Thomas Jespersen

Thomas Jespersen

Professor

Member of:


    1. 2011
    2. Published

      Characterization of cardiac repolarization in the Göttingen minipig

      Laursen, M., Olesen, Søren-Peter, Grunnet, Morten, Mow, T., Jespersen, T. & Jespersen, Thomas, 2011, In: Journal of Pharmacological and Toxicological Methods. 63, 2, p. 186-95 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Comparison of the Effects of a Transient Outward Potassium Channel Activator on Currents Recorded from Atrial and Ventricular Cardiomyocytes.

      Callø, Kirstine, Nof, E., Jespersen, Thomas, Di Diego, J. M., Chlus, N., Olesen, Søren-Peter, Antzelevitch, C. & Cordeiro, J. M., 2011, In: Journal of Cardiovascular Electrophysiology. 22, 9, p. 1057-1066 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Effects on atrial fibrillation in aged hypertensive rats by Ca(2+)-activated K(+) channel inhibition

      Diness, Jonas Goldin, Skibsbye, L., Jespersen, Thomas, Bartels, Emil Daniel, Sørensen, U. S., Hansen, R. S. & Grunnet, Morten, 2011, In: Hypertension. 57, 6, p. 1129-35 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Mutations in sodium channel {beta}-subunit SCN3B are associated with early-onset lone atrial fibrillation

      Olesen, M. S., Jespersen, Thomas, Nielsen, J. B., Liang, B., Møller, D. V., Hedley, P., Christiansen, M., Varro, A., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole & Svendsen, Jesper Hastrup, 2011, In: Cardiovascular Research. 89, 4, p. 786-793 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Regulation and physiological function of Na(v) 1.5 and KCNQ1 channels

      Jespersen, Thomas, 2011, In: Acta Physiologica (Print). 202 Suppl 683, p. 1-26 26 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Screening of KCNN3 in patients with early-onset lone atrial fibrillation

      Olesen, M. S., Jabbari, J., Holst, A. G., Nielsen, J. B., Steinbrüchel, D. A., Jespersen, T., Haunsø, Stig, Svendsen, Jesper Hastrup & Jespersen, Thomas, 2011, In: Europace. 13, 7, p. 963-967 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      A Novel Nonsense Variant in Nav1.5 Cofactor MOG1 Eliminates Its Sodium Current Increasing Effect and May Increase the Risk of Arrhythmias

      Olesen, M. S., Jensen, N. F., Holst, A. G., Nielsen, J. B., Tfelt-Hansen, Jacob, Jespersen, Thomas, Sajadieh, Ahmad, Haunsø, Stig, Lund, J. T., Callø, Kirstine, Schmitt, Nicole & Svendsen, Jesper Hastrup, 26 May 2011, In: Canadian Journal of Cardiology. 27, 4, p. 523.e17-23

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. 2012
    10. Published

      AMP-activated protein kinase downregulates Kv7.1 cell surface expression

      Andersen, M. N., Krzystanek, K., Jespersen, Thomas, Olesen, Søren-Peter & Rasmussen, Hanne Borger, 2012, In: Traffic. 13, 1, p. 143-56 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Attenuated ventricular β-adrenergic response and reduced repolarization reserve in a rabbit model of chronic heart failure

      Nissen, J. D., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Diness, Jonas Goldin, Diness, T. G., Jespersen, Thomas & Grunnet, Morten, 2012, In: Journal of Cardiovascular Pharmacology. 59, 2, p. 142-150 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels

      Krzystanek, K., Rasmussen, Hanne Borger, Grunnet, Morten, Staub, O., Olesen, Søren-Peter, Abriel, H. & Jespersen, Thomas, 2012, In: Heart Rhythm. 9, 3, p. 440-8 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      High Prevalence of Long QT Syndrome Associated SCN5A Variants in Patients with Early-Onset Lone Atrial Fibrillation

      Olesen, M. S., Yuan, L., Liang, B., Holst, A. G., Nielsen, N., Nielsen, J. B., Hedley, P. L., Christiansen, M., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole, Jespersen, Thomas & Svendsen, Jesper Hastrup, 2012, In: Circulation: Cardiovascular Genetics. 5, 4, p. 450-459 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts

      Laursen, M., Grunnet, Morten, Olesen, Søren-Peter, Jespersen, Thomas & Mow, T., 2012, In: Journal of Pharmacological and Toxicological Methods. 64, 2, p. 134-44 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Cardiac Arrhythmia - new considerations: The Cardiac Ion Channels

      Jespersen, Thomas, 29 Feb 2012, Cardiac Arrhythmias - new considerations. Breijo-Marquez, F. R. (ed.). Croatia: InTech, p. 45-72 29 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    16. Published

      Functionally Selective AT(1) Receptor Activation Reduces Ischemia Reperfusion Injury

      Hostrup, A., Christensen, G. L., Bentzen, Bo Hjorth, Liang, B., Aplin, M., Grunnet, Morten, Hansen, J. L. & Jespersen, Thomas, 30 Jul 2012, In: Cellular Physiology and Biochemistry. 30, 3, p. 642-652 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. 2013
    18. Published

      Double mutation at the putative protein kinase C phosphorylation sites Thr151 plus Thr323 in the mouse leukotrieneD4 receptor eliminates homologous desensitization

      Jørgensen, S. T., Eriksen, H. N., Dausell, J., Jespersen, Thomas, Lambert, Ian Henry & Hoffmann, E. K., 2013, In: Cellular Physiology and Biochemistry. 31, 2-3, p. 366-378 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology

      Wang, X., Liang, B., Skibsbye, L., Olesen, Søren-Peter, Grunnet, Morten & Jespersen, Thomas, Aug 2013, In: Journal of Cardiovascular Pharmacology. 62, 2, p. 192-8 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      The role of CAV3 in long-QT syndrome: clinical and functional assessment of a caveolin-3/Kv11.1 double heterozygote versus caveolin-3 single heterozygote

      Hedley, P. L., Kanters, Jørgen K., Dembic, M., Jespersen, Thomas, Skibsbye, L., Aidt, F. H., Eschen, O., Graff, C., Behr, E. R., Schlamowitz, S., Corfield, V., McKenna, W. J. & Christiansen, M., Oct 2013, In: Circulation: Cardiovascular Genetics. 6, 5, p. 452-61 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein

      Andersen, M. N., Krzystanek, K., Petersen, F., Bomholtz, Sofia Hammami, Olesen, Søren-Peter, Abriel, H., Jespersen, Thomas & Rasmussen, Hanne Borger, 8 Nov 2013, In: The Journal of Biological Chemistry. 288, 52, p. 36841-54 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. 2014
    23. Published

      G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization

      Liang, B., Nissen, J. D., Laursen, M., Wang, X., Skibsbye, L., Hearing, M. C., Andersen, M. N., Rasmussen, Hanne Borger, Wickman, K., Grunnet, Morten, Olesen, Søren-Peter & Jespersen, Thomas, 1 Jan 2014, In: Cardiovascular Research. 101, 1, p. 175-84 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant.

      Yuan, L., Koivumäki, J., Liang, B., Lorentzen, Lasse Gøbel, Tang, C., Andersen, M., Svendsen, J., Tfelt-Hansen, Jacob, Maleckar, M., Schmitt, Nicole, Olesen, M. & Jespersen, Thomas, Feb 2014, In: American journal of physiology. Heart and circulatory physiology.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada Syndrome mutant

      Yuan, L., Koivumaki, J., Liang, B., Lorentzen, L. G., Tang, C., Andersen, M. N., Svendsen, Jesper Hastrup, Tfelt-Hansen, J., Maleckar, M., Schmitt, Nicole, Olesen, Morten Steen Salling & Jespersen, Thomas, 21 Feb 2014, In: American Journal of Physiology: Heart and Circulatory Physiology. 306, 8, p. H1204-12

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Flecainide provocation reveals concealed brugada syndrome in a long QT syndrome family with a novel L1786Q mutation in SCN5A. SCN5A mutations associated with overlap phenotype of long QT syndrome type 3 and Brugada syndrome.

      Kanters, Jørgen K., Yuan, L., Hedley, P. L., Stoevring, B., Jons, C., Bloch Thomsen, P. E., Grunnet, Morten, Christiansen, M. & Jespersen, Thomas, 6 Mar 2014, In: Circulation Journal. 78, 5, p. 1136-43 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarisation in human atria.

      Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-167 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria

      Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, 1 Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-67 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. 2015
    30. Published

      Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses

      Haugaard, M. M., Pehrson, S., Carstensen, Helena, Madsen, M. F., Hesselkilde, E. Z., Præstegaard, K. F., Diness, J. G., Grunnet, M., Jespersen, Thomas & Buhl, Rikke, 2015, In: Journal of Veterinary Internal Medicine. 29, 1, p. 339-347 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 8117