Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
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Incretin Effect and Glucagon Responses to Oral and Intravenous Glucose in Patients with Maturity Onset Diabetes of the Young - Type 2 and Type 3
Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 27 Mar 2014, In: Diabetes. 63, 8, p. 2838-44 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The incretin effect in patients with maturity onset diabetes of the young
Ostoft, S. H., Bagger, J. I., Hansen, T., Pedersen, O., Holst, Jens Juul, Knop, Filip Krag & Vilsboll, T., 2012, In: Diabetologia. 55, p. S144-S144Research output: Contribution to journal › Journal article › Research › peer-review
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GLP-1 does not not acutely affect insulin sensitivity in healthy man
Orskov, L., Holst, Jens Juul, Møller, J., Ørskov, Cathrine, Møller, N., Alberti, K. G. & Schmitz, O., Oct 1996, In: Diabetologia. 39, 10, p. 1227-32 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans
Ørskov, Cathrine, Rabenhøj, L., Wettergren, A., Kofod, H. & Holst, Jens Juul, Apr 1994, In: Diabetes. 43, 4, p. 535-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting state and after oral glucose and intravenous arginine
Ørskov, Cathrine, Jeppesen, J., Madsbad, Sten & Holst, Jens Juul, Feb 1991, In: The Journal of Clinical Investigation. 87, 2, p. 415-23 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of truncated glucagon-like peptide-1 [proglucagon-(78-107) amide] on endocrine secretion from pig pancreas, antrum, and nonantral stomach
Ørskov, Cathrine, Holst, Jens Juul & Nielsen, O. V., Oct 1988, In: Molecular Endocrinology. 123, 4, p. 2009-13 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I
Ørskov, Cathrine, Poulsen, Steen Seier, Møller, Morten & Holst, Jens Juul, Jun 1996, In: Diabetes. 45, 6, p. 832-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Carboxypeptidase-B-like processing of the C-terminus of glucagon-like peptide-2 in pig and human small intestine
Ørskov, Cathrine, Buhl, T., Rabenhøj, L., Kofod, H. & Holst, Jens Juul, 24 Apr 1989, In: F E B S Letters. 247, 2, p. 193-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Complete sequences of glucagon-like peptide-1 from human and pig small intestine
Ørskov, Cathrine, Bersani, M., Johnsen, A. H., Højrup, P. & Holst, Jens Juul, 5 Aug 1989, In: The Journal of Biological Chemistry. 264, 22, p. 12826-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biological effects and metabolic rates of glucagonlike peptide-1 7-36 amide and glucagonlike peptide-1 7-37 in healthy subjects are indistinguishable
Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, May 1993, In: Diabetes. 42, 5, p. 658-61 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Secretion of the incretin hormones glucagon-like peptide-1 and gastric inhibitory polypeptide correlates with insulin secretion in normal man throughout the day
Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, Jul 1996, In: Scandinavian Journal of Gastroenterology. 31, 7, p. 665-70 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Radio-immunoassays for glucagon-like peptides 1 and 2 (GLP-1 and GLP-2)
Ørskov, Cathrine & Holst, Jens Juul, Apr 1987, In: Scandinavian Journal of Clinical and Laboratory Investigation. Supplement. 47, 2, p. 165-74 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of oleic acid and endogenous bile on the duodenal secretion of somatostatin in man
Olsen, O., Holst, Jens Juul & Schaffalitzky de Muckadell, O. B., 1992, In: Dig. Diseases and Sciences. 37(7), p. 1025-1028Research output: Contribution to journal › Journal article › Research › peer-review
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Kirurgisk behandling af type 2-diabetes
Olesen, S. C., Hansen, D. L., Almdal, Thomas Peter, Bendtsen, Flemming, Nordgaard, I., Hvolris, L. E., Holst, Jens Juul, Naver, L. & Madsbad, Sten, 2009, In: Ugeskrift for læger. 171, 8, p. 615-7 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Importance of colonic fermentation in short bowel patients. Small intestinal malabsorption of easily digestible carbohydrate
Olesen, M., Gudmand-Høyer, E., Holst, Jens Juul & Jørgensen, S., 1999, In: Dig. Dis. Sci.. 44, p. 1914-1923Research output: Contribution to journal › Journal article › Research › peer-review
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Administration of a dipeptidyl peptidase IV inhibitor enhances the intestinal adaptation in a mouse model of short bowel syndrome
Okawada, M., Holst, Jens Juul & Teitelbaum, D. H., Aug 2011, In: Surgery. 150, 2, p. 217-223 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial hypoglycaemia after Roux-en-Y gastric bypass and the effects of acarbose, sitagliptin, verapamil, liraglutide and pasireotide
Ohrstrom, C. C., Worm, Dorte, Hojager, A., Andersen, D., Holst, Jens Juul, Kielgast, U. L. & Hansen, D. L., 2019, In: Diabetes, Obesity and Metabolism. 21, 9, p. 2142-2151Research output: Contribution to journal › Journal article › Research › peer-review
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A Low Dose of Pasireotide Prevents Hypoglycemia in Roux-en-Y Gastric Bypass-Operated Individuals
Ohrstrom, C. C., Hansen, D. L., Kielgast, U. L., Hartmann, Bolette, Holst, Jens Juul & Worm, Dorte, 2020, In: Obesity Surgery. 30, p. 1605-1610 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Are early dumping and postprandial hypoglycaemia after Roux-en-Y gastric bypass related events? [Meeting Abstract}
Ohrstrom, C. C., Hansen, D. L., Holst, Jens Juul, Kielgast, U. L. & Worm, Dorte, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S48-S48 92.Research output: Contribution to journal › Conference abstract in journal › Research
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Pancreatic and Intestinal Function Post Roux-en-Y Gastric Bypass Surgery for Obesity
O'Keefe, S. J. D., Rakitt, T., Ou, J., El Hajj, I. I., Blaney, E., Vipperla, K., Holst, Jens Juul & Rehlfeld, J., 3 Aug 2017, In: Clinical and Translational Gastroenterology. 8, 11 p., e112.Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment of adult short bowel syndrome patients with teduglutide
Nørholk, L. M., Holst, Jens Juul & Jeppesen, Palle Bekker, 2012, In: Expert Opinion on Pharmacotherapy. 13, 2, p. 235-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Congenital Glucagon-like peptide-1 deficiency in the pathogenesis of protracted diarrhea in Mitchell Riley syndrome
Nóbrega, S., Monteiro, M. P., Pereira-da-Silva, L., Pereira, S. S., Hartmann, Bolette, Holst, Jens Juul, Barbosa Silva, R. & Cordeiro-Ferreira, G., 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 4, p. 1084-1090Research output: Contribution to journal › Journal article › Research › peer-review
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Prandial subcutaneous injections of glucagon-like peptide-1 cause weight loss in obese human subjects
Näslund, E., King, N., Mansten, S., Adner, N., Holst, Jens Juul, Gutniak, M. & Hellström, P. M., Mar 2004, In: The British Journal of Nutrition. 91, 3, p. 439-46 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Energy intake and appetite is suppressed by glucagon-like peptide-1 (GLP-1) in obese men
Näslund, E., Barkeling, B., King, N., Gutniak, M. K., Blundell, J. E., Holst, Jens Juul, Rössner, S. & Hellström, P. M., 1999, In: International Journal of Obesity. 23, p. 304-311Research output: Contribution to journal › Journal article › Research › peer-review
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Prandial subcutaneous injections of glucagons-like peptide- 1 cause weight loss in obese human subjects
Näslund, E., King, N., Mansten, S., Adner, N., Holst, Jens Juul, Gutniak, M. & Hellström, P., 2004, In: Br.J.Nutr.. 91, p. 439-446Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 slows solid gastric emptying and inhibits insulin, glucagon and peptide YY release in humans
Näslund, E., Bogefors, J., Skogar, S., Grybäck, P., Jacobsen, H. L., Holst, Jens Juul & Helström, P. M., 1999, In: Am. J. Physiol.. 277, p. 910-916Research output: Contribution to journal › Journal article › Research › peer-review
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Gastrointestinal hormones and gastric emptying 20 years after jejunoileal bypass for massive obesity.
Näslund, E., Grybäck, P., Hellström, P. M., Jacobsson, H., Holst, Jens Juul, Theodorsson, E. & Backmann, L., 1997, In: International Journal of Obesity. 21, p. 387-392Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease.
Nyström, T., Gutniak, M. K., Zhang, Q., Zhang, F., Holst, Jens Juul, Ahrén, B. & Sjöholm, A., 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 6, p. E1209-15Research output: Contribution to journal › Journal article › Research › peer-review
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Suboptimal Weight Loss 13 Years After Roux-en-Y Gastric Bypass Is Associated with Blunted Appetite Response
Nymo, S., Lundanes, J., Eriksen, K., Aukan, M., Rehfeld, Jens Frederik, Holst, Jens Juul, Johnsen, G., Græslie, H., Kulseng, B., Sandvik, J. & Martins, C., 2024, In: Obesity Surgery. 34, 2, p. 592-601Research output: Contribution to journal › Journal article › Research › peer-review
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Hour profiles of insulin, subtrates and gut incretin hormones: Early defects in glucose tolerant offspring of type II (non-insulin dependent) diabetic paitents
Nyholm, B., Walker, M. J. C., Gravholdt, C. H., Alberti, K. G. M. M., Holst, Jens Juul & Schmitz, O., 1999, In: Diabetologia. 42, p. 1314-1323Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease
Niu, Lili, Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Treit, P. V., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Müller, T. D., Tschöp, M. H., Hofmann, S. M. & Mann, Matthias, 2019, In: Molecular Systems Biology. 15, 16 p., e8793.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma proteome profiling discovers potential biomarkers of non-alcoholic fatty liver disease
Niu, Lili, Gupta, R., Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Mueller, T. D., Tschoep, M. H., Hofmann, S. M. & Mann, Matthias, Aug 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S71 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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A Pilot Study Showing Acute Inhibitory Effect of GLP-1 on the Bone Resorption Marker CTX in Humans
Nissen, A., Marstrand, S., Skov-Jeppesen, Kirsa, Bremholm, L., Hornum, Mads, Andersen, U. B., Holst, Jens Juul, Rosenkilde, M. M. & Hartmann, Bolette, 2019, In: JBMR Plus. 3, 10, 6 p., e10209.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucose-dependent insulinotropic polypeptide inhibits bone resorption in humans
Nissen, A., Christensen, Mikkel Bring, Knop, Filip Krag, Vilsbøll, T., Holst, Jens Juul & Hartmann, Bolette, Nov 2014, In: The Journal of clinical endocrinology and metabolism. 99, 11, p. E2325-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glycemia and insulinemia in healthy subjects after lactose-equivalent meals of milk and other food proteins: the role of plasma amino acids and incretins
Nilsson, M., Stenberg, M., Frid, A. H., Holst, Jens Juul & Björck, I. M. E., Nov 2004, In: Uden navn. 80, 5, p. 1246-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of DPP-4-protected GLP-1 (7-36) on coronary microvascular function in obese adults
Nilsson, M., Bové, K. B., Suhrs, E., Hermann, T., Madsbad, Sten, Holst, Jens Juul, Prescott, Eva & Zander, M., Mar 2019, In: IJC Heart and Vasculature. 22, p. 139-144Research output: Contribution to journal › Journal article › Research › peer-review
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Metabolic effects of amino acid mixtures and whey protein in healthy subjects: studies using glucose-equivalent drinks
Nilsson, M., Holst, Jens Juul & Bjorck, I. M. E., 2007, In: American Journal of Clinical Nutrition. 85, 4, p. 996-1004 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of DPP-4 protected GLP-1 (7-36) on coronary microcirculation in obese adults
Nilsson, M., Bove, K., Suhrs, E., Hermann, T., Madsbad, Sten, Holst, Jens Juul, Prescott, Eva & Zander, M., 2018, In: Diabetologia. 61, S1, p. S354-S355 729.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Glycemia and insulinemia in healthy subjects after lactose equivalent meals of milk and other food proteins: on the role of plasma amino acids and incretins
Nilsson, M., Stenberg, M., Frid, A. H., Holst, Jens Juul & Björck, I., 2004, In: Am. J. Clin. Nutr.. 80, p. 1246-1253Research output: Contribution to journal › Journal article › Research › peer-review
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A cereal-based evening meal rich in indigestible carbohydrates increases plasma butyrate the next morning
Nilsson, A. C., Östman, E. M., Knudsen, K. E. B., Holst, Jens Juul & Björck, I. M. E., 1 Nov 2010, In: Journal of Nutrition. 140, 11, p. 1932-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast
Nilsson, A. C., Ostman, E. M., Holst, Jens Juul & Björck, I. M. E., Apr 2008, In: Journal of Nutrition. 138, 4, p. 732-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast
Nilsson, A. C., Ostman, E. M., Holst, Jens Juul & Bjorck, I. M., 2008, In: Journal of Nutrition. 138, 4, p. 732-739 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Onset of small intestinal atrophy is associated with reduced intestinal blood flow in TPN-fed neonatal piglets
Niinikoski, H., Stoll, B., Guan, X., Kansagra, K., Lambert, B. D., Stephens, J., Hartmann, Bolette, Holst, Jens Juul & Burrin, D. G., Jun 2004, In: Journal of Nutrition. 134, 6, p. 1467-74 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Onset of small intestinal atrophy is associated with reduced intestinal blod flow in TNP-fed neonatal piglets
Niinikoski, H., Stoll, B., Guam, X., Kansagra, K., Lambert, B., Hartmann, B., Holst, Jens Juul & Burrin, D. G., 2004, In: Journal of Nutrition. 134, p. 1467-1474Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of GLP-2 treatment and antibiotics on gut structure and function during pig weanling diarrhea
Nielsen, T. T., Sangild, Per Torp, Elnif, J., Sorensen, K., Leser, T., Holst, Jens Juul, Hartmann, B., Jensen, B. B. & Hedemann, M. S., 2003, Ikke angivet. R.O. Ball (ed.). 2 ed. University of Alberta Press, p. 161-163 3 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
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Functional and immunohistochemical evaluation of porcine neonatal islet-like cell clusters.
Nielsen, T. B., Yderstraede, K. B., Schrøder, H. D., Holst, Jens Juul, Brusgaard, K. & Beck-Nielsen, H., 2003, In: Cell Transplantation. 12, 1, p. 13-25 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of Pancreatic α-Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) In Vitro
Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of Pancreatic Alpha Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) in vitro.
Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p., 27479530 .Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of tumor necrosis factor-alpha infusion on the incretin effect in healthy volunteers
Nielsen, S. T., Lehrskov-Schmidt, L., Krogh-Madsen, R., Solomon, T., Lehrskov-Schmidt, L., Holst, Jens Juul & Møller, K., 31 Jul 2013, In: Diabetes - Metabolism: Research and Reviews (Online). 29, 8, p. 655-663 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chenodeoxycholic acid stimulates glucagon-like peptide-1 secretion in patients after Roux-en-Y gastric bypass
Nielsen, S., Svane, M. S., Kuhre, Rune Ehrenreich, Clausen, T. R., Kristiansen, V. B., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Bojsen-Moller, K. N., Feb 2017, In: Physiological Reports. 5, 3, 11 p., e13140.Research output: Contribution to journal › Journal article › Research › peer-review
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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