Thomas Jespersen
Professor
Physiology of circulation, kidney and lung
Blegdamsvej 3, Building: 12-5-08
2200 København N
Denmark
Member of:
- 2011
- Published
Characterization of cardiac repolarization in the Göttingen minipig
Laursen, M., Olesen, Søren-Peter, Grunnet, Morten, Mow, T., Jespersen, T. & Jespersen, Thomas, 2011, In: Journal of Pharmacological and Toxicological Methods. 63, 2, p. 186-95 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of the Effects of a Transient Outward Potassium Channel Activator on Currents Recorded from Atrial and Ventricular Cardiomyocytes.
Callø, Kirstine, Nof, E., Jespersen, Thomas, Di Diego, J. M., Chlus, N., Olesen, Søren-Peter, Antzelevitch, C. & Cordeiro, J. M., 2011, In: Journal of Cardiovascular Electrophysiology. 22, 9, p. 1057-1066 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects on atrial fibrillation in aged hypertensive rats by Ca(2+)-activated K(+) channel inhibition
Diness, Jonas Goldin, Skibsbye, L., Jespersen, Thomas, Bartels, Emil Daniel, Sørensen, U. S., Hansen, R. S. & Grunnet, Morten, 2011, In: Hypertension. 57, 6, p. 1129-35 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutations in sodium channel {beta}-subunit SCN3B are associated with early-onset lone atrial fibrillation
Olesen, M. S., Jespersen, Thomas, Nielsen, J. B., Liang, B., Møller, D. V., Hedley, P., Christiansen, M., Varro, A., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole & Svendsen, Jesper Hastrup, 2011, In: Cardiovascular Research. 89, 4, p. 786-793 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation and physiological function of Na(v) 1.5 and KCNQ1 channels
Jespersen, Thomas, 2011, In: Acta Physiologica (Print). 202 Suppl 683, p. 1-26 26 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening of KCNN3 in patients with early-onset lone atrial fibrillation
Olesen, M. S., Jabbari, J., Holst, A. G., Nielsen, J. B., Steinbrüchel, D. A., Jespersen, T., Haunsø, Stig, Svendsen, Jesper Hastrup & Jespersen, Thomas, 2011, In: Europace. 13, 7, p. 963-967 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Novel Nonsense Variant in Nav1.5 Cofactor MOG1 Eliminates Its Sodium Current Increasing Effect and May Increase the Risk of Arrhythmias
Olesen, M. S., Jensen, N. F., Holst, A. G., Nielsen, J. B., Tfelt-Hansen, Jacob, Jespersen, Thomas, Sajadieh, Ahmad, Haunsø, Stig, Lund, J. T., Callø, Kirstine, Schmitt, Nicole & Svendsen, Jesper Hastrup, 26 May 2011, In: Canadian Journal of Cardiology. 27, 4, p. 523.e17-23Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
AMP-activated protein kinase downregulates Kv7.1 cell surface expression
Andersen, M. N., Krzystanek, K., Jespersen, Thomas, Olesen, Søren-Peter & Rasmussen, Hanne Borger, 2012, In: Traffic. 13, 1, p. 143-56 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Attenuated ventricular β-adrenergic response and reduced repolarization reserve in a rabbit model of chronic heart failure
Nissen, J. D., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Diness, Jonas Goldin, Diness, T. G., Jespersen, Thomas & Grunnet, Morten, 2012, In: Journal of Cardiovascular Pharmacology. 59, 2, p. 142-150 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels
Krzystanek, K., Rasmussen, Hanne Borger, Grunnet, Morten, Staub, O., Olesen, Søren-Peter, Abriel, H. & Jespersen, Thomas, 2012, In: Heart Rhythm. 9, 3, p. 440-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High Prevalence of Long QT Syndrome Associated SCN5A Variants in Patients with Early-Onset Lone Atrial Fibrillation
Olesen, M. S., Yuan, L., Liang, B., Holst, A. G., Nielsen, N., Nielsen, J. B., Hedley, P. L., Christiansen, M., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole, Jespersen, Thomas & Svendsen, Jesper Hastrup, 2012, In: Circulation: Cardiovascular Genetics. 5, 4, p. 450-459 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts
Laursen, M., Grunnet, Morten, Olesen, Søren-Peter, Jespersen, Thomas & Mow, T., 2012, In: Journal of Pharmacological and Toxicological Methods. 64, 2, p. 134-44 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiac Arrhythmia - new considerations: The Cardiac Ion Channels
Jespersen, Thomas, 29 Feb 2012, Cardiac Arrhythmias - new considerations. Breijo-Marquez, F. R. (ed.). Croatia: InTech, p. 45-72 29 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Functionally Selective AT(1) Receptor Activation Reduces Ischemia Reperfusion Injury
Hostrup, A., Christensen, G. L., Bentzen, Bo Hjorth, Liang, B., Aplin, M., Grunnet, Morten, Hansen, J. L. & Jespersen, Thomas, 30 Jul 2012, In: Cellular Physiology and Biochemistry. 30, 3, p. 642-652 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Double mutation at the putative protein kinase C phosphorylation sites Thr151 plus Thr323 in the mouse leukotrieneD4 receptor eliminates homologous desensitization
Jørgensen, S. T., Eriksen, H. N., Dausell, J., Jespersen, Thomas, Lambert, Ian Henry & Hoffmann, E. K., 2013, In: Cellular Physiology and Biochemistry. 31, 2-3, p. 366-378 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology
Wang, X., Liang, B., Skibsbye, L., Olesen, Søren-Peter, Grunnet, Morten & Jespersen, Thomas, Aug 2013, In: Journal of Cardiovascular Pharmacology. 62, 2, p. 192-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of CAV3 in long-QT syndrome: clinical and functional assessment of a caveolin-3/Kv11.1 double heterozygote versus caveolin-3 single heterozygote
Hedley, P. L., Kanters, Jørgen K., Dembic, M., Jespersen, Thomas, Skibsbye, L., Aidt, F. H., Eschen, O., Graff, C., Behr, E. R., Schlamowitz, S., Corfield, V., McKenna, W. J. & Christiansen, M., Oct 2013, In: Circulation: Cardiovascular Genetics. 6, 5, p. 452-61 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein
Andersen, M. N., Krzystanek, K., Petersen, F., Bomholtz, Sofia Hammami, Olesen, Søren-Peter, Abriel, H., Jespersen, Thomas & Rasmussen, Hanne Borger, 8 Nov 2013, In: The Journal of Biological Chemistry. 288, 52, p. 36841-54 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization
Liang, B., Nissen, J. D., Laursen, M., Wang, X., Skibsbye, L., Hearing, M. C., Andersen, M. N., Rasmussen, Hanne Borger, Wickman, K., Grunnet, Morten, Olesen, Søren-Peter & Jespersen, Thomas, 1 Jan 2014, In: Cardiovascular Research. 101, 1, p. 175-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant.
Yuan, L., Koivumäki, J., Liang, B., Lorentzen, Lasse Gøbel, Tang, C., Andersen, M., Svendsen, J., Tfelt-Hansen, Jacob, Maleckar, M., Schmitt, Nicole, Olesen, M. & Jespersen, Thomas, Feb 2014, In: American journal of physiology. Heart and circulatory physiology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada Syndrome mutant
Yuan, L., Koivumaki, J., Liang, B., Lorentzen, L. G., Tang, C., Andersen, M. N., Svendsen, Jesper Hastrup, Tfelt-Hansen, J., Maleckar, M., Schmitt, Nicole, Olesen, Morten Steen Salling & Jespersen, Thomas, 21 Feb 2014, In: American Journal of Physiology: Heart and Circulatory Physiology. 306, 8, p. H1204-12Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Flecainide provocation reveals concealed brugada syndrome in a long QT syndrome family with a novel L1786Q mutation in SCN5A. SCN5A mutations associated with overlap phenotype of long QT syndrome type 3 and Brugada syndrome.
Kanters, Jørgen K., Yuan, L., Hedley, P. L., Stoevring, B., Jons, C., Bloch Thomsen, P. E., Grunnet, Morten, Christiansen, M. & Jespersen, Thomas, 6 Mar 2014, In: Circulation Journal. 78, 5, p. 1136-43 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarisation in human atria.
Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-167 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria
Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, 1 Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-67 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses
Haugaard, M. M., Pehrson, S., Carstensen, Helena, Madsen, M. F., Hesselkilde, E. Z., Præstegaard, K. F., Diness, J. G., Grunnet, M., Jespersen, Thomas & Buhl, Rikke, 2015, In: Journal of Veterinary Internal Medicine. 29, 1, p. 339-347 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8117
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Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
346
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Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
326
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Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia
Research output: Contribution to journal › Journal article › Research › peer-review
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