Jens Juul Holst

Jens Juul Holst

Professor


  1. 2004
  2. Published

    Milrinone efficiently potentiates insulin secretion induced by orally but not intravenously administered glucose in C57BL6J mice

    Degerman, E., Manganiello, V., Holst, Jens Juul & Ahren, B., 2004, In: Eur. J. Pharmacol.. 498, p. 319-323

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Neural regulation of glucagon-like peptide- 1 secretion in pigs

    Hansen, L., Lampert, S., Mineo, H. & Holst, Jens Juul, 2004, In: Am. J. Physiol.. 287, p. E939-E947

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Neutral endopeptidase 24.11 is important for the degradation of both endogenous and exogenous glucagon in anesthetized pigs.

    Trebbien, R., Klarskov, L., Olesen, M., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 3, p. E431-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    On the physiology of GIP and GLP-1

    Holst, Jens Juul, 2004, In: Horm Metab Res. 36, p. 747-754

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Onset of small intestinal atrophy is associated with reduced intestinal blod flow in TNP-fed neonatal piglets

    Niinikoski, H., Stoll, B., Guam, X., Kansagra, K., Lambert, B., Hartmann, B., Holst, Jens Juul & Burrin, D. G., 2004, In: Journal of Nutrition. 134, p. 1467-1474

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Plasma GLP-2 levels and intestinal markers in the juvenile pig during intestinal adaptation: effects of different diet regimens

    Paris, M. C. J., Fuller, P. J., Taylor, R. G., Nagy, E., Sourial, M., Catto-Smith, T., Hartmann, B., Holst, Jens Juul & Bines, J. E., 2004, In: Dig. Dis. Sci.. 49, p. 1688-1695

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Prandial subcutaneous injections of glucagons-like peptide- 1 cause weight loss in obese human subjects

    Näslund, E., King, N., Mansten, S., Adner, N., Holst, Jens Juul, Gutniak, M. & Hellström, P., 2004, In: Br.J.Nutr.. 91, p. 439-446

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Reduction of beta cell mass: partial insulin secretory compensation from the residual beta cell population in the nicotinamide-streptozotocin Göttingen minipig after oral glucose in vivo and in the perfused pancreas

    Larsen, M. O., Rolin, B., Gotfredsen, C. F., Carr, R. D. & Holst, Jens Juul, 2004, In: Diabetologia. 47, p. 1873-1878

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Reduction of nocturnal rise in bone resorption by subcutaneous GLP-2.

    Henriksen, D. B., Alexandersen, P., Byrjalsen, I., Hartmann, B., Bone, H. G., Christiansen, C. & Holst, Jens Juul, 2004, In: Bone. 34, 1, p. 140-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans.

    Holst, Jens Juul & Gromada, J., 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 2, p. E199-206

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Secretion of incretin hormones (GIP and GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes.

    Nauck, M. A., El-Ouaghlidi, A., Gabrys, B., Hücking, K., Holst, Jens Juul, Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Meier, J. J., 2004, In: Regulatory Peptides. 122, 3, p. 209-17 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Secretion, degradation, and elimination of glucagon-like peptide 1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjects.

    Meier, J. J., Nauck, M. A., Kranz, D., Holst, Jens Juul, Deacon, Carolyn F., Gaeckler, D., Schmidt, W. E. & Gallwitz, B., 2004, In: Diabetes. 53, 3, p. 654-62 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Similar gastric emptying but greater gastric secretion and GIP release after the ingestion of peptide hydrolysates in man

    Calbet, J. A. L. & Holst, Jens Juul, 2004, In: Eur J Nutrition. 43, p. 127-139

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Stimulation of insulin secretion by intravenous bolus injection and continuous infusion of gastric inhibitory polypeptide in patients with type 2 diabetes and healthy control subjects.

    Meier, J. J., Gallwitz, B., Kask, B., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2004, In: Diabetes. 53 Suppl 3, p. S220-4

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation following and 80% jejunoileal resection in neonatal pigs

    Bartholome, A. L., Albin, D. M., Baker, D. H., Holst, Jens Juul & Tappenden, K. A., 2004, In: J Parenter Enteral Nutr. 28, p. 210-223

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The incretin approach for diabetes treatment: modulation of islet hormone release by GLP-1 agonism.

    Holst, Jens Juul & Ørskov, Cathrine, 2004, In: Diabetes. 53 Suppl 3, p. S197-204

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The ¤use of glycaemic index tables to predict glycaemic index of composite breakfast meals

    Flint, A., Møller, B. K., Raben, Anne, Pedersen, D., Tetens, I., Holst, Jens Juul & Astrup, A., 2004, In: British Journal of Nutrition. 91, 6, p. 979-989 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Treatment of type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors.

    Holst, Jens Juul, 2004, In: Expert Opinion on Emerging Drugs. 9, 1, p. 155-66 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Antihyperglycemic effects of stevioside in type 2 diabetic subjects

    Gregersen, S., Jeppesen, P. B., Holst, Jens Juul & Hermansen, K., Jan 2004, In: Metabolism. 53, 1, p. 73-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Cholecystokinin inhibits gastrin secretion independently of paracrine somatostatin secretion in the pig

    Schmidt, P. T., Hansen, L., Hilsted, Linda & Holst, Jens Juul, Mar 2004, In: Scandinavian Journal of Gastroenterology. 39, 3, p. 217-21 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Incretins, insulin secretion and Type 2 diabetes mellitus

    Vilsbøll, T. & Holst, Jens Juul, Mar 2004, In: Diabetologia. 47, 3, p. 357-66 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Intravenous glucagon-like peptide 1 normalizes blood glucose after major surgery in patients with type 2 diabetes

    Meier, J. J., Weyhe, D., Michaely, M., Senkal, M., Zumtobel, V., Nauck, M. A., Holst, Jens Juul, Schmidt, W. E. & Gallwitz, B., Mar 2004, In: New Horizons (Baltimore). 32, 3, p. 848-51 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Prandial subcutaneous injections of glucagon-like peptide-1 cause weight loss in obese human subjects

    Näslund, E., King, N., Mansten, S., Adner, N., Holst, Jens Juul, Gutniak, M. & Hellström, P. M., Mar 2004, In: The British Journal of Nutrition. 91, 3, p. 439-46 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Gastric inhibitory polypeptide does not inhibit gastric emptying in humans

    Meier, J. J., Goetze, O., Anstipp, J., Hagemann, D., Holst, Jens Juul, Schmidt, W. E., Gallwitz, B. & Nauck, M. A., Apr 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 286, 4, p. E621-5

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Glucagon-like peptide-2 inhibits antral emptying in man, but is not as potent as glucagon-like peptide-1

    Nagell, C. F., Wettergren, A., Pedersen, J. F., Mortensen, D. & Holst, Jens Juul, Apr 2004, In: Scandinavian Journal of Gastroenterology. 39, 4, p. 353-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Blood glucose control in healthy subject and patients receiving intravenous glucose infusion or total parenteral nutrition using glucagon-like peptide 1

    Nauck, M. A., Walberg, J., Vethacke, A., El-Ouaghlidi, A., Senkal, M., Holst, Jens Juul, Gallwitz, B., Gallwitz, J. B., Schmidt, W. E. & Schmiegel, W., 15 Apr 2004, In: Regulatory Peptides. 118, 1-2, p. 89-97 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Glucagon-like peptide-1 secretion is influenced by perfusate glucose concentration and by a feedback mechanism involving somatostatin in isolated perfused porcine ileum

    Hansen, L., Hartmann, Bolette, Mineo, H. & Holst, Jens Juul, 15 Apr 2004, In: Regulatory Peptides. 118, 1-2, p. 11-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors

    Hansotia, T., Baggio, L. L., Delmeire, D., Hinke, S. A., Yamada, Y., Tsukiyama, K., Seino, Y., Holst, Jens Juul, Schuit, F. & Drucker, D. J., May 2004, In: Diabetes. 53, 5, p. 1326-35 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance

    Rask, E., Olsson, T., Söderberg, S., Holst Jj, J. J., Tura, A., Pacini, G., Ahrén, B. & Holst, Jens Juul, May 2004, In: Metabolism. 53, 5, p. 624-31 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Gastric emptying, gastric secretion and enterogastrone response after administration of milk proteins or their peptide hydrolysates in humans

    Calbet, J. A. L. & Holst, Jens Juul, Jun 2004, In: European Journal of Nutrition. 43, 3, p. 127-39 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Onset of small intestinal atrophy is associated with reduced intestinal blood flow in TPN-fed neonatal piglets

    Niinikoski, H., Stoll, B., Guan, X., Kansagra, K., Lambert, B. D., Stephens, J., Hartmann, Bolette, Holst, Jens Juul & Burrin, D. G., Jun 2004, In: Journal of Nutrition. 134, 6, p. 1467-74 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Glucagon-like peptide 2 (GLP-2) accelerates the growth of colonic neoplasms in mice

    Thulesen, J., Hartmann, Bolette, Hare, K. J., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Aug 2004, In: Gut. 53, 8, p. 1145-1150 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal piglets

    Bartholome, A. L., Albin, D. M., Baker, D. H., Holst, Jens Juul & Tappenden, K. A., 5 Aug 2004, In: Journal of Parenteral and Enteral Nutrition. 28, 4, p. 210-22; discussion 222-3

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    GLP-2 levels in infants with intestinal dysfunction

    Sigalet, D. L., Martin, G., Meddings, J., Hartman, B. & Holst, Jens Juul, Sep 2004, In: Pediatric Research. 56, 3, p. 371-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Plasma GLP-2 levels and intestinal markers in the juvenile pig during intestinal adaptation: effects of different diet regimens

    Paris, M. C., Fuller, P. J., Carstensen, Bendix, Nagy, E., Taylor, R. G., Sourial, M., Holst, Jens Juul, Hartmann, Bolette & Binesm, J. E., Oct 2004, In: Digestive Diseases and Sciences. 49, 10, p. 1688-95 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Glycemia and insulinemia in healthy subjects after lactose-equivalent meals of milk and other food proteins: the role of plasma amino acids and incretins

    Nilsson, M., Stenberg, M., Frid, A. H., Holst, Jens Juul & Björck, I. M. E., Nov 2004, In: Uden navn. 80, 5, p. 1246-53 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Neural regulation of glucagon-like peptide-1 secretion in pigs

    Hansen, L., Lampert, S., Mineo, H. & Holst, Jens Juul, Nov 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 5, p. E939-47

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2005
  40. Published

    Alpha-Glucosidase inhibition (Acarbose) fails to enhance secretion of glucagons-like peptide 1(7-36 amide) and to delay gastric emptying in type 2 diabetic patients

    Hücking, K., Kostic, Z., Pox, C., Ritzel, R., Holst, Jens Juul, Schmiegel, W. & Nauck, M. A., 2005, In: Diabet. Med.. 22, p. 470-476

    Research output: Contribution to journalJournal articleResearch

  41. Published

    Defective glucose and lipid metabolism in human immunodeficiency virus-infected patients with lipodystrophy involve liver, muscle tissue and pancreatic beta-cells.

    Haugaard, S. B., Andersen, Ove, Dela, Flemming, Holst, Jens Juul, Storgaard, H., Fenger, M., Iversen, J., Madsbad, Sten, Haugaard, S. B., Andersen, Ove, Dela, F., Holst, J. J., Storgaard, H., Fenger, M., Iversen, J. & Madsbad, Sten, 2005, In: European Journal of Endocrinology. 152, 1, p. 103-112 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Differential postprandial lipoprotein responses in type 2 diabetic men with and without clinical evidence of a former myocardial infarction.

    Carstensen, M., Thomsen, C., Gotzsche, O., Holst, Jens Juul, Schrezenmeir, J. & Hermansen, K., 2005, In: The review of diabetic studies : RDS. 1, 4, p. 175-84 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Dipeptidyl peptidase IV inhibitors: a promising new therapeutic approach for the management of type 2 diabetes.

    Deacon, Carolyn F. & Holst, Jens Juul, 2005, In: International Journal of Biochemistry & Cell Biology. 38, 5-6, p. 831-44 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility.

    Miki, T., Minami, K., Shinozaki, H., Matsumura, K., Saraya, A., Ikeda, H., Yamada, Y., Holst, Jens Juul & Seino, S., 2005, In: Diabetes. 54, 4, p. 1056-63 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Effect of whey on blood glucose and insulin responses to composite breakfast and lunch meals in type 2 diabetic subjects.

    Frid, A. H., Nilsson, M., Holst, Jens Juul & Björck, I. M. E., 2005, In: American Journal of Clinical Nutrition. 82, 1, p. 69-75 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Enhanced glucagon-like peptide- 1 (GLP-1) response to oral glucose in glucose intolerant HIV-infected patients on antiretroviral therapy

    Andersen, O., Haugaard, S. B., Holst, Jens Juul, Deacon, Carolyn F., Iversen, J., Andersen, U. B., Nielsen, J. O. & Madsbad, S., 2005, In: HIV Medicine. 6, p. 91-98

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Enteral feeding without pancreatic stimulation.

    Kaushik, N., Pietraszewski, M., Holst, Jens Juul & O'Keefe, S. J. D., 2005, In: Pancreas. 31, 4, p. 353-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Erythromycin antagonises the deceleration of gastric emptying by glucagon-like peptide-1 (GLP)-1 and unmasks its insulinotropic effect in healthy subjects

    Meier, J. J., Kemmeries, G., Holst, Jens Juul & Nauck, M. A., 2005, In: Diabetes. 54, p. 2212-2218

    Research output: Contribution to journalJournal articleResearch

  49. Published

    Evidence for an endocrine pancreatico-gastric axis: The role of pancreatic polypeptide in gastric emptying and short term metabolic control

    Schmidt, P. T., Näslund, E., Grybäck, P., Jacobsson, H., Holst, Jens Juul, Hilsted, L. & Hellström, P. M., 2005, In: J. Clin. Endocrinol. Metab.. 90, p. 5241-5246

    Research output: Contribution to journalJournal articleResearch

  50. Published

    Evidence of an association between the Arg72 allele of the peptide YY and increased risk of type 2 diabetes

    Torekov, Signe Sørensen, Larsen, L. H., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Holst, Jens Juul, Madsen, O. D., Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Diabetes. 54, 7, p. 2261-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Evidence of an association between the Arg72-allele of the peptide YY (PYY) and increased risk of type 2 diabetes

    Torekov, S. S., Larsen, L. H., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Holst, Jens Juul, Madsen, O. D., Hansen, T. & Pedersen, O., 2005, In: Diabetes. 54, p. 2261-2265

    Research output: Contribution to journalJournal articleResearch

  52. Published

    Exenatide augments first and second phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes

    Fehse, F., Trautmann, M., Holst, Jens Juul, Halseth, A. E., Nanyakkara, N., Nielsen, L., Fineman, M. S. D., Kim, D. D. & Nauck, M. A., 2005, In: J. Clin. Endocrinol. Metab.. 90, p. 5991-5997

    Research output: Contribution to journalJournal articleResearch

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