Jens Juul Holst

Jens Juul Holst

Professor


  1. 1997
  2. Published

    Enteroglucagon

    Holst, Jens Juul, 1997, In: Annual Reviews of Physiology. 59, p. 257-272

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Holder GLP-1 som nyt terapeutisk princip i diabetesbehandlingen hvad det lovede?

    Holst, Jens Juul, 1997, In: Tidsskrift for Diabetesbehandling. 2(7), p. 16-22

    Research output: Contribution to journalJournal articleResearch

  4. Published

    Non-insulin-dependent diabetes mellitus - new drugs?

    Holst, Jens Juul, 1997, In: Drug Discovery Today. 2, p. 128-129

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Posttranslational processing of proglucagon and postsecretory fate of proglucagon products.

    Holst, Jens Juul, Ørskov, C., Hartmann, B. & Deacon, Carolyn F., 1997, The Insulinotropic Gut Hormone Glucagon-like Peptide-1.. Basel: Karger, p. 24-48

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  6. Published

    The pathogenesis of non-insulin dependent diabetes mellitus involves a defective expression of the GIP receptor.

    Holst, Jens Juul, Gromada, J. L. & Nauck, M. A., 1997, In: Diabetologia. 40, p. 984-986

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem

    Larsen, P. J., Tang-Christensen, M., Holst, Jens Juul & Ørskov, Cathrine, 1997, In: Neuroscience. Vol. 77, No. 1, p. 257-270

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Glucagon-like peptide-1 (GLP-17-36amide) reduces hepatic glucose production indirectly through changes in insulin and glucagon secretion.

    Larsson, H., Holst, Jens Juul & Ahrén, B., 1997, In: Acta Phys. Scand.. 160, p. 413-422

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Altered postprandial motility in chronic pancreatitis: role of malabsorption.

    Layer, P., v.d. Ohe, M. R., Grandt, D., Holst, Jens Juul, Jansen, J. B. M. J., Holtmann, G., Keller, J. & Goebell, H., 1997, In: Today in Medicine. Gastroenterology. 112, p. 1624-1634

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans

    Nauck, M. A., Niedereichholz, U., Ettler, R., Holst, Jens Juul, Ørskov, Cathrine, Ritzel, R. & Schmiegel, W. H., Nov 1997, In: American Journal of Physiology (Consolidated). 273, 5 Pt 1, p. E981-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Effects of GLP-1 on gastric and pancreatic exocrine secretion and on gastrointestinal motility.

    Nauck, M. A., Schepp, W., Holst, Jens Juul & Schmiegel, W. H., 1997, The Insulintropic Gut Hormone Glucagon-Like Peptide-1, Front Diabetes vol. 13. Basel: Karger, p. 194-206

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  12. Published

    Glucagon-like peptide-1 (GLP-1) as a new therapeutic approach for type-2 diabetes.

    Nauck, M. A., Holst, Jens Juul, Willms, B. & Schmiegel, W., 1997, In: Exp. Clin. Endocrinol. Diabetes. 105, p. 187-195

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Gastrointestinal hormones and gastric emptying 20 years after jejunoileal bypass for massive obesity.

    Näslund, E., Grybäck, P., Hellström, P. M., Jacobsson, H., Holst, Jens Juul, Theodorsson, E. & Backmann, L., 1997, In: International Journal of Obesity. 21, p. 387-392

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Glucose absorption and the release of insulin, gastric inhibitory polypeptide, and glucagon-like peptide-1 in patients after total colectomy.

    Palnæs Hansen, C., Andreassen, J. & Holst, Jens Juul, 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 473-477

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The release of gastric inhibitory peptide, glucagon-like peptide-1, and insulin after oral glucose test in colectomized subjects.

    Palnæs Hansen, C., Andreassen, J. & Holst, Jens Juul, 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 473-477

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A double-blind placebo-controlled study on the effects of omeprazole on gut hormone secretion and gastric emptying rate.

    Rasmussen, L., Qvist, N., Øster-Jørgensen, E., Rehfeld, J. F., Holst, Jens Juul & Pedersen, S. A., 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 900-905

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Einfluss von subkutanem GLP-1 auf die frühe und langsame Phase der Insulin-sekretion nach intravenöser Glukosebelastung bei gesunden Probanden.

    Ritzelt, R., Ørskov, C., Holst, Jens Juul, Schmiegel, W. & Nauck, M. A., 1997, In: Diabetes und Stoffwechsel. 6, p. 64-69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Bombesin inhibits histamine release from the rat oxyntic mucosa by a somatostatin-dependent mechanism.

    Sandvik, A. K., Brenna, E., Sundan, A., Holst, Jens Juul & Waldum, H. L., 1997, In: Scandinavian Journal of Gastroenterology. 30, p. 427-432

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Circulating GRP and gastrin in fetal lambs in response to luminal infusion of fluids

    Sangild, Per Torp, Hilsted, L., Bjørnskov-Bartholdy, L., Holst, Jens Juul & Trahair, J. F., 1997.

    Research output: Contribution to conferencePaperResearch

  20. Published

    Use of antagonists to define tachykininergic control of intestinal motility in pigs.

    Schmidt, P. & Holst, Jens Juul, 1997, In: Peptides. 18, p. 373-379

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Effects of glucagon-like peptide-1 (7-36amide) on whole body protein metabolism in healthy man.

    Shalev, A., Holst, Jens Juul & Keller, U., 1997, In: European Journal of Clinical Investigation. 27, p. 10-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Short-term insulin treatment prevents the diabetogenic action of streptozotocin in rats

    Thulesen, J., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Jan 1997, In: Endocrinology. 138, 1, p. 62-68 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Short term insulin treatment prevents the diabetogenic action of streptozotocin in rats

    Thulesen, J., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 1997, In: Endokrinologiya. Vol. 138, No. 1, p. 62-68

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    PACAP 1-38 as neurotransmitter in the pig pancreas: PACAP-receptor activation revealed by the antagonist PACAP 6-38.

    Tornøe, K., Hannibal, J., Fahrenkrug, J. & Holst, Jens Juul, 1997, In: Am. J. Physiol.. 273, p. G436-G446

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Glucagon-like peptide-1 7-36amide and peptide YY have additive inhibitory effects on gastric acid secretion in man.

    Wettergren, A., Maina, P., Boesby, S. & Holst, Jens Juul, 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 552-555

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The inhibitory effect of glucagon-like peptide-1 (GLP-1) 7-36 amide on gastric acid secretion in humans depends on an intact vagal innervation.

    Wettergren, A., Wøjdemann, M., Meisner, S., Stadil, F. & Holst, Jens Juul, 1997, In: Gut. 40, p. 597-601

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 1996
  28. Published

    Impaired insulin-stimulated nonoxidative glucose metabolism in pancreas-kidney transplant recipients: dose-response effects of insulin on glucose turnover

    Christiansen, E., drb459, drb459, Tibell, A., Hother-Nielsen, O., Holst, Jens Juul, Pedersen, O. & Madsbad, Sten, 1996, In: Diabetes. 45, 9, p. 1267-75 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients

    Creutzfeldt, W. O., Kleine, N., Willms, B., Ørskov, Cathrine, Holst, Jens Juul & Nauck, M. A., Jun 1996, In: Diabetes Care. Supplement. 19, 6, p. 580-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    On the effects of glucagon-like peptide-1 on blood glucose regulation in normal and diabetic subjects

    Holst, Jens Juul, Toft-Nielsen, M. B., Ørskov, Cathrine, Nauck, M. & Willms, B., 26 Dec 1996, In: Annals of the New York Academy of Sciences. 805, p. 729-36 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  31. Published

    Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM

    Nauck, M. A., Wollschläger, D., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Willms, B., Dec 1996, In: Diabetologia. 39, 12, p. 1546-53 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Release of glucagon-like peptide 1 (GLP-1 [7-36 amide]), gastric inhibitory polypeptide (GIP) and insulin in response to oral glucose after upper and lower intestinal resections

    Nauck, M. A., Siemsglüss, J., Ørskov, Cathrine & Holst, Jens Juul, Mar 1996, In: Zeitschrift fur Gastroenterologie. 34, 3, p. 159-66 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I

    Ørskov, Cathrine, Poulsen, Steen Seier, Møller, Morten & Holst, Jens Juul, Jun 1996, In: Diabetes. 45, 6, p. 832-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Secretion of the incretin hormones glucagon-like peptide-1 and gastric inhibitory polypeptide correlates with insulin secretion in normal man throughout the day

    Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, Jul 1996, In: Scandinavian Journal of Gastroenterology. 31, 7, p. 665-70 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    GLP-1 does not not acutely affect insulin sensitivity in healthy man

    Orskov, L., Holst, Jens Juul, Møller, J., Ørskov, Cathrine, Møller, N., Alberti, K. G. & Schmitz, O., Oct 1996, In: Diabetologia. 39, 10, p. 1227-32 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Positive effects on plasma glucose & appetite by industrial modification of starch

    Raben, A., Andersen, K., Karberg, M. A., Holst, Jens Juul & Astrup, A., 1996. 1 p.

    Research output: Contribution to conferencePosterResearch

  37. Published

    Gastrin release in the fetal lamb in response to luminal infusion of amniotic fluid, milk or GRP

    Sangild, Per Torp, Hilsted, L., Bjørnskov-Bartholdy, L., Holst, Jens Juul & Trahair, J. F., 1996. 1 p.

    Research output: Contribution to conferencePaperResearch

  38. Published

    Tachykinins mediate vagal inhibition of gastrin secretion in pigs

    Schmidt, P., Poulsen, Steen Seier, Hilsted, Linda, Rasmussen, T. N. & Holst, Jens Juul, Oct 1996, In: Gastroenterology. 111, 4, p. 925-35 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1

    Serup, P., Jensen, J., Andersen, F. G., Jørgensen, Mette Christine, Blume, N., Holst, Jens Juul & Madsen, O. D., 20 Aug 1996, In: Proceedings of the National Academy of Sciences of the United States of America. 93, 17, p. 9015-20 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients

    Willms, B., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Nauck, M. A., Jan 1996, In: Endocrinology. 81, 1, p. 327-32 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 1995
  42. Published

    Potent inhibitory effects of transplantable rat glucagonomas and insulinomas on the respective endogenous islet cells are associated with pancreatic apoptosis.

    Blume, N., Skouv, J., Larsson, L., Holst, Jens Juul & Madsen, O. D., 1995, In: J. Clin. Invest.. 96, p. 2227-2235

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    The role of glucagon in the maintenance of euglycemia in the fed and the fasted state. Monoclonal antibody treatment as a tool in glucagon physiology in rats.

    Brand, C. L., Jørgensen, P. N., Svendsen, I., Kristensen, J. S., Knigge, U., Warberg, J. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. E469-E477

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Effect of endogenous hypergastrinemia on gastrin receptor expressing human colon carcinoma transplanted to athymic rats.

    Chu, M., Franzén, L., Rehfeld, J. F., Holst, Jens Juul & Borch, K., 1995, In: Today in Medicine. Gastroenterology. 109, p. 1415-1420

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Both subcutaneously and intravenously administered glucagon-like peptide-1 are rapidly degraded from the amino terminus in type II diabetic patients and in healthy subjects.

    Deacon, Carolyn F., Nauck, M. A., Nielsen, M. T., Pridal, L. & Holst, Jens Juul, 1995, In: Diabetes. 44, p. 1126-1131

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Degradation of glucagon-like peptide-1 in vitro yields an N-terminally truncated peptide which is a major endogenous metabolite in vivo.

    Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, p. 952-957

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Human colon produces fully processed glucagon-like peptide-1 (7-36 amide).

    Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: FEBS Letters. 372, p. 269-272.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Sympathoadrenal regulation of adrenocortical steroidogenesis

    Ehrhart-Bornstein, M., Bornstein, S. R., Gonzalez-Hernandez, J., Holst, Jens Juul, Watermann, M. R. & Scherbaum, W. A., 1995, In: Endocrine Research. 21, p. 13-24

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Physiological augmentation of amino acid-induced insulin secretion by GIP and GLP-I but not by CCK-8

    Fieseler, P., Bridenbaugh, S., Nustede, R., Martell, J., Nauck, M. A., Ørskov, Cathrine & Holst, Jens Juul, 1995, In: Am. J. Physiol.. Vol 268, p. E949-E955

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus.

    Hannibal, J., Mikkelsen, J. D., Clausen, H., Holst, Jens Juul, Wulff, B. S. & Fahrenkrug, J., 1995, In: Regulatory Peptides. 55, p. 133-148

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Effect of 17-norleucine-VIP on gastroduodenal motility relative to serum VIP concentration and blockade of NOS.

    Holle, G. E., Steinbach, E., Wünsch, E. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. G584-G590

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Human Glucagon-like peptide-1, - six important topics.

    Holst, Jens Juul, 1995, Gastrointestinal Tract and Endocrine System.. Dordrecht/Boston/London: Kluwer Academic Publishers, p. 537-546

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  53. Published

    Ileal release of glucagonlike peptide-1 (GLP-1): association with inhibition of gastric acid in humans

    Layer, P., Holst, Jens Juul, Grandt, D. & Goebell, H., 1995, In: Digestive Disease Science. 40, p. 1074-82

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4207