Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- 2004
- Published
Milrinone efficiently potentiates insulin secretion induced by orally but not intravenously administered glucose in C57BL6J mice
Degerman, E., Manganiello, V., Holst, Jens Juul & Ahren, B., 2004, In: Eur. J. Pharmacol.. 498, p. 319-323Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neural regulation of glucagon-like peptide- 1 secretion in pigs
Hansen, L., Lampert, S., Mineo, H. & Holst, Jens Juul, 2004, In: Am. J. Physiol.. 287, p. E939-E947Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neutral endopeptidase 24.11 is important for the degradation of both endogenous and exogenous glucagon in anesthetized pigs.
Trebbien, R., Klarskov, L., Olesen, M., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 3, p. E431-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the physiology of GIP and GLP-1
Holst, Jens Juul, 2004, In: Horm Metab Res. 36, p. 747-754Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Onset of small intestinal atrophy is associated with reduced intestinal blod flow in TNP-fed neonatal piglets
Niinikoski, H., Stoll, B., Guam, X., Kansagra, K., Lambert, B., Hartmann, B., Holst, Jens Juul & Burrin, D. G., 2004, In: Journal of Nutrition. 134, p. 1467-1474Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma GLP-2 levels and intestinal markers in the juvenile pig during intestinal adaptation: effects of different diet regimens
Paris, M. C. J., Fuller, P. J., Taylor, R. G., Nagy, E., Sourial, M., Catto-Smith, T., Hartmann, B., Holst, Jens Juul & Bines, J. E., 2004, In: Dig. Dis. Sci.. 49, p. 1688-1695Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prandial subcutaneous injections of glucagons-like peptide- 1 cause weight loss in obese human subjects
Näslund, E., King, N., Mansten, S., Adner, N., Holst, Jens Juul, Gutniak, M. & Hellström, P., 2004, In: Br.J.Nutr.. 91, p. 439-446Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction of beta cell mass: partial insulin secretory compensation from the residual beta cell population in the nicotinamide-streptozotocin Göttingen minipig after oral glucose in vivo and in the perfused pancreas
Larsen, M. O., Rolin, B., Gotfredsen, C. F., Carr, R. D. & Holst, Jens Juul, 2004, In: Diabetologia. 47, p. 1873-1878Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction of nocturnal rise in bone resorption by subcutaneous GLP-2.
Henriksen, D. B., Alexandersen, P., Byrjalsen, I., Hartmann, B., Bone, H. G., Christiansen, C. & Holst, Jens Juul, 2004, In: Bone. 34, 1, p. 140-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans.
Holst, Jens Juul & Gromada, J., 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 2, p. E199-206Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of incretin hormones (GIP and GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes.
Nauck, M. A., El-Ouaghlidi, A., Gabrys, B., Hücking, K., Holst, Jens Juul, Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Meier, J. J., 2004, In: Regulatory Peptides. 122, 3, p. 209-17 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion, degradation, and elimination of glucagon-like peptide 1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjects.
Meier, J. J., Nauck, M. A., Kranz, D., Holst, Jens Juul, Deacon, Carolyn F., Gaeckler, D., Schmidt, W. E. & Gallwitz, B., 2004, In: Diabetes. 53, 3, p. 654-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Similar gastric emptying but greater gastric secretion and GIP release after the ingestion of peptide hydrolysates in man
Calbet, J. A. L. & Holst, Jens Juul, 2004, In: Eur J Nutrition. 43, p. 127-139Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stimulation of insulin secretion by intravenous bolus injection and continuous infusion of gastric inhibitory polypeptide in patients with type 2 diabetes and healthy control subjects.
Meier, J. J., Gallwitz, B., Kask, B., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2004, In: Diabetes. 53 Suppl 3, p. S220-4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation following and 80% jejunoileal resection in neonatal pigs
Bartholome, A. L., Albin, D. M., Baker, D. H., Holst, Jens Juul & Tappenden, K. A., 2004, In: J Parenter Enteral Nutr. 28, p. 210-223Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The incretin approach for diabetes treatment: modulation of islet hormone release by GLP-1 agonism.
Holst, Jens Juul & Ørskov, Cathrine, 2004, In: Diabetes. 53 Suppl 3, p. S197-204Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ¤use of glycaemic index tables to predict glycaemic index of composite breakfast meals
Flint, A., Møller, B. K., Raben, Anne, Pedersen, D., Tetens, I., Holst, Jens Juul & Astrup, A., 2004, In: British Journal of Nutrition. 91, 6, p. 979-989 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors.
Holst, Jens Juul, 2004, In: Expert Opinion on Emerging Drugs. 9, 1, p. 155-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antihyperglycemic effects of stevioside in type 2 diabetic subjects
Gregersen, S., Jeppesen, P. B., Holst, Jens Juul & Hermansen, K., Jan 2004, In: Metabolism. 53, 1, p. 73-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholecystokinin inhibits gastrin secretion independently of paracrine somatostatin secretion in the pig
Schmidt, P. T., Hansen, L., Hilsted, Linda & Holst, Jens Juul, Mar 2004, In: Scandinavian Journal of Gastroenterology. 39, 3, p. 217-21 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretins, insulin secretion and Type 2 diabetes mellitus
Vilsbøll, T. & Holst, Jens Juul, Mar 2004, In: Diabetologia. 47, 3, p. 357-66 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intravenous glucagon-like peptide 1 normalizes blood glucose after major surgery in patients with type 2 diabetes
Meier, J. J., Weyhe, D., Michaely, M., Senkal, M., Zumtobel, V., Nauck, M. A., Holst, Jens Juul, Schmidt, W. E. & Gallwitz, B., Mar 2004, In: New Horizons (Baltimore). 32, 3, p. 848-51 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prandial subcutaneous injections of glucagon-like peptide-1 cause weight loss in obese human subjects
Näslund, E., King, N., Mansten, S., Adner, N., Holst, Jens Juul, Gutniak, M. & Hellström, P. M., Mar 2004, In: The British Journal of Nutrition. 91, 3, p. 439-46 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric inhibitory polypeptide does not inhibit gastric emptying in humans
Meier, J. J., Goetze, O., Anstipp, J., Hagemann, D., Holst, Jens Juul, Schmidt, W. E., Gallwitz, B. & Nauck, M. A., Apr 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 286, 4, p. E621-5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 inhibits antral emptying in man, but is not as potent as glucagon-like peptide-1
Nagell, C. F., Wettergren, A., Pedersen, J. F., Mortensen, D. & Holst, Jens Juul, Apr 2004, In: Scandinavian Journal of Gastroenterology. 39, 4, p. 353-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Blood glucose control in healthy subject and patients receiving intravenous glucose infusion or total parenteral nutrition using glucagon-like peptide 1
Nauck, M. A., Walberg, J., Vethacke, A., El-Ouaghlidi, A., Senkal, M., Holst, Jens Juul, Gallwitz, B., Gallwitz, J. B., Schmidt, W. E. & Schmiegel, W., 15 Apr 2004, In: Regulatory Peptides. 118, 1-2, p. 89-97 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 secretion is influenced by perfusate glucose concentration and by a feedback mechanism involving somatostatin in isolated perfused porcine ileum
Hansen, L., Hartmann, Bolette, Mineo, H. & Holst, Jens Juul, 15 Apr 2004, In: Regulatory Peptides. 118, 1-2, p. 11-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors
Hansotia, T., Baggio, L. L., Delmeire, D., Hinke, S. A., Yamada, Y., Tsukiyama, K., Seino, Y., Holst, Jens Juul, Schuit, F. & Drucker, D. J., May 2004, In: Diabetes. 53, 5, p. 1326-35 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance
Rask, E., Olsson, T., Söderberg, S., Holst Jj, J. J., Tura, A., Pacini, G., Ahrén, B. & Holst, Jens Juul, May 2004, In: Metabolism. 53, 5, p. 624-31 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying, gastric secretion and enterogastrone response after administration of milk proteins or their peptide hydrolysates in humans
Calbet, J. A. L. & Holst, Jens Juul, Jun 2004, In: European Journal of Nutrition. 43, 3, p. 127-39 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Onset of small intestinal atrophy is associated with reduced intestinal blood flow in TPN-fed neonatal piglets
Niinikoski, H., Stoll, B., Guan, X., Kansagra, K., Lambert, B. D., Stephens, J., Hartmann, Bolette, Holst, Jens Juul & Burrin, D. G., Jun 2004, In: Journal of Nutrition. 134, 6, p. 1467-74 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 2 (GLP-2) accelerates the growth of colonic neoplasms in mice
Thulesen, J., Hartmann, Bolette, Hare, K. J., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Aug 2004, In: Gut. 53, 8, p. 1145-1150 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal piglets
Bartholome, A. L., Albin, D. M., Baker, D. H., Holst, Jens Juul & Tappenden, K. A., 5 Aug 2004, In: Journal of Parenteral and Enteral Nutrition. 28, 4, p. 210-22; discussion 222-3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 levels in infants with intestinal dysfunction
Sigalet, D. L., Martin, G., Meddings, J., Hartman, B. & Holst, Jens Juul, Sep 2004, In: Pediatric Research. 56, 3, p. 371-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma GLP-2 levels and intestinal markers in the juvenile pig during intestinal adaptation: effects of different diet regimens
Paris, M. C., Fuller, P. J., Carstensen, Bendix, Nagy, E., Taylor, R. G., Sourial, M., Holst, Jens Juul, Hartmann, Bolette & Binesm, J. E., Oct 2004, In: Digestive Diseases and Sciences. 49, 10, p. 1688-95 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycemia and insulinemia in healthy subjects after lactose-equivalent meals of milk and other food proteins: the role of plasma amino acids and incretins
Nilsson, M., Stenberg, M., Frid, A. H., Holst, Jens Juul & Björck, I. M. E., Nov 2004, In: Uden navn. 80, 5, p. 1246-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neural regulation of glucagon-like peptide-1 secretion in pigs
Hansen, L., Lampert, S., Mineo, H. & Holst, Jens Juul, Nov 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 5, p. E939-47Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Alpha-Glucosidase inhibition (Acarbose) fails to enhance secretion of glucagons-like peptide 1(7-36 amide) and to delay gastric emptying in type 2 diabetic patients
Hücking, K., Kostic, Z., Pox, C., Ritzel, R., Holst, Jens Juul, Schmiegel, W. & Nauck, M. A., 2005, In: Diabet. Med.. 22, p. 470-476Research output: Contribution to journal › Journal article › Research
- Published
Defective glucose and lipid metabolism in human immunodeficiency virus-infected patients with lipodystrophy involve liver, muscle tissue and pancreatic beta-cells.
Haugaard, S. B., Andersen, Ove, Dela, Flemming, Holst, Jens Juul, Storgaard, H., Fenger, M., Iversen, J., Madsbad, Sten, Haugaard, S. B., Andersen, Ove, Dela, F., Holst, J. J., Storgaard, H., Fenger, M., Iversen, J. & Madsbad, Sten, 2005, In: European Journal of Endocrinology. 152, 1, p. 103-112 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential postprandial lipoprotein responses in type 2 diabetic men with and without clinical evidence of a former myocardial infarction.
Carstensen, M., Thomsen, C., Gotzsche, O., Holst, Jens Juul, Schrezenmeir, J. & Hermansen, K., 2005, In: The review of diabetic studies : RDS. 1, 4, p. 175-84 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase IV inhibitors: a promising new therapeutic approach for the management of type 2 diabetes.
Deacon, Carolyn F. & Holst, Jens Juul, 2005, In: International Journal of Biochemistry & Cell Biology. 38, 5-6, p. 831-44 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility.
Miki, T., Minami, K., Shinozaki, H., Matsumura, K., Saraya, A., Ikeda, H., Yamada, Y., Holst, Jens Juul & Seino, S., 2005, In: Diabetes. 54, 4, p. 1056-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of whey on blood glucose and insulin responses to composite breakfast and lunch meals in type 2 diabetic subjects.
Frid, A. H., Nilsson, M., Holst, Jens Juul & Björck, I. M. E., 2005, In: American Journal of Clinical Nutrition. 82, 1, p. 69-75 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhanced glucagon-like peptide- 1 (GLP-1) response to oral glucose in glucose intolerant HIV-infected patients on antiretroviral therapy
Andersen, O., Haugaard, S. B., Holst, Jens Juul, Deacon, Carolyn F., Iversen, J., Andersen, U. B., Nielsen, J. O. & Madsbad, S., 2005, In: HIV Medicine. 6, p. 91-98Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enteral feeding without pancreatic stimulation.
Kaushik, N., Pietraszewski, M., Holst, Jens Juul & O'Keefe, S. J. D., 2005, In: Pancreas. 31, 4, p. 353-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erythromycin antagonises the deceleration of gastric emptying by glucagon-like peptide-1 (GLP)-1 and unmasks its insulinotropic effect in healthy subjects
Meier, J. J., Kemmeries, G., Holst, Jens Juul & Nauck, M. A., 2005, In: Diabetes. 54, p. 2212-2218Research output: Contribution to journal › Journal article › Research
- Published
Evidence for an endocrine pancreatico-gastric axis: The role of pancreatic polypeptide in gastric emptying and short term metabolic control
Schmidt, P. T., Näslund, E., Grybäck, P., Jacobsson, H., Holst, Jens Juul, Hilsted, L. & Hellström, P. M., 2005, In: J. Clin. Endocrinol. Metab.. 90, p. 5241-5246Research output: Contribution to journal › Journal article › Research
- Published
Evidence of an association between the Arg72 allele of the peptide YY and increased risk of type 2 diabetes
Torekov, Signe Sørensen, Larsen, L. H., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Holst, Jens Juul, Madsen, O. D., Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Diabetes. 54, 7, p. 2261-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence of an association between the Arg72-allele of the peptide YY (PYY) and increased risk of type 2 diabetes
Torekov, S. S., Larsen, L. H., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Holst, Jens Juul, Madsen, O. D., Hansen, T. & Pedersen, O., 2005, In: Diabetes. 54, p. 2261-2265Research output: Contribution to journal › Journal article › Research
- Published
Exenatide augments first and second phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes
Fehse, F., Trautmann, M., Holst, Jens Juul, Halseth, A. E., Nanyakkara, N., Nielsen, L., Fineman, M. S. D., Kim, D. D. & Nauck, M. A., 2005, In: J. Clin. Endocrinol. Metab.. 90, p. 5991-5997Research output: Contribution to journal › Journal article › Research
ID: 4207
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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