Signe Mathiasen
Assistant Professor, Tenure Track Assistant Professor
Molecular and Translational Pharmacology
Blegdamsvej 3, 2200 København N., 18 Bygning 18, Building: 18-5-42
Member of:
- Published
Adhesion G protein‐coupled receptor's structure, function and role in biology—Status from the 10th adhesion GPCR workshop in Copenhagen, 2022
Rosenkilde, Mette & Mathiasen, Signe, 2023, In: Basic & clinical pharmacology & toxicology. 133, 4, p. 281-284Research output: Contribution to journal › Editorial › Research › peer-review
Agonist-induced formation of unproductive receptor-G12 complexes
Okashah, N., Wright, S. C., Kawakami, K., Mathiasen, Signe, Zhou, J., Lu, S., Javitch, J. A., Inoue, A., Bouvier, M. & Lambert, N. A., 1 Sep 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 35, p. 21723-21730 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biophysical characterization of GPCR oligomerization
Mathiasen, Signe, 2013, Department of Chemistry, Faculty of Science, University of Copenhagen. 167 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature
Miller, S. E., Mathiasen, Signe, Bright, N. A., Pierre, F., Kelly, B. T., Kladt, N., Schauss, A., Merrifield, C. J., Stamou, Dimitrios, Höning, S. & Owen, D. J., 2015, In: Developmental Cell. 33, 2, p. 163-175 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Developing an Assay to Probe Activtion and Conformational Dynamics of beta 2-Adrenergic Receptor on Single Molecule Level
Veshaguri, S., Tutkus, M., Lundgaard, C. V., Tonnesen, A., Mathiasen, Signe, Jorgensen, S. K., Iversen, L., Hatzakis, Nikos, Rasmussen, Søren Gøgsig Faarup & Stamou, Dimitrios, 2013, In: Biophysical Journal. 104, 2, 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Electronic tuning of self-healing fluorophores for live-cell and single-molecule imaging
Zheng, Q., Jockusch, S., Zhou, Z., Altman, R. B., Zhao, H., Asher, W., Holsey, M., Mathiasen, Signe, Geggier, P., Javitch, J. A. & Blanchard, S. C., 2016, In: Chemical Science. 8, 1, p. 755-762 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extreme vetting of dopamine receptor oligomerization
Asher, W. B., Mathiasen, Signe, Holsey, M. D., Grinnell, S. G., Lambert, N. A. & Javitch, J. A., 2017, Receptors. Humana Press, p. 99-127 29 p. (Receptors, Vol. 33).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3
Mathiasen, Signe, Palmisano, T., Perry, N. A., Stoveken, H. M., Vizurraga, A., McEwen, D. P., Okashah, N., Langenhan, T., Inoue, A., Lambert, N. A., Tall, G. G. & Javitch, J. A., Dec 2020, In: Nature Chemical Biology. 16, 12, p. 1343–1350Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of PI(3,4,5)P3-Mediated beta-Arrestin-1 Recruitment on Structure of Asymmetric Lipid Bilayers: Biophysical Society Annual Meeting. Baltimore, Maryland, Febr. 7-11 2015
Nzulumike, A. N. O., Mathiasen, Signe, Mahoney, J. P., Cardenas Gomez, M., Stamou, Dimitrios & Mortensen, Kell, 7 Feb 2015, In: Biophysical Journal. 108, 2, Suppl., p. 342A-342AResearch output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Membrane curvature bends the laws of physics and chemistry
Iversen, L., Mathiasen, Signe, Larsen, J. B. & Stamou, Dimitrios, 2015, In: Nature Chemical Biology. 11, 11, p. 822-825 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nanoscale high-content analysis using compositional heterogeneities of single proteoliposomes
Mathiasen, Signe, Christensen, S. M., Fung, J. J., Rasmussen, Søren Gøgsig Faarup, Fay, J. F., Jørgensen, S. K., Veshaguri, S., Farrens, D. L., Kiskowski, M., Kobilka, B. & Stamou, Dimitrios, 2014, In: Nature Methods. 11, p. 931-934 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel Fluorescent Ligands Enable Single-Molecule Localization Microscopy of the Dopamine Transporter
Guthrie, D. A., Klein Herenbrink, Carmen, Lycas, M. D., Ku, T., Bonifazi, A., Devree, B. T., Mathiasen, Signe, Javitch, J. A., Grimm, J. B., Lavis, L., Gether, Ulrik & Newman, A. H., 2020, In: ACS Chemical Neuroscience. 11, 20, p. 3288-3300 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Particle-dissociating peptides
Brown, Stanley & Mathiasen, Signe, 4 Jan 2011, In: Advanced Materials. 23, 1, p. 132-135 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Re-routing GPR56 signalling using Gα12/13 G protein chimeras
Faas, Felix, Nørskov, Amalie, Holst, Peter Johannes, Andersson, A. M., Qvortrup, K., Mathiasen, Signe & Rosenkilde, Mette, 2023, In: Basic and Clinical Pharmacology and Toxicology. 133, 4, p. 378-389Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single Proteoliposome High-Content Analysis Reveals Differences in the Homo-Oligomerization of GPCRs
Walsh, S. M., Mathiasen, Signe, Christensen, S. M., Fay, J. F., King, C., Provasi, D., Borrero, E., Rasmussen, Søren Gøgsig Faarup, Fung, J. J., Filizola, M., Hristova, K., Kobilka, B., Farrens, D. L. & Stamou, Dimitrios, 2018, In: Biophysical Journal. 115, 2, p. 300-312 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Single-molecule FRET imaging of GPCR dimers in living cells
Asher, W. B., Geggier, P., Holsey, M. D., Gilmore, G. T., Pati, A. K., Meszaros, J., Terry, D. S., Mathiasen, Signe, Kaliszewski, M. J., McCauley, M. D., Govindaraju, A., Zhou, Z., Harikumar, K. G., Jaqaman, K., Miller, L. J., Smith, A. W., Blanchard, S. C. & Javitch, J. A., 2021, In: Nature Methods. 18, 4, p. 397-405 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-molecule analysis of ligand efficacy in β2AR-G-protein activation
Gregorio, G. G., Masureel, M., Hilger, D., Terry, D. S., Juette, M., Zhao, H., Zhou, Z., Perez-Aguilar, J. M., Hauge, M., Mathiasen, Signe, Javitch, J. A., Weinstein, H., Kobilka, B. K. & Blanchard, S. C., 2017, In: Nature. 547, 7661, p. 68–73Research output: Contribution to journal › Journal article › Research › peer-review
ID: 16152685
Most downloads
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367
downloads
CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
11
downloads
Single-molecule FRET imaging of GPCR dimers in living cells
Research output: Contribution to journal › Journal article › Research › peer-review