise Julie Melhedegaard, Sonne, A., Bertelsen, Mads Frost, Vermeulen, E., Ganswindt, A., Wang, T. & Ochala, Julien, 2022, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 36

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Factors underlying the early limb muscle weakness in acute quadriplegic myopathy using an experimental ICU porcine model

      Ochala, Julien, Ahlbeck, K., Radell, P. J., Eriksson, L. I. & Larsson, L., 2011, In: PLoS ONE. 6, 6, e20876.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Exploring the Role of PGC-1α in Defining Nuclear Organisation in Skeletal Muscle Fibres

      Ross, J. A., Pearson, A., Levy, Y., Cardel, B., Handschin, C. & Ochala, Julien, 1 Jun 2017, In: Journal of Cellular Physiology. 232, 6, p. 1270-1274 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Effects of a preferential myosin loss on Ca2+ activation of force generation in single human skeletal muscle fibres

      Ochala, Julien & Larsson, L., Apr 2008, In: Experimental Physiology. 93, 4, p. 486-495 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Effects of a R133W β-tropomyosin mutation on regulation of muscle contraction in single human muscle fibres

      Ochala, Julien, Li, M., Tajsharghi, H., Kimber, E., Tulinius, M., Oldfors, A. & Larsson, L., 1 Jun 2007, In: Journal of Physiology. 581, 3, p. 1283-1292 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Effect of strength training on musculotendinous stiffness in elderly individuals

      Ochala, Julien, Lambertz, D., Van Hoecke, J. & Pousson, M., May 2005, In: European Journal of Applied Physiology. 94, 1-2, p. 126-133 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Effect of PGC1-beta ablation on myonuclear organisation

      Beedour, R., Ross, J. A., Levy, Y. & Ochala, Julien, 1 Dec 2019, In: Journal of Muscle Research and Cell Motility. 40, 3-4, p. 335-341 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Early clinical and pre-clinical therapy development in Nemaline myopathy

      Fisher, G., Mackels, L., Markati, T., Sarkozy, A., Ochala, Julien, Jungbluth, H., Ramdas, S. & Servais, L., 28 Dec 2022, In: Expert Opinion On Therapeutic Targets. 26, 10, p. 853–867

      Research output: Contribution to journal › Review › Research › peer-review

    15. Published

      EMD 57033 partially reverses ventilator-induced diaphragm muscle fibre calcium desensitisation

      Ochala, Julien, Radell, P. J., Eriksson, L. I. & Larsson, L., Feb 2010, In: Pflugers Archiv European Journal of Physiology. 459, 3, p. 475-483 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Dystrophin restoration therapy improves both the reduced excitability and the force drop induced by lengthening contractions in dystrophic mdx skeletal muscle

      Roy, P., Rau, F., Ochala, Julien, Messéant, J., Fraysse, B., Lainé, J., Agbulut, O., Butler-Browne, G., Furling, D. & Ferry, A., 20 Jul 2016, In: Skeletal Muscle. 6, 1, 23.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Distinct underlying mechanisms of limb and respiratory muscle fiber weaknesses in nemaline myopathy

      Lindqvist, J., Cheng, A. J., Renaud, G., Hardeman, E. C. & Ochala, Julien, Jun 2013, In: Journal of Neuropathology and Experimental Neurology. 72, 6, p. 472-481 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Disrupted myosin cross-bridge cycling kinetics triggers muscle weakness in nebulin-related myopathy

      Ochala, Julien, Lehtokari, V. L., Iwamoto, H., Li, M., Feng, H. Z., Jin, J. P., Yagi, N., Wallgren-Pettersson, C., Pénisson-Besnier, I. & Larsson, L., Jun 2011, In: FASEB Journal. 25, 6, p. 1903-1913 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Diaphragm muscle weakness in an experimental porcine intensive care unit model

      Ochala, Julien, Renaud, G., Diez, M. L., Banduseela, V. C., Aare, S., Ahlbeck, K., Radell, P. J., Eriksson, L. I. & Larsson, L., 2011, In: PLoS ONE. 6, 6, e20558.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Defining the contribution of skeletal muscle pyruvate dehydrogenase α1 to exercise performance and insulin action

      Svensson, K., Dent, J. R., Tahvilian, S., Martins, V. F., Sathe, A., Ochala, Julien, Patel, M. S. & Schenk, S., Nov 2018, In: American Journal of Physiology - Endocrinology and Metabolism. 315, 5, p. E1034-E1045

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Defective regulation of contractile function in muscle fibres carrying an E41K β-tropomyosin mutation

      Ochala, Julien, Li, M., Ohlsson, M., Oldfors, A. & Larsson, L., 15 Jun 2008, In: Journal of Physiology. 586, 12, p. 2993-3004 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Current and future therapeutic approaches to the congenital myopathies

      Jungbluth, H., Ochala, Julien, Treves, S. & Gautel, M., Apr 2017, In: Seminars in Cell and Developmental Biology. 64, p. 191-200 10 p.

      Research output: Contribution to journal › Review › Research › peer-review

    23. Published

      Correction: Impaired adaptive response to mechanical overloading in dystrophic skeletal muscle (PLoS ONE)

      Joanne, P., Hourdé, C., Ochala, Julien, Caudéran, Y., Medja, F., Vignaud, A., Mouisel, E., Hadj-Said, W., Arandel, L., Garcia, L., Goyenvalle, A., Mounier, R., Zibroba, D., Sakamato, K., Butler-Browne, G., Agbulut, O. & Ferry, A., 27 Jun 2013, In: PLoS ONE. 8, 6

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    24. Published

      Congenital myopathy-causing tropomyosin mutations induce thin filament dysfunction via distinct physiological mechanisms

      Ochala, Julien, Gokhin, D. S., Pénisson-Besnier, I., Quijano-Roy, S., Monnier, N., Lunardi, J., Romero, N. B. & Fowler, V. M., Oct 2012, In: Human Molecular Genetics. 21, 20, p. 4473-4485 13 p., dds289.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Congenital myopathies: disorders of excitation-contraction coupling and muscle contraction

      Jungbluth, H., Treves, S., Zorzato, F., Sarkozy, A., Ochala, Julien, Sewry, C., Phadke, R., Gautel, M. & Muntoni, F., Mar 2018, In: Nature Reviews. Neurology. 14, 3, p. 151-167 17 p.

      Research output: Contribution to journal › Review › Research › peer-review

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