Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- 1997
- Published
Enteroglucagon
Holst, Jens Juul, 1997, In: Annual Reviews of Physiology. 59, p. 257-272Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Holder GLP-1 som nyt terapeutisk princip i diabetesbehandlingen hvad det lovede?
Holst, Jens Juul, 1997, In: Tidsskrift for Diabetesbehandling. 2(7), p. 16-22Research output: Contribution to journal › Journal article › Research
- Published
Non-insulin-dependent diabetes mellitus - new drugs?
Holst, Jens Juul, 1997, In: Drug Discovery Today. 2, p. 128-129Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Posttranslational processing of proglucagon and postsecretory fate of proglucagon products.
Holst, Jens Juul, Ørskov, C., Hartmann, B. & Deacon, Carolyn F., 1997, The Insulinotropic Gut Hormone Glucagon-like Peptide-1.. Basel: Karger, p. 24-48Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
The pathogenesis of non-insulin dependent diabetes mellitus involves a defective expression of the GIP receptor.
Holst, Jens Juul, Gromada, J. L. & Nauck, M. A., 1997, In: Diabetologia. 40, p. 984-986Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem
Larsen, P. J., Tang-Christensen, M., Holst, Jens Juul & Ørskov, Cathrine, 1997, In: Neuroscience. Vol. 77, No. 1, p. 257-270Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 (GLP-17-36amide) reduces hepatic glucose production indirectly through changes in insulin and glucagon secretion.
Larsson, H., Holst, Jens Juul & Ahrén, B., 1997, In: Acta Phys. Scand.. 160, p. 413-422Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered postprandial motility in chronic pancreatitis: role of malabsorption.
Layer, P., v.d. Ohe, M. R., Grandt, D., Holst, Jens Juul, Jansen, J. B. M. J., Holtmann, G., Keller, J. & Goebell, H., 1997, In: Today in Medicine. Gastroenterology. 112, p. 1624-1634Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans
Nauck, M. A., Niedereichholz, U., Ettler, R., Holst, Jens Juul, Ørskov, Cathrine, Ritzel, R. & Schmiegel, W. H., Nov 1997, In: American Journal of Physiology (Consolidated). 273, 5 Pt 1, p. E981-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of GLP-1 on gastric and pancreatic exocrine secretion and on gastrointestinal motility.
Nauck, M. A., Schepp, W., Holst, Jens Juul & Schmiegel, W. H., 1997, The Insulintropic Gut Hormone Glucagon-Like Peptide-1, Front Diabetes vol. 13. Basel: Karger, p. 194-206Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Glucagon-like peptide-1 (GLP-1) as a new therapeutic approach for type-2 diabetes.
Nauck, M. A., Holst, Jens Juul, Willms, B. & Schmiegel, W., 1997, In: Exp. Clin. Endocrinol. Diabetes. 105, p. 187-195Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastrointestinal hormones and gastric emptying 20 years after jejunoileal bypass for massive obesity.
Näslund, E., Grybäck, P., Hellström, P. M., Jacobsson, H., Holst, Jens Juul, Theodorsson, E. & Backmann, L., 1997, In: International Journal of Obesity. 21, p. 387-392Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose absorption and the release of insulin, gastric inhibitory polypeptide, and glucagon-like peptide-1 in patients after total colectomy.
Palnæs Hansen, C., Andreassen, J. & Holst, Jens Juul, 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 473-477Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The release of gastric inhibitory peptide, glucagon-like peptide-1, and insulin after oral glucose test in colectomized subjects.
Palnæs Hansen, C., Andreassen, J. & Holst, Jens Juul, 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 473-477Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A double-blind placebo-controlled study on the effects of omeprazole on gut hormone secretion and gastric emptying rate.
Rasmussen, L., Qvist, N., Øster-Jørgensen, E., Rehfeld, J. F., Holst, Jens Juul & Pedersen, S. A., 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 900-905Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Einfluss von subkutanem GLP-1 auf die frühe und langsame Phase der Insulin-sekretion nach intravenöser Glukosebelastung bei gesunden Probanden.
Ritzelt, R., Ørskov, C., Holst, Jens Juul, Schmiegel, W. & Nauck, M. A., 1997, In: Diabetes und Stoffwechsel. 6, p. 64-69.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bombesin inhibits histamine release from the rat oxyntic mucosa by a somatostatin-dependent mechanism.
Sandvik, A. K., Brenna, E., Sundan, A., Holst, Jens Juul & Waldum, H. L., 1997, In: Scandinavian Journal of Gastroenterology. 30, p. 427-432Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating GRP and gastrin in fetal lambs in response to luminal infusion of fluids
Sangild, Per Torp, Hilsted, L., Bjørnskov-Bartholdy, L., Holst, Jens Juul & Trahair, J. F., 1997.Research output: Contribution to conference › Paper › Research
- Published
Use of antagonists to define tachykininergic control of intestinal motility in pigs.
Schmidt, P. & Holst, Jens Juul, 1997, In: Peptides. 18, p. 373-379Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of glucagon-like peptide-1 (7-36amide) on whole body protein metabolism in healthy man.
Shalev, A., Holst, Jens Juul & Keller, U., 1997, In: European Journal of Clinical Investigation. 27, p. 10-16.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short-term insulin treatment prevents the diabetogenic action of streptozotocin in rats
Thulesen, J., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Jan 1997, In: Endocrinology. 138, 1, p. 62-68 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short term insulin treatment prevents the diabetogenic action of streptozotocin in rats
Thulesen, J., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 1997, In: Endokrinologiya. Vol. 138, No. 1, p. 62-68Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PACAP 1-38 as neurotransmitter in the pig pancreas: PACAP-receptor activation revealed by the antagonist PACAP 6-38.
Tornøe, K., Hannibal, J., Fahrenkrug, J. & Holst, Jens Juul, 1997, In: Am. J. Physiol.. 273, p. G436-G446Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 7-36amide and peptide YY have additive inhibitory effects on gastric acid secretion in man.
Wettergren, A., Maina, P., Boesby, S. & Holst, Jens Juul, 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 552-555Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The inhibitory effect of glucagon-like peptide-1 (GLP-1) 7-36 amide on gastric acid secretion in humans depends on an intact vagal innervation.
Wettergren, A., Wøjdemann, M., Meisner, S., Stadil, F. & Holst, Jens Juul, 1997, In: Gut. 40, p. 597-601Research output: Contribution to journal › Journal article › Research › peer-review
- 1996
- Published
Impaired insulin-stimulated nonoxidative glucose metabolism in pancreas-kidney transplant recipients: dose-response effects of insulin on glucose turnover
Christiansen, E., drb459, drb459, Tibell, A., Hother-Nielsen, O., Holst, Jens Juul, Pedersen, O. & Madsbad, Sten, 1996, In: Diabetes. 45, 9, p. 1267-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients
Creutzfeldt, W. O., Kleine, N., Willms, B., Ørskov, Cathrine, Holst, Jens Juul & Nauck, M. A., Jun 1996, In: Diabetes Care. Supplement. 19, 6, p. 580-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the effects of glucagon-like peptide-1 on blood glucose regulation in normal and diabetic subjects
Holst, Jens Juul, Toft-Nielsen, M. B., Ørskov, Cathrine, Nauck, M. & Willms, B., 26 Dec 1996, In: Annals of the New York Academy of Sciences. 805, p. 729-36 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM
Nauck, M. A., Wollschläger, D., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Willms, B., Dec 1996, In: Diabetologia. 39, 12, p. 1546-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Release of glucagon-like peptide 1 (GLP-1 [7-36 amide]), gastric inhibitory polypeptide (GIP) and insulin in response to oral glucose after upper and lower intestinal resections
Nauck, M. A., Siemsglüss, J., Ørskov, Cathrine & Holst, Jens Juul, Mar 1996, In: Zeitschrift fur Gastroenterologie. 34, 3, p. 159-66 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I
Ørskov, Cathrine, Poulsen, Steen Seier, Møller, Morten & Holst, Jens Juul, Jun 1996, In: Diabetes. 45, 6, p. 832-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of the incretin hormones glucagon-like peptide-1 and gastric inhibitory polypeptide correlates with insulin secretion in normal man throughout the day
Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, Jul 1996, In: Scandinavian Journal of Gastroenterology. 31, 7, p. 665-70 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 does not not acutely affect insulin sensitivity in healthy man
Orskov, L., Holst, Jens Juul, Møller, J., Ørskov, Cathrine, Møller, N., Alberti, K. G. & Schmitz, O., Oct 1996, In: Diabetologia. 39, 10, p. 1227-32 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Positive effects on plasma glucose & appetite by industrial modification of starch
Raben, A., Andersen, K., Karberg, M. A., Holst, Jens Juul & Astrup, A., 1996. 1 p.Research output: Contribution to conference › Poster › Research
- Published
Gastrin release in the fetal lamb in response to luminal infusion of amniotic fluid, milk or GRP
Sangild, Per Torp, Hilsted, L., Bjørnskov-Bartholdy, L., Holst, Jens Juul & Trahair, J. F., 1996. 1 p.Research output: Contribution to conference › Paper › Research
- Published
Tachykinins mediate vagal inhibition of gastrin secretion in pigs
Schmidt, P., Poulsen, Steen Seier, Hilsted, Linda, Rasmussen, T. N. & Holst, Jens Juul, Oct 1996, In: Gastroenterology. 111, 4, p. 925-35 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1
Serup, P., Jensen, J., Andersen, F. G., Jørgensen, Mette Christine, Blume, N., Holst, Jens Juul & Madsen, O. D., 20 Aug 1996, In: Proceedings of the National Academy of Sciences of the United States of America. 93, 17, p. 9015-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients
Willms, B., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Nauck, M. A., Jan 1996, In: Endocrinology. 81, 1, p. 327-32 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
- Published
Potent inhibitory effects of transplantable rat glucagonomas and insulinomas on the respective endogenous islet cells are associated with pancreatic apoptosis.
Blume, N., Skouv, J., Larsson, L., Holst, Jens Juul & Madsen, O. D., 1995, In: J. Clin. Invest.. 96, p. 2227-2235Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of glucagon in the maintenance of euglycemia in the fed and the fasted state. Monoclonal antibody treatment as a tool in glucagon physiology in rats.
Brand, C. L., Jørgensen, P. N., Svendsen, I., Kristensen, J. S., Knigge, U., Warberg, J. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. E469-E477Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of endogenous hypergastrinemia on gastrin receptor expressing human colon carcinoma transplanted to athymic rats.
Chu, M., Franzén, L., Rehfeld, J. F., Holst, Jens Juul & Borch, K., 1995, In: Today in Medicine. Gastroenterology. 109, p. 1415-1420Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Both subcutaneously and intravenously administered glucagon-like peptide-1 are rapidly degraded from the amino terminus in type II diabetic patients and in healthy subjects.
Deacon, Carolyn F., Nauck, M. A., Nielsen, M. T., Pridal, L. & Holst, Jens Juul, 1995, In: Diabetes. 44, p. 1126-1131Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Degradation of glucagon-like peptide-1 in vitro yields an N-terminally truncated peptide which is a major endogenous metabolite in vivo.
Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, p. 952-957Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human colon produces fully processed glucagon-like peptide-1 (7-36 amide).
Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: FEBS Letters. 372, p. 269-272.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sympathoadrenal regulation of adrenocortical steroidogenesis
Ehrhart-Bornstein, M., Bornstein, S. R., Gonzalez-Hernandez, J., Holst, Jens Juul, Watermann, M. R. & Scherbaum, W. A., 1995, In: Endocrine Research. 21, p. 13-24Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiological augmentation of amino acid-induced insulin secretion by GIP and GLP-I but not by CCK-8
Fieseler, P., Bridenbaugh, S., Nustede, R., Martell, J., Nauck, M. A., Ørskov, Cathrine & Holst, Jens Juul, 1995, In: Am. J. Physiol.. Vol 268, p. E949-E955Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus.
Hannibal, J., Mikkelsen, J. D., Clausen, H., Holst, Jens Juul, Wulff, B. S. & Fahrenkrug, J., 1995, In: Regulatory Peptides. 55, p. 133-148Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of 17-norleucine-VIP on gastroduodenal motility relative to serum VIP concentration and blockade of NOS.
Holle, G. E., Steinbach, E., Wünsch, E. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. G584-G590Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Glucagon-like peptide-1, - six important topics.
Holst, Jens Juul, 1995, Gastrointestinal Tract and Endocrine System.. Dordrecht/Boston/London: Kluwer Academic Publishers, p. 537-546Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Ileal release of glucagonlike peptide-1 (GLP-1): association with inhibition of gastric acid in humans
Layer, P., Holst, Jens Juul, Grandt, D. & Goebell, H., 1995, In: Digestive Disease Science. 40, p. 1074-82Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4207
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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