Thomas Jespersen
Professor
Physiology of circulation, kidney and lung
Blegdamsvej 3, Building: 12-5-08
2200 København N
Denmark
Member of:
- Published
Kondo physics in tunable semicondouctor nanowire quantum dots
Jespersen, Thomas, Aagesen, M., Sørensen, Claus Birger, Lindelof, Poul Erik & Nygård, Jesper, 2006, In: Physical Review B. Condensed Matter and Materials Physics. 74, 23, p. 233304Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiac Arrhythmia - new considerations: The Cardiac Ion Channels
Jespersen, Thomas, 29 Feb 2012, Cardiac Arrhythmias - new considerations. Breijo-Marquez, F. R. (ed.). Croatia: InTech, p. 45-72 29 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif.
Jespersen, Thomas, Rasmussen, Hanne Borger, Grunnet, Morten, Jensen, H. S., Angelo, K., Dupuis, D. S., Vogel, L. K., Jorgensen, N. K., Klærke, Dan Arne & Olesen, Søren-Peter, 2004, In: Journal of Cell Science. 117, Pt 19, p. 4517-26 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The KCNQ1 potassium channel: from gene to physiological function.
Jespersen, Thomas, Grunnet, Morten & Olesen, Søren-Peter, 2005, In: Physiology. 20, p. 408-16 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Selective IK,ACh Inhibition by XAF-1407 in an Equine Model of Tachypacing-induced Persistent Atrial Fibrillation (AF)
Jespersen, Thomas, Fenner, Merle Friederike & Buhl, Rikke, 2019, In: Acta Physiologica. 227, S721, p. 96-96Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The KCNQ5 potassium channel from mouse: a broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes.
Jensen, H. S., Callø, Kirstine, Jespersen, Thomas, Jensen, B. S. & Olesen, Søren-Peter, 2005, In: Brain Research. 139, 1, p. 52-62 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common and rare variants in SCN10A modulate the risk of atrial fibrillation.
Jabbari, J., Olesen, Morten Steen Salling, Yuan, L., Nielsen, J. B., Liang, B., Macri, V., Christophersen, I. E., Nielsen, N., Sajadieh, Ahmad, Ellinor, P. T., Grunnet, Morten, Haunsø, Stig, Holst, A. G., Svendsen, Jesper Hastrup & Jespersen, Thomas, 2015, In: Circulation: Cardiovascular Genetics. 8, 1, p. 64-73 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of APD and Force by the Na+/Ca2+ Exchanger in Human-Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue
Ismaili, D., Gurr, K., Horvath, A., Yuan, L., Lemoine, M. D., Schulz, C., Sani, J., Petersen, J., Reichenspurner, H., Kirchhof, P., Jespersen, Thomas, Eschenhagen, T., Hansen, A., Koivumaeki, J. T. & Christ, T., 2022, In: Cells. 11, 15, 15 p., 2424.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia
Hyltén-Cavallius, L., Iepsen, E. W., Albrechtsen, Nicolai Jacob Wewer, Svendstrup, M., Lubberding, Anniek Frederike, Hartmann, Bolette, Jespersen, Thomas, Linneberg, Allan René, Christiansen, M., drb459, drb459, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K., Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Circulation. 135, 18, p. 1705-1719 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rat Models of Ventricular Fibrillation Following Acute Myocardial Infarction
Hundahl, L. A., Tfelt-Hansen, Jacob & Jespersen, Thomas, Nov 2017, In: Journal of Cardiovascular Pharmacology and Therapeutics. 22, 6, p. 514-528 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacological blockade of small conductance Ca-activated K channels by ICA reduces arrhythmic load in rats with acute myocardial infarction
Hundahl, L. A., Sattler, S. M., Skibsbye, L., Diness, J. G., Tfelt-Hansen, Jacob & Jespersen, Thomas, Jun 2017, In: Pflügers Archiv - European Journal of Physiology. 469, 5-6, p. 739-750 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functionally Selective AT(1) Receptor Activation Reduces Ischemia Reperfusion Injury
Hostrup, A., Christensen, G. L., Bentzen, Bo Hjorth, Liang, B., Aplin, M., Grunnet, Morten, Hansen, J. L. & Jespersen, Thomas, 30 Jul 2012, In: Cellular Physiology and Biochemistry. 30, 3, p. 642-652 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sick sinus syndrome, progressive cardiac conduction disease, atrial flutter and ventricular tachycardia caused by a novel SCN5A mutation
Holst, A. G., Liang, B., Jespersen, Thomas, Bundgård, Henning, Haunso, S., Svendsen, Jesper Hastrup & Tfelt-Hansen, J., 2010, In: Cardiology. 115, 4, p. 311-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease
Holst, A. G., Callø, Kirstine, Jespersen, Thomas, Cedergreen, P., Winkel, B. G., Jensen, H. K., Leren, T. P., Haunso, S., Svendsen, Jesper Hastrup & Tfelt-Hansen, J., 2009, In: Case Reports in Medicine. 2009, p. 963645Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does KCNE5 play a role in long QT syndrome?
Hofman-Bang, J., Jespersen, Thomas, Grunnet, Morten, Larsen, Lars Allan, Andersen, P. S., Kanters, Jørgen K., Kjeldsen, K. & Christiansen, M., 2004, In: Clinica Chimica Acta. 345, 1-2, p. 49-53 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electrophysiologic effects of the IK1 inhibitor PA-6 are modulated by extracellular potassium in isolated guinea pig hearts
Hoeker, G. S., Skarsfeldt, M. A., Jespersen, Thomas & Poelzing, S., Jan 2017, In: Physiological Reports. 5, 1, 10 p., e13120.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
O11 | In vitro and in vivo effects of dapagliflozin on adenosine diphosphate induced platelet aggregation response in Göttingen minipigs
Hinz, K., Lyhne, Mille Kronborg, Debes, Karina Poulsdóttir, Reimann, Maria Josefine, Flethøj, M., Bruun, Camilla Vibeke Sichlau, Ludvigsen, Trine Pagh, Kirchhoff, J., Jespersen, Thomas, Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2023, In: Journal of Veterinary Pharmacology and Therapeutics. 46, S1, p. 33 1 p., O11.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Implantable loop recorders for arrhythmia detection - a new promising diagnostic tool for longterm arrhythmia monitoring
Hesselkilde, E. Z., Carsten, H., Fenner, Merle Friederike, Jespersen, Thomas, T-felt, J., Sattler, Stefan M & Buhl, Rikke, 2019, In: Acta Physiologica. 227, S721, p. 93-93 35.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Longitudinal study of electrical, functional and structural remodelling in an equine model of atrial fibrillation
Hesselkilde, E. Z., Carstensen, Helena, Flethøj, M., Fenner, Merle Friederike, Kruse, D. D., Sattler, Stefan M, Tfelt-Hansen, Jacob, Pehrson, S., Braunstein, T. H., Carlson, J., Platonov, P. G., Jespersen, Thomas & Buhl, Rikke, 2019, In: BMC Cardiovascular Disorders. 19, 1, 12 p., 228.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of flecainide on atrial fibrillatory rate in a large animal model with induced atrial fibrillation
Hesselkilde, E. Z., Carstensen, Helena, Haugaard, M. M., Carlson, J., Pehrson, S., Jespersen, Thomas, Buhl, Rikke & Platonov, P. G., Dec 2017, In: B M C Cardiovascular Disorders. 17, 6 p., 289.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel approach for obtaining 12-lead electrocardiograms in horses
Hesselkilde, E. M., Isaksen, Jonas L., Petersen, B. V., Carstensen, Helena, Jespersen, Thomas, Pehrson, S., Kanters, Jørgen K. & Buhl, Rikke, 2021, In: Journal of Veterinary Internal Medicine. 35, 1, p. 521-531Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First catheter-based high-density endocardial 3D electroanatomical mapping of the right atrium in standing horses
Hesselkilde, E., Dr Linz, Dominik Karl, Saljic, Arnela, Carstensen, Helena, Kutieleh, R., Jespersen, Thomas, Sanders, P. & Buhl, Rikke, 2021, In: Equine Veterinary Journal. 53, 4, p. 186-193Research output: Contribution to journal › Journal article › Research › peer-review
- Published
3D-electroanatomical mapping of the left atrium and catheter-based pulmonary vein isolation in pigs: A practical guide
Hertel, Julie Norup, Jerltorp, K., Hansen, Malthe Emil Høtbjerg, Isaksen, Jonas L., Sattler, Stefan M, Linz, Benedikt Maximilian, Chaldoupi, S. M., Jespersen, Thomas, Saljic, Arnela, Gang, Uffe Jakob Ortved, Manninger, M. & Dr Linz, Dominik Karl, 2023, In: Frontiers in Cardiovascular Medicine. 10, 8 p., 1139364.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhanced Ca2+-Dependent SK-Channel Gating and Membrane Trafficking in Human Atrial Fibrillation
Heijman, J., Zhou, X., Morotti, S., Molina, C. E., Abu-Taha, I. H., Tekook, M., Jespersen, Thomas, Zhang, Y., Dobrev, S., Milting, H., Gummert, J., Karck, M., Kamler, M., El-Armouche, A., Saljic, Arnela, Grandi, E., Nattel, S. & Dobrev, D., 2023, In: Circulation Research. 132, 9, p. E116-E133Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of CAV3 in long-QT syndrome: clinical and functional assessment of a caveolin-3/Kv11.1 double heterozygote versus caveolin-3 single heterozygote
Hedley, P. L., Kanters, Jørgen K., Dembic, M., Jespersen, Thomas, Skibsbye, L., Aidt, F. H., Eschen, O., Graff, C., Behr, E. R., Schlamowitz, S., Corfield, V., McKenna, W. J. & Christiansen, M., Oct 2013, In: Circulation: Cardiovascular Genetics. 6, 5, p. 452-61 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses
Haugaard, M. M., Pehrson, S., Carstensen, Helena, Madsen, M. F., Hesselkilde, E. Z., Præstegaard, K. F., Diness, J. G., Grunnet, M., Jespersen, Thomas & Buhl, Rikke, 2015, In: Journal of Veterinary Internal Medicine. 29, 1, p. 339-347 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses
Haugaard, M. M., Hesselkilde, E. Z., Pehrson, S. M., Carstensen, Helena, Madsen, M. F., Præstegaard, K. F., Sørensen, U. S., Diness, J. G., Grunnet, M., Buhl, Rikke & Jespersen, Thomas, Apr 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 4, p. 825-835 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Atrieflimmer og elektrofysiologi hos heste
Haugaard, M. M., Buhl, Rikke & Jespersen, Thomas, 2011, In: Dansk Veterinaertidsskrift. 12, p. 28-31 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
hKCNE4 inhibits the hKCNQ1 potassium current without affecting the activation kinetics.
Grunnet, Morten, Olesen, Søren-Peter, Klærke, Dan Arne & Jespersen, Thomas, 2005, In: Biochemical and Biophysical Research Communications. 328, 4, p. 1146-53 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.
Grunnet, Morten, Rasmussen, H. B., Hay-Schmidt, Anders, Rosenstierne, M., Klærke, Dan Arne, Olesen, Søren-Peter & Jespersen, Thomas, 2003, In: Biophysical Journal. 85, 3, p. 1525-37 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of two new dominant ClC-1 channel mutations associated with myotonia.
Grunnet, Morten, Jespersen, Thomas, Colding-Jørgensen, E., Schwartz, M., Klærke, Dan Arne, Vissing, John, Olesen, Søren-Peter & Dunø, M., 2003, In: Muscle & Nerve. 28, 6, p. 722-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recruitment of motor neuronal persistent inward currents shapes withdrawal reflexes in the frog
Grunnet, Morten, Jespersen, Thomas & Perrier, Jean-Francois Marie, 2004, In: Journal of Neuroscience Research. 78, p. 845-854Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KCNE4 is an inhibitory subunit to the KCNQ1 channel.
Grunnet, Morten, Jespersen, Thomas, Rasmussen, Hanne Borger, Ljungstrøm, T., Jorgensen, N. K., Olesen, Søren-Peter & Klærke, Dan Arne, 2002, In: Journal of Physiology. 542, Pt 1, p. 119-30 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KCNQ1 channels sense small changes in cell volume.
Grunnet, Morten, Jespersen, Thomas, MacAulay, Nanna, Jørgensen, N. K., Schmitt, Nicole, Pongs, O., Olesen, Søren-Peter & Klærke, Dan Arne, 2003, In: Journal of Physiology. 549, Pt 2, p. 419-27 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
5-HT1A receptors modulate small-conductance Ca2+-activated K+ channels.
Grunnet, Morten, Jespersen, Thomas & Perrier, J., 2004, In: Journal of Neuroscience Research. 78, 6, p. 845-54 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacological modulation of SK3 channels
Grunnet, Morten, Jespersen, Thomas, Angelo, K., Frøkjær-Jensen, Christian, Klærke, Dan Arne, Olesen, Poul & Jensen, B. S., 1 Jun 2001, In: Neuropharmacology. 40, 7, p. 879-887 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stability of Circulating Blood-Based MicroRNAs - Pre-Analytic Methodological Considerations
Glinge, C., Clauss, S., Boddum, K., Jabbari, R., Jabbari, J., Risgaard, B., Tomsits, P., Hildebrand, B., Kääb, S., Wakili, R., Jespersen, Thomas & Tfelt-Hansen, Jacob, 2017, In: PLOS ONE. 12, 2, 16 p., e0167969.Research output: Contribution to journal › Journal article › Research › peer-review
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Gut microbiota, dysbiosis and atrial fibrillation. Arrhythmogenic mechanisms and potential clinical implications
Gawalko, M., Agbaedeng, T. A., Saljic, Arnela, Mueller, D. N., Wilck, N., Schnabel, R., Penders, J., Rienstra, M., van Gelder, I., Jespersen, Thomas, Schotten, U., Crijns, H. J. G. M., Kalman, J. M., Sanders, P., Nattel, S., Dobrev, D. & Dr Linz, Dominik Karl, 2022, In: Cardiovascular Research. 118, 11, p. 2415–2427Research output: Contribution to journal › Review › Research › peer-review
- Published
The gut microbial-derived metabolite trimethylamine N-oxide: A missing link between lifestyle-components and atrial fibrillation?
Gawalko, M., Jespersen, Thomas, Dobrev, D. & Dr Linz, Dominik Karl, 2020, In: IJC Heart and Vasculature. 29, 3 p., 100581.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Adiposity-associated atrial fibrillation: molecular determinants, mechanisms, and clinical significance
Gawalko, M., Saljic, Arnela, Li, N., Abu-Taha, I., Jespersen, Thomas, Dr Linz, Dominik Karl, Nattel, S., Heijman, J., Fender, A. & Dobrev, D., 2023, In: Cardiovascular Research. 119, 3, p. 614–630 17 p.Research output: Contribution to journal › Review › Research › peer-review
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Effective termination of atrial fibrillation by SK channel inhibition is associated with a sudden organization of fibrillatory conduction
Gatta, G., Sobota, V., Citerni, C., Diness, Jonas Goldin, Sørensen, U. S., Jespersen, Thomas, Bentzen, Bo Hjorth, Zeemering, S., Kuiper, M., Verheule, S., Schotten, U. & Van Hunnik, A., 2021, In: Europace. 23, 11, p. 1847-1859 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of Small-Conductance Calcium-Activated Potassium Current (IK,Ca) Leads to Differential Atrial Electrophysiological Effects in a Horse Model of Persistent Atrial Fibrillation
Fenner, Merle Friederike, Gatta, G., Sattler, Stefan M, Kuiper, M., Hesselkilde, E. M., Adler, Ditte Marie Top, Smerup, Morten Holdgaard, Schotten, U., Sørensen, U., Diness, J. G., Jespersen, Thomas, Verheule, S., Van Hunnik, A. & Buhl, Rikke, 2021, In: Frontiers in Physiology. 12, 614483.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Selective IK,ACh Inhibition by XAF-1407 in an Equine Model of Tachypacing-induced Persistent Atrial Fibrillation (AF)
Fenner, Merle Friederike, Carstensen, Helena, Nissen, Sarah Dalgas, Hesselkilde, E. Z., Lunddahl, C., Jensen, M. A. H., Loft-Andersen, A. V., Sattler, Stefan M, Platonov, P. G., El-Haou, S., Jackson, C., Tang, R., Kirby, R., Ford, J. W., Schotten, U., Milnes, J. T., Sørensen, U. S., Jespersen, Thomas & Buhl, Rikke, 2020, In: British Journal of Pharmacology. 177, 16, p. 3778-3794Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Left atrial functional measurements’ utility in predicting long-term risk of atrial fibrillation after isolated CABG
Dyhr, M. R., Olsen, F. J., Lindberg, S., Modin, D., Fritz-Hansen, T., Pedersen, S., Iversen, A., Galatius, S., Jespersen, Thomas, Møgelvang, R. & Biering-Sørensen, Tor, 2023, In: Echocardiography. 40, 7, p. 695-702 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Activation of KCNQ5 channels stably expressed in HEK293 cells by BMS-204352.
Dupuis, D. S., Schrøder, R. L., Jespersen, Thomas, Christensen, J. K., Christophersen, P., Jensen, B. S. & Olesen, Søren-Peter, 2002, In: European Journal of Pharmacology. 437, 3, p. 129-37 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Difference in allelic expression of the CLCN1 gene and the possible influence on the myotonia congenita phenotype.
Dunø, M., Colding-Jørgensen, E., Grunnet, Morten, Jespersen, Thomas, Vissing, John & Schwartz, M., 2004, In: European Journal of Human Genetics. 12, 9, p. 738-43 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional testing of a bicistronic retroviral vector for intracellular peptide production
Duch, M. R., Tolstrup, A., Dalum, I., Jespersen, Thomas, Mouritsen, S. & Pedersen, F. S., 1 Jun 1999, In: BioTechniques. 26, 6, p. 1032-4, 1036Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transgene stability for three replication-competent murine leukemia virus vectors
Duch, M. R., Carrasco, M. L., Jespersen, T., Hansen, B. D., Pedersen, F. S. & Jespersen, Thomas, 31 Mar 2004, In: Gene. 329, p. 61-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An RNA secondary structure bias for non-homologous reverse transcriptase-mediated deletions in vivo
Duch, M. R., Carrasco, M. L., Jespersen, T., Aagaard, L., Pedersen, F. S. & Jespersen, Thomas, 1 Jan 2004, In: Nucleic Acids Symposium Series. 32, 6, p. 2039-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations between thyroid-stimulating hormone, blood pressure and adiponectin are attenuated in children and adolescents with overweight or obesity
Drivsholm, A., Lund, Morten Asp Vonsild, Hedley, P. L., Jespersen, Thomas, Christiansen, M., Hansen, Torben & Holm, Jens-Christian, 2019, In: Journal of Pediatric Endocrinology and Metabolism. 32, 12, p. 1351-1358Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8117
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Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
349
downloads
Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
329
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Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia
Research output: Contribution to journal › Journal article › Research › peer-review
Published