Cathrine Ørskov
Head of Department
Endocrinology and Metabolism
Blegdamsvej 3, Building: 12-4-20
2200 København N
- 2004
- Published
The incretin approach for diabetes treatment: modulation of islet hormone release by GLP-1 agonism.
Holst, Jens Juul & Ørskov, Cathrine, 2004, In: Diabetes. 53 Suppl 3, p. S197-204Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Typical Danish Caucasian type 2 diabetic patients do not commonly carry germ line mutations in GIP and GLP-1 encoding regions of the proGIP and proglucagon genes
Ørskov, Cathrine, Hjorth, S. A., Jensen, A. D. & Vilsbøll, T., 2004, In: Regul. Pept.. 119, p. 151-154Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 2 (GLP-2) accelerates the growth of colonic neoplasms in mice
Thulesen, J., Hartmann, Bolette, Hare, K. J., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Aug 2004, In: Gut. 53, 8, p. 1145-1150 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptors.
Ørskov, Cathrine, Hartmann, B., Poulsen, Steen Seier, Thulesen, J., Hare, K. J. & Holst, Jens Juul, 2005, In: Regulatory Peptides. 124, 1-3, p. 105-12 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MEK kinase 1 activity is required for definitive erythropoiesis in the mouse fetal liver.
Bonnesen, B., Ørskov, Cathrine, Rasmussen, S., Holst, Peter Johannes, Christensen, Jan Pravsgaard, Eriksen, K. W., Qvortrup, Klaus, Odum, N. & Labuda, T., 2005, In: Blood. 106, 10, p. 3396-404 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Inhibitory effect of GLP-1 on gastric motility persists after vagal deafferentation in pigs.
Nagell, C. F., Wettergren, A., Ørskov, Cathrine & Holst, Jens Juul, 2006, In: Scandinavian Journal of Gastroenterology. 41, 6, p. 667-72 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes
Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, A. C., Jansen-Olesen, I., Chiarelli, F., Holst, J. J., Hougaard, P. P., Porksen, S., Holl, R., Beaufort, C. D., Gammeltoft, S., Rorsman, P., Mortensen, H. B., Hansen, L., Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, C., Jansen-Olesen, I. & 11 others, , 2007, In: European Journal of Endocrinology. 156, 6, p. 663-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects
Pedersen, N. B., Hjøllund, K. R., Johnsen, A. H., Ørskov, Cathrine, Rosenkilde, Mette, Hartmann, B. & Holst, Jens Juul, 2007, In: Regulatory Peptides. 146, 1-3, p. 310-320 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes
Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, Cathrine, Jansen-Olesen, I., Chiarelli, F., Holst, Jens Juul, Hougaard, P., Pörksen, S., Holl, R., de Beaufort, C., Gammeltoft, S., Rorsman, P., Mortensen, H. B. & Hansen, L., Jun 2007, In: European Journal of Endocrinology. Supplement. 156, 6, p. 663-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meal-stimulated glucagon release is associated with postprandial blood glucose level and does not interfere with glycemic control in children and adolescents with new-onset type 1 diabetes
Pörksen, S., Nielsen, L. B., Kaas, A., Kocova, M., Chiarelli, F., Ørskov, Cathrine, Holst, Jens Juul, Ploug, K. B., Hougaard, P., Hansen, L. & Mortensen, H. B., Aug 2007, In: The Journal of clinical endocrinology and metabolism. 92, 8, p. 2910-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The alpha cell expresses glucagon-like peptide-2 receptors and glucagon-like peptide-2 stimulates glucagon secretion from the rat pancreas
de Heer, J., Pedersen, J., Ørskov, Cathrine & Holst, Jens Juul, Oct 2007, In: Diabetologia. 50, 10, p. 2135-42 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Targets and tactics: the relative importance of HbA, fasting and postprandial plasma glucose levels to glycaemic control in type 2 diabetes
Woo, V., Shestakova, M. V., Ørskov, Cathrine & Ceriello, A., Dec 2008, In: International Journal of Clinical Practice. 62, 12, p. 1935-42 8 p.Research output: Contribution to journal › Review › Research › peer-review
- 2010
- Published
Quality of the transgene-specific CD8+ T cell response induced by adenoviral vector immunization is critically influenced by virus dose and route of vaccination
Holst, Peter Johannes, Ørskov, Cathrine, Thomsen, Allan Randrup & Christensen, Jan Pravsgaard, 2010, In: Journal of Immunology. 184, 8, p. 4431-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
JNK1, but not JNK2, is required in two mechanistically distinct models of inflammatory arthritis
Denninger, K., Rasmussen, S. B., Larsen, J. M., Ørskov, Cathrine, Poulsen, Steen Seier, Sørensen, P., Christensen, Jan Pravsgaard, Illges, H., Ødum, Niels & Labuda, T., 2011, In: American Journal of Pathology. 179, 4, p. 1884-93 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Metformin stimulates FGF21 expression in primary hepatocytes
Nygaard, E. B., Vienberg, S. G., Ørskov, Cathrine, Hansen, Harald S. & Andersen, B., 2012, In: Experimental Diabetes Research. 2012, p. 465282 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
IFNγ and perforin cooperate to control infection and prevent fatal pathology during persistent gammaherpesvirus infection in mice
Bartholdy, C., Høgh-Petersen, M., Storm, P., Holst, Peter Johannes, Ørskov, Cathrine, Christensen, Jan Pravsgaard & Thomsen, Allan Randrup, 31 Mar 2014, In: Scandinavian Journal of Immunology. 79, 6, p. 395-403 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
GLP-1 receptor localization in monkey and human tissue: novel distribution revealed with extensively validated monoclonal antibody
Pyke, C., Heller, R. S., Kirk, R. K., Ørskov, Cathrine, Reedtz-Runge, S., Kaastrup, P., Hvelplund, A., Bardram, L., Calatayud, D. & Knudsen, L. B., Apr 2014, In: Endocrinology. 155, 4, p. 1280-90 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
The glucagon-like peptide 2 receptor is expressed in enteric neurons and not in the epithelium of the intestine
Pedersen, Jens, B. Pedersen, N., Brix, S. W., Grunddal, Kaare Villum, Rosenkilde, Mette, Hartmann, Bolette, Ørskov, Cathrine, Poulsen, Steen Seier & Holst, Jens Juul, May 2015, In: Peptides. 67, p. 20-28 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
Structural insight into antibody-mediated antagonism of the Glucagon-like peptide-1 Receptor
Hennen, S., Kodra, J. T., Soroka, V., Krogh, B. O., Wu, X., Kaastrup, P., Ørskov, Cathrine, Rønn, S. G., Schluckebier, G., Barbateskovic, S., Gandhi, P. S. & Reedtz-Runge, S., 2016, In: Scientific Reports. 6, 11 p., 26236.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis
Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørskov, Cathrine, Kissow, Hannelouise, Poulsen, Steen Seier, Vilstrup, H., Prehn, C., Adamski, J., Jepsen, Sara Lind, Hartmann, Bolette, Dal, Jenna Elizabeth Hunt, Charron, M. J., Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 1, p. E93-E103Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fasting decreases plasma FGF21 in obese subjects and the expression of FGF21 receptors in adipose tissue in both lean and obese subjects
Nygaard, E. B., Ørskov, Cathrine, Almdal, Thomas Peter, drb459, drb459 & Andersen, B., 2018, In: Journal of Endocrinology. 239, 1, p. 73-80Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo testing of novel vaccine prototypes against Actinobacillus pleuropneumoniae
Antenucci, F., Fougeroux, Cyrielle Elyette, Deeney, A., Ørskov, Cathrine, Rycroft, A., Holst, Peter Johannes & Bojesen, Anders Miki, Jan 2018, In: Veterinary Research. 49, 1, 11 p., 4.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue
Lundh, M., Petersen, P. S., Isidor, Marie Sophie, Kazoka-Sørensen, D. N., Plucinska, Kaja, Shamsi, F., Ørskov, Cathrine, Tozzi, M., Brown, E. L., Andersen, E., Ma, Tao, Müller, U. A., Barrès, Romain, Kristiansen, V. B., Gerhart-Hines, Zach, Tseng, Y. & Emanuelli, Brice, 2019, In: EMBO Reports. 20, 8, e48216.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut-derived glucagon in man: [Meeting Abstract]
Baekdal, M., Lund, A., Albrechtsen, Nicolai Jacob Wewer, Egholk, J., Jorsal, T., Black-Juel, C. T., Dal, Jenna Elizabeth Hunt, Galsgaard, Katrine Douglas, Rigbolt, K., Palnaes, C., Ørskov, Cathrine, Poulsen, Steen Seier, Holst, Jens Juul, Villsboll, T. & Knop, Filip Krag, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S231-S231 472.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Investigating Intestinal Glucagon after Roux-en-Y Gastric Bypass Surgery
Jorsal, T., Wewer Albrechtsen, N. J., Christensen, M. M., Mortensen, B., Wandall, E., Langholz, E., Friis, S., Worm, D., Ørskov, C., Støving, R. K., Andries, A., Juhl, C. B., Sørensen, F., Forman, J. L., Falkenhahn, M., Musholt, P. B., Theis, S., Larsen, P. J., Holst, J. J., Vrang, N. & 3 others, , 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 12, p. 6403–6416 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 137086045
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In vivo testing of novel vaccine prototypes against Actinobacillus pleuropneumoniae
Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis
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No direct effect of SGLT2 activity on glucagon secretion
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