Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    GLP-1 and Intestinal Diseases

    Dal, Jenna Elizabeth Hunt, Holst, Jens Juul, Jeppesen, Palle Bekker & Kissow, Hannelouise, 2021, In: Biomedicines. 9, 4, 14 p., 383.

    Research output: Contribution to journalReviewResearchpeer-review

  2. Published

    Intestinal Growth in Glucagon Receptor Knockout Mice is Not Associated with the Formation of Aom/DSS-Induced Tumours

    Dal, Jenna Elizabeth Hunt, Yassin, M., Olsen, Jørgen, Windeløv, Johanne Agerlin, Galsgaard, Katrine Douglas, Holst, Jens Juul & Kissow, Hannelouise, 1 May 2019, In: Gastroenterology. 156, 6 (S1), 1 p., S-692.

    Research output: Contribution to journalConference abstract in journalResearch

  3. Published

    Dietary Fiber is Essential to Maintain L Cell Secretion and Intestinal Weight

    Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Holst, Jens Juul & Kissow, Hannelouise, 1 May 2019, In: Gastroenterology. 156, 6 (S1), p. S-477

    Research output: Contribution to journalConference abstract in journalResearch

  4. Published

    Dietary Fiber Is Essential to Maintain Intestinal Size, L-Cell Secretion, and Intestinal Integrity in Mice

    Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Schoonjans, K., Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Frontiers in Endocrinology. 12, 10 p., 640602.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Intestinal Growth in Glucagon Receptor Knockout Mice Is Not Associated With the Formation of AOM/DSS-Induced Tumors

    Dal, Jenna Elizabeth Hunt, Yassin, M., Olsen, Jørgen, Hartmann, Bolette, Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Frontiers in Endocrinology. 12, 7 p., 695145.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Pharmacological activation of TGR5 promotes intestinal growth via a GLP-2 dependent pathway in mice

    Dal, Jenna Elizabeth Hunt, Billeschou, Anna, Windeløv, Johanne Agerlin, Hartmann, Bolette, Ullmer, C., Holst, Jens Juul & Kissow, Hannelouise, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 6, p. G980-G987

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Glucose- and Bile Acid-Stimulated Secretion of Gut Hormones in the Isolated Perfused Intestine Is Not Impaired in Diet-Induced Obese Mice

    Dal, Jenna Elizabeth Hunt, Holst, Jens Juul & Jepsen, Sara Lind, 2022, In: Frontiers in Endocrinology. 13, 10 p., 884501.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Dietary impact on fasting and stimulated GLP-1 secretion in different metabolic conditions - a narrative review

    Huber, H., Schieren, A., Holst, Jens Juul & Simon, M., 2024, In: The American Journal of Clinical Nutrition. 119, 3, p. 599-627

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Increased Postprandial Response of Glucagon-Like Peptide-2 in Patients with Chronic Pancreatitis and Pancreatic Exocrine Insufficiency

    Hornum, Mads, Pedersen, J. F., Larsen, S., Olsen, O., Holst, Jens Juul & Knop, Filip Krag, 2010, In: Pancreatology. 10, 2-3, p. 201-207 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Secretion of neurotensin from isolated perfused porcine ileum

    Holst Pedersen, J., Knuthsen, S., Bernabei, M., Ørskov, Cathrine & Holst, Jens Juul, May 1988, In: Regulatory Peptides. 21, 1-2, p. 13-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The pathogenesis of non-insulin dependent diabetes mellitus involves a defective expression of the GIP receptor.

    Holst, Jens Juul, Gromada, J. L. & Nauck, M. A., 1997, In: Diabetologia. 40, p. 984-986

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    For debate: Are antidiabetic actions of DPP-IV inhibitors mediated by glucagon-like peptide- 1?

    Holst, Jens Juul & Deacon, Carolyn F., 2005, In: Diabetologia. 48, p. 612-615

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Enhancing insulin secretion: novel approaches to glucose control

    Holst, Jens Juul, 2004, In: Diabetes Voice. 49, p. 20-22

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Therapy of type 2 diabetes mellitus based on the actions of glucagon-like peptide-1.

    Holst, Jens Juul, 2002, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 18, 6, p. 430-41 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Treatment of type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors.

    Holst, Jens Juul, 2004, In: Expert Opinion on Emerging Drugs. 9, 1, p. 155-66 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The Gut: A Key to the Pathogenesis of Type 2 Diabetes?

    Holst, Jens Juul, Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Knop, Filip Krag, Aug 2017, In: Metabolic Syndrome and Related Disorders. 15, 6, p. 259-262 4 p.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Neuroprotective properties of GLP-1: theoretical and practical applications

    Holst, Jens Juul, Burcelin, R. & Nathanson, E., 2011, In: Current Medical Research and Opinion. 27, 3, p. 547-58 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Will GLP-1 treatment increase blood pressure? Summary and comment

    Holst, Jens Juul, 2003, In: Diabetes Monitor. 15, p. 15-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Mechanisms of surgical control of type 2 diabetes: GLP-1 is key factor

    Holst, Jens Juul & Madsbad, Sten, Jul 2016, In: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 12, 6, p. 1236-42 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Assays for Peptide Products of Somatostatin Gene Expression

    Holst, Jens Juul & Bersani, M., 1991, In: Methods in Neurosciences. 5, p. 3-22

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    From the Incretin Concept and the Discovery of GLP-1 to Today's Diabetes Therapy

    Holst, Jens Juul, 2019, In: Frontiers in Endocrinology. 10, 10 p., 260.

    Research output: Contribution to journalReviewResearchpeer-review

  22. Published

    Glucagon-like peptide-1 mediates the therapeutic actions of DPP-IV inhibitors

    Holst, Jens Juul & Deacon, Carolyn F., Apr 2005, In: Diabetologia. 48, 4, p. 612-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Searching for the physiological role of glucose-dependent insulinotropic polypeptide

    Holst, Jens Juul, Windeløv, Johanne Agerlin, Boer, G. A., Pedersen, Jens, Svendsen, B., Christensen, M., Torekov, Signe Sørensen, Asmar, M., Hartmann, Bolette & Nissen, A., 1 Apr 2016, In: Journal of Diabetes Investigation. 7, S1, p. 8-12 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Glucagon 100 years. Important, but still enigmatic

    Holst, Jens Juul, 2023, In: Peptides. 161, 6 p., 170942.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Glucagon-like peptide-1 (GLP-1) - A newly discovered Gl Hormone. Review.

    Holst, Jens Juul, 1994, In: Today in Medicine. Gastroenterology. 107, p. 1848-1855

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Posttranslational processing of proglucagon and postsecretory fate of proglucagon products.

    Holst, Jens Juul, Ørskov, C., Hartmann, B. & Deacon, Carolyn F., 1997, The Insulinotropic Gut Hormone Glucagon-like Peptide-1.. Basel: Karger, p. 24-48

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  27. Published

    Chap.10. Degradation of glucagons

    Holst, Jens Juul, 1991, Degradation of Bioactive Substances: Physiology and Pathophysiology. Boca Raton, Florida: CRC Press, p. 167-180

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  28. Published

    Actions of glucagon-like peptide-1 receptor ligands in the gut

    Holst, Jens Juul, Andersen, Daniel Bjørklund & Grunddal, Kaare Villum, 2022, In: British Journal of Pharmacology. 179, 4, p. 727-742

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    Roles of the Gut in Glucose Homeostasis

    Holst, Jens Juul, Gribble, F., Horowitz, M. & Rayner, C. K., Jun 2016, In: Diabetes Care. 39, 6, p. 884-92 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    GLP-1 receptor agonists: targeting both hyperglycaemia and disease processes in diabetes

    Holst, Jens Juul & Seino, Y., 2009, In: Diabetes Research and Clinical Practice. 85, 1, p. 1-3 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Semaglutide seems to be more effective the other GLP-1Ras

    Holst, Jens Juul & Madsbad, Sten, Dec 2017, In: Annals of Translational Medicine. 5, 24, 5 p., 505.

    Research output: Contribution to journalComment/debateResearch

  32. Published

    The incretin system in healthy humans: The role of GIP and GLP-1

    Holst, Jens Juul, 2019, In: Metabolism. 96, p. 46-55

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Glucagon-like peptide 1 - a new hormone which may change the treatment of non-insulin dependent diabetes mellitus

    Holst, Jens Juul & Ørskov, C., 1992, In: MedView. 6, p. 259-263

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans.

    Holst, Jens Juul & Gromada, J., 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 2, p. E199-206

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Effect of intestinal inhibitory peptides on vagally induced secretion from isolated perfused porcine pancreas

    Holst, Jens Juul, Rasmussen, T. N., Harling, H. & Schmidt, P., 1993, In: Pancreas. Vol. 8, no. 1, p. 80-87

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Isolated organs as replacements for vertebrate animals

    Holst, Jens Juul, 1994, Handbook of Laboratory Animal Science. USA: CRC Press, p. 397-408

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  37. Published

    Is there a place for incretin therapies in obesity and prediabetes?

    Holst, Jens Juul & Deacon, Carolyn F., 13 Feb 2013, In: Trends in Endocrinology and Metabolism. 24, 3, p. 145-152 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Neural regulation of pancreatic exocrine funktion

    Holst, Jens Juul, 1993, In: The Pancreas: Biology, Pathobiology an Disease. p. 381-402

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Glucagon and other proglucagon-derived peptides

    Holst, Jens Juul & Ørskov, Cathrine, 1994, Gut Peptides: Biochemistry and Physiology. New York: Raven Press, p. 305-340

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  40. Published

    Potential new approaches to modifying intestinal GLP-1 secretion in patients with type 2 diabetes mellitus: focus on bile acid sequestrants

    Holst, Jens Juul & McGill, M. A., 2012, In: Clinical Drug Investigation. 32, 1, p. 1-14 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Glucagon-like peptides 1 and 2, enteroglucagon, glicentin and oxyntomodulin

    Holst, Jens Juul, Deacon, Carolyn F., Hartmann, Bolette & Pedersen, Jens, 2013, Handbook of Biologically Active Peptides . Kastin, AJ. (ed.). 2 ed. Elsevier, p. 1241-1250 10 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  42. Published

    Erratum to semaglutide seems to be more effective the other GLP-1Ras

    Holst, Jens Juul & Madsbad, Sten, 2018, In: Annals of Translational Medicine. 6, 3, p. 74

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Non-insulin-dependent diabetes mellitus - new drugs?

    Holst, Jens Juul, 1997, In: Drug Discovery Today. 2, p. 128-129

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Somatostatin is an essential paracrine link in acid inhibition of gastrin secretion

    Holst, Jens Juul, Ørskov, Cathrine & Poulsen, S. S., 1992, In: Digestion. 51, p. 95-102

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Incretin based therapies: do they hold their promise?

    Holst, Jens Juul, 2012, In: Journal of Diabetes. 4, 1, p. 4-7 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Glucagon-like peptide 1 and inhibitors of dipeptidyl peptidase IV in the treatment of type 2 diabetes mellitus.

    Holst, Jens Juul & Deacon, Carolyn F., 2004, In: Current Opinion in Pharmacology. 4, 6, p. 589-96 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Neuromediators in the control of pancreatic secretion

    Holst, Jens Juul, 1993, Neuromediators in the control of pancreatic secretion. Torun: Polish Physiological Society, p. 72-78

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  48. Published

    New Lessons from the gut: Studies of the role of gut peptides in weight loss and diabetes resolution after gastric bypass and sleeve gastrectomy

    Holst, Jens Juul, Madsbad, Sten, Bojsen-Møller, Kirstine Nyvold, Dirksen, C. & Svane, M., 2024, In: Peptides. 176, 9 p., 171199.

    Research output: Contribution to journalReviewResearchpeer-review

  49. Published

    Gut hormones and intestinal function

    Holst, Jens Juul & Schmidt, P., 1994, The Gut as an Endocrine Organ. Clinics in Endocrinology and Metabolism, Vol 8. Bailliere, p. 137-164

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  50. Published

    What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists?

    Holst, Jens Juul, 2021, In: Cell Reports Medicine. 2, 5, 2 p., 100284.

    Research output: Contribution to journalComment/debateResearch

ID: 4207