Jens Juul Holst

Jens Juul Holst

Professor


  1. 2009
  2. Published

    Incretin hormones and diabetes mellitus

    Vilsbøll, Tina, Knop, Filip Krag, Deacon, Carolyn F. & Holst, Jens Juul, 2009, Therapeutic Strategies in Diabetes. Stehouwer, C. D. A. & Schaper, N. (eds.). Oxford: Clinical Publishing, p. 99-114

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  3. Published

    Incretin-based therapy of type 2 diabetes mellitus

    Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2009, In: Current Protein and Peptide Science. 10, 1, p. 46-55 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Inhibition of neutral endopeptidase 24.11 does not potentiate the improvement in glycemic control obtained with dipeptidyl peptidase-4 inhibition in diabetic Goto-Kakizaki rats

    Simonsen, L., Pilgaard, S., Carr, R. D., Kanstrup, A. B., Holst, Jens Juul & Deacon, Carolyn F., 2009, In: Hormone and Metabolic Research. 41, 11, p. 851-3 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide (GIP) in patients with type 2 diabetes

    Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-608

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Kirurgisk behandling af type 2-diabetes

    Olesen, S. C., Hansen, D. L., Almdal, Thomas Peter, Bendtsen, Flemming, Nordgaard, I., Hvolris, L. E., Holst, Jens Juul, Naver, L. & Madsbad, Sten, 2009, In: Ugeskrift for læger. 171, 8, p. 615-7 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Lixisenatide, a novel GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus

    Christensen, M., Knop, Filip Krag, Holst, Jens Juul & Vilsboll, T., 2009, In: IDrugs. The Investigational Drugs Journal. 12, 8, p. 503-13 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Long-term exendin-4 treatment delays natural deterioration of glycaemic control in diabetic Goto-Kakizaki rats

    Simonsen, L., Pilgaard, S., Orskov, C., Hartmann, Bolette, Holst, Jens Juul & Deacon, Carolyn F., 2009, In: Diabetes, Obesity and Metabolism. 11, 9, p. 884-90 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Mechanisms of Gastric Emptying Disturbances in Chronic and Acute Inflammation of the Distal Gastrointestinal Tract

    Keller, J., Beglinger, C., Holst, Jens Juul, Andresen, V. & Layer, P., 2009, In: American Journal of Physiology: Gastrointestinal and Liver Physiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Nutritional effects of the serial transverse enteroplasty procedure in experimental short bowel syndrome

    Kaji, T., Tanaka, H., Wallace, L. E., Kravarusic, D., Holst, Jens Juul & Sigalet, D. L., 2009, In: European Journal of Pediatric Surgery. Supplement. 44, 8, p. 1552-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Pancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and mass

    Gelling, R. W., Vuguin, P. M., Du, X. Q., Cui, L., Rømer, J., Pederson, R. A., Leiser, M., Sørensen, H., Holst, Jens Juul, Fledelius, C., Johansen, P. B., Fleischer, N., McIntosh, C. H. S., Nishimura, E. & Charron, M. J., 2009, In: American Journal of Physiology: Endocrinology and Metabolism. 297, 3, p. E695-707

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Pathophysiology and aetiology of impaired fasting glycaemia and impaired glucose tolerance: does it matter for prevention and treatment of type 2 diabetes?

    Faerch, K., Borch-Johnsen, K., Holst, Jens Juul & Vaag, Allan, 2009, In: Diabetologia. 52, 9, p. 1714-23 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus

    Müssig, K., Staiger, H., Machicao, F., Machann, J., Schick, F., Schäfer, S. A., Claussen, C. D., Holst, Jens Juul, Gallwitz, B., Stefan, N., Fritsche, A. & Häring, H., 2009, In: Metabolism - Clinical and Experimental. 58, 12, p. 1809-11 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus

    Hare, K. J., Knop, Filip Krag, Asmar, M., Madsbad, Sten, Deacon, Carolyn F., Holst, Jens Juul & Vilsbøll, Tina, 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 12, p. 4679-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Receptor-mediated activation of gastric vagal afferents by glucagon-like peptide-1 in the rat

    Bucinskaite, V., Tolessa, T., Pedersen, J., Rydqvist, B., Zerihun, L., Holst, Jens Juul & Hellström, P. M., 2009, In: Neurogastroenterology and Motility. 21, 9, p. 978-e78

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Reduced plasma levels of glucagon-like peptide-1 in elderly men are associated with impaired glucose tolerance but not with coronary heart disease

    Nathanson, D., Zethelius, B., Berne, C., Holst, Jens Juul, Sjöholm, A. & Nyström, T., 2009, In: Diabetologia. 53, 2, p. 277-80 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Remission af type 2-diabetes efter gastric bypass-kirurgi: et medicinsk mysterium?

    Jacobsen, S., Hansen, D. L., Worm, Dorte, Madsbad, Sten, Hvolris, L. E., Naver, L. P. S. & Holst, Jens Juul, 2009, In: Behandlerbladet. p. 20-29 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes

    Deacon, Carolyn F. & Holst, Jens Juul, 2009, In: Advances in Therapy. 26, 5, p. 488-99 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism

    Patti, M., Houten, S. M., Bianco, A. C., Bernier, R., Larsen, P. R., Holst, Jens Juul, Badman, M. K., Maratos-Flier, E., Mun, E. C., Pihlajamaki, J., Auwerx, J. & Goldfine, A. B., 2009, In: Obesity. 17, 9, p. 1671-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Short bowel patients treated for two years with glucagon-like Peptide 2: effects on intestinal morphology and absorption, renal function, bone and body composition, and muscle function

    Jeppesen, Pia, Lund, P., Gottschalck, I. B., Nielsen, H. B., Holst, Jens Juul, Mortensen, J., Poulsen, S. S., Quistorff, B. & Mortensen, P. B., 2009, In: Gastroenterology Research and Practice. 2009, p. 616054

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Short bowel patients treated for two years with glucagon-like peptide 2 (GLP-2): compliance, safety, and effects on quality of life

    Jeppesen, Palle Bekker, Lund, P., Gottschalck, I. B., Nielsen, H. B., Holst, Jens Juul, Mortensen, J., Poulsen, S. S., Quistorff, B. & Mortensen, P. B., 2009, In: Gastroenterology Research and Practice. 2009, p. 425759

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Short-term treatment with olanzapine does not modulate gut hormone secretion: olanzapine disintegrating versus standard tablets

    Vidarsdottir, S., Roelfsema, F., Streefland, T., Holst, Jens Juul, Rehfeld, Jens Frederik & Pijl, H., 2009, In: European Journal of Endocrinology. 162, 1, p. 75-83 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The effects of dietary fibre type on satiety-related hormones and voluntary food intake in dogs

    Bosch, G., Verbrugghe, A., Hesta, M., Holst, Jens Juul, van der Poel, A. F. B., Janssens, G. P. J. & Hendriks, W. H., 2009, In: British Journal of Nutrition. 102, 2, p. 318-25 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The spectrum of antidiabetic actions of GLP-1 in patients with diabetes

    Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2009, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 23, 4, p. 453-62 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Treatment of type 2 diabetes with glucagon-like peptide-1 receptor agonists

    Hansen, K. B., Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, Tina, 2009, In: International Journal of Clinical Practice. 63, 8, p. 1154-60 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Twelve weeks treatment with the DPP-4 inhibitor sitagliptin improves glycaemic control, but does not improve GLP-1 secretion, in patients with type 2 diabetes - a randomised trial

    Aaboe, K., Knop, F. K., Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2009, In: Diabetologia. p. 748

    Research output: Contribution to journalConference abstract in journalResearch

  27. Published

    Whey protein potentiates the intestinotrophic action of glucagon-like peptide-2 in parenterally fed rats

    Liu, X., Murali, S. G., Holst, Jens Juul & Ney, D. M., 2009, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 297, 5, p. R1554-62

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Changes of cognition and regional cerebral activity during acute hypoglycemia in normal subjects: A H2 15O positron emission tomographic study

    Bie-Olsen, L. G., Kjaer, T. W., Pedersen-Bjergaard, Ulrik, Lonsdale, M. N., Holst, Jens Juul, Law, Ian & Thorsteinsson, B., Jun 2009, In: Journal of Neuroscience Research. 87, 8, p. 1922-1928 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Mechanisms of gastric emptying disturbances in chronic and acute inflammation of the distal gastrointestinal tract

    Keller, J., Beglinger, C., Holst, Jens Juul, Andresen, V. & Layer, P., Nov 2009, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 297, 5, p. G861-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Treatment of type 1 diabetic patients with glucagon-like peptide-1 (GLP-1) and GLP-1R agonists

    Kielgast, U., Holst, Jens Juul & Madsbad, Sten, Nov 2009, In: Current Diabetes Reviews. 5, 4, p. 266-75 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Cognitive performance, symptoms and counter-regulation during hypoglycaemia in patients with type 1 diabetes and high or low renin-angiotensin system activity

    Høi-Hansen, T., Pedersen-Bjergaard, Ulrik, Andersen, R. D., Kristensen, Peter Lommer, Thomsen, C., Kjaer, T., Høgenhaven, H., Smed, A., Holst, Jens Juul, Dela, Flemming, Boomsma, F. & Thorsteinsson, B., Dec 2009, In: Journal of the Renin-Angiotensin-Aldosterone System. 10, 4, p. 216-29 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2010
  33. Published

    Acute effects of casein on postprandial lipemia and incretin responses in type 2 diabetic subjects

    Brader, L. J., Holm, L., Mortensen, L., Thomsen, C., Astrup, A., Holst, Jens Juul, Vrese, M. D., Schrezenmeir, J. & Hermansen, K., 2010, In: Nutrition, Metabolism & Cardiovascular Diseases. 20, 2, p. 101-109 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Effect of glucagon-like peptide-1 on alpha- and beta-cell function in C-peptide-negative type 1 diabetic patients

    Kielgast, U., Asmar, M., Madsbad, Sten & Holst, Jens Juul, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 5, p. 2492-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Increased Postprandial Response of Glucagon-Like Peptide-2 in Patients with Chronic Pancreatitis and Pancreatic Exocrine Insufficiency

    Hornum, Mads, Pedersen, J. F., Larsen, S., Olsen, O., Holst, Jens Juul & Knop, Filip Krag, 2010, In: Pancreatology. 10, 2-3, p. 201-207 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Insulinets vej ind i det danske samfund

    Larsen, Erik Hviid & Holst, Jens Juul, 2010, Det fremmede som historisk drivkraft. Danmark efter 1742: Et festskrift til Hendes Majestæt Dronning Margrethe II ved 70-års-fødselsdagen den 16. april 2010. Nielsen, M. A. (ed.). København: Det Kongelige Danske Videnskabernes Selskab, p. 85-94

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  37. Published

    Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes

    Deacon, Carolyn F. & Holst, Jens Juul, 2010, In: Expert Opinion on Investigational Drugs. 19, 1, p. 133-140 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    On the role of glucose-dependent insulintropic polypeptide in postprandial metabolism in humans

    Asmar, M., Tangaa, W., Madsbad, Sten, Hare, K., Astrup, A., Flint, A., Bülow, J. & Holst, Jens Juul, 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 3, p. E614-21 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes

    Asmar, M., Højberg, P. V., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-80 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Pancreatic ß-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes

    Asmar, M., Højberg, P., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-180 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Postprandial diabetic glucose tolerance is normalized by gastric bypass feeding as opposed to gastric feeding and is associated with exaggerated GLP-1 secretion: a case report

    Dirksen, C., Hansen, D. L., Madsbad, Sten, Hvolris, L. E., Naver, L. S., Holst, Jens Juul & Worm, Dorte, 2010, In: Diabetes Care. 33, 2, p. 375-377

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Secretion and dipeptidyl peptidase-4-mediated metabolism of incretin hormones after a mixed meal or glucose ingestion in obese compared to lean, nondiabetic men

    Carr, R. D., Larsen, M. O., Jelic, K., Lindgren, O., Vikman, J., Holst, Jens Juul, Deacon, Carolyn F. & Ahrén, B., 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 2, p. 872-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    The T-allele of TCF7L2 rs7903146 associates with a reduced compensation of insulin secretion for insulin resistance induced by 9 days of bed rest

    Alibegovic, A. C., Sonne, M. P., Højbjerre, L., Hansen, T., Pedersen, Oluf Borbye, van Hall, Gerrit, Holst, Jens Juul, Stallknecht, Bente Merete, Dela, Flemming & Vaag, A., 2010, In: Diabetes. 59, 4, p. 836-43 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    The effect of DPP-4 inhibition with sitagliptin on incretin secretion and on fasting and postprandial glucose turnover in subjects with impaired fasting glucose

    Bock, G., Man, C. D., Micheletto, F., Basu, R., Rn, P. D. G., Laugen, J., Deacon, Carolyn F., Holst, Jens Juul, Toffolo, G., Cobelli, C., Rizza, R. A. & Vella, A., 2010, In: Clinical Endocrinology. 73, p. 189-196

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose- and non-glucose-induced insulin secretion in patients with type 2 diabetes mellitus

    Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-333 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes

    Deacon, Carolyn F. & Holst, Jens Juul, Jan 2010, In: Expert Opinion on Investigational Drugs. 19, 1, p. 133-40 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Little enhancement of meal-induced GLP-1 secretion in Japanese: Comparison of type 2 diabetes and healthy controls

    Yabe, D., Kuroe, A., Lee, S., Watanabe, K., Hyo, T., Hishizawa, M., Kurose, T., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N. & Seino, Y., Jan 2010, In: Journal of Diabetes Investigation. 1, 1/2, p. 56-59

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Effects of fat supplementation on postprandial GIP, GLP-1, ghrelin and IGFBP-1 levels: a pilot study on adolescents with type 1 diabetes

    Lodefalk, M., Carlsson-Skwirut, C., Holst, Jens Juul, Aman, J. & Bang, P., 1 Jan 2010, In: Hormone research in pædiatrics. 73, 5, p. 355-362 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Glucagon and glucagon-like peptides 1 and 2

    Holst, Jens Juul, 1 Jan 2010, In: Results and Problems in Cell Differentiation. 50, p. 121-35 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    The effect of glucagon-like Peptide-2 receptor agonists on colonic anastomotic wound healing

    Redstone, H. A., Buie, W. D., Hart, D. A., Wallace, L., Hornby, P. J., Sague, S., Holst, Jens Juul & Sigalet, D. L., 1 Jan 2010, In: Gastroenterology Research and Practice. 2010, p. Article ID 672453 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    The effect of glucagon-like peptide-2 on arterial blood flow and cardiac parameters

    Bremholm, L., Hornum, Mads, Andersen, U. B. & Holst, Jens Juul, 8 Jan 2010, In: Regulatory Peptides. 159, 1-3, p. 67-71 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide: new advances

    Asmar, M. & Holst, Jens Juul, 1 Feb 2010, In: Current Opinion in Endocrinology, Diabetes and Obesity. 17, 1, p. 57-62 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4207