Jens Juul Holst

Jens Juul Holst

Professor


  1. 2009
  2. Published

    Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism

    Patti, M., Houten, S. M., Bianco, A. C., Bernier, R., Larsen, P. R., Holst, Jens Juul, Badman, M. K., Maratos-Flier, E., Mun, E. C., Pihlajamaki, J., Auwerx, J. & Goldfine, A. B., 2009, In: Obesity. 17, 9, p. 1671-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Effects of meal size and composition on incretin, alpha-cell, and beta-cell responses

    Rijkelijkhuizen, J. M., McQuarrie, K., Girman, C. J., Stein, P. P., Mari, A., Holst, Jens Juul, Nijpels, G. & Dekker, J. M., 2009, In: Metabolism - Clinical and Experimental.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Impaired glucose-induced glucagon suppression after partial pancreatectomy

    Schrader, H., Menge, B. A., Breuer, T. G. K., Ritter, P. R., Uhl, W., Schmidt, W. E., Holst, Jens Juul & Meier, J. J., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 8, p. 2857-63 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1

    Shang, Q., Saumoy, M., Holst, Jens Juul, Salen, G. & Xu, G., 2009, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 298, 3, p. G419-24

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Inhibition of neutral endopeptidase 24.11 does not potentiate the improvement in glycemic control obtained with dipeptidyl peptidase-4 inhibition in diabetic Goto-Kakizaki rats

    Simonsen, L., Pilgaard, S., Carr, R. D., Kanstrup, A. B., Holst, Jens Juul & Deacon, Carolyn F., 2009, In: Hormone and Metabolic Research. 41, 11, p. 851-3 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Long-term exendin-4 treatment delays natural deterioration of glycaemic control in diabetic Goto-Kakizaki rats

    Simonsen, L., Pilgaard, S., Orskov, C., Hartmann, Bolette, Holst, Jens Juul & Deacon, Carolyn F., 2009, In: Diabetes, Obesity and Metabolism. 11, 9, p. 884-90 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Incretin hormone secretion in women with polycystic ovary syndrome: roles of obesity, insulin sensitivity, and treatment with metformin

    phk294, phk294, Nilas, L., Madsbad, Sten & Holst, Jens Juul, 2009, In: Metabolism - Clinical and Experimental. 58, 5, p. 586-593

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Short-term treatment with olanzapine does not modulate gut hormone secretion: olanzapine disintegrating versus standard tablets

    Vidarsdottir, S., Roelfsema, F., Streefland, T., Holst, Jens Juul, Rehfeld, Jens Frederik & Pijl, H., 2009, In: European Journal of Endocrinology. 162, 1, p. 75-83 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Incretin hormones and diabetes mellitus

    Vilsbøll, Tina, Knop, Filip Krag, Deacon, Carolyn F. & Holst, Jens Juul, 2009, Therapeutic Strategies in Diabetes. Stehouwer, C. D. A. & Schaper, N. (eds.). Oxford: Clinical Publishing, p. 99-114

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  11. Published

    The spectrum of antidiabetic actions of GLP-1 in patients with diabetes

    Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2009, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 23, 4, p. 453-62 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Hyperglycemia acutely lowers the postprandial excursions of glucagon-like Peptide-1 and gastric inhibitory polypeptide in humans

    Vollmer, K., Gardiwal, H., Menge, B. A., Goetze, O., Deacon, Carolyn F., Schmidt, W. E., Holst, Jens Juul & Meier, J. J., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1379-85 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Differential effect of PYY1-36 and PYY3-36 on gastric emptying in man

    Witte, A., Grybäck, P., Holst, Jens Juul, Hilsted, Linda, Hellström, P. M., Jacobsson, H. & Schmidt, P. T., 2009, In: Regulatory Peptides. 158, 1-3, p. 57-62 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Effect of viscosity on appetite and gastro-intestinal hormones

    Zijlstra, N., Mars, M., de Wijk, R. A., Westerterp-Plantenga, M. S., Holst, Jens Juul & de Graaf, C., 2009, In: Physiology & Behavior. 97, 1, p. 68-75 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2008
  16. Published

    GLP-1: physiological effects and potential therapeutic applications

    Aaboe, K., Krarup, T., Madsbad, Sten & Holst, Jens Juul, Nov 2008, In: Diabetes, Obesity and Metabolism Online. 10, 11, p. 994-1003 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    GLP-1: physiological effects and potential therapeutic applications

    Aaboe, K., Krarup, T., Madsbad, Sten, Holst, Jens Juul, Aaboe, K., Krarup, T., Madsbad, Sten & Holst, J. J., 2008, In: Diabetic Medicine. 10, 11, p. 994-1003 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

    Aaboe, K., Knop, Filip Krag, Vilsboll, T., Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Functional ontogeny of the proglucagon-derived peptide axis in the premature human neonate

    Amin, H., Holst, Jens Juul, Hartmann, B., Wallace, L., Wright, J. & Sigalet, D. L., 2008, In: Pediatrics. 121, 1, p. E180-E186 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Functional ontogeny of the proglucagon-derived peptide axis in the premature human neonate

    Amin, H., Holst, Jens Juul, Hartmann, Bolette, Wallace, L., Wright, J. & Sigalet, D. L., Jan 2008, In: Pediatrics. 121, 1, p. e180-6

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Measurements Inhibition of DPP-4 evokes pancreatic and extra-pancreatic mechanisms that improve glucose homeostasis in type 2 diabetes mellitus.

    Azuma, K., Radikova, Z., Mancino, J., Toledo, F., Thomas, E., Kangani, C., Dalla Man, C., Cobelli, C., Holst, Jens Juul, Deacon, Carolyn F., He, Y., Ligueros-Saylan, M., Serra, D. & Kelley, D., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, p. 459-463

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Overconsumption and obesity: peptides and susceptibility to weight gain

    Blundell, J. E., Levin, F., King, N. A., Barkeling, B., Gustafsson, T., Gustafson, T., Hellstrom, P. M., Holst, Jens Juul & Naslund, E., 7 Aug 2008, In: Regulatory Peptides. 149, 1-3, p. 32-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Overconsumption and obesity: Peptides and susceptibility to weight gain

    Blundell, J. E., Levin, F., King, N. A., Barkeling, B., Gustafson, T., Hellstrom, P. M., Holst, Jens Juul & Naslund, E., 2008, In: Regulatory Peptides. 149, 1-3, p. 32-38 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Glucagon-like peptide-2 increases mesenteric blood flow in humans

    Bremholm, L., Hornum, Mads, Henriksen, B. M., Larsen, S. & Holst, Jens Juul, 2008, In: Scandinavian Journal of Gastroenterology. 44, 3, p. 314-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    DPP-4 inhibitor therapy: new directions in the treatment of type 2 diabetes

    Deacon, Carolyn F., Carr, R. D. & Holst, Jens Juul, 2008, In: Frontiers in Bioscience. 13, p. 1780-94 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Comparison of the effects on insulin resistance and glucose tolerance of 6-mo high-monosaturated-fat, low-fat, and control diets

    Due, A. P., Larsen, T. M., Hermansen, K., Stender, Steen, Holst, Jens Juul, Toubro, S., Martinussen, Torben & Astrup, A., 2008, In: American Journal of Clinical Nutrition. 87, 4, p. 855-862 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Comparison of the effects on insulin resistance and glucose tolerance of 6-mo high-monounsaturated-fat, low-fat, and control diets

    Due, A. P., Larsen, T. M., Hermansen, K., Stender, Steen, Holst, Jens Juul, Toubro, S., Martinussen, Torben & Astrup, A., 2008, In: American Journal of Clinical Nutrition. 87, 4, p. 855-862 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Meal-induced compositional changes in blood and saliva in persons with bulimia nervosa

    Dynesen, A. W., Jensen, A. B., Astrup, A., Petersson, B., Holst, Jens Juul & Nauntofte, B., 2008, In: American Journal of Clinical Nutrition. 87, 1, p. 12-22 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon-like peptide-1-(7-36)-amide-1, cholecystokinin, and peptide YY concentrations

    Ellrichmann, M., Kapelle, M., Ritter, P. R., Holst, Jens Juul, Herzig, K. H., Schmidt, W. E., Schmitz, F. & Meier, J. J., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 3995-3998 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon-like peptide-1-(7-36)-amide-1, cholecystokinin, and peptide YY concentrations

    Ellrichmann, M., Kapelle, M., Ritter, P. R., Holst, Jens Juul, Herzig, K., Schmidt, W. E., Schmitz, F. & Meier, J. J., Oct 2008, In: The Journal of clinical endocrinology and metabolism. 93, 10, p. 3995-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Orlistat accelerates gastric emptying and attenuates GIP release in healthy subjects

    Enç, F. Y., Ones, T., Akin, H. L., Dede, F., Turoglu, H. T., Ulfer, G., Bekiroglu, N., Haklar, G., Rehfeld, Jens Frederik, Holst, Jens Juul, Ulusoy, N. B. & Imeryüz, N., 2008, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 296, 3, p. G482-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Impaired fasting glycaemia vs impaired glucose tolerance: similar impairment of pancreatic alpha and beta cell function but differential roles of incretin hormones and insulin action

    Faerch, K., Vaag, Allan, Holst, Jens Juul, Glümer, C., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2008, In: Diabetologia. 51, 5, p. 853-61 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Determinants of glycemic charges in normoglycemic individuals

    Faerch, K., Vaag, Allan, Holst, Jens Juul, Hansen, T., Glumer, C. & Borch-Johnsen, K., 2008, In: Diabetes. Suppl. 1, p. A659-A659 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  34. Published

    Progression from normal glucose tolerance to impaired fasting glycaemia and impaired glucose tolerance: differential roles of insulin resistance and beta cell dysfunction

    Faerch, K., Vaag, Allan, Holst, Jens Juul, Pedersen, O., Glumer, C. & Borch-Johnsen, K., 2008, In: Diabetologia. 51, Suppl. 1, p. S85-S86

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Natural history of insulin sensitivity and insulin secretion in the progression from normal glucose tolerance to impaired fasting glycemia and impaired glucose tolerance: the Inter99 study

    Faerch, K., Vaag, Allan, Holst, Jens Juul, Hansen, Torben, Jørgensen, T. & Borch-Johnsen, K., 2008, In: Diabetes Care. 32, 3, p. 439-44 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes

    Foley, J. E., Ligueros-Saylan, M., He, Y., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., Oct 2008, In: Hormone and Metabolic Research. Supplement. 40, 10, p. 727-30 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Effect of Vildagliptin on Glucagon Concentration During Meals in Patients with Type 1 Diabetes

    Foley, J. E., Ligueros-Saylan, M., He, Y. L., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., 2008, In: Hormone and Metabolic Research. 40, 10, p. 727-730 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomized patients with distal ileostomy or jejunostomy and short-bowel syndrome

    Gottschalck, I. B., Jeppesen, Palle Bekker, Hartmann, B., Holst, Jens Juul & Henriksen, D. B., 2008, In: Scandinavian Journal of Gastroenterology. 43, 11, p. 1304-1310 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomized patients with distal ileostomy or jejunostomy and short-bowel syndrome

    Gottschalck, I. B., Jeppesen, Palle Bekker, Hartmann, Bolette, Holst, Jens Juul & Henriksen, D. B., 2008, In: Scandinavian Journal of Gastroenterology. 43, 11, p. 1304-10 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Reduction in bone resorption by exogenous glucagon-like peptide-2 administration requires an intact gastrointestinal tract

    Gottschalck, I. B., Jeppesen, Palle Bekker, Holst, Jens Juul & Henriksen, D. B., Aug 2008, In: Scandinavian Journal of Gastroenterology. 43, 8, p. 929-37 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Reduction in bone resorption by exogenous glucagon-like peptide-2 administration requires an intact gastrointestinal tract

    Gottschalck, I. B., Jeppesen, Palle Bekker, Holst, Jens Juul & Henriksen, D. B., 2008, In: Scandinavian Journal of Gastroenterology. 43, 8, p. 929-937 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Oral glutamine increases circulating glucagon-like peptide 1, glucagon, and insulin concentrations in lean, obese, and type 2 diabetic subjects

    Greenfield, J. R., Farooqi, I. S., Keogh, J. M., Henning, E., Habib, A. M., Blackwood, A., Reimann, F., Holst, Jens Juul & Gribble, F. M., 2008, In: American Journal of Clinical Nutrition. 89, 1, p. 106-13 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    GLP-1 suppresses gastrointestinal motility and inhibits the migrating motor complex in healthy subjects and patients with irritable bowel syndrome

    Hellstrom, P. M., Naslund, E., Edholm, T., Schmidt, P. T., Kristensen, J., Theodorsson, E., Holst, Jens Juul & Efendic, S., 2008, In: Neurogastroenterology and Motility. 20, 6, p. 649-659 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    GLP-1 suppresses gastrointestinal motility and inhibits the migrating motor complex in healthy subjects and patients with irritable bowel syndrome

    Hellström, P. M., Näslund, E., Edholm, T., Schmidt, P. T., Kristensen, J., Theodorsson, E., Holst, Jens Juul & Efendic, S., Jun 2008, In: Neurogastroenterology and Motility Online. 20, 6, p. 649-59 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Glucagon-like peptide-1, glucose homeostasis and diabetes.

    Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, 2008, In: Trends in Molecular Medicine. 14, 4, p. 161-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Overview of incretin hormones.

    Holst, Jens Juul & Lasalle, J., 2008, In: Journal of Family Practice. 57, 9, p. 53-59

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    The incretin system and its role in type 2 diabetes mellitus

    Holst, Jens Juul, Vilsbøll, Tina & Deacon, Carolyn F., 2008, In: Molecular and Cellular Endocrinology. 297, 1-2, p. 127-136 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    The physiology and pharmacology of incretins in type 2 diabetes mellitus

    Holst, Jens Juul, 2008, In: Diabetes, Obesity and Metabolism. 10, Suppl. 3, p. 14-21 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

    Højberg, P. V., Vilsbøll, Tina, Rabøl, R., Knop, Filip Krag, Bache, M., Krarup, T., Holst, Jens Juul & Madsbad, Sten, 2008, In: Diabetologia. 52, 2, p. 199-207 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes

    Højberg, P. V., Vilsbøll, T., Zander, M., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, Nov 2008, In: Diabetic Medicine Online. 25, 11, p. 1268-75 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes

    Højberg, P. V., Zander, M., Vilsbøll, T., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, 1 Apr 2008, In: Diabetologia. 51, 4, p. 632-640 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    The effects of variations in dose and method of administration on glucagon like peptide-2 activity in the rat

    Kaji, T., Tanaka, H., Holst, Jens Juul, Redstone, H., Wallace, L., Heuval, E. D. & Sigalet, D. L., 2008, In: European Journal of Pharmacology. 596, 1-3, p. 138-145 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4207